Works matching AU Lewerenz, Jan

Results: 45

Cerebrospinal Fluid Levels of Prodynorphin‐Derived Peptides are Decreased in Huntington's Disease.

Published in:

Movement Disorders, 2021, v. 36, n. 2, p. 492, doi. 10.1002/mds.28300

By:

Al Shweiki, MHD Rami;
Oeckl, Patrick;
Pachollek, Adrian;
Steinacker, Petra;
Barschke, Peggy;
Halbgebauer, Steffen;
Anderl‐Straub, Sarah;
Lewerenz, Jan;
Ludolph, Albert C.;
Bernhard Landwehrmeyer, Georg;
Otto, Markus

Publication type:

Article

Krankheitsmodifizierende Therapieansätze bei der Huntington-Krankheit: Blicke zurück und Blicke voraus.

Published in:

Der Nervenarzt, 2022, v. 93, n. 2, p. 179, doi. 10.1007/s00115-021-01224-8

By:

Frank, Wiebke;
Lindenberg, Katrin S.;
Mühlbäck, Alzbeta;
Lewerenz, Jan;
Landwehrmeyer, G. Bernhard

Publication type:

Article

Mitochondrial function and energy metabolism in neuronal HT22 cells resistant to oxidative stress.

Published in:

British Journal of Pharmacology, 2014, v. 171, n. 8, p. 2147, doi. 10.1111/bph.12549

By:

Pfeiffer, Annika;
Jaeckel, Martin;
Lewerenz, Jan;
Noack, Rebecca;
Pouya, Alireza;
Schacht, Teresa;
Hoffmann, Christina;
Winter, Jennifer;
Schweiger, Susann;
Schäfer, Michael K E;
Methner, Axel

Publication type:

Article

The flavonoid fisetin attenuates postischemic immune cell infiltration, activation and infarct size after transient cerebral middle artery occlusion in mice.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2012, v. 32, n. 5, p. 835, doi. 10.1038/jcbfm.2011.189

By:

Gelderblom, Mathias;
Leypoldt, Frank;
Lewerenz, Jan;
Birkenmayer, Gabriel;
Orozco, Denise;
Ludewig, Peter;
Thundyil, John;
Arumugam, Thiruma V;
Gerloff, Christian;
Tolosa, Eva;
Maher, Pamela;
Magnus, Tim

Publication type:

Article

Intravenous immunoglobulin as first-line acute treatment in adults with autoimmune encephalitis caused by antibodies to NMDAR, LGI1 and CASPR2.

Published in:

Journal of Neurology, 2025, v. 272, n. 4, p. 1, doi. 10.1007/s00415-025-13032-0

By:

Rittel, Joyce Christin;
Hudasch, Dominica;
Doppler, Kathrin;
Bergh, Florian Then;
Lesser, Martin;
Aktas, Orhan;
Nagel, Michael;
Huttner, Hagen B.;
Rostasy, Kevin;
Tauber, Simone;
Friese, Manuel A.;
Malter, Michael;
Madlener, Marie;
Kraft, Andrea;
Hoffmann, Frank;
Lewerenz, Jan;
Senel, Makbule;
Wickel, Jonathan;
Geis, Christian;
Moser, Andreas

Publication type:

Article

[18F]DPA-714-PET-MRI reveals pronounced innate immunity in human anti-LGI1 and anti-CASPR2 limbic encephalitis.

Published in:

Journal of Neurology, 2024, v. 271, n. 6, p. 3653, doi. 10.1007/s00415-024-12302-7

By:

Roll, Wolfgang;
Bauer, Jan;
Dik, Andre;
Mueller, Christoph;
Backhaus, Philipp;
Räuber, Saskia;
Zinnhardt, Bastian;
Gallus, Marco;
Wimberley, Catriona;
Körtvelyessy, Peter;
Schindler, Philipp;
Stenzel, Werner;
Elger, Christian E.;
Becker, Albert;
Lewerenz, Jan;
Wiendl, Heinz;
Meuth, Sven G.;
Schäfers, Michael;
Melzer, Nico

Publication type:

Article

Different pain phenotypes are associated with anti-Caspr2 autoantibodies.

