Results
Title

Kinetics studies on triacontanyl palmitate: a urease inhibitor.

Authors

Lodhi, Muhammad Arif; Abbasi, Muhammad Athar; Choudhary*, Muhammad Iqbal; Ahmad, Viqar Uddin

Abstract

The mechanism of inhibition of jack bean and Bacillus pasteurii ureases was investigated by triacontanyl palmitate (1) which is a long-chain fatty ester and has been isolated from Symplocos racemosa Roxb. Lineweaver-Burk, Dixon plots, and their secondary replots showed that 1 is a non-competitive inhibitor of these enzymes. Ki values were found to be 60.03 ± 1.72 and 88.23 ± 0.31 µM against jack bean and B. pasteurii ureases, respectively.

Publication

Natural Product Research, 2007, Vol 21, Issue 8, p721

ISSN

1478-6419

Publication type

Academic Journal

DOI

10.1080/14786410600906913