Works matching DE "DNA polymerases"

Results: 5000

Evaluating the Antiviral Potential of Polyherbal Formulation (Kabasura Kudineer) Against Monkeypox Virus: Targeting E5, Poxin, and DNA Polymerase Through Multifaceted Drug Discovery Approaches.

Published in:

Life (2075-1729), 2025, v. 15, n. 5, p. 771, doi. 10.3390/life15050771

By:

Priya, Sivan Padma;
Amalraj, Singamoorthy;
Padmanabhan, Vivek;
Rahman, Mohammed Mustahsen;
Chaitanya, Nallan CSK;
Hashim, Nada Tawfig;
Prabhu, Srinivasan;
Ayyanar, Muniappan;
Gurav, Shailendra;
Ceasar, Stanislaus Antony;
Thiruvengadam, Rekha

Publication type:

Article

PARP Inhibitors Show Promise for Hard-to-Treat Breast Cancers.

Published in:: Oncology (08909091), 2009, v. 23, n. 7, p. 638
Publication type:: Article

A unique binding mode enables MCM2 to chaperone histones H3-H4 at replication forks.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 8, p. 618, doi. 10.1038/nsmb.3055

By:

Huang, Hongda;
Strømme, Caroline B;
Saredi, Giulia;
Hödl, Martina;
Strandsby, Anne;
González-Aguilera, Cristina;
Chen, Shoudeng;
Groth, Anja;
Patel, Dinshaw J

Publication type:

Article

Structures of human DNA polymerases ν and θ expose their end game.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 4, p. 273, doi. 10.1038/nsmb.3006

By:

Beard, William A;
Wilson, Samuel H

Publication type:

Article

Human DNA polymerase θ grasps the primer terminus to mediate DNA repair.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 4, p. 304, doi. 10.1038/nsmb.2993

By:

Zahn, Karl E;
Averill, April M;
Aller, Pierre;
Wood, Richard D;
Doublié, Sylvie

Publication type:

Article

A global profile of replicative polymerase usage.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 3, p. 192, doi. 10.1038/nsmb.2962

By:

Daigaku, Yasukazu;
Keszthelyi, Andrea;
Müller, Carolin A;
Miyabe, Izumi;
Brooks, Tony;
Retkute, Renata;
Hubank, Mike;
Nieduszynski, Conrad A;
Carr, Antony M

Publication type:

Article

Mechanism of microhomology-mediated end-joining promoted by human DNA polymerase θ.

Published in:

Nature Structural & Molecular Biology, 2015, v. 22, n. 3, p. 230, doi. 10.1038/nsmb.2961

By:

Kent, Tatiana;
Chandramouly, Gurushankar;
McDevitt, Shane Michael;
Ozdemir, Ahmet Y;
Pomerantz, Richard T

Publication type:

Article

Reconstitution of active human core Mediator complex reveals a critical role of the MED14 subunit.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 12, p. 1028, doi. 10.1038/nsmb.2914

By:

Cevher, Murat A;
Shi, Yi;
Li, Dan;
Chait, Brian T;
Malik, Sohail;
Roeder, Robert G

Publication type:

Article

Mechanism of asymmetric polymerase assembly at the eukaryotic replication fork.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 8, p. 664, doi. 10.1038/nsmb.2851

By:

Georgescu, Roxana E;
Langston, Lance;
Yao, Nina Y;
Yurieva, Olga;
Zhang, Dan;
Finkelstein, Jeff;
Agarwal, Tani;
O'Donnell, Mike E

Publication type:

Article

Delivering nonidentical twins.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 8, p. 649, doi. 10.1038/nsmb.2852

By:

Kunkel, Thomas A;
Burgers, Peter M

Publication type:

Article

Ty3 reverse transcriptase complexed with an RNA-DNA hybrid shows structural and functional asymmetry.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 4, p. 389, doi. 10.1038/nsmb.2785

By:

Nowak, Elżbieta;
Miller, Jennifer T;
Bona, Marion K;
Studnicka, Justyna;
Szczepanowski, Roman H;
Jurkowski, Jakub;
Le Grice, Stuart F J;
Nowotny, Marcin

Publication type:

Article

Sustained active site rigidity during synthesis by human DNA polymerase μ.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 3, p. 253, doi. 10.1038/nsmb.2766

By:

