Works matching DE "MICROSOMES"

Results: 1148

In vitro evaluation on the antioxidant capacity of triethylchebulate, an aglycone from Terminalia chebula Retz fruit.

Published in:

Indian Journal of Pharmacology, 2011, v. 43, n. 3, p. 320, doi. 10.4103/0253-7613.81508

By:

Xiuping Chen;
Fangyun Sun;
Lifeng Ma;
Jinhua Wang;
Hailin Qin;
Guanhua Du

Publication type:

Article

Morphine Metabolism in Human Skin Microsomes.

Published in:

Skin Pharmacology & Physiology, 2012, v. 25, n. 6, p. 319, doi. 10.1159/000342067

By:

Heilmann, S.;
Küchler, S.;
Schäfer-Korting, M.

Publication type:

Article

Braking Bad: Stopping Translation in Hard Times.

Published in:

PLoS Biology, 2014, v. 12, n. 5, p. 1, doi. 10.1371/journal.pbio.1001867

By:

Roberts, Roland G.

Publication type:

Article

Coupled Motions Direct Electrons along Human Microsomal P450 Chains.

Published in:

PLoS Biology, 2011, v. 9, n. 12, p. 1, doi. 10.1371/journal.pbio.1001222

By:

Pudney, Christopher R.;
Khara, Basile;
Johannissen, Linus O.;
Scrutton, Nigel S.

Publication type:

Article

SRP and NAC: Guiding a Nascent Protein's First Steps.

Published in:

PLoS Biology, 2011, v. 9, n. 7, p. 1, doi. 10.1371/journal.pbio.1001103

By:

Sedwick, Caitlin

Publication type:

Article

Antioxidant activity of methanolic extract of Bombax ceiba.

Published in:

Redox Report, 2009, v. 14, n. 1, p. 41, doi. 10.1179/135100009X392485

By:

Vieira, Tiago O.;
Said, Ataa;
Aboutabl, Elsayed;
Azzam, Mona;
Creczynski-Pasa, Tânia B.

Publication type:

Article

Probucol as a potent inhibitor of oxygen radical-induced lipid peroxidation and DNA damage: in vitro studies.

Published in:

Redox Report, 2004, v. 9, n. 3, p. 167, doi. 10.1179/135100004225005174

By:

Iqbal, Mohammad;
Sharma, Som Datta;
Okada, Shigeru

Publication type:

Article

Inhibition of cytochrome P450 isozymes in rat liver microsomes by polysaccharides derived from Phellinus linteus.

Published in:

Biotechnology Letters, 2003, v. 25, n. 2, p. 167, doi. 10.1023/A:1021935922722

By:

Yun-Hee Shon;
Kyung-Soo Nam

Publication type:

Article

Sanguinarine induces K<sup>+</sup> outflow from yeast cells expressing mammalian sodium pumps.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2001, v. 363, n. 2, p. 203, doi. 10.1007/s002100000355

By:

Scheiner-Bobis, Georgios

Publication type:

Article

In vitro assessment of cytochrome P450 inhibition and induction potential of tanespimycin and its major metabolite, 17-amino-17-demethoxygeldanamycin.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 1, p. 51, doi. 10.1007/s00280-011-1672-2

By:

Gan, Jinping;
Liu-Kreyche, Peggy;
Humphreys, W.

Publication type:

Article

The small-molecule tyrosine kinase inhibitor nilotinib is a potent noncompetitive inhibitor of the SN-38 glucuronidation by human UGT1A1.

Published in:

Cancer Chemotherapy & Pharmacology, 2011, v. 67, n. 1, p. 237, doi. 10.1007/s00280-010-1445-3

By:

Fujita, Ken-ichi;
Sugiyama, Minako;
Akiyama, Yuko;
Ando, Yuichi;
Sasaki, Yasutsuna

Publication type:

Article

In vitro assessment of cytochrome P450 inhibition and induction potential of azacitidine.

Published in:

Cancer Chemotherapy & Pharmacology, 2010, v. 65, n. 5, p. 995, doi. 10.1007/s00280-010-1245-9

By:

Yong Chen;
Liu, Lisa;
Laille, Eric;
Kumar, Gondi;
Surapaneni, Sekhar

Publication type:

Article

Preclinical pharmacokinetics and in vitro metabolism of dasatinib (BMS-354825): a potent oral multi-targeted kinase inhibitor against SRC and BCR-ABL.

