Works matching DE "EXENDINS"

Results: 133

Exendin‐4 from Heloderma suspectum venom: From discovery to its latest application as type II diabetes combatant.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2019, v. 124, n. 5, p. 513, doi. 10.1111/bcpt.13169

By:

Yap, Michelle Khai Khun;
Misuan, Nurhamimah

Publication type:

Article

Exendin-4 Improves Nonalcoholic Fatty Liver Disease by Regulating Glucose Transporter 4 Expression in ob/ob Mice.

Published in:

Korean Journal of Physiology & Pharmacology, 2014, v. 18, n. 4, p. 333, doi. 10.4196/kjpp.2014.18.4.333

By:

Seok Kim;
Jaehoon Jung;
Hwajin Kim;
Rok Won Heo;
Chin-ok Yi;
Jung Eun Lee;
Byeong Tak Jeon;
Won-Ho Kim;
Jong Ryeal Hahm;
Gu Seob Roh

Publication type:

Article

Exendin-4 ameliorates cardiac ischemia/reperfusion injury via caveolae and caveolins-3.

Published in:

Cardiovascular Diabetology, 2014, v. 13, n. 1, p. 1, doi. 10.1186/s12933-014-0132-9

By:

Tsutsumi, Yasuo M.;
Tsutsumi, Rie;
Hamaguchi, Eisuke;
Sakai, Yoko;
Kasai, Asuka;
Ishikawa, Yoshihiro;
Yokoyama, Utako;
Tanaka, Katsuya

Publication type:

Article

Oral delivery of bioencapsulated exendin-4 expressed in chloroplasts lowers blood glucose level in mice and stimulates insulin secretion in beta- TC6 cells.

Published in:

Plant Biotechnology Journal, 2013, v. 11, n. 1, p. 77, doi. 10.1111/pbi.12008

By:

Kwon, Kwang‐Chul;
Nityanandam, Ramya;
New, James S.;
Daniell, Henry

Publication type:

Article

The Effect of Feeding Behavior on Hypothalamus in Obese Type 2 Diabetic Rats with Glucagon-like Peptide-1 Receptor Agonist Intervention.

Published in:

Obesity Facts: The European Journal of Obesity, 2018, v. 11, n. 3, p. 181, doi. 10.1159/000486316

By:

Lu, Ke;
Chen, Xiaoyan;
Yan, Jianhua;
Li, Xinchun;
Huang, Chen;
Wan, Qi;
Deng, Xuelian;
Zou, Qiao

Publication type:

Article

Effects of exendin-4, a glucagon like peptide-1 receptor agonist, on neutrophil count and inflammatory cytokines in a rat model of endotoxemia.

Published in:

Journal of Inflammation Research, 2015, v. 8, p. 129, doi. 10.2147/JIR.S84993

By:

Yanay, Ofer;
Bailey, Adam L.;
Kernan, Kelly;
Zimmerman, Jerry J.;
Osborne, William R.

Publication type:

Article

Evaluation of <sup>¹¹¹</sup>In-Labelled Exendin-4 Derivatives Containing Different Meprin β-Specific Cleavable Linkers.

Published in:

PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0123443

By:

Jodal, Andreas;
Pape, Fabienne;
Becker-Pauly, Christoph;
Maas, Ole;
Schibli, Roger;
Béhé, Martin

Publication type:

Article

Correction: In Vitro Metabolic Stability of Exendin-4: Pharmacokinetics and Identification of Cleavage Products.

Published in:

PLoS ONE, 2015, v. 10, n. 4, p. 1, doi. 10.1371/journal.pone.0125296

By:

null, null

Publication type:

Article

The Effects of Exendin-4 Treatment on Graft Failure: An Animal Study Using a Novel Re-Vascularized Minimal Human Islet Transplant Model.

Published in:

PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0121204

By:

Sahraoui, Afaf;
Winzell, Maria Sörhede;
Gorman, Tracy;
Smith, Dave M.;
Skrtic, Stanko;
Hoeyem, Merete;
Abadpour, Shadab;
Johansson, Lars;
Korsgren, Olle;
Foss, Aksel;
Scholz, Hanne

Publication type:

Article

In Vitro Metabolic Stability of Exendin-4: Pharmacokinetics and Identification of Cleavage Products.