Moon, Andrea F;
Pryor, John M;
Ramsden, Dale A;
Kunkel, Thomas A;
Bebenek, Katarzyna;
Pedersen, Lars C

Publication type:

Article

Look Ma, no PCNA: how DNA polymerase ε synthesizes long stretches of DNA without a processivity factor.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 1, p. 12, doi. 10.1038/nsmb.2749

By:

Zahn, Karl E;
Doublié, Sylvie

Publication type:

Article

PrimPol breaks replication barriers.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 12, p. 1348, doi. 10.1038/nsmb.2727

By:

Helleday, Thomas

Publication type:

Article

DNA pol in action.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 8, p. 922, doi. 10.1038/nsmb.2651

By:

Moorefield, Beth

Publication type:

Article

Preferential D-loop extension by a translesion DNA polymerase underlies error-prone recombination.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 6, p. 748, doi. 10.1038/nsmb.2573

By:

Pomerantz, Richard T;
Kurth, Isabel;
Goodman, Myron F;
O'Donnell, Mike E

Publication type:

Article

Structure of active dimeric human telomerase.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 4, p. 454, doi. 10.1038/nsmb.2530

By:

Sauerwald, Anselm;
Sandin, Sara;
Cristofari, Gaël;
Scheres, Sjors H W;
Lingner, Joachim;
Rhodes, Daniela

Publication type:

Article

Human RECQ1 promotes restart of replication forks reversed by DNA topoisomerase I inhibition.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 3, p. 347, doi. 10.1038/nsmb.2501

By:

Berti, Matteo;
Chaudhuri, Arnab Ray;
Thangavel, Saravanabhavan;
Gomathinayagam, Shivasankari;
Kenig, Sasa;
Vujanovic, Marko;
Odreman, Federico;
Glatter, Timo;
Graziano, Simona;
Mendoza-Maldonado, Ramiro;
Marino, Francesca;
Lucic, Bojana;
Biasin, Valentina;
Gstaiger, Matthias;
Aebersold, Ruedi;
Sidorova, Julia M;
Monnat, Raymond J;
Lopes, Massimo;
Vindigni, Alessandro

Publication type:

Article

DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 11, p. 1084, doi. 10.1038/nsmb.2395

By:

Mosbech, Anna;
Gibbs-Seymour, Ian;
Kagias, Konstantinos;
Thorslund, Tina;
Beli, Petra;
Povlsen, Lou;
Nielsen, Sofie Vincents;
Smedegaard, Stine;
Sedgwick, Garry;
Lukas, Claudia;
Hartmann-Petersen, Rasmus;
Lukas, Jiri;
Choudhary, Chunaram;
Pocock, Roger;
Bekker-Jensen, Simon;
Mailand, Niels

Publication type:

Article

Single-molecule studies reveal the function of a third polymerase in the replisome.

Published in:

Nature Structural & Molecular Biology, 2012, v. 19, n. 1, p. 113, doi. 10.1038/nsmb.2179

By:

Georgescu, Roxana E;
Kurth, Isabel;
O'Donnell, Mike E

Publication type:

Article

Tel1ATM and Rad3ATR kinases promote Ccq1-Est1 interaction to maintain telomeres in fission yeast.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 12, p. 1408, doi. 10.1038/nsmb.2187

By:

Moser, Bettina A;
Chang, Ya-Ting;
Kosti, Jorgena;
Nakamura, Toru M

Publication type:

Article

The RNA accordion model for template positioning by telomerase RNA during telomeric DNA synthesis.

Published in:

Nature Structural & Molecular Biology, 2011, v. 18, n. 12, p. 1371, doi. 10.1038/nsmb.2174

By:

Berman, Andrea J;
Akiyama, Benjamin M;
Stone, Michael D;
Cech, Thomas R

Publication type:

Article

Mutagenic conformation of 8-oxo-7,8-dihydro-2′-dGTP in the confines of a DNA polymerase active site.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 7, p. 889, doi. 10.1038/nsmb.1852

By:

Batra, Vinod K.;
Beard, William A.;
Hou, Esther W.;
Pedersen, Lars C.;
Prasad, Rajendra;
Wilson, Samuel H.

Publication type:

Article

Structural basis for telomerase catalytic subunit TERT binding to RNA template and telomeric DNA.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 4, p. 513, doi. 10.1038/nsmb.1777

By:

Mitchell, Meghan;
Gillis, Andrew;
Futahashi, Mizuko;
Fujiwara, Haruhiko;
Skordalakes, Emmanuel

Publication type:

Article

Structure of monoubiquitinated PCNA and implications for translesion synthesis and DNA polymerase exchange.

