Chemical investigation of metabolites produced by an endophytic fungi Phialemonium curvatum from the leaves of Passiflora edulis.

Rathnayake, G. R. Nalin; Kumar, N. Savitri; Jayasinghe, Lalith; Araya, Hiroshi; Fujimoto, Yoshinori

Phialemonium curvatum, an endophytic fungus isolated from the leaves of Passiflora edulis was cultured in potato dextrose broth (PDB) media and chromatographic separation of the EtOAc extract of the broth and mycelium led to the isolation of 4-hydroxybenzoic acid (1), 3-indole acetic acid (2), solaniol (3), uracil (4), uridine (5) and glycerol (6). Compound 2 showed a weak antifungal activity against Cladosporium cladosporioides. This is the first report of the isolation of the endophytic fungus P. curvatum from P. edulis and complete 13CNMR assignments of 3.

Natural Product Research, 2018, Vol 32, Issue 20, p2483

1478-6419

Academic Journal

10.1080/14786419.2017.1416373