Published in:

PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0116805

By:

Liao, Sha;
Liang, Yuanjun;
Zhang, Zhiwei;
Li, Jinglai;
Wang, Juan;
Wang, Xiaoying;
Dou, Guifang;
Zhang, Zhenqing;
Liu, Keliang

Publication type:

Article

Glucagon-Like Peptide-1 Receptor Ligand Interactions: Structural Cross Talk between Ligands and the Extracellular Domain.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0105683

By:

West, Graham M.;
Willard, Francis S.;
Sloop, Kyle W.;
Showalter, Aaron D.;
Pascal, Bruce D.;
Griffin, Patrick R.

Publication type:

Article

Exendin-4 Reduces Ischemic Brain Injury in Normal and Aged Type 2 Diabetic Mice and Promotes Microglial M2 Polarization.

Published in:

PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0103114

By:

Darsalia, Vladimer;
Hua, Sansan;
Larsson, Martin;
Mallard, Carina;
Nathanson, David;
Nyström, Thomas;
Sjöholm, Åke;
Johansson, Maria E.;
Patrone, Cesare

Publication type:

Article

Exendin-4 Pretreated Adipose Derived Stem Cells Are Resistant to Oxidative Stress and Improve Cardiac Performance via Enhanced Adhesion in the Infarcted Heart.

Published in:

PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0099756

By:

Liu, Jianfeng;
Wang, Haibin;
Wang, Yan;
Yin, Yujing;
Wang, Liman;
Liu, Zhiqiang;
Yang, Junjie;
Chen, Yundai;
Wang, Changyong

Publication type:

Article

Correction: Neonatal Exendin-4 Reduces Growth, Fat Deposition and Glucose Tolerance during Treatment in the Intrauterine Growth-Restricted Lamb.

Published in:: PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0095944
Publication type:: Article

Exendin-4 Ameliorates Traumatic Brain Injury-Induced Cognitive Impairment in Rats.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0082016

By:

Eakin, Katharine;
Li, Yazhou;
Chiang, Yung-Hsiao;
Hoffer, Barry J.;
Rosenheim, Hilary;
Greig, Nigel H.;
Miller, Jonathan P.

Publication type:

Article

Indirect Effects of Glucagon-Like Peptide-1 Receptor Agonist Exendin-4 on the Peripheral Circadian Clocks in Mice.

Published in:

PLoS ONE, 2013, v. 8, n. 11, p. 1, doi. 10.1371/journal.pone.0081119

By:

Ando, Hitoshi;
Ushijima, Kentarou;
Fujimura, Akio

Publication type:

Article

The Glucagon-Like Peptide 1 Analogue Exendin-4 Attenuates the Nicotine-Induced Locomotor Stimulation, Accumbal Dopamine Release, Conditioned Place Preference as well as the Expression of Locomotor Sensitization in Mice.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077284

By:

Egecioglu, Emil;
Engel, Jörgen A.;
Jerlhag, Elisabet

Publication type:

Article

Exendin-4 Protects Mitochondria from Reactive Oxygen Species Induced Apoptosis in Pancreatic Beta Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0076172

By:

Li, Zhen;
Zhou, Zhiguang;
Huang, Gan;
Hu, Fang;
Xiang, Yufei;
He, Lining

Publication type:

Article

Exendin-4 Induces Cell Adhesion and Differentiation and Counteracts the Invasive Potential of Human Neuroblastoma Cells.

Published in:

PLoS ONE, 2013, v. 8, n. 8, p. 1, doi. 10.1371/journal.pone.0071716

By:

Luciani, Paola;
Deledda, Cristiana;
Benvenuti, Susanna;
Squecco, Roberta;
Cellai, Ilaria;
Fibbi, Benedetta;
Marone, Ilaria Maddalena;
Giuliani, Corinna;
Modi, Giulia;
Francini, Fabio;
Vannelli, Gabriella Barbara;
Peri, Alessandro

Publication type:

Article

The Glucagon-Like Peptide 1 Analogue, Exendin-4, Attenuates the Rewarding Properties of Psychostimulant Drugs in Mice.

Published in:

PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0069010

By:

Egecioglu, Emil;
Engel, Jörgen A.;
Jerlhag, Elisabet

Publication type:

Article

Neonatal Exendin-4 Reduces Growth, Fat Deposition and Glucose Tolerance during Treatment in the Intrauterine Growth-Restricted Lamb.

Published in:

PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0056553

By:

Gatford, Kathryn L.;
Sulaiman, Siti A.;
Mohammad, Saidatul N. B.;
De Blasio, Miles J.;
Harland, M. Lyn;
Simmons, Rebecca A.;
Owens, Julie A.

Publication type:

Article

Sustained Exendin-4 Secretion through Gene Therapy Targeting Salivary Glands in Two Different Rodent Models of Obesity/Type 2 Diabetes.