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 4, p. 479, doi. 10.1038/nsmb.1776

By:

Freudenthal, Bret D.;
Gakhar, Lokesh;
Ramaswamy, S.;
Washington, M. Todd

Publication type:

Article

Solution structures of the two PBZ domains from human APLF and their interaction with poly(ADP-ribose).

Published in:

Nature Structural & Molecular Biology, 2010, v. 17, n. 2, p. 241, doi. 10.1038/nsmb.1747

By:

Eustermann, Sebastian;
Brockmann, Christoph;
Mehrotra, Pawan Vinod;
Ji-Chun Yang;
Loakes, David;
West, Stephen C.;
Ahel, Ivan;
Neuhaus, David

Publication type:

Article

Template strand scrunching during DNA gap repair synthesis by human polymerase λ.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 9, p. 967, doi. 10.1038/nsmb.1654

By:

Garcia-Diaz, Miguel;
Bebenek, Katarzyna;
Larrea, Andres A.;
Havener, Jody M.;
Perera, Lalith;
Krahn, Joseph M.;
Pedersen, Lars C.;
Ramsden, Dale A.;
Kunkel, Thomas A.

Publication type:

Article

Structural basis of high-fidelity DNA synthesis by yeast DNA polymerase δ.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 9, p. 979, doi. 10.1038/nsmb.1663

By:

Swan, Michael K.;
Johnson, Robert E.;
Prakash, Louise;
Prakash, Satya;
Aggarwal, Aneel K.

Publication type:

Article

Dynamics and function of compact nucleosome arrays.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 9, p. 938, doi. 10.1038/nsmb.1650

By:

Poirier, Michael G.;
Oh, Eugene;
Tims, Hannah S.;
Widom, Jonathan

Publication type:

Article

Decapping is preceded by 3′ uridylation in a novel pathway of bulk mRNA turnover.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 6, p. 616, doi. 10.1038/nsmb.1601

By:

Rissland, Olivia S.;
Norbury, Chris J.

Publication type:

Article

Nucleic acid polymerases use a general acid for nucleotidyl transfer.

Published in:

Nature Structural & Molecular Biology, 2009, v. 16, n. 2, p. 212, doi. 10.1038/nsmb.1540

By:

Castro, Christian;
Smidansky, Eric D;
Arnold, Jamie J;
Maksimchuk, Kenneth R;
Moustafa, Ibrahim;
Uchida, Akira;
Götte, Matthias;
Konigsberg, William;
Cameron, Craig E

Publication type:

Article

PARP: a transferase by any other name.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 12, p. 1243, doi. 10.1038/nsmb1208-1243

By:

Till, Susanne;
Diamantara, Konstantina;
Ladurner, Andreas G.

Publication type:

Article

An equivalent metal ion in one- and two-metal-ion catalysis.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 11, p. 1228, doi. 10.1038/nsmb.1502

By:

Wei Yang

Publication type:

Article

The structural basis for cap binding by influenza virus polymerase subunit PB2.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 5, p. 500, doi. 10.1038/nsmb.1421

By:

Guilligay, Delphine;
Tarendeau, Franck;
Resa-Infante, Patricia;
Coloma, Rocío;
Crepin, Thibaut;
Sehr, Peter;
Lewis, Joe;
Ruigrok, Rob W. H.;
Ortin, Juan;
Hart, Darren J.;
Cusack, Stephen

Publication type:

Article

Single-molecule studies of fork dynamics in Escherichia coli DNA replication.

Published in:

Nature Structural & Molecular Biology, 2008, v. 15, n. 2, p. 170, doi. 10.1038/nsmb.1381

By:

Tanner, Nathan A.;
Hamdan, Samir M.;
Jergic, Slobodan;
Schaeffer, Patrick M.;
Dixon, Nicholas E.;
van Oijen, Antoine M.

Publication type:

Article

Addendum: Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 10, p. 984, doi. 10.1038/nsmb1007-984a

By:

Jacobs, Steven A.;
Podell, Elaine R.;
Cech, Thomas R.

Publication type:

Article

Rad54 dissociates homologous recombination intermediates by branch migration.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 8, p. 746, doi. 10.1038/nsmb1268

By:

Bugreev, Dmitry V.;
Hanaoka, Fumio;
Mazin, Alexander V.