Published in:

Cancer Chemotherapy & Pharmacology, 2008, v. 61, n. 3, p. 365, doi. 10.1007/s00280-007-0478-8

By:

Kamath, Amrita V.;
Jian Wang;
Lee, Francis Y.;
Marathe, Punit H.

Publication type:

Article

Comparison of pharmacokinetic and metabolic profiling among gossypol, apogossypol and apogossypol hexaacetate.

Published in:

Cancer Chemotherapy & Pharmacology, 2008, v. 61, n. 1, p. 63, doi. 10.1007/s00280-007-0446-3

By:

Jia, Lee;
Coward, Lori C.;
Kerstner-Wood, Corenna D.;
Cork, Ronda L.;
Gorman, Gregory S.;
Noker, Patricia E.;
Kitada, Shinichi;
Pellecchia, Marrizio;
Reed, John C.

Publication type:

Article

Characterization of two phase I metabolites of bendamustine in human liver microsomes and in cancer patients treated with bendamustine hydrochloride.

Published in:

Cancer Chemotherapy & Pharmacology, 2007, v. 59, n. 6, p. 759, doi. 10.1007/s00280-006-0331-5

By:

Teichert, Jens;
Baumann, Frank;
Qi Chao;
Franklin, Craig;
Bailey, Brandy;
Hennig, Lothar;
Caca, Karel;
Schoppmeyer, Konrad;
Patzak, Ulrich;
Preiss, Rainer

Publication type:

Article

Satraplatin activation by haemoglobin, cytochrome C and liver microsomes in vitro.

Published in:

Cancer Chemotherapy & Pharmacology, 2006, v. 57, n. 4, p. 483, doi. 10.1007/s00280-005-0069-5

By:

Carr, Jocelyn L.;
Tingle, Malcolm D.;
McKeage, Mark J.

Publication type:

Article

Cytochrome P450 isozymes 3A4 and 2B6 are involved in the in vitro human metabolism of thiotepa to TEPA.

Published in:

2002

By:

Jacobson, P. A.;
Green, K.;
Birnbaum, A.;
Remmel, R. P.

Publication type:

journal article

Effects of paclitaxel, cyclophosphamide, ifosfamide, tamoxifen and cyclosporine on the metabolism of methoxymorpholinodoxorubicin in human liver microsomes.

Published in:

2002

By:

Beulz-Riché, Dominique;
Robert, Jacques;
Riché, Christian;
Ratanasavanh, Damrong;
Beulz-Riché, Dominique;
Riché, Christian

Publication type:

journal article

A difference between the rat and mouse in the pharmacokinetic interaction of 5,6-dimethylxanthenone-4-acetic acid with thalidomide.

Published in:

Cancer Chemotherapy & Pharmacology, 2001, v. 47, n. 6, p. 541, doi. 10.1007/s002800100285

By:

Shufeng Zhou;
Kestell, Philip;
Tingle, Malcolm D.;
Lai-Ming Ching;
Paxton, James W.

Publication type:

Article

Reduction of cyclophosphamide bioactivation by thioTEPA: critical sequence-dependency in high-dose chemotherapy regimens.

Published in:

Cancer Chemotherapy & Pharmacology, 2000, v. 46, n. 2, p. 119, doi. 10.1007/s002800000132

By:

Huitema, Alwin D. R.;
Kerbusch, Thomas;
Tibben, Matthijs M.;
Rodenhuis, Sjoerd;
Beijnen, Jos H.

Publication type:

Article

N,N-diethyl-2-[4-(phenylmethyl)phenoxy] ethanamine (DPPE) a chemopotentiating and cytoprotective agent in clinical trials: interaction with histamine at cytochrome P450 3A4 and other isozymes that metabolize antineoplastic drugs.

Published in:

2000

By:

Brandes, Lorne J.;
Queen, Gary M.;
LaBella, Frank S.;
Brandes, L J;
Queen, G M;
LaBella, F S

Publication type:

journal article

Stimulation of Diethylnitrosamine Metabolism Reduces Its General Toxic and Hepatocarcinogenic Effects.

