Works matching DE "SPHINGOSINE"

Results: 813

The effect on heart rate of combining single-dose fingolimod with steady-state atenolol or diltiazem in healthy subjects.

Published in:

European Journal of Clinical Pharmacology, 2008, v. 64, n. 5, p. 457, doi. 10.1007/s00228-007-0448-4

By:

Kovarik, John;
Lu, Michael;
Riviere, Gilles-Jacques;
Barbet, Irene;
Maton, Steve;
Goldwater, D. Ronald;
Schmouder, Robert L.

Publication type:

Article

Sphingosine 1-phosphate levels in plasma and HDL are altered in coronary artery disease.

Published in:

Basic Research in Cardiology, 2010, v. 105, n. 6, p. 821, doi. 10.1007/s00395-010-0112-5

By:

Sattler, Katherine J. E.;
Elbasan, Şehriban;
Keul, Petra;
Elter-Schulz, Miriam;
Bode, Constantin;
Gräler, Markus H.;
Bröcker-Preuss, Martina;
Budde, Thomas;
Erbel, Raimund;
Heusch, Gerd;
Levkau, Bodo

Publication type:

Article

Activation of sphingosine kinase by muscarinic receptors enhances NO-mediated and attenuates EDHF-mediated vasorelaxation.

Published in:

Basic Research in Cardiology, 2009, v. 104, n. 1, p. 50, doi. 10.1007/s00395-008-0744-x

By:

Mulders, Arthur C. M.;
Mathy, Marie-Jeanne;
Meyer zu Heringdorf, Dagmar;
ter Braak, Michael;
Hajji, Najat;
Olthof, Dominique C.;
Michel, Martin C.;
Alewijnse, Astrid E.;
Peters, Stephan L. M.

Publication type:

Article

Changes in morphology and inward rectifier currents in human atrial myocytes depend on culture conditions.

Published in:

Basic Research in Cardiology, 2002, v. 97, n. 6, p. 434, doi. 10.1007/s00395-002-0375-6

By:

Himmel, Herbert M.;
Pietsch, Martina;
Streller, Uwe;
Graf, Eva M.;
Ravens, Ursula

Publication type:

Article

Correction: Mechanism of sphingosine 1-phosphate clearance from blood.

Published in:: Biochemical Journal, 2023, v. 480, n. 24, p. 2059, doi. 10.1042/BCJ20190730_COR
Publication type:: Article

HPLC-MS/MS Analysis for Sphingosine 1-Phosphate after the Dephosphorylation by Hydrogen Fluoride.

Published in:

Separations (2297-8739), 2024, v. 11, n. 1, p. 34, doi. 10.3390/separations11010034

By:

Kim, Hee-Jung;
Jung, Seo-Hyeon;
Gulyamov, Shokhid;
Lee, Hyun-Gy;
Boyjigitov, Oybek;
Lee, Yong-Moon

Publication type:

Article

The outs and the ins of sphingosine-1-phosphate in immunity.

Published in:

2011

By:

Spiegel, Sarah;
Milstien, Sheldon

Publication type:

journal article

Inflammation: Hope for sepsis treatment.

Published in:

2010

By:

Bird, Lucy

Publication type:

journal article

The alliance of sphingosine-1-phosphate and its receptors in immunity.

Published in:

2008

By:

Rivera, Juan;
Proia, Richard L.;
Olivera, Ana

Publication type:

journal article

Exiting lymphoid organs.

Published in:

Nature Reviews Immunology, 2007, v. 7, n. 5, p. 323, doi. 10.1038/nri2074

By:

Bell, Elaine

Publication type:

Article

Targeting lung DCs to treat asthma.

Published in:

Nature Reviews Immunology, 2006, v. 6, n. 12, p. 877, doi. 10.1038/nri1987

By:

Leavy, Olive

Publication type:

Article

In Brief.

Published in:: Nature Reviews Immunology, 2006, v. 6, n. 6, p. 430, doi. 10.1038/nri1875
Publication type:: Article

Sphingosine 1-phosphate and its receptors: an autocrine and paracrine network.