Published in:

PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0040074

By:

Di Pasquale, Giovanni;
Dicembrini, Ilaria;
Raimondi, Laura;
Pagano, Claudio;
Egan, Josephine M.;
Cozzi, Andrea;
Cinci, Lorenzo;
Loreto, Andrea;
Manni, Maria E.;
Berretti, Silvia;
Morelli, Annamaria;
Zheng, Changyu;
Michael, Drew G.;
Maggi, Mario;
Vettor, Roberto;
Chiorini, John A.;
Mannucci, Edoardo;
Rotella, Carlo M.

Publication type:

Article

Exendin-4 Improves Steatohepatitis by Increasing Sirt1 Expression in High-Fat Diet-Induced Obese C57BL/6J Mice.

Published in:

PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031394

By:

Jinmi Lee;
Seok-Woo Hong;
Seoung Wan Chae;
Dong Hoon Kim;
Ji Hun Choi;
Ji Cheol Bae;
Se Eun Park;
Eun-Jung Rhee;
Cheol-Young Park;
Ki-Won Oh;
Sung-Woo Park;
Sun-Woo Kim;
Won-Young Lee

Publication type:

Article

Exendin-4 Ameliorates Motor Neuron Degeneration in Cellular and Animal Models of Amyotrophic Lateral Sclerosis.

Published in:

PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0032008

By:

Li, Yazhou;
Chigurupati, Srinivasulu;
Holloway, Harold W.;
Mughal, Mohamed;
Tweedie, David;
Bruestle, Daniel A.;
Mattson, Mark P.;
Wang, Yun;
Harvey, Brandon K.;
Ray, Balmiki;
Lahiri, Debomoy K.;
Greig, Nigel H.

Publication type:

Article

GLP-1 Analogs Reduce Hepatocyte Steatosis and Improve Survival by Enhancing the Unfolded Protein Response and Promoting Macroautophagy.

Published in:

PLoS ONE, 2011, v. 6, n. 9, p. 1, doi. 10.1371/journal.pone.0025269

By:

Sharma, Shvetank;
Mells, Jamie E.;
Ping P. Fu;
Saxena, Neeraj K.;
Anania, Frank A.

Publication type:

Article

Exendin-4 Improves Blood Glucose Control in Both Young and Aging Normal Non-Diabetic Mice, Possible Contribution of Beta Cell Independent Effects.

Published in:

PLoS ONE, 2011, v. 6, n. 5, p. 1, doi. 10.1371/journal.pone.0020443

By:

Rongrong Fan;
Zhanfang Kang;
Lan He;
Juliana Chan;
Gang Xu

Publication type:

Article

Exendin-4 induced glucagon-like peptide-1 receptor activation reverses behavioral impairments of mild traumatic brain injury in mice.

Published in:

Age (0161-9152), 2013, v. 35, n. 5, p. 1621, doi. 10.1007/s11357-012-9464-0

By:

Rachmany, Lital;
Tweedie, David;
Li, Yazhou;
Rubovitch, Vardit;
Holloway, Harold;
Miller, Jonathan;
Hoffer, Barry;
Greig, Nigel;
Pick, Chaim

Publication type:

Article

Amelioration of neurodegenerative changes in cellular and rat models of diabetes-related Alzheimer's disease by exendin-4.

Published in:

Age (0161-9152), 2012, v. 34, n. 5, p. 1211, doi. 10.1007/s11357-011-9303-8

By:

Chen, Song;
Liu, Ai-ran;
An, Feng-mao;
Yao, Wen-bing;
Gao, Xiang-dong

Publication type:

Article

Neurotrophic and neuroprotective properties of exendin-4 in adult rat dorsal root ganglion neurons: involvement of insulin and RhoA.

Published in:

Histochemistry & Cell Biology, 2015, v. 144, n. 3, p. 249, doi. 10.1007/s00418-015-1333-3

By:

Tsukamoto, Masami;
Niimi, Naoko;
Sango, Kazunori;
Takaku, Shizuka;
Kanazawa, Yasushi;
Utsunomiya, Kazunori

Publication type:

Article

Synthesis and Evaluation of Optical and PET GLP-1 Peptide Analogues for GLP-1R Imaging.

Published in:

Molecular Imaging, 2015, v. 14, p. 1, doi. 10.2310/7290.2014.00057

By:

Azad, Babak Behnam;
Rota, Vanessa;
Lihai Yu;
McGirr, Rebecca;
St. Amant, André H.;
Lee, Ting-Yim;
Dhanvantari, Savita;
Luyt, Leonard G.

