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Title

Structural Elucidation of Some Flavonoids Isolated from Litsea costalis and Their Biological Evaluation.

Authors

Hamidi, Hani; Hosseinzadeh, Masoumeh; Zareyee, Daryoush; Khalilzadeh, Mohammad A.

Abstract

Litsea costalis is a well-known medicinal plant in tropical and subtropical areas. Four significant flavonoids were extracted and characterized from the plant leaf extract. One component was discovered for the first time in flavonoid chemistry, flavan-4-ol, (3′, 4′-methylenedioxy-5,7-dimethoxy chroman-4-ol). Three flavonoids were discovered for the first time in this plant. The detected products are ( )-pinostrobin, ( )-onysilin, and ( )-pinocembrin. The fourth component was characterized for the first time in this plant and introduced in flavonoid chemistry. The extracted component antioxidant activity against DPPH indicated an IC50 value of around 30 µg/mL.

Subjects

FLAVONOIDS; PLANT extracts; TROPICAL plants; MEDICINAL plants; FOLIAGE plants

Publication

Polycyclic Aromatic Compounds, 2025, Vol 45, Issue 1, p98

ISSN

1040-6638

Publication type

Academic Journal

DOI

10.1080/10406638.2024.2393249

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