Published in:

Bulletin of Experimental Biology & Medicine, 2016, v. 162, n. 1, p. 98, doi. 10.1007/s10517-016-3555-3

By:

Il'nitskaya, S.;
Kaledin, V.;
Bogdanova, L.;
Morozkova, T.;
Kapustina, V.;
Perepechaeva, M.;
Grishanova, A.

Publication type:

Article

Identification of human uridine diphosphateglucuronosyltransferase isoforms responsible for the glucuronidation of 10,11-dihydro-10-hydroxy-carbazepine.

Published in:

Journal of Pharmacy & Pharmacology, 2021, v. 73, n. 3, p. 388, doi. 10.1093/jpp/rgaa059

By:

Kai Huang;
Linling Que;
Ying Ding;
Nannan Chu;
Zhenzhong Qian;
Wei Qin;
Yuanxing Chen;
Jisheng Zhang;
Qing He

Publication type:

Article

Evaluation of the time‐dependent antiproliferative activity and liver microsome stability of 3 phenyl 4‐(2‐oxo‐3‐alkylimidazolidin‐1‐yl)benzenesulfonates as promising CYP1A1‐dependent antimicrotubule prodrugs

Published in:

Journal of Pharmacy & Pharmacology, 2020, v. 72, n. 2, p. 249, doi. 10.1111/jphp.13198

By:

Zarifi Khosroshahi, Mitra;
Corin Chavez Alvarez, Atziri;
Gagné‐Boulet, Mathieu;
C.‐Gaudreault, René;
Gobeil, Stéphane;
Fortin, Sébastien

Publication type:

Article

The in-vitro effect of complementary and alternative medicines on cytochrome P450 2C9 activity.

Published in:

Journal of Pharmacy & Pharmacology, 2014, v. 66, n. 9, p. 1339, doi. 10.1111/jphp.12259

By:

Mooiman, Kim D.;
Goey, Andrew K.L.;
Huijbregts, Tomy J.;
Maas‐Bakker, Roel F.;
Beijnen, Jos H.;
Schellens, Jan H.M.;
Meijerman, Irma

Publication type:

Article

Glucuronidation of the broad-spectrum antiviral drug arbidol by UGT isoforms.

Published in:

Journal of Pharmacy & Pharmacology, 2013, v. 65, n. 4, p. 521, doi. 10.1111/jphp.12014

By:

Song, Jin‐Hui;
Fang, Zhong‐Ze;
Zhu, Liang‐Liang;
Cao, Yun‐Feng;
Hu, Cui‐Min;
Ge, Guang‐Bo;
Zhao, De‐Wei

Publication type:

Article

Astragaloside IV inhibited the activity of CYP1 A2 in liver microsomes and influenced theophylline pharmacokinetics in rats.

Published in:

Journal of Pharmacy & Pharmacology, 2013, v. 65, n. 1, p. 149, doi. 10.1111/j.2042-7158.2012.01579.x

By:

Zhang, Yan‐Hui;
Zhang, You‐Jin;
Guo, Yan‐Lei;
Li, Wen‐Juan;
Yu, Chao

Publication type:

Article

In-vitro metabolism of glycyrrhetinic acid by human and rat liver microsomes and its interactions with six CYP substrates.

Published in:

Journal of Pharmacy & Pharmacology, 2012, v. 64, n. 10, p. 1445, doi. 10.1111/j.2042-7158.2012.01516.x

By:

Zhao, Kai;
Ding, Ming;
Cao, Hui;
Cao, Zheng-xin

Publication type:

Article

Inhibition of human liver microsomal CYP by nateglinide.

Published in:

Journal of Pharmacy & Pharmacology, 2010, v. 62, n. 5, p. 592, doi. 10.1211/jpp.62.05.0005

By:

Takanohashi, Toshiyuki;
Kubo, Satoru;
Nakayama, Akira;
Mihara, Ryuichi;
Hayashi, Masahiro

Publication type:

Article

Effect of hepatic CYP inhibitors on the metabolism of sildenafil and formation of its metabolite, N-desmethylsildenafil, in rats in vitroand in vivo.