Published in:

Nature Reviews Immunology, 2005, v. 5, n. 7, p. 560, doi. 10.1038/nri1650

By:

Rosen, Hugh;
Goetzl, Edward J.

Publication type:

Article

T-cell responses: Too fat to respond.

Published in:

Nature Reviews Immunology, 2005, v. 5, n. 4, p. 266, doi. 10.1038/nri1612

By:

Minton, Kirsty

Publication type:

Article

In Brief.

Published in:

Nature Reviews Immunology, 2004, v. 4, n. 2, p. 85, doi. 10.1038/nri1304

By:

Bell, Elaine

Publication type:

Article

Sphingosine 1‐phosphate receptor modulators in multiple sclerosis treatment: A practical review.

Published in:

Annals of Clinical & Translational Neurology, 2024, v. 11, n. 4, p. 842, doi. 10.1002/acn3.52017

By:

Coyle, Patricia K.;
Freedman, Mark S.;
Cohen, Bruce A.;
Cree, Bruce A. C.;
Markowitz, Clyde E.

Publication type:

Article

Potential of a sphingosine 1-phosphate receptor antagonist and sphingosine kinase inhibitors as targets for multiple myeloma treatment.

Published in:

Oncology Letters, 2022, v. 23, n. 4, p. N.PAG, doi. 10.3892/ol.2022.13231

By:

Tanaka, Yuko;
Okabe, Seiichi;
Ohyashiki, Kazuma;
Gotoh, Akihiko

Publication type:

Article

Sphingosine kinases are involved in the regulation of all-trans retinoic acid sensitivity of K562 chronic myeloid leukemia cells.

Published in:

Oncology Letters, 2021, v. 22, n. 2, p. N.PAG, doi. 10.3892/ol.2021.12842

By:

Sun, Defu;
Wang, Siping

Publication type:

Article

Sphingosine kinase-1 predicts overall survival outcomes in non-small cell lung cancer patients treated with carboplatin and navelbine.

Published in:

Oncology Letters, 2019, v. 18, n. 2, p. 1259, doi. 10.3892/ol.2019.10447

By:

Gachechiladze, Mariam;
Tichý, Tomáš;
Kolek, Vítězslav;
Grygárková, Ivona;
Klein, Jiří;
Mgebrishvili, Giorgi;
Kharaishvili, Gvantsa;
Janíková, Mária;
Smičková, Petra;
Cierna, Lucia;
Pitson, Stuart;
Maddelein, Marie-Lise;
Cuvillier, Olivier;
Škarda, Jozef

Publication type:

Article

Sphingosine 1-Phosphate Induces Cyclooxygenase-2/Prostaglandin E2 Expression via PKCα-dependent Mitogen-Activated Protein Kinases and NF-κB Cascade in Human Cardiac Fibroblasts.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. N.PAG, doi. 10.3389/fphar.2020.569802

By:

Yang, Chien-Chung;
Hsiao, Li-Der;
Su, Mei-Hsiu;
Yang, Chuen-Mao

Publication type:

Article

Abrogation of Endogenous Glycolipid Antigen Presentation on Myelin-Laden Macrophages by D-Sphingosine Ameliorates the Pathogenesis of Experimental Autoimmune Encephalomyelitis.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00404

By:

Ban, Yi;
Dong, Wenjuan;
Zhang, Lixing;
Zhou, Tian;
Altiti, Ahmad S.;
Ali, Khaleel;
Mootoo, David R.;
Blaho, Victoria A.;
Hla, Timothy;
Ren, Yi;
Ma, Xiaojing

Publication type:

Article

FTY720 attenuates lesional interleukin-17+ cell accumulation in rat experimental autoimmune neuritis.

Published in:

Neuropathology & Applied Neurobiology, 2009, v. 35, n. 5, p. 487, doi. 10.1111/j.1365-2990.2009.01016.x

By:

Zhang, Z-Y.;
Zhang, Z.;
Schluesener, H. J.

Publication type:

Article

Agalsidase Beta: A Review of its Use in the Management of Fabry Disease.

Published in:

Drugs, 2007, v. 67, n. 3, p. 435, doi. 10.2165/00003495-200767030-00007

By:

Keating, Gillian M.;
Simpson, Dene

Publication type:

Article

Sphingosine 1‐Phosphate Prevents Human Embryonic Stem Cell Death Following Ischemic Injury.

