Works matching AU McDonnell, P. A.


Results: 141
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    Pharmacokinetic and pharmacodynamic analysis of fulvestrant in preclinical models of breast cancer to assess the importance of its estrogen receptor-α degrader activity in antitumor efficacy.

    Published in:
    Breast Cancer Research & Treatment, 2020, v. 179, n. 1, p. 67, doi. 10.1007/s10549-019-05454-y
    By:
    • Wardell, Suzanne E.;
    • Yllanes, Alexander P.;
    • Chao, Christina A.;
    • Bae, Yeeun;
    • Andreano, Kaitlyn J.;
    • Desautels, Taylor K.;
    • Heetderks, Kendall A.;
    • Blitzer, Jeremy T.;
    • Norris, John D.;
    • McDonnell, Donald P.
    Publication type:
    Article
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    PIK3CA mutations enable targeting of a breast tumor dependency through mTOR-mediated MCL-1 translation.

    Published in:
    Science Translational Medicine, 2016, v. 8, n. 369, p. 1, doi. 10.1126/scitranslmed.aae0348
    By:
    • Anderson, Grace R.;
    • Wardell, Suzanne E.;
    • Cakir, Merve;
    • Crawford, Lorin;
    • Leeds, Jim C.;
    • Nussbaum, Daniel P.;
    • Shankar, Pallavi S.;
    • Soderquist, Ryan S.;
    • Stein, Elizabeth M.;
    • Tingley, Jennifer P.;
    • Winter, Peter S.;
    • Zieser-Misenheimer, Elizabeth K.;
    • Alley, Holly M.;
    • Yllanes, Alexander;
    • Haney, Victoria;
    • Blackwell, Kimberly L.;
    • McCall, Shannon J.;
    • McDonnell, Donald P.;
    • Wood, Kris C.
    Publication type:
    Article
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    Multimodal Regulation of E2F1 Gene Expression by Progestins.

    Published in:
    Molecular & Cellular Biology, 2010, v. 30, n. 8, p. 1, doi. 10.1128/MCB.01060-09
    By:
    • Wade, Hilary E.;
    • Kobayashi, Sakiko;
    • Eaton, Matthew L.;
    • Jansen, Michelle S.;
    • Lobenhofer, Edward K.;
    • Lupien, Mathieu;
    • Geistlinger, Timothy R.;
    • Wencheng Zhu;
    • Nevins, Joseph R.;
    • Brown, Myles;
    • Otteson, Deborah C.;
    • McDonnell, Donald P.
    Publication type:
    Article
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    BRCA1 expression is not directly responsive to estrogen.

    Published in:
    Oncogene, 1997, v. 14, n. 1, p. 115, doi. 10.1038/sj.onc.1200808
    By:
    • Marks, Jeffery R;
    • Huper, Gudrun;
    • Vaughn, James P;
    • Davis, Penelope L;
    • Norris, John;
    • McDonnell, Donald P;
    • Wiseman, Roger W;
    • Futreal, Andrew;
    • Iglehart, J Dirk
    Publication type:
    Article
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    Slow Particle Remineralization, Rather Than Suppressed Disaggregation, Drives Efficient Flux Transfer Through the Eastern Tropical North Pacific Oxygen Deficient Zone.

    Published in:
    Global Biogeochemical Cycles, 2022, v. 36, n. 1, p. 1, doi. 10.1029/2021GB007080
    By:
    • Cram, Jacob A.;
    • Fuchsman, Clara A.;
    • Duffy, Megan E.;
    • Pretty, Jessica L.;
    • Lekanoff, Rachel M.;
    • Neibauer, Jacquelyn A.;
    • Leung, Shirley W.;
    • Huebert, Klaus B.;
    • Weber, Thomas S.;
    • Bianchi, Daniele;
    • Evans, Natalya;
    • Devol, Allan H.;
    • Keil, Richard G.;
    • McDonnell, Andrew M. P.
    Publication type:
    Article
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    Synthetic LXXLL peptide antagonize 1,25-dihydroxyvitamin D.

    Published in:
    Journal of Cellular Biochemistry, 2003, v. 88, n. 2, p. 252, doi. 10.1002/jcb.10336
    By:
    • Pike, J. Wesley;
    • Pathrose, Peterman;
    • Barmina, Olga;
    • Chang, Ching-Yi;
    • McDonnell, Donald P.;
    • Yamamoto, Hironori;
    • Shevde, Nirupama K.
    Publication type:
    Article
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    Modulation of human nuclear receptor LRH-1 activity by phospholipids and SHP.

    Published in:
    Nature Structural & Molecular Biology, 2005, v. 12, n. 4, p. 357, doi. 10.1038/nsmb910
    By:
    • Ortlund, Eric A;
    • Lee, Yoonkwang;
    • Solomon, Isaac H;
    • Hager, Janet M;
    • Safi, Rachid;
    • Choi, Yunhee;
    • Guan, Ziqiang;
    • Tripathy, Ashutosh;
    • Raetz, Christian R H;
    • McDonnell, Donald P;
    • Moore, David D;
    • Redinbo, Matthew R
    Publication type:
    Article
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    Thyroid hormone receptor and ERRα coordinately regulate mitochondrial fission, mitophagy, biogenesis, and function.

    Published in:
    Science Signaling, 2018, v. 11, n. 536, p. 1, doi. 10.1126/scisignal.aam5855
    By:
    • Singh, Brijesh K.;
    • Sinha, Rohit A.;
    • Tripathi, Madhulika;
    • Mendoza, Arturo;
    • Ohba, Kenji;
    • Sy, Jann A. C.;
    • Xie, Sherwin Y.;
    • Zhou, Jin;
    • Ho, Jia Pei;
    • Chang, Ching-yi;
    • Wu, Yajun;
    • Giguère, Vincent;
    • Bay, Boon-Huat;
    • Vanacker, Jean-Marc;
    • Ghosh, Sujoy;
    • Gauthier, Karine;
    • Hollenberg, Anthony N.;
    • McDonnell, Donald P.;
    • Yen, Paul M.
    Publication type:
    Article
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    Systematic identification of signaling pathways with potential to confer anticancer drug resistance.

    Published in:
    Science Signaling, 2014, v. 7, n. 357, p. 1, doi. 10.1126/scisignal.aaa1877
    By:
    • Martz, Colin A.;
    • Ottina, Kathleen A.;
    • Singleton, Katherine R.;
    • Jasper, Jeff S.;
    • Wardell, Suzanne E.;
    • Peraza-Penton, Ashley;
    • Anderson, Grace R.;
    • Winter, Peter S.;
    • Tim Wang;
    • Alley, Holly M.;
    • Kwong, Lawrence N.;
    • Cooper, Zachary A.;
    • Tetzlaff, Michael;
    • Pei-Ling Chen;
    • Rathmell, Jeffrey C.;
    • Flaherty, Keith T.;
    • Wargo, Jennifer A.;
    • McDonnell, Donald P.;
    • Sabatini, David M.;
    • Wood, Kris C.
    Publication type:
    Article
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