Works matching DE "PRESENILINS"

Results: 859

Presenilin-2 in the cynomolgus monkey brain: investigation of age-related changes.

Published in:

Primates, 2004, v. 45, n. 3, p. 167, doi. 10.1007/s10329-004-0076-x

By:

Kimura, Nobuyuki;
Nakamura, Shin' ichiro;
Ono, Fumiko;
Sakakibara, Ippei;
Ishii, Yoshiyuki;
Kyuwa, Shigeru;
Yoshikawa, Yasuhiro

Publication type:

Article

Founder effect for the Ala431Glu mutation of the presenilin 1 gene causing early-onset Alzheimer’s disease in Mexican families.

Published in:

Neurogenetics, 2006, v. 7, n. 3, p. 195, doi. 10.1007/s10048-006-0043-3

By:

Yescas, Petra;
Huertas-Vazquez, Adriana;
Villarreal-Molina, María;
Rasmussen, Astrid;
Tusié-Luna, María Teresa;
López, Marisol;
Canizales-Quinteros, Samuel;
Alonso, María Elisa

Publication type:

Article

Alternative splicing in the N-terminus of Alzheimer’s presenilin 1.

Published in:

Neurogenetics, 2004, v. 5, n. 4, p. 223, doi. 10.1007/s10048-004-0195-y

By:

Scheper, Wiep;
Zwart, Rob;
Baas, Frank

Publication type:

Article

Physiological functions of the amyloid precursor protein secretases ADAM10, BACE1, and Presenilin.

Published in:

Experimental Brain Research, 2012, v. 217, n. 3/4, p. 331, doi. 10.1007/s00221-011-2952-0

By:

Prox, Johannes;
Rittger, Andrea;
Saftig, Paul

Publication type:

Article

Alterations in presenilin 1 processing by amyloid-β peptide in the rat retina.

Published in:

Experimental Brain Research, 2007, v. 181, n. 1, p. 69, doi. 10.1007/s00221-007-0904-5

By:

Watts, Helena;
Vince, Valerie;
Walsh, Desmond;
Bresciani, Laura;
Gentleman, Stephen;
Jen, Ling-Sun;
Anderson, Peter

Publication type:

Article

Does oxidatively damaged DNA drive amyloid-β generation in Alzheimer's disease? A hypothesis.

Published in:

Journal of Neurogenetics, 2021, v. 35, n. 4, p. 351, doi. 10.1080/01677063.2021.1954641

By:

Sanders, Owen Davis;
Rajagopal, Lekshmy;
Rajagopal, Jayalekshmi Archa

Publication type:

Article

Overexpression of U1 snRNA induces decrease of U1 spliceosome function associated with Alzheimer’s disease.

Published in:

Journal of Neurogenetics, 2017, v. 31, n. 4, p. 337, doi. 10.1080/01677063.2017.1395425

By:

Cheng, Zhi;
Shang, Yingchun;
Gao, Shan;
Zhang, Tao

Publication type:

Article

42nd Annual Meeting of the Italian Association of Neuropathology (AINP)/32nd Meeting of the Italian Association for Research on Brain Aging (AIRIC).

Published in:: 2006
Publication type:: Abstract

41st Annual Meeting ofthe Italian Association of Neuropathology (AINP) jointly with the French Society of Neuropathology 31st Meeting ofthe Italian Association for Research on Brain Aging (AIRIC).

Published in:: 2005
Publication type:: Abstract

Molecular Docking of Resveratrol Against Potential Molecular Targets in Alzheimer's Disease.

Published in:

Pakistan Journal of Scientific & Industrial Research Series A: Physical Sciences, 2022, v. 65, n. 2, p. 112

By:

Shah, Fahad Hassan;
Ul Ain, Qurat;
Ahmad, Saeed;
Akbar, Muhammad Yasir

Publication type:

Article

Hecogenin a Plant Derived Small Molecule as an Antagonist to BACE-1: A Potential Target for Neurodegenerative Disorders.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 6, p. 758, doi. 10.3390/metabo13060758

By:

Padmanabhan, Deepthi;
Siddiqui, Manzer H.;
Natarajan, Purushothaman;
Palanisamy, Senthilkumar

Publication type:

Article

Brain pathology in three subjects from the same pedigree with presenilin-1 ( PSEN1) P264L mutation.

Published in:

Neuropathology & Applied Neurobiology, 2010, v. 36, n. 1, p. 41, doi. 10.1111/j.1365-2990.2009.01046.x

By:

Martikainen, P.;
Pikkarainen, M.;
Pöntynen, K.;
Hiltunen, M.;
Lehtovirta, M.;
Tuisku, S.;
Soininen, H.;
Alafuzoff, I.

