Constituents of Salvia microphylla.

Aydoğmuş, Zeynep; Yeşİlyurt, Volkan; Topcu, GülaÇti

A new phenolic ester 2-( p -hydroxyphenyl)ethyl eicosaheptanoic acid ester (1) and a known one hexacosylferulate (2) were isolated from the acetone extract of Salvia microphylla . In addition, two sesquiterpenes β-eudesmol (3) and 8α-hydroxy-β-eudesmol (4), a diterpene carnosic acid 12-methyl ether (12-methoxycarnosic acid) (5), three triterpenes erithrodiol 3-acetate, oleanolic acid, lupeol and β-sitosterol were obtained as known compounds from this plant extract. The structures of the isolated compounds were elucidated by spectroscopic methods, including one- and two- dimensional 1 H- and 13 C-NMR and MS spectroscopies. The selected compounds were tested for antimicrobial activity against standard bacterial strains, and only carnosic acid 12-methyl ether showed antimicrobial activity against S. aureus at 78  µg  mL -1 .

PHENOLS; SALVIA; ACETONE; PHENOLIC acids; ESTERS; PLANT extracts; ORGANIC compounds

Natural Product Research, 2006, Vol 20, Issue 8, p775

1478-6419

Academic Journal

10.1080/14786410500462843