Results
Title

Two new xyloketals from the endophytic fungus Endomelanconiopsis endophytica derived from medicinal plant Ficus hirta.

Authors

Sun, Zhang-Hua; Liang, Fa-Liang; Chen, Yu-Chan; Liu, Hong-Xin; Li, Hao-Hua; Zhang, Wei-Min

Abstract

Chemical examination of the liquid culture of Endomelanconiopsis endophytica A326 isolated from the Chinese folk medicine Ficus hirta resulted in the isolation of two new xyloketals named xyloketals K and L (1–2) and three known analogs (3–5) including a new natural product (5). Their structures were determined on the basis of extensive spectroscopic analysis. All compounds were evaluated for their cytotoxic activities against the SF-268, MCF-7, NCI-H460, and HepG-2 tumor cell lines. Nonetheless, no significant activity was observed.

Publication

Journal of Asian Natural Products Research, 2016, Vol 18, Issue 11, p1036

ISSN

1028-6020

Publication type

Academic Journal

DOI

10.1080/10286020.2016.1188084