Publication type:

Article

Relationship between neuronal loss and ‘inflammatory plaques’ in early onset Alzheimer's disease.

Published in:

Neuropathology & Applied Neurobiology, 2007, v. 33, n. 3, p. 328, doi. 10.1111/j.1365-2990.2006.00816.x

By:

Shepherd, C. E.;
Grace, E. M.;
Mann, D. M. A.;
Halliday, G. M.

Publication type:

Article

Novel ‘inflammatory plaque’ pathology in presenilin-1 Alzheimer's disease.

Published in:

Neuropathology & Applied Neurobiology, 2005, v. 31, n. 5, p. 503, doi. 10.1111/j.1365-2990.2005.00667.x

By:

Shepherd, Claire E.;
Gregory, G. C.;
Vickers, J. C.;
Halliday, G. M.

Publication type:

Article

Age-related changes of intracellular Aβ in cynomolgus monkey brains.

Published in:

Neuropathology & Applied Neurobiology, 2005, v. 31, n. 2, p. 170, doi. 10.1111/j.1365-2990.2004.00624.x

By:

Kimura, N.;
Yanagisawa, K.;
Terao, K.;
Ono, F.;
Sakakibara, I.;
Ishii, Y.;
Kyuwa, S.;
Yoshikawa, Y.

Publication type:

Article

In vivo investigations of presenilin 1: from development to pathology.

Published in:

Neuropathology & Applied Neurobiology, 2002, v. 28, n. 2, p. 162, doi. 10.1046/j.1365-2990.2002.39286_40.x

By:

Bresciani, L. G;
Walsh, D. T;
Jen, L. S;
Gentleman, S. M

Publication type:

Article

Cases of Alzheimer's disease due to deletion of exon 9 of the presenilin-1 gene show an unusual but characteristic β-amyloid pathology known as ‘cotton wool’ plaques.

Published in:

Neuropathology & Applied Neurobiology, 2001, v. 27, n. 3, p. 189, doi. 10.1046/j.1365-2990.2001.00316.x

By:

Mann, D. M. A.;
Takeuchi, A.;
Sato, S.;
Cairns, N. J.;
Lantos, P. L.;
Rossor, M. N.;
Haltia, M.;
Kalimo, H.;
Iwatsubo, T.

Publication type:

Article

Constitutive and cytokine-regulated expression of presenilin-1 and presenilin-2 genes in human neural cell lines.

Published in:

Neuropathology & Applied Neurobiology, 1999, v. 25, n. 6, p. 492, doi. 10.1046/j.1365-2990.1999.00209.x

By:

Satoh;
Kuroda;
Satoh

Publication type:

Article

Loss of presenilin 2 is associated with increased iPLA2 activity and lung tumor development.

Published in:

Oncogene, 2014, v. 33, n. 44, p. 5193, doi. 10.1038/onc.2014.128

By:

Yun, H-M;
Park, M H;
Kim, D H;
Ahn, Y J;
Park, K-R;
Kim, T M;
Yun, N Y;
Jung, Y S;
Hwang, D Y;
Yoon, D Y;
Han, S B;
Hong, J T

Publication type:

Article

THE BEGINNINGS OF ALZHEIMER'S DISEASE: A REVIEW ON INFLAMMATORY, MITOCHONDRIAL, GENETIC AND EPIGENETIC PATHWAYS.

Published in:

Genetika (0534-0012), 2016, v. 48, n. 2, p. 515, doi. 10.2298/GENSR1602515P

By:

PERNA, Simone;
BOLOGNA, Chiara;
CAVAGNA, Pietro;
BERNARDINELLI, Luisa;
GUIDO, Davide;
PERONI, Gabriella;
RONDANELLI, Mariangela

Publication type:

Article

Two Novel Mutations and a de novo Mutation in PSEN1 in Early-onset Alzheimer's Disease.

Published in:

Aging & Disease, 2019, v. 10, n. 4, p. 908, doi. 10.14336/AD.2018.1109

By:

Yu-Sheng Li;
Zhi-Hua Yang;
Yao Zhang;
Jing Yang;
Dan-Dan Shang;
Shu-Yu Zhang;
Jun Wu;
Yan Ji;
Lu Zhao;
Chang-He Shi;
Yu-Ming Xu

Publication type:

Article

Identification of a novel 4.6-kb genomic deletion in presenilin-1 gene which results in exclusion of exon 9 in a Finnish early onset Alzheimer's disease family: an Alu core sequence-stimulated recombination?