Published in:

Journal of Neurology, 2024, v. 271, n. 5, p. 2736, doi. 10.1007/s00415-024-12224-4

By:

Greguletz, Patrik;
Plötz, Maria;
Baade-Büttner, Carolin;
Bien, Christian G.;
Eisenhut, Katharina;
Geis, Christian;
Handreka, Robert;
Klausewitz, Jaqueline;
Körtvelyessy, Peter;
Kovac, Stjepana;
Kraft, Andrea;
Lewerenz, Jan;
Malter, Michael;
Nagel, Michael;
von Podewils, Felix;
Prüß, Harald;
Rada, Anna;
Rau, Johanna;
Rauer, Sebastian;
Rößling, Rosa

Publication type:

Article

Cerebrospinal fluid levels of proenkephalin and prodynorphin are differentially altered in Huntington's and Parkinson's disease.

Published in:

Journal of Neurology, 2022, v. 269, n. 9, p. 5136, doi. 10.1007/s00415-022-11187-8

By:

Barschke, Peggy;
Abu-Rumeileh, Samir;
Al Shweiki, M. H. D. Rami;
Barba, Lorenzo;
Paolini Paoletti, Federico;
Oeckl, Patrick;
Steinacker, Petra;
Halbgebauer, Steffen;
Gaetani, Lorenzo;
Lewerenz, Jan;
Ludolph, Albert Christian;
Landwehrmeyer, Georg Bernhard;
Parnetti, Lucilla;
Otto, Markus

Publication type:

Article

Admission diagnoses of patients later diagnosed with autoimmune encephalitis.

Published in:

Journal of Neurology, 2019, v. 266, n. 1, p. 124, doi. 10.1007/s00415-018-9105-3

By:

Baumgartner, Annette;
Rauer, Sebastian;
Hottenrott, Tilman;
Leypoldt, Frank;
Ufer, Friederike;
Hegen, Harald;
Prüss, Harald;
Lewerenz, Jan;
Deisenhammer, Florian;
Stich, Oliver

Publication type:

Article

Identifying ischemic stroke associated with cancer: a multiple model derived from a case-control analysis.

Published in:

Journal of Neurology, 2017, v. 264, n. 4, p. 781, doi. 10.1007/s00415-017-8432-0

By:

Kassubek, Rebecca;
Bullinger, Lars;
Kassubek, Jan;
Dreyhaupt, Jens;
Ludolph, Albert;
Althaus, Katharina;
Lewerenz, Jan

Publication type:

Article

p62, Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects.

Published in:

Autophagy, 2011, v. 7, n. 6, p. 572, doi. 10.4161/auto.7.6.14943

By:

Bartlett, Bryan J.;
Isakson, Pauline;
Lewerenz, Jan;
Sanchez, Heriberto;
Kotzebue, Roxanne W.;
Cumming, Robert;
Harris, Greg L.;
Nezis, Ioannis P.;
Schubert, David;
Simonsen, Anne;
Finley, Kim D.

Publication type:

Article

Mechanismen und Bedeutung der oxidativen Glutamattoxizität.

Published in:

Neuroforum, 2006, v. 12, n. 3, p. 222, doi. 10.1515/nf-2006-0303

By:

Lewerenz, Jan;
Methner, Axel

Publication type:

Article

Genetic predisposition in anti-LGI1 and anti-NMDA receptor encephalitis.

Published in:

2018

By:

Mueller, Stefanie H.;
Färber, Anna;
Prüss, Harald;
Melzer, Nico;
Golombeck, Kristin S.;
Kümpfel, Tania;
Thaler, Franziska;
Elisak, Martin;
Lewerenz, Jan;
Kaufmann, Max;
Sühs, Kurt‐Wolfram;
Ringelstein, Marius;
Kellinghaus, Christoph;
Bien, Christian G.;
Kraft, Andrea;
Zettl, Uwe K.;
Ehrlich, Sven;
Handreka, Robert;
Rostásy, Kevin;
Then Bergh, Florian

Publication type:

journal article

Long latency between GAD-antibody detection and development of limbic encephalitis--a case report.