Published in:

European Journal of Lipid Science & Technology, 2022, v. 124, n. 7, p. 1, doi. 10.1002/ejlt.202200019

By:

Assis, Juliane L. de;
Fernandes, Aline M.;
Aniceto, Bárbara S.;
Pompeu, Pedro;
Banchio, Claudia;
Girardini, Javier;
Vieyra, Adalberto;
Valverde, Rafael H. F.;
Einicker‐Lamas, Marcelo

Publication type:

Article

D-erythro-Sphingosine and Pregnenolonesulphate activate TRPM3 channels synergistically in INS-1E cells.

Published in:

Bangladesh Journal of Medical Science, 2017, v. 16, n. 1, p. 98, doi. 10.3329/bjms.v16i1.31140

By:

Halim, Md. Abdul

Publication type:

Article

Prediction of Sphingosine protein-coding regions with a self adaptive spectral rotation method.

Published in:

PLoS ONE, 2019, v. 14, n. 4, p. 1, doi. 10.1371/journal.pone.0214442

By:

Li, Zhongwei;
Guan, Yanan;
Yuan, Xiang;
Zheng, Pan;
Zhu, Hu

Publication type:

Article

Measurement of trihydroxy-linoleic acids in stratum corneum by tape-stripping: Possible biomarker of barrier function in atopic dermatitis.

Published in:

PLoS ONE, 2019, v. 14, n. 01, p. 1, doi. 10.1371/journal.pone.0210013

By:

Chiba, Takahito;
Nakahara, Takeshi;
Kohda, Futoshi;
Ichiki, Toshio;
Manabe, Motomu;
Furue, Masutaka

Publication type:

Article

Sphingosine 1-phosphate attenuates MMP2 and MMP9 in human anaplastic thyroid cancer C643 cells: Importance of S1P2.

Published in:

PLoS ONE, 2018, v. 13, n. 5, p. 1, doi. 10.1371/journal.pone.0196992

By:

Asghar, Muhammad Yasir;
Kemppainen, Kati;
Lassila, Taru;
Törnquist, Kid

Publication type:

Article

Profiling of epidermal lipids in a mouse model of dermatitis: Identification of potential biomarkers.

Published in:

PLoS ONE, 2018, v. 13, n. 4, p. 1, doi. 10.1371/journal.pone.0196595

By:

Franco, Jackeline;
Ferreira, Christina;
Paschoal Sobreira, Tiago J.;
Sundberg, John P.;
HogenEsch, Harm

Publication type:

Article

Non-phosphorylated FTY720 Induces Apoptosis of Human Microglia by Activating SREBP2.

Published in:

Cellular & Molecular Neurobiology, 2011, v. 31, n. 7, p. 1009, doi. 10.1007/s10571-011-9698-x

By:

Yoshino, Takashi;
Tabunoki, Hiroko;
Sugiyama, Shigeo;
Ishii, Keitaro;
Kim, Seung;
Satoh, Jun-ichi

Publication type:

Article

Synthesis of a Panel of Carbon-13-Labelled (Glyco)Sphingolipids.

Published in:

European Journal of Organic Chemistry, 2015, v. 2015, n. 12, p. 2661, doi. 10.1002/ejoc.201500025

By:

Wisse, Patrick;
Gold, Henrik;
Mirzaian, Mina;
Ferraz, Maria J.;
Lutteke, Ginger;
van den Berg, Richard J. B. H. N.;
van den Elst, Hans;
Lugtenburg, Johan;
van der Marel, Gijsbert A.;
Aerts, Johannes M. F. G.;
Codée, Jeroen D. C.;
Overkleeft, Herman S.

Publication type:

Article

Synthesis of Hydroxylated Analogues of α-Galactosyl Ceramide (KRN7000) with Varying Stereochemistry.

