Title: Isolation and structure elucidation of Diazaquinomycin C from a terrestrial streptomyces sp. and confirmation of the akashin structure.
Authors: Maskey, R.P.; Grün-Wollny, I.; Laatsch, H.
Abstract: In the screening of terrestrial Streptomycetes for bioactive components, a new antibiotic designated as diazaquinomycin C ( 2b ) was isolated. The new antibiotic was found to be a homologue of diazaquinomycin A ( 2a ) by spectroscopic methods and by comparison of the NMR data with those of 2a . The same strain additionally produced the akashins 1a - 1c . The configuration of the N-O acetale bond in these rare glycosylated dichloroindigo derivatives was confirmed to be β.
Subjects: STREPTOMYCETACEAE; SPECTRUM analysis; ANTIBIOTICS; GLYCOSYLATION; DIAGNOSIS; PHARMACEUTICAL microbiology
Publication: Natural Product Research, 2005, Vol 19, Issue 2, p137
ISSN: 1478-6419
Publication type: Academic Journal
DOI: 10.1080/14786410410001704741

Isolation and structure elucidation of Diazaquinomycin C from a terrestrial streptomyces sp. and confirmation of the akashin structure.

Maskey, R.P.; Grün-Wollny, I.; Laatsch, H.