Published in:

Journal of Pharmacy & Pharmacology, 2009, v. 61, n. 12, p. 1637, doi. 10.1211/jpp.61.12.0008

By:

Soo H. Bae;
Soo K. Bae;
Myung G. Lee

Publication type:

Article

In-vitro and in-vivo metabolic studies of the candidate chemopreventative pentamethylchromanol using liquid chromatography/tandem mass spectrometry.

Published in:

Journal of Pharmacy & Pharmacology, 2009, v. 61, n. 10, p. 1309, doi. 10.1211/jpp.61.10.0006

By:

Gregory S. Gorman;
Lori Coward;
Corenna Kerstner-Wood;
Lea Freeman;
Charles D. Hebert;
Izet M. Kapetanovic

Publication type:

Article

Metabolism of two new benzodiazepine-type anti-leishmanial agents in rat hepatocytes and hepatic microsomes and their interaction with glutathione in macrophages.

Published in:

Journal of Pharmacy & Pharmacology, 2009, v. 61, n. 3, p. 399, doi. 10.1211/jpp/61.03.0017

By:

M. Dao Duong Thi;
M. Helen Grant;
Alexander Mullen;
Justice Tettey;
Simon MacKay;
Rachel Clark

Publication type:

Article

Prediction of human pharmacokinetics—gut-wall metabolism.

Published in:

Journal of Pharmacy & Pharmacology, 2007, v. 59, n. 10, p. 1335, doi. 10.1211/jpp.59.10.0002

By:

Urban Fagerholm

Publication type:

Article

Inhibition of in-vitro simvastatin metabolism in rat liver microsomes by bergamottin, a component of grapefruit juice.

Published in:

Journal of Pharmacy & Pharmacology, 2004, v. 56, n. 8, p. 1007

By:

N. Le Goff-Klein;
L. Klein;
M. Hérin;
J.-C. Koffel;
G. Ubeaud

Publication type:

Article

Ethanol inhibits in-vitro metabolism of nifedipine, triazolam and testosterone in human liver microsomes.

Published in:

Journal of Pharmacy & Pharmacology, 2004, v. 56, n. 8, p. 963

By:

Kiran C. Patki;
David J. Greenblatt;
Lisa L. von Moltke

Publication type:

Article

Inhibition of human cytochromes P450 by components of Ginkgo biloba.

Published in:

Journal of Pharmacy & Pharmacology, 2004, v. 56, n. 8, p. 1039

By:

Lisa L. von Moltke;
James L. Weemhoff;
Erdal Bedir;
Ikhlas A. Khan;
Jerold S. Harmatz;
Peter Goldman;
David J. Greenblatt

Publication type:

Article

Mineralisation of the herbicide linuron by Variovorax sp. strain RA8 isolated from Japanese river sediment using an ecosystem model (microcosm).

Published in:

Pest Management Science, 2010, v. 66, n. 8, p. 847, doi. 10.1002/ps.1951

By:

Satsuma, K.

Publication type:

Article

An analogue of piperonyl butoxide facilitates the characterisation of metabolic resistance.

Published in:

Pest Management Science, 2009, v. 65, n. 2, p. 150, doi. 10.1002/ps.1661

By:

Moores, Graham D.;
Despina Philippou;
Borzatta, Valerio;
Trincia, Paolo;
Jewess, Philip;
Gunningc, Robin;
Binghama, Georgina

Publication type:

Article

Oligonucleosome DNA Fragmentation of Caspase 3 Deficient MCF-7 Cells in Palmitate-Induced Apoptosis.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2004, v. 23, n. 6/7, p. 831, doi. 10.1081/NCN-200026024

By:

Semenov, D.V.;
Aronov, P.A.;
Kuligina, E.V.;
Potapenko, M.O.;
Richter, V.A.

Publication type:

Article

In vitro Metabolism of Risperidone on Isolated Microsomes of Rat Liver: Metabolite Identification and Profiling by RP-HPLC and LC-MS Techniques.

Published in:

Indian Journal of Pharmaceutical Education & Research, 2019, v. 53, p. S179, doi. 10.5530/ijper.53.2s.64

By:

Shirodkar, Prutha;
Chavan, Harshal;
Mogal, Rajendra;
Dhake, Avinash

Publication type:

Article

COMPARATIVE METABOLISM OF PHENANTHRO[3,4-B]THIOPHENE, PHENANTHRO[4,3-B]THIOPHENE AND THEIR CARBON ANALOG BENZO[C]PHENANTHRENE BY RAT LIVER MICROSOMES.