Published in:

European Journal of Human Genetics, 2000, v. 8, n. 4, p. 259, doi. 10.1038/sj.ejhg.5200423

By:

Hiltunen, Mikko;
Helisalmi, Seppo;
Mannermaa, Arto;
Alafuzoff, Irina;
Koivisto, Anne Maria;
Lehtovirta, Maarit;
Pirskanen, Mia;
Sulkava, Raimo;
Verkkoniemi, Auli;
Soininen, Hilkka

Publication type:

Article

Evaluation of polymorphisms in the presenilin-1 gene and the butyrylcholinesterase gene as risk factors in sporadic Alzheimer's disease.

Published in:

European Journal of Human Genetics, 1999, v. 7, n. 6, p. 659, doi. 10.1038/sj.ejhg.5200351

By:

Tilley, Louise;
Morgan, Kevin;
Grainger, Joe;
Marsters, Peter;
Morgan, Linda;
Lowe, James;
Xuereb, John;
Wischik, Charles;
Harrington, Charles;
Kalsheker, Noor

Publication type:

Article

F175S Change and a Novel Polymorphism in Presenilin-1 Gene in Late-Onset Familial Alzheimer’s Disease.

Published in:

European Neurology, 2002, v. 47, n. 4, p. 209, doi. 10.1159/000057901

By:

Colacicco;
Panza;
Basile;
Solfrizzi;
Capurso;
D’Introno;
Torres;
Capurso;
Cozza;
Flora;
Capurso

Publication type:

Article

A study of long-term potentiation in transgenicmice over-expressing mutant forms of bothamyloid precursor protein and presenilin-1.

Published in:

Molecular Brain, 2010, v. 3, p. 21, doi. 10.1186/1756-6606-3-21

By:

Fitzjohn, Stephen M.;
Kuenzi, Frederick;
Morton, Robin A.;
Rosahl, Thomas W.;
Lewis, Huw;
Smith, David;
Seabrook, Guy R.;
Collingridge, Graham L.

Publication type:

Article

Presenilins and the γ-secretase: still a complex problem.

Published in:

Molecular Brain, 2010, v. 3, p. 7, doi. 10.1186/1756-6606-3-7

By:

Small, David H.;
Klaver, David W.;
Foa, Lisa

Publication type:

Article

Corrigendum.

Published in:: 2009
Publication type:: Erratum

A novel presenilin 2 mutation (V393M) in early-onset dementia with profound language impairment.

Published in:

European Journal of Neurology, 2008, v. 15, n. 10, p. 1135, doi. 10.1111/j.1468-1331.2008.02256.x

By:

Lindquist, S. G.;
Hasholt, L.;
Bahl, J. M. C.;
Heegaard, N. H. H.;
Andersen, B. B.;
Nørremølle, A.;
Stokholm, J.;
Schwartz, M.;
Batbayli, M.;
Laursen, H.;
Pardossi-Piquard, R.;
Chen, F.;
St George-Hyslop, P.;
Waldemar, G.;
Nielsen, J. E.

Publication type:

Article

A novel presenilin 1 mutation (V261L) associated with presenile Alzheimer’s disease and spastic paraparesis.

Published in:

European Journal of Neurology, 2008, v. 15, n. 9, p. 991, doi. 10.1111/j.1468-1331.2008.02230.x

By:

Jiménez Caballero, P. E.;
de Diego Boguna, C.;
Martin Correa, E.;
Serviá Candela, M.;
Marsal Alonso, C.

Publication type:

Article

A novel mutation in the PSEN1 gene (L286P) associated with familial early-onset dementia of Alzheimer type and lobar haematomas.

Published in:

European Journal of Neurology, 2007, v. 14, n. 12, p. 1409, doi. 10.1111/j.1468-1331.2007.01988.x

By:

Sánchez-Valle, R.;
Llad, A.;
Ezquerra, M.;
Rey, M. J.;
Rami, L.;
Molinuevo, J. L.

Publication type:

Article

Presenilin immunoreactivity in Alzheimer's disease.

Published in:

European Journal of Neurology, 2005, v. 12, n. 9, p. 700, doi. 10.1111/j.1468-1331.2005.01050.x

By:

Panegyres, P. K.;
Toufexis, K.

Publication type:

Article

New V272A presenilin 1 mutation with very early onset subcortical dementia and parkinsonism.

Published in:

European Journal of Neurology, 2004, v. 11, n. 10, p. 663, doi. 10.1111/j.1468-1331.2004.00865.x

By:

Jimenez-Escrig, A.;
Rabano, A.;
Guerrero, C.;
Simon, J.;
Barquero, M. S.;
Güell, I.;
Ginestal, R. C.;
Montero, T.;
Orensanz, L.