Published in:

European Journal of Organic Chemistry, 2013, v. 2013, n. 33, p. 7611, doi. 10.1002/ejoc.201301111

By:

Sawant, Ratnnadeep C.;
Hung, Jung‐Tung;
Chuang, Huei‐Lin;
Lin, Huan‐Shuan;
Chen, Wan‐Shin;
Yu, Alice L.;
Luo, Shun‐Yuan

Publication type:

Article

Enantio- and Diastereoselective Syntheses of 3-Hydroxypiperidines through Iridium-Catalyzed Allylic Substitution.

Published in:

European Journal of Organic Chemistry, 2013, v. 2013, n. 23, p. 5149, doi. 10.1002/ejoc.201300445

By:

Hoecker, Johannes;
Rudolf, Georg C.;
Bächle, Florian;
Fleischer, Steffen;
Lindner, Benjamin D.;
Helmchen, Günter

Publication type:

Article

Sphingolipids in physiology and pathophysiology.

Published in:

Acta Paediatrica, 2007, p. 39, doi. 10.1111/j.1651-2227.2007.00205.x

By:

Gieselmann, Volkmar

Publication type:

Article

Sphingosine 1-phosphate in neural signalling and function.

Published in:

Acta Paediatrica, 2007, p. 40, doi. 10.1111/j.1651-2227.2007.00206.x

By:

Milstien, Sheldon;
Gude, David;
Spiegel, Sarah

Publication type:

Article

Sphingosine 1-phosphate as an intracellular messenger and extracellular mediator in immunity.

Published in:

Acta Paediatrica, 2007, p. 49, doi. 10.1111/j.1651-2227.2007.00208.x

By:

Goetzl, Edward J.;
Wang, Wengang;
McGiffert, Christine;
Liao, Jia-Jun;
Huang, Mei-Chuan

Publication type:

Article

Vascular effects of sphingolipids.

Published in:

Acta Paediatrica, 2007, p. 44, doi. 10.1111/j.1651-2227.2007.00207.x

By:

Michel, Martin C.;
Mulders, Arthur C. M.;
Jongsma, Maikel;
Alewijnse, Astrid E.;
Peters, Stephan L. M.

Publication type:

Article

Investigation of the mechanisms of Genkwa Flos hepatotoxicity by a cell metabolomics strategy combined with serum pharmacology in HL-7702 liver cells.

Published in:

Xenobiotica, 2019, v. 49, n. 2, p. 216, doi. 10.1080/00498254.2018.1427905

By:

Wang, Zhipeng;
Zhang, Yuanyuan;
Liu, Quanli;
Sun, Linjia;
Lv, Mingming;
Yu, Peipei;
Chen, Xiaohui

Publication type:

Article

Straightforward Access to Simplified Sphingosine-1-phosphate Analogues.

Published in:

Synthetic Communications, 2007, v. 37, n. 16, p. 2737, doi. 10.1080/00397910701466030

By:

Grijalvo, Santiago;
Llebaria, Amadeu;
Delgado, Antonio

Publication type:

Article

Aberrant Upregulation of Astroglial Ceramide Potentiates Oligodendrocyte Injury.

Published in:

Brain Pathology, 2012, v. 22, n. 1, p. 41, doi. 10.1111/j.1750-3639.2011.00501.x

By:

Kim, SunJa;
Steelman, Andrew J.;
Zhang, Yumin;
Kinney, Hannah C.;
Li, Jianrong

Publication type:

Article

FTY720 Rescue Therapy in the Dark Agouti Rat Model of Experimental Autoimmune Encephalomyelitis: Expression of Central Nervous System Genes and Reversal of Blood-Brain-Barrier Damage.

Published in:

Brain Pathology, 2009, v. 19, n. 2, p. 254, doi. 10.1111/j.1750-3639.2008.00182.x

By:

Foster, Carolyn A.;
Mechtcheriakova, Diana;
Storch, Maria K.;
Balatoni, Balázs;
Howard, Laurence M.;
Bornancin, Frédéric;
Wlachos, Alexander;
Sobanov, Jury;
Kinnunen, Anu;
Baumruker, Thomas

Publication type:

Article

Receptor-mediated activation of ceramidase activity initiates the pleiotropic actions of adiponectin.

