Title: Flavone glucosides from Artemisia juncea.
Authors: Okhundedaev, Bakhodir S.; Bacher, Markus; Mukhamatkhanova, Rimma F.; Shamyanov, Ildar J.; Zengin, Gokhan; Böhmdorfer, Stefan; Mamadalieva, Nilufar Z.; Rosenau, Thomas
Abstract: A new flavone glucoside, 4′,5-dihydroxy-3′,5′,6-trimethoxyflavone-7-O-β-D-glucoside was obtained from aerial parts of Artemisia juncea, together with the known flavone eupatilin (5,7-dihydroxy-3′,4′,6-trimethoxyflavone). The compounds were comprehensively analytically characterized by IR, UV, NMR and HR-MS, and their chemical structures ascertained. The EtOAc fraction of A. juncea showed the strongest DPPH radical scavenging ability as well as reducing power (in CUPRAC and FRAP assays) and phosphomolybdenum activity. This fraction also exhibited the strongest inhibitory effects on tyrosinase. Additionally, the best antidiabetic effects were observed for eupatilin and the CHCl3 fraction.
Subjects: GLUCOSIDES; ARTEMISIA; PHENOL oxidase; CHEMICAL structure
Publication: Natural Product Research, 2019, Vol 33, Issue 15, p2169
ISSN: 1478-6419
Publication type: Academic Journal
DOI: 10.1080/14786419.2018.1490901

Flavone glucosides from Artemisia juncea.

Okhundedaev, Bakhodir S.; Bacher, Markus; Mukhamatkhanova, Rimma F.; Shamyanov, Ildar J.; Zengin, Gokhan; Böhmdorfer, Stefan; Mamadalieva, Nilufar Z.; Rosenau, Thomas