Publication type:

Article

A novel mutation (Thr116Ile) in the presenilin 1 gene in a patient with early-onset Alzheimer's disease.

Published in:

European Journal of Neurology, 2004, v. 11, n. 8, p. 521, doi. 10.1111/j.1468-1331.2004.00828.x

By:

La Bella, V.;
Liguori, M.;
Cittadella, R.;
Settipani, N.;
Piccoli, T.;
Manna, I.;
Quattrone, A.;
Piccoli, F.

Publication type:

Article

Elevated cellular cholesterol in Familial Alzheimer’s presenilin 1 mutation is associated with lipid raft localization of β-amyloid precursor protein.

Published in:

PLoS ONE, 2019, v. 14, n. 1, p. 1, doi. 10.1371/journal.pone.0210535

By:

Cho, Yoon Young;
Kwon, Oh-Hoon;
Park, Myoung Kyu;
Kim, Tae-Wan;
Chung, Sungkwon

Publication type:

Article

Presenilin1 regulates Th1 and Th17 effector responses but is not required for experimental autoimmune encephalomyelitis.

Published in:

PLoS ONE, 2018, v. 13, n. 8, p. 1, doi. 10.1371/journal.pone.0200752

By:

Cummings, Matthew;
Arumanayagam, Anitha Christy Sigamani;
Zhao, Picheng;
Kannanganat, Sunil;
Stuve, Olaf;
Karandikar, Nitin J.;
Eagar, Todd N.

Publication type:

Article

Integration of bioinformatics and imaging informatics for identifying rare PSEN1 variants in Alzheimer's disease.

Published in:

BMC Medical Genomics, 2016, v. 9, p. 11, doi. 10.1186/s12920-016-0190-9

By:

Kwangsik Nho;
Horgusluoglu, Emrin;
Sungeun Kim;
Risacher, Shannon L.;
Dokyoon Kim;
Foroud, Tatiana;
Aisen, Paul S.;
Petersen, Ronald C.;
Jack Jr., Clifford R.;
Shaw, Leslie M.;
Trojanowski, John Q.;
Weiner, Michael W.;
Green, Robert C.;
Toga, Arthur W.;
Saykin, Andrew J.

Publication type:

Article

MicroRNA-29b Modulates β-Secretase Activity in SH-SY5Y Cell Line and Diabetic Mouse Brain.

Published in:

Cellular & Molecular Neurobiology, 2020, v. 40, n. 8, p. 1367, doi. 10.1007/s10571-020-00823-4

By:

Jash, Kavya;
Gondaliya, Piyush;
Sunkaria, Aditya;
Kalia, Kiran

Publication type:

Article

Quantitative Proteomic Analysis of Mitochondria in Aging PS-1 Transgenic Mice.

Published in:

Cellular & Molecular Neurobiology, 2009, v. 29, n. 5, p. 649, doi. 10.1007/s10571-009-9359-5

By:

You-Jun Fu;
Shuling Xiong

Publication type:

Article

Hyperphosphorylation and Accumulation of Neurofilament Proteins in Transgenic Mice with Alzheimer Presenilin 1 Mutation.

Published in:

Cellular & Molecular Neurobiology, 2009, v. 29, n. 4, p. 497, doi. 10.1007/s10571-008-9341-7

By:

Xifei Yang;
Ying Yang;
Yougen Luo;
Geng Li;
Jianzhi Wang;
Edward Yang

Publication type:

Article

Age and Sex Dependent Alteration in Presenilin Expression in Mouse Cerebral Cortex.

Published in:

Cellular & Molecular Neurobiology, 2007, v. 27, n. 8, p. 1059, doi. 10.1007/s10571-007-9214-5

By:

Mahendra Thakur;
Soumi Ghosh

Publication type:

Article

Proteases at work: cues for understanding neural development and degeneration.

Published in:

Frontiers in Molecular Neuroscience, 2015, v. 8, p. 1, doi. 10.3389/fnmol.2015.00013

By:

Saftig, Paul;
Bovolenta, Paola

Publication type:

Article

Neuropathology and biochemistry of early onset familial Alzheimer’s disease caused by presenilin-1 missense mutation Thr116Asn.

Published in:

Journal of Neural Transmission, 2018, v. 125, n. 6, p. 965, doi. 10.1007/s00702-018-1850-z

By:

Sutovsky, Stanislav;
Smolek, Tomas;
Turcani, Peter;
Petrovic, Robert;
Brandoburova, Petra;
Jadhav, Santosh;
Novak, Petr;
Attems, Johannes;
Zilka, Norbert

Publication type:

Article

Amyloid β oligomers (AβOs) in Alzheimer's disease.