Published in:

Nature Medicine, 2011, v. 17, n. 1, p. 55, doi. 10.1038/nm.2277

By:

Holland, William L.;
Miller, Russell A.;
Zhao V. Wang;
Kai Sun;
Barth, Brian M.;
Bui, Hai H.;
Davis, Kathryn E.;
Bikman, Benjamin T.;
Halberg, Nils;
Rutkowski, Joseph M.;
Wade, Mark R.;
Tenorio, Vincent M.;
Ming-Shang Kuo;
Brozinick, Joseph T.;
Bei B. Zhang;
Birnbaum, Morris J.;
Summers, Scott A.;
Scherer, Philipp E.

Publication type:

Article

STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors.

Published in:

Nature Medicine, 2010, v. 16, n. 12, p. 1421, doi. 10.1038/nm.2250

By:

Heehyoung Lee;
Jiehui Deng;
Kujawski, Maciej;
Yang, Chunmei;
Yong Liu;
Herrmann, Andreas;
Kortylewski, Marcin;
Horne, David;
Somlo, George;
Forman, Stephen;
Jove, Richard;
Hua Yu

Publication type:

Article

Niemann-Pick disease type C1 is a sphingosine storage disease that causes deregulation of lysosomal calcium.

Published in:

Nature Medicine, 2008, v. 14, n. 11, p. 1247, doi. 10.1038/nm.1876

By:

Lloyd-Evans, Emyr;
Morgan, Anthony J.;
Xingxuan He;
Smith, David A.;
Elliot-Smith, Elena;
Sillence, Daniel J.;
Churchill, Grant C.;
Schuchman, Edward H.;
Galione, Antony;
Platt, Frances M.

Publication type:

Article

CD8+ T lymphocytes protective against malaria liver stages are primed in skin-draining lymph nodes.

Published in:

Nature Medicine, 2007, v. 13, n. 9, p. 1035, doi. 10.1038/nm1628

By:

Chakravarty, Sumana;
Cockburn, Ian A;
Kuk, Salih;
Overstreet, Michael G;
Sacci, John B;
Zavala, Fidel

Publication type:

Article

Corrigendum: Sphingosine 1-phosphate preserves fertility in irradiated female mice without propagating genomic damage in offspring.

Published in:

2002

By:

Paris, F.;
Perez, G.I.;
Fuks, Z.;
Haimovitz-Friedman, A.;
Nguyen, H.;
Bose, M.;
Ilagan, A.;
Hunt, P.A.;
Morgan, W.F.;
Tilly, J.L.;
Kolesnick, R.

Publication type:

Correction Notice

Sphingosine 1-phosphate preserves fertility in irradiated female mice without propagating genomic damage in offspring.

Published in:

Nature Medicine, 2002, v. 8, n. 9, p. 901, doi. 10.1038/nm0902-901

By:

Paris, François;
Perez, Gloria I.;
Fuks, Zvi;
Haimovitz-Friedman, Adriana;
Nguyen, Hai;
Bose, Mousumi;
Ilagan, Arlene;
Hunt, Patricia A.;
Morgan, William F.;
Tilly, Jonathan L.;
Kolesnick, Richard

Publication type:

Article

Extra Rabs unsnarl a lipid traffic jam.

Published in:

Nature Medicine, 2002, v. 8, n. 7, p. 662, doi. 10.1038/nm0702-662

By:

Bergo, Martin O.;
Young, Stephen G.

Publication type:

Article

Protecting the female germ line from cancer therapy.

Published in:

Nature Medicine, 2000, v. 6, n. 10, p. 1100, doi. 10.1038/80427

By:

Casper, Robert F.;
Jurisicova, Andrea

Publication type:

Article

Oocyte apoptosis is suppressed by disruption of the acid sphingomyelinase gene or by sphingosine -1-phosphate therapy.

Published in:

Nature Medicine, 2000, v. 6, n. 10, p. 1109, doi. 10.1038/80442

By:

Morita, Yutaka;
Perez, Gloria I.;
Paris, Francois;
Miranda, Silvia R.;
Ehleiter, Desiree;
Haimovitz-Friedman, Adrianna;
Fuks, Zvi;
Xie, Zhihua;
Reed, John C.;
Schuchman, Edward H.;
Kolesnick, Richard N.;
Tilly, Jonathan L.

Publication type:

Article