Works matching DNA topoisomerase inhibitors


Results: 393
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    Investigating the potential anticancer activities of antibiotics as topoisomerase II inhibitors and DNA intercalators: in vitro, molecular docking, molecular dynamics, and SAR studies.

    Published in:
    Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2171029
    By:
    • Farouk, Faten;
    • Elmaaty, Ayman Abo;
    • Elkamhawy, Ahmed;
    • Tawfik, Haytham O.;
    • Alnajjar, Radwan;
    • Abourehab, Mohammed A. S.;
    • Saleh, Mohamed A.;
    • Eldehna, Wagdy M.;
    • Al‐Karmalawy, Ahmed A.
    Publication type:
    Article
    12

    Design and synthesis of novel rigid dibenzo[b,f]azepines through ring closure technique as promising anticancer candidates against leukaemia and acting as selective topoisomerase II inhibitors and DNA intercalators.

    Published in:
    Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2022.2157825
    By:
    • El-Behairy, Mohammed Farrag;
    • Abd-Allah, Walaa Hamada;
    • Khalifa, Mohamed M.;
    • Nafie, Mohamed S.;
    • Saleh, Mohamed A.;
    • Abdel-Maksoud, Mohammed S.;
    • Al-Warhi, Tarfah;
    • Eldehna, Wagdy M.;
    • Al‐Karmalawy, Ahmed A.
    Publication type:
    Article
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    Synthesis, Structural Characterization and Biological Activity Evaluation of Novel Cu(II) Complexes with 3-(trifluoromethyl)phenylthiourea Derivatives.

    Published in:
    International Journal of Molecular Sciences, 2022, v. 23, n. 24, p. 15694, doi. 10.3390/ijms232415694
    By:
    • Drzewiecka-Antonik, Aleksandra;
    • Struga, Marta;
    • Głogowska, Agnieszka;
    • Augustynowicz-Kopec, Ewa;
    • Dobrzyńska, Katarzyna;
    • Chrzanowska, Alicja;
    • Wolska, Anna;
    • Rejmak, Paweł;
    • Klepka, Marcin T.;
    • Wrzosek, Małgorzata;
    • Bielenica, Anna
    Publication type:
    Article
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