Publication type:

Article

Exendin-4 attenuates renal tubular injury by decreasing oxidative stress and inflammation in streptozotocin-induced diabetic mice.

Published in:

Growth Factors, 2015, v. 33, n. 5/6, p. 419, doi. 10.3109/08977194.2015.1125349

By:

Sancar-Bas, Serap;
Gezginci-Oktayoglu, Selda;
Bolkent, Sehnaz

Publication type:

Article

Exendin-4 protects INS-1 cells against palmitate-induced apoptosis through the IRE1α-Xbp1 signaling pathway.

Published in:

Experimental & Therapeutic Medicine, 2018, v. 16, n. 2, p. 1029, doi. 10.3892/etm.2018.6240

By:

Jiang, Dongdong;
Wan, Fang

Publication type:

Article

The influence of exendin-4 intervention on non-obese diabetic mouse blood and the pancreatic tissue immune microenvironment.

Published in:

Experimental & Therapeutic Medicine, 2016, v. 12, n. 5, p. 2893, doi. 10.3892/etm.2016.3694

By:

JINSHUI HE;
CHAOWEI LIAN;
YANLING FANG;
JINZHI WU;
HUOWANG ZHOU;
XIAOLING YE

Publication type:

Article

Exendin-4 antagonizes Aβ1-42-induced attenuation of spatial learning and memory ability.

Published in:

Experimental & Therapeutic Medicine, 2016, v. 12, n. 5, p. 2885, doi. 10.3892/etm.2016.3742

By:

XIAOHUI WANG;
LI WANG;
RUIRUI JIANG;
YUNYUN XU;
XUELING ZHAO;
YANG LI

Publication type:

Article

Exendin-4, a glucagon-like peptide-1 receptor agonist, inhibits hyperglycemia-induced apoptosis in myocytes by suppressing receptor for advanced glycation end products expression.

Published in:

Experimental & Therapeutic Medicine, 2014, v. 8, n. 4, p. 1185, doi. 10.3892/etm.2014.1873

By:

BO YI;
XIAORONG HU;
ZHONGYUAN WEN;
TING ZHANG;
YULI CAI

Publication type:

Article

Behavioural profile of exendin-4/naltrexone dose combinations in male rats during tests of palatable food consumption.

Published in:

Psychopharmacology, 2014, v. 231, n. 18, p. 3729, doi. 10.1007/s00213-014-3507-4

By:

Wright, F.;
Rodgers, R.

Publication type:

Article

GLP-1 analog attenuates cocaine reward.

Published in:

Molecular Psychiatry, 2013, v. 18, n. 9, p. 961, doi. 10.1038/mp.2012.141

By:

Graham, D L;
Erreger, K;
Galli, A;
Stanwood, G D

Publication type:

Article

Exendin-4 enhances expression of Neurod1 and Glut2 in insulin-producing cells derived from mouse embryonic stem cells.

Published in:

2016

By:

Qiaoshi Zhao;
Yuzhi Yang;
Jing Hu;
Zhiyan Shan;
Yanshuang Wu;
Lei Lei;
Zhao, Qiaoshi;
Yang, Yuzhi;
Hu, Jing;
Shan, Zhiyan;
Wu, Yanshuang;
Lei, Lei

Publication type:

journal article

The Glucagon-Like Peptide 1 (GLP-1) Analogue, Exendin-4, Decreases the Rewarding Value of Food: A New Role for Mesolimbic GLP-1 Receptors.

Published in:

Journal of Neuroscience, 2012, v. 32, n. 14, p. 4812, doi. 10.1523/JNEUROSCI.6326-11.2012

By:

Dickson, Suzanne L.;
Shirazi, Rozita H.;
Hansson, Caroline;
Bergquist, Filip;
Nissbrandt, Hans;
Skibicka, Karolina P.

Publication type:

Article

Conjugation to a cell-penetrating peptide drives the tumour accumulation of the GLP1R antagonist exendin(9-39).