Published in:

2015

By:

Fauser, Susanne;
Uttner, Ingo;
Ariño, Helena;
Scherbaum, Werner A.;
Saiz, Albert;
Lewerenz, Jan

Publication type:

journal article

CSF Free Light Chains as a Marker of Intrathecal Immunoglobulin Synthesis in Multiple Sclerosis: A Blood-CSF Barrier Related Evaluation in a Large Cohort.

Published in:

Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00641

By:

Senel, Makbule;
Mojib-Yezdani, Fatemeh;
Braisch, Ulrike;
Bachhuber, Franziska;
Lewerenz, Jan;
Ludolph, Albert C.;
Otto, Markus;
Tumani, Hayrettin

Publication type:

Article

Cerebrospinal Fluid Findings in Patients With Autoimmune Encephalitis—A Systematic Analysis.

Published in:

Frontiers in Neurology, 2019, p. 1, doi. 10.3389/fneur.2019.00804

By:

Blinder, Tetyana;
Lewerenz, Jan

Publication type:

Article

Absence of system xc- on immune cells invading the central nervous system alleviates experimental autoimmune encephalitis.

Published in:

2017

By:

Merckx, Ellen;
Albertini, Giulia;
Paterka, Magdalena;
Jensen, Cathy;
Albrecht, Philipp;
Dietrich, Michael;
Van Liefferinge, Joeri;
Bentea, Eduard;
Verbruggen, Lise;
Demuyser, Thomas;
Deneyer, Lauren;
Lewerenz, Jan;
van Loo, Geert;
De Keyser, Jacques;
Sato, Hideyo;
Maher, Pamela;
Methner, Axel;
Massie, Ann

Publication type:

journal article

Decreased IL-8 levels in CSF and serum of AD patients and negative correlation of MMSE and IL-1β.

Published in:

BMC Neurology, 2016, v. 16, p. 1, doi. 10.1186/s12883-016-0707-z

By:

Hesse, Raphael;
Wahler, Anke;
Gummert, Pauline;
Kirschmer, Stefanie;
Otto, Markus;
Tumani, Hayrettin;
Lewerenz, Jan;
Schnack, Cathrin;
von Arnim, Christine A. F.

Publication type:

Article

Regulation of xCT expression and system function in neuronal cells.

Published in:

Amino Acids, 2012, v. 42, n. 1, p. 171, doi. 10.1007/s00726-011-0862-x

By:

Lewerenz, Jan;
Maher, Pamela;
Methner, Axel

Publication type:

Article

Development of an algorithm for identifying paraneoplastic ischemic stroke in association with lung, pancreatic, and colorectal cancer.

Published in:

Therapeutic Advances in Neurological Disorders, 2024, p. 1, doi. 10.1177/17562864241239123

By:

Kassubek, Rebecca;
Winter, Marc-Andre G. R.;
Dreyhaupt, Jens;
Laible, Mona;
Kassubek, Jan;
Ludolph, Albert C.;
Lewerenz, Jan

Publication type:

Article

Development of an algorithm for identifying paraneoplastic ischemic stroke in association with lung, pancreatic, and colorectal cancer.

Published in:

Therapeutic Advances in Neurological Disorders, 2024, v. 17, p. 1, doi. 10.1177/17562864241239123

By:

Kassubek, Rebecca;
Winter, Marc-Andre G. R.;
Dreyhaupt, Jens;
Laible, Mona;
Kassubek, Jan;
Ludolph, Albert C.;
Lewerenz, Jan

Publication type:

Article

Main path and byways: non-vesicular glutamate release by system xc- as an important modifier of glutamatergic neurotransmission.