Published in:

Polycyclic Aromatic Compounds, 2004, v. 24, n. 4/5, p. 527, doi. 10.1080/10406630490471582

By:

Kumar, Subodh;
Kumar, Atul;
Sikka, HarishC.

Publication type:

Article

Glucuronidation of the Green Tea Catechins, (-)-epigallocatechin-3-gallate and (-)-epicatechin-3-gallate, by Rat Hepatic and Intestinal Microsomes.

Published in:

Free Radical Research, 2004, v. 38, n. 9, p. 1025, doi. 10.1080/10715760410001728424

By:

Crespy, Vanessa;
Nancoz, Nathalie;
Oliveria, Manuel;
Hau, Jörg;
Courtet-Compondu, Marie-Claude;
Williamson, Gary

Publication type:

Article

In Vitro and In Vivo Studies on Oxygen Free Radical and DNA Adduct Formation in Rat Lung and Liver during Benzo[a]pyrene Metabolism.

Published in:

Free Radical Research, 2004, v. 38, n. 9, p. 995, doi. 10.1080/10715760400000976

By:

Briedé, Jacob J.;
Godschalk, Roger W. L.;
Emans, Marijn T. G.;
De Kok, Theo M. C. M.;
Van Agen, Ebienus;
Van Maanen, Jan M. S.;
Van Schooten, Frederik-Jan;
Kleinjans, Jos C. S.

Publication type:

Article

Differential Role of CYP2E1 Binders and Isoniazid on CYP2E1 Protein Modification in NADPH-dependent Microsomal Oxidative Reactions: Free Radical Scavenging Ability of Isoniazid.

Published in:

Free Radical Research, 2002, v. 36, n. 8, p. 893

By:

Lenninger-Muller, Brigitte;
Young Chul Kim;
Dal Woong Choi, Brigitte;
Leroy, Pierre;
Siest, Gerard;
Wellman, Maria

Publication type:

Article

Sel1p/Ubx2p Participates in a Distinct Cdc48p-Dependent Endoplasmic Reticulum-Associated Degradation Pathway.

Published in:

Traffic, 2006, v. 7, n. 9, p. 1213, doi. 10.1111/j.1600-0854.2006.00460.x

By:

Wilson, Joshua D.;
Yiting Liu;
Bentivoglio, Christine M.;
Barlowe, Charles

Publication type:

Article

Acclimation temperature affects activities of 5'-nucleotidase and acid phosphatase and lipid and...

Published in:

Journal of Food Science (Wiley-Blackwell), 1994, v. 59, n. 5, p. 1009, doi. 10.1111/j.1365-2621.1994.tb08178.x

By:

Yang, S.A.;
Endo, K.

Publication type:

Article

Lipid Peroxidation Protection Factors in Rainbow Trout (Salmo gairdnerii) Muscle Cytosol.

Published in:

Journal of Food Science (Wiley-Blackwell), 1989, v. 54, n. 4, p. 809, doi. 10.1111/j.1365-2621.1989.tb07888.x

By:

HAN, T.J.;
LISTON, J.

Publication type:

Article

Enzymic lipid peroxidation in microsomes of chicken skeletal muscle

Published in:

Journal of Food Science (Wiley-Blackwell), 1976, v. 41, n. 6, p. 1488

By:

Hultin, H. O.;
Lin, T. -S.

Publication type:

Article

Metabolism and toxicity of usnic acid and barbatic acid based on microsomes, S9 fraction, and 3T3 fibroblasts in vitro combined with a UPLC-Q-TOF-MS method.

Published in:

Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1207928

By:

Hanxue Wang;
Min Xuan;
Juanjuan Diao;
Nan Xu;
Manlin Li;
Cheng Huang;
Changhong Wang

Publication type:

Article

Autoantibodies to thyroid peroxidase in patients with chronic thyroiditis: effect of antibody binding on enzyme activities.

Published in:

Clinical & Experimental Immunology, 1986, v. 65, n. 3, p. 534

By:

Kohno, Y.;
Hiyama, Y.;
Shimojo, N.;
Niimi, H.;
Nakajima, H.;
Hosoya, T.

Publication type:

Article