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2023, v. 50, n. 4, p. 996, doi. 10.1007/s00259-022-06041-y

By:

Collado Camps, Estel;
van Lith, Sanne A. M.;
Kip, Annemarie;
Frielink, Cathelijne;
Joosten, Lieke;
Brock, Roland;
Gotthardt, Martin

Publication type:

Article

Exendin-4 Induces Bone Marrow Stromal Cells Migration Through Bone Marrow-Derived Macrophages Polarization via PKA-STAT3 Signaling Pathway.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2017, v. 44, n. 5, p. 1696, doi. 10.1159/000485776

By:

Wang, Ning;
Gao, Jian;
Jia, Min;
Ma, Xue;
Lei, Zhanxiang;
Da, Fei;
Yan, Fei;
Zhang, Huinan;
Zhou, Ying;
Li, Mingkai;
He, Gonghao;
Meng, Jingru;
Luo, Xiaoxing

Publication type:

Article

Exendin-4 Promotes Beta Cell Proliferation via PI3k/Akt Signalling Pathway.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2015, v. 35, n. 6, p. 2223, doi. 10.1159/000374027

By:

Wang, Chaoxun;
Chen, Xiaopan;
Ding, Xiaoying;
He, Yanju;
Gu, Chengying;
Zhou, Ligang

Publication type:

Article

Exendin-4 Alleviates High Glucose-Induced Rat Mesangial Cell Dysfunction through the AMPK Pathway.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2014, v. 33, n. 2, p. 423, doi. 10.1159/000358623

By:

Xu, Wen-Wei;
Guan, Mei-Ping;
Zheng, Zong-Ji;
Gao, Fang;
Zeng, Yan-Mei;
Qin, Yan;
Xue, Yao-Ming

Publication type:

Article

Inhibition of the Expression of TGF-β1 and CTGF in Human Mesangial Cells byExendin-4, a Glucagon-like Peptide-1Receptor Agonist.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2012, v. 30, n. 3, p. 749, doi. 10.1159/000341454

By:

Li, Wenbin;
Cui, Meiyu;
Wei, Yong;
Kong, Xianglei;
Tang, Lijun;
Xu, Dongmei

Publication type:

Article

Preliminary evaluation of [ F]AlF-NOTA-MAL-Cys -exendin-4 in insulinoma with PET.

Published in:

Journal of Drug Targeting, 2015, v. 23, n. 9, p. 813, doi. 10.3109/1061186X.2015.1020808

By:

Xu, Qing;
Zhu, Chen;
Xu, Yuping;
Pan, Donghui;
Liu, Ping;
Yang, Runlin;
Wang, Lizhen;
Chen, Fei;
Sun, Xinchen;
Luo, Shineng;
Yang, Min

Publication type:

Article

Effects of Exendin-4 on Male Reproductive Parameters of D-Galactose Induced Aging Mouse Model.

Published in:

World Journal of Men's Health, 2014, v. 32, n. 3, p. 176, doi. 10.5534/wjmh.2014.32.3.176

By:

Akram Ahangarpour;
Oroojan, Ali Akbar;
Hamid Heidari

Publication type:

Article

Effects of Exendin-4 on bone marrow mesenchymal stem cell proliferation, migration and apoptosis in vitro.

Published in:

Scientific Reports, 2015, p. 12898, doi. 10.1038/srep12898

By:

Zhou, Hao;
Li, Dandan;
Shi, Chen;
Xin, Ting;
Yang, Junjie;
Zhou, Ying;
Hu, Shunyin;
Tian, Feng;
Wang, Jing;
Chen, Yundai

Publication type:

Article

Xenotransplantation of exendin-4 gene transduced pancreatic islets using multi-component (alginate, poly-L-lysine, and polyethylene glycol) microcapsules for the treatment of type 1 diabetes mellitus.

Published in:

Journal of Biomaterials Science -- Polymer Edition, 2013, v. 24, n. 17, p. 2045, doi. 10.1080/09205063.2013.823071

By:

Park, Jun-Beom;
Jeong, Jee-Heon;
Lee, Minhyung;
Lee, Dong Yun;
Byun, Youngro

Publication type:

Article

Exendin-4, a glucagon-like peptide-1 analogue accelerates healing of chronic gastric ulcer in diabetic rats.

Published in:

PLoS ONE, 2017, v. 12, n. 11, p. 1, doi. 10.1371/journal.pone.0187434

By:

Chen, Yen-Cheng;
Ho, Ching-Chun;
Yi, Chih-Hsun;
Liu, Xiu-Zhu;
Cheng, Tzu-Ting;
Lam, Chen-Fuh

Publication type:

Article

Exendin-4 Upregulates Adiponectin Level in Adipocytes via Sirt1/Foxo-1 Signaling Pathway.

Published in:

PLoS ONE, 2017, v. 12, n. 1, p. 1, doi. 10.1371/journal.pone.0169469

By:

Wang, Anping;
Li, Ting;
An, Ping;
Yan, Wenhua;
Zheng, Hua;
Wang, Baoan;
Mu, Yiming

Publication type:

Article