Results
Title

Two new triterpenoid saponins from Ilex cornuta.

Authors

Wang, Ming-Lei; Liu, Yan-Li; Xu, Qiong-Ming; Li, Yun-Qiu; Yang, Shi-Lin

Abstract

Two new triterpenoid saponins (1 and 2) were isolated from the stems of Ilex cornuta, along with two known triterpenoids (3 and 4). The structures of compounds 1 and 2 were determined as ursane-12,19-diene-28-oic acid 3β-O-β-d-glucuronopyranoside-6-O-methyl ester (1), 3α,23α-dihydroxy-olean-9(11),12-diene-28-oic acid 28-O-β-d-glucopyranosyl ester (2), on the basis of hydrolysis and spectral evidence, including 1D and 2D NMR and high resolution electrospray ionization mass spectrometry (HR-ESI-MS) analyses. Protective effects of compounds 1–4 were tested against H2O2-induced H9c2 cardiomyocyte injury, and the data showed that all these compounds had no cell-protective effect.

Publication

Journal of Asian Natural Products Research, 2015, Vol 17, Issue 9, p908

ISSN

1028-6020

Publication type

Academic Journal

DOI

10.1080/10286020.2015.1040773