Published in:

Journal of Neurochemistry, 2015, v. 135, n. 6, p. 1062, doi. 10.1111/jnc.13348

By:

Massie, Ann;
Boillée, Séverine;
Hewett, Sandra;
Knackstedt, Lori;
Lewerenz, Jan

Publication type:

Article

Lactacidosis modulates glutathione metabolism and oxidative glutamate toxicity.

Published in:

Journal of Neurochemistry, 2010, v. 113, n. 2, p. 502, doi. 10.1111/j.1471-4159.2010.06621.x

By:

Lewerenz, Jan;
Dargusch, Richard;
Maher, Pamela

Publication type:

Article

Induction of Nrf2 and xCT are involved in the action of the neuroprotective antibiotic ceftriaxone in vitro.

Published in:

Journal of Neurochemistry, 2009, v. 111, n. 2, p. 332, doi. 10.1111/j.1471-4159.2009.06347.x

By:

Lewerenz, Jan;
Albrecht, Philipp;
Tien, Mai-Ly Tran;
Henke, Nadine;
Karumbayaram, Saravanan;
Kornblum, Harley I.;
Wiedau-Pazos, Martina;
Schubert, Dave;
Maher, Pamela;
Methner, Axel

Publication type:

Article

Nitroxyl exacerbates ischemic cerebral injury and oxidative neurotoxicity.

Published in:

Journal of Neurochemistry, 2009, v. 110, n. 6, p. 1766, doi. 10.1111/j.1471-4159.2009.06266.x

By:

Chi-un Choe;
Lewerenz, Jan;
Fischer, Gerry;
Uliasz, Tracy F.;
Espey, Michael Graham;
Hummel, Friedhelm C.;
King, Stephen Bruce;
Schwedhelm, Edzard;
Böger, Rainer H.;
Gerloff, Christian;
Hewett, Sandra J.;
Magnus, Tim;
Donzelli, Sonia

Publication type:

Article

A novel approach to enhancing cellular glutathione levels.

Published in:

Journal of Neurochemistry, 2008, v. 107, n. 3, p. 690, doi. 10.1111/j.1471-4159.2008.05620.x

By:

Maher, Pamela;
Lewerenz, Jan;
Lozano, Carles;
Torres, Josep Lluís

Publication type:

Article

Lesion of the dorsorostral midbrain sparing the nigrostriatal tract mimics axial rigidity seen in progressive supranuclear palsy.

Published in:

Movement Disorders, 2005, v. 20, n. 8, p. 1071, doi. 10.1002/mds.20484

By:

Lewerenz, Jan;
Zurowski, Bartosz;
Jenicke, Lars;
Bäumer, Tobias;
Lees, Andrew J.;
Münchau, Alexander

Publication type:

Article

Chronic Glutamate Toxicity in Neurodegenerative Diseases--What is the Evidence?

Published in:

Frontiers in Neuroscience, 2015, p. 1, doi. 10.3389/fnins.2015.00469

By:

Lewerenz, Jan;
Maher, Pamela;
Freire, Marco Aurelio M.;
Vickers, James C.

Publication type:

Article

Blood–CSF barrier integrity in amyotrophic lateral sclerosis.

Published in:

Brain: A Journal of Neurology, 2024, v. 147, n. 12, p. 4254, doi. 10.1093/brain/awae144

By:

Klose, Veronika;
Jesse, Sarah;
Lewerenz, Jan;
Kassubek, Jan;
Dorst, Johannes;
Rosenbohm, Angela;
Nagel, Gabriele;
Wernecke, Deborah;
Roselli, Francesco;
Tumani, Hayrettin;
Ludolph, Albert C

Publication type:

Article

Clinical, serological and genetic predictors of response to immunotherapy in anti-IgLON5 disease.

Published in:

Brain: A Journal of Neurology, 2023, v. 146, n. 2, p. 600, doi. 10.1093/brain/awac090

By:

Grüter, Thomas;
Möllers, Franziska E;
Tietz, Anja;
Dargvainiene, Justina;
Melzer, Nico;
Heidbreder, Anna;
Strippel, Christine;
Kraft, Andrea;
Höftberger, Romana;
Schöberl, Florian;
Thaler, Franziska S;
Wickel, Jonathan;
Chung, Ha-Yeun;
Seifert, Frank;
Tschernatsch, Marlene;
Nagel, Michael;
Lewerenz, Jan;
Jarius, Sven;
Wildemann, Brigitte C;
Azevedo, Lucie de

Publication type:

Article

Effects of dimethyl fumarate on neuroprotection and immunomodulation.

