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- Title
A new12-membered lactone from the stems of Ficus auriculata.
- Authors
Shao, Tai-Ming; Zheng, Cai-Juan; Li, Xiao-Bao; Chen, Guang-Ying; Song, Xiao-Ping; Han, Chang-Ri
- Abstract
A new lactone ficusine D (1), together with six known compounds (2-7) were isolated from the stems of the Ficus auriculata. The new compound 1 was a rare 12-membered lactone containing a quinone ring skeleton. The structure of the 1 was elucidated by comprehensive spectroscopic data. The relative and absolute configurations of 1 were elucidated by the ROESY analysis and biogenesis pathway. All compounds were evaluated for their antibacterial activities against six pathogenic bacteria in vitro. Compounds 6 and 7 exhibited potent antibacterial activities against Bacillus cereus with the MIC values of 2.5 and 5 μM, respectively.
- Publication
Natural Product Research, 2018, Vol 32, Issue 19, p2268
- ISSN
1478-6419
- Publication type
Academic Journal
- DOI
10.1080/14786419.2017.1405415