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- Title
A new C-glycosyl flavone and a new neolignan glycoside from Passiflora edulis Sims peel.
- Authors
Hu, Yue; Jiao, Lin; Jiang, Min-Hong; Yin, Sheng; Dong, Pan; Zhao, Zhi-Min; Yang, De-Po; Ho, Pei-Tsai; Wang, Dong-Mei
- Abstract
A new C-glycosyl flavone, Chrysin-8-C-(2″-O-β-6-deoxy-glucopyranosyl)-β-D-glucopyranoside (1), a new neolignan glycoside, citrusin G (2), as well as 15 known compounds (3-17) were isolated from the peel of Passiflora edulis Sims. The structure determinations were primarily based on comprehensive spectroscopic analyses, and the absolute configuration of 2 were unequivocally determined by the CD experiment and chemical transformation. Compound 1 represents the rare examples of the flavonoid featuring a deoxy glucose sugar moiety. Compounds 5, 7 and 9 exhibited moderate inhibitory effects on nitric oxide (NO) production stimulated by lipopolysaccharide (LPS) in RAW 264.7 cells, with IC50 values of 34.92, 16.12 and 26.67 μM, respectively.
- Publication
Natural Product Research, 2018, Vol 32, Issue 19, p2312
- ISSN
1478-6419
- Publication type
Academic Journal
- DOI
10.1080/14786419.2017.1410809