Published in:

Journal of Neuroinflammation, 2012, v. 9, n. 1, p. 163, doi. 10.1186/1742-2094-9-163

By:

Albrecht, Philipp;
Bouchachia, Imane;
Goebels, Norbert;
Henke, Nadine;
Hofstetter, Harald H.;
Issberner, Andrea;
Kovacs, Zsuzsa;
Lewerenz, Jan;
Lisak, Dmitrij;
Maher, Pamela;
Mausberg, Anne-Kathrin;
Quasthoff, Kim;
Zimmermann, Corinna;
Hartung, Hans-Peter;
Methner, Axel

Publication type:

Article

Das NF1‐Mikrodeletions‐Syndrom: Die frühzeitige genetische Diagnose erleichtert den Umgang mit einer klinisch definierten Erkrankung.

Published in:

Journal der Deutschen Dermatologischen Gesellschaft, 2022, v. 20, n. 3, p. 273, doi. 10.1111/ddg.14707_g

By:

Kehrer‐Sawatzki, Hildegard;
Bäzner, Ute;
Krämer, Johannes;
Lewerenz, Jan;
Pfeiffer, Christiane

Publication type:

Article

The NF1 microdeletion syndrome: early genetic diagnosis facilitates the management of a clinically defined disease.

Published in:

Journal der Deutschen Dermatologischen Gesellschaft, 2022, v. 20, n. 3, p. 273, doi. 10.1111/ddg.14707

By:

Kehrer‐Sawatzki, Hildegard;
Bäzner, Ute;
Krämer, Johannes;
Lewerenz, Jan;
Pfeiffer, Christiane

Publication type:

Article

Charcot–Marie–Tooth disease CMT4A: GDAP1 increases cellular glutathione and the mitochondrial membrane potential.

Published in:

Human Molecular Genetics, 2012, v. 21, n. 1, p. 150, doi. 10.1093/hmg/ddr450

By:

Noack, Rebecca;
Frede, Svenja;
Albrecht, Philipp;
Henke, Nadine;
Pfeiffer, Annika;
Knoll, Katrin;
Dehmel, Thomas;
Meyer zu Hörste, Gerd;
Stettner, Mark;
Kieseier, Bernd C.;
Summer, Holger;
Golz, Stefan;
Kochanski, Andrzej;
Wiedau-Pazos, Martina;
Arnold, Susanne;
Lewerenz, Jan;
Methner, Axel

Publication type:

Article

Fumaric Acid Esters Stimulate Astrocytic VEGF Expression through HIF-1α and Nrf2.

Published in:

PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0076670

By:

Wiesner, Diana;
Merdian, Irma;
Lewerenz, Jan;
Ludolph, Albert C.;
Dupuis, Luc;
Witting, Anke

Publication type:

Article

Ubiquitination and the proteasome rather than caspase‐3‐mediated C‐terminal cleavage are involved in the EAAT2 degradation by staurosporine‐induced cellular stress.

Published in:

Journal of Neurochemistry, 2021, v. 157, n. 4, p. 1284, doi. 10.1111/jnc.15237

By:

Voss, Timo‐Daniel;
Gerget, Maria;
Linkus, Birgit;
Einem, Bjoern;
Landwehrmeyer, G. Bernhard;
Lewerenz, Jan

Publication type:

Article

Cooperative action of glutamate transporters and cystine/glutamate antiporter system Xc– protects from oxidative glutamate toxicity.

Published in:

Journal of Neurochemistry, 2006, v. 98, n. 3, p. 916, doi. 10.1111/j.1471-4159.2006.03921.x

By:

Lewerenz, Jan;
Klein, Mathias;
Methner, Axel

Publication type:

Article

Activation of stimulatory heterotrimeric G proteins increases glutathione and protects neuronal cells against oxidative stress.

