Title: Efficient biosynthesis, analysis, solubility and anti-bacterial activities of succinylglycosylated naringenin.
Authors: Zhang, S.; Li, D. D.; Zeng, F.; Zhu, Z. H.; Song, P.; Zhao, M.; Duan, J. A.
Abstract: A novel water-soluble flavonoid with good anti-bacterial activities, naringenin-6″-succl-7-O-glucoside (7-SGN), was synthesised. It was biotransformed from naringenin by Bacillus amyloliquefaciens FJ18 in aqueous miscible organic media, and characterised by LC-MS and NMR analysis. The solubility of 7-SGN in water was approximately 102 times higher than that of naringenin. These results demonstrated that both the water solubility and the anti-bacterial activity of 7-SGN were significantly improved.
Subjects: NARINGENIN; FLAVONOIDS; BACILLUS amyloliquefaciens; AQUEOUS solutions; BIOCONVERSION
Publication: Natural Product Research, 2019, Vol 33, Issue 12, p1756
ISSN: 1478-6419
Publication type: Academic Journal
DOI: 10.1080/14786419.2018.1431633

Efficient biosynthesis, analysis, solubility and anti-bacterial activities of succinylglycosylated naringenin.

Zhang, S.; Li, D. D.; Zeng, F.; Zhu, Z. H.; Song, P.; Zhao, M.; Duan, J. A.