Results
Title

A pair of enantiomeric 5-oxabicyclic[4.3.0]lactam derivatives and one new polyketide from the marine-derived fungus Penicillium griseofulvum.

Authors

Yang, Jian-Kun; Zhang, Bin; Gao, Tong; Yang, Meng-Yue; Zhao, Guo-Zheng; Zhu, Hua-Jie; Liu, Li; Cao, Fei

Abstract

A pair of enantiomeric 4-oxabicyclic[4.3.0]lactam derivatives, ( )- and (−)-penicilactam A (1), and one new polyketide derivative penicitrinone F (2) were isolated from the marine-derived fungus Penicillium griseofulvum GT-10. Their structures and absolute configurations were elucidated through extensive spectroscopic analyses combined with the calculated ECD spectra. Penicitrinone F (2) had moderate inhibitory activity towards Bacillus subtilis with a MIC value of 6.3 μM.

Publication

Natural Product Research, 2018, Vol 32, Issue 19, p2366

ISSN

1478-6419

Publication type

Academic Journal

DOI

10.1080/14786419.2017.1410815