Publication type:

Article

Corrigendum: Structural insight into the substrate specificity of DNA Polymerase μ.

Published in:

2007

By:

Moon, Andrea F.;
Garcia-Diaz, Miguel;
Bebenek, Katarzyna;
Davis, Bryan J.;
Xuejun Zhong;
Ramsden, Dale A.;
Kunkel, Thomas A.;
Pedersen, Lars C.

Publication type:

Correction Notice

RAD51, BRCA2 and DNA repair: a partial resolution.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 6, p. 461, doi. 10.1038/nsmb0607-461

By:

Lord, Christopher J.;
Ashworth, Alan

Publication type:

Article

Structure and nuclear import function of the C-terminal domain of influenza virus polymerase PB2 subunit.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 3, p. 229, doi. 10.1038/nsmb1212

By:

Tarendeau, Franck;
Boudet, Julien;
Guilligay, Delphine;
Mas, Philippe J.;
Bougault, Catherine M.;
Boulo, Sébastien;
Baudin, Florence;
Ruigrok, Rob W. H.;
Daigle, Nathalie;
Ellenberg, Jan;
Cusack, Stephen;
Simorre, Jean-Pierre;
Hart, Darren J.

Publication type:

Article

Structural insight into the substrate specificity of DNA Polymerase μ.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 1, p. 45, doi. 10.1038/nsmb1180

By:

Moon, Andrea F.;
Garcia-Diaz, Miguel;
Bebenek, Katarzyna;
Davis, Bryan J.;
Zhong, Xuejun;
Ramsden, Dale A.;
Kunkel, Thomas A.;
Pedersen, Lars C.

Publication type:

Article

Research Highlights.

Published in:: Nature Structural & Molecular Biology, 2006, v. 13, n. 11, p. 956, doi. 10.1038/nsmb1106-956
Publication type:: Article

The Pol II initiation complex: finding a place to start.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 7, p. 564, doi. 10.1038/nsmb0706-564

By:

Hampsey, Michael

Publication type:

Article

Hoogsteen base pair formation promotes synthesis opposite the 1,N6-ethenodeoxyadenosine lesion by human DNA polymerase ι.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 7, p. 619, doi. 10.1038/nsmb1118

By:

Nair, Deepak T.;
Johnson, Robert E.;
Prakash, Louise;
Prakash, Satya;
Aggarwal, Aneel K.

Publication type:

Article

Crystal structure of the essential N-terminal domain of telomerase reverse transcriptase.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 3, p. 218, doi. 10.1038/nsmb1054

By:

Jacobs, Steven A.;
Podell, Elaine R.;
Cech, Thomas R.

Publication type:

Article

Structure of an RNA polymerase II–RNA inhibitor complex elucidates transcription regulation by noncoding RNAs.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 1, p. 44, doi. 10.1038/nsmb1032

By:

Kettenberger, Hubert;
Eisenführ, Alexander;
Brueckner, Florian;
Theis, Mirko;
Famulok, Michael;
Cramer, Patrick

Publication type:

Article

Structure of Saccharomyces cerevisiae DNA polymerase epsilon by cryo–electron microscopy.

Published in:

Nature Structural & Molecular Biology, 2006, v. 13, n. 1, p. 35, doi. 10.1038/nsmb1040

By:

Asturias, Francisco J.;
Cheung, Iris K.;
Sabouri, Nasim;
Chilkova, Olga;
Wepplo, Daniel;
Johansson, Erik

Publication type:

Article

The Cbf5–Nop10 complex is a molecular bracket that organizes box H/ACA RNPs.

Published in:

Nature Structural & Molecular Biology, 2005, v. 12, n. 12, p. 1101, doi. 10.1038/nsmb1036

By:

Hamma, Tomoko;
Reichow, Steve L.;
Varani, Gabriele;
Ferré-D'Amaré, Adrian R.

Publication type:

Article

HIV: Do the flip.

Published in:

Nature Reviews Microbiology, 2008, v. 6, n. 7, p. 500, doi. 10.1038/nrmicro1934

By:

Mullard, Asher

Publication type:

Article

Should we include connection domain mutations of HIV-1 reverse transcriptase in HIV resistance testing.

Published in:

2007

By:

Götte, Matthias;
Götte, Matthias

Publication type:

journal article