Published in:

Journal of Neurochemistry, 2003, v. 87, n. 2, p. 522, doi. 10.1046/j.1471-4159.2003.02019.x

By:

Lewerenz, Jan;
Letz, Julia;
Methner, Axel

Publication type:

Article

Clinical associations and characteristics of the polyspecific intrathecal immune response in elderly patients with non-multiple sclerosis chronic autoimmune-inflammatory neurological diseases - a retrospective cross-sectional study.

Published in:

Frontiers in Neurology, 2023, p. 1, doi. 10.3389/fneur.2023.1193015

By:

Brauchle, Felix;
Rapp, Daniel;
Senel, Makbule;
Huss, André;
Dreyhaupt, Jens;
Klose, Veronika;
Süße, Marie;
Stürner, Klarissa Hanja;
Leypoldt, Frank;
Tumani, Hayrettin;
Lewerenz, Jan

Publication type:

Article

CSF oligoclonal IgG bands are not associated with ALS progression and prognosis.

Published in:

Frontiers in Neurology, 2023, p. 1, doi. 10.3389/fneur.2023.1170360

By:

Klose, Veronika;
Jesse, Sarah;
Lewerenz, Jan;
Kassubek, Jan;
Dorst, Johannes;
Tumani, Hayrettin;
Ludolph, Albert C.;
Roselli, Francesco

Publication type:

Article

A 64‐Year‐Old Patient With a Mesiotemporal Mass and Symptomatic Epilepsy.

Published in:

Brain Pathology, 2020, v. 30, n. 2, p. 413, doi. 10.1111/bpa.12818

By:

Kuehn, Julia C.;
Scheuerle, Angelika;
Bauer, Jan;
Becker, Albert J.;
Wirtz, Rainer;
Lewerenz, Jan

Publication type:

Article

Induction of Bcl-2 by functional regulation of G-protein coupled receptors protects from oxidative glutamate toxicity by increasing glutathione

Published in:

Free Radical Research, 2006, v. 40, n. 11, p. 1113, doi. 10.1080/10715760600838191

By:

Sahin, Mert;
Saxena, Ambrish;
Joost, Patrick;
Lewerenz, Jan;
Methner, Axel

Publication type:

Article

Tick-Borne Encephalitis: A Differential Pattern of Intrathecal Humoral Immune Response and Inflammatory Cell Composition Compared with Other Viral CNS Infections.

Published in:

Cells (2073-4409), 2020, v. 9, n. 10, p. 2169, doi. 10.3390/cells9102169

By:

Senel, Makbule;
Rapp, Daniel;
Mayer, Benjamin;
Jesse, Sarah;
Süssmuth, Sigurd D.;
Otto, Markus;
Lewerenz, Jan;
Tumani, Hayrettin

Publication type:

Article

Bevacizumab in temozolomide refractory high-grade gliomas: single-centre experience and review of the literature.

Published in:

Therapeutic Advances in Neurological Disorders, 2018, v. 11, p. 1, doi. 10.1177/1756285617753597

By:

Jeck, Jennifer;
Kassubek, Rebecca;
Coburger, Jan;
Edenhofer, Simone;
Schönsteiner, Stefan S.;
Ludolph, Albert C.;
Schmitz, Bernd;
Engelke, Jens;
Mayer-Steinacker, Regine;
Lewerenz, Jan;
Bullinger, Lars

Publication type:

Article

Oxytosis/Ferroptosis-(Re-) Emerging Roles for Oxidative Stress-Dependent Non-apoptotic Cell Death in Diseases of the Central Nervous System.

Published in:

Frontiers in Neuroscience, 2018, p. 1, doi. 10.3389/fnins.2018.00214

By:

Lewerenz, Jan;
Ates, Gamze;
Methner, Axel;
Conrad, Marcus;
Maher, Pamela

Publication type:

Article