Published in:

Journal of Neural Transmission, 2018, v. 125, n. 2, p. 177, doi. 10.1007/s00702-017-1820-x

By:

Mroczko, Barbara;
Groblewska, Magdalena;
Litman-Zawadzka, Ala;
Kornhuber, Johannes;
Lewczuk, Piotr

Publication type:

Article

Early psychiatrics symptoms in familial Alzheimer's disease with presenilin 1 mutation (I83T).

Published in:

Journal of Neural Transmission, 2016, v. 123, n. 4, p. 451, doi. 10.1007/s00702-015-1498-x

By:

Fray, Saloua;
Ali, Nadia;
Rassas, Afef;
Kechaou, Meriem;
Oudiaa, Nouria;
Cherif, Aroua;
Echebbi, Slim;
Messaoud, Taieb;
Belal, Samir

Publication type:

Article

No association between an intronic polymorphism in the presenilin-1 gene and Alzheimer disease in a Tunisian population.

Published in:

Journal of Neural Transmission, 2013, v. 120, n. 9, p. 1355, doi. 10.1007/s00702-013-0985-1

By:

Rassas, Afef;
Fredj, Sondess;
Khiari, Hela;
Sahnoun, Safa;
Bibi, Amina;
Siala, Hajer;
Mrabet, Amel;
Messaoud, Taieb

Publication type:

Article

Alzheimer disease-related presenilin-1 variants exert distinct effects on monoamine oxidase-A activity in vitro.

Published in:

Journal of Neural Transmission, 2011, v. 118, n. 7, p. 987, doi. 10.1007/s00702-011-0616-7

By:

Pennington, Paul;
Wei, Zelan;
Rui, Lewei;
Doig, Jennifer;
Graham, Brett;
Kuski, Kelly;
Gabriel, Geraldine;
Mousseau, Darrell

Publication type:

Article

Two polymorphisms of presenilin-2 gene ( PSEN2) 5′ regulatory region are not associated with Alzheimer’s disease (AD) in the Polish population.

Published in:

Journal of Neural Transmission, 2008, v. 115, n. 1, p. 85, doi. 10.1007/s00702-007-0846-x

By:

Gacia, M.;
Safranow, K.;
Gabryelewicz, T.;
Styczyńska, M.;
Pepłońska, B.;
Dziedziejko, V.;
Jakubowska, K.;
Chlubek, D.;
Żekanowski, C.;
Barcikowska, M.

Publication type:

Article

The -22c/t polymorphism in presenilin 1 gene is not connected with late-onset and early-onset familial Alzheimer’s disease in Poland.

Published in:

Journal of Neural Transmission, 2005, v. 112, n. 6, p. 839, doi. 10.1007/s00702-004-0218-8

By:

Zekanowski, C.;
Religa, D.;
Safranow, K.;
Maruszak, A.;
Dziedziejko, V.;
Styczyńska, M.;
Gacia, M.;
Golan, M.;
Peplońska, B.;
Chlubek, D.;
Kuźnicki, J.;
Barcikowska, M.

Publication type:

Article

Evidence of beta amyloid independent small vessel disease in familial Alzheimer's disease.

Published in:

Brain Pathology, 2022, v. 32, n. 6, p. 1, doi. 10.1111/bpa.13097

By:

Littau, Jessica Lisa;
Velilla, Lina;
Hase, Yoshiki;
Villalba‐Moreno, Nelson David;
Hagel, Christian;
Drexler, Dagmar;
Osorio Restrepo, Santiago;
Villegas, Andres;
Lopera, Francisco;
Vargas, Sergio;
Glatzel, Markus;
Krasemann, Susanne;
Quiroz, Yakeel T.;
Arboleda‐Velasquez, Joseph F.;
Kalaria, Rajesh;
Sepulveda‐Falla, Diego

Publication type:

Article

Familial Dementia With Frontotemporal Features Associated With M146V Presenilin-1 Mutation.

Published in:

Brain Pathology, 2013, v. 23, n. 5, p. 595, doi. 10.1111/bpa.12051

By:

Riudavets, Miguel A.;
Bartoloni, Leonardo;
Troncoso, Juan C.;
Pletnikova, Olga;
St. George‐Hyslop, Peter;
Schultz, Marcelo;
Sevlever, Gustavo;
Allegri, Ricardo F.

Publication type:

Article