Title: Adlumiceine methyl ester, a new alkaloid from Fumaria vaillantii.
Authors: Iranshahy, Milad; Javidi-Shirazi, Hamideh; Pham, Ngoc B.; Quinn, Ronald J.; Sadeghian, Hamid; Iranshahi, Mehrdad
Abstract: A new alkaloid, adlumiceine methyl ester (1), together with two known alkaloids, parfumine (2) and N-methylhydrastine methyl ester (3), was isolated from aerial parts of Fumaria vaillantii. The structures of compounds were determined by 1D/2D NMR and MS data. All three compounds were tested for cytotoxic activity against PC3 and MCF7 cell lines using Alamar blue assay. The tested compounds showed no significant cytotoxic activity (IC50>50 μM) against PC3 and MCF7 cell lines.
Subjects: ALKALOIDS; ANTINEOPLASTIC agents; BIOLOGICAL assay; CELL culture; CHROMATOGRAPHIC analysis; DOXORUBICIN; MOLECULAR structure; NUCLEAR magnetic resonance spectroscopy; RESEARCH funding; TOXICITY testing; TUMORS; PLANT anatomy; DESCRIPTIVE statistics
Publication: Journal of Asian Natural Products Research, 2014, Vol 16, Issue 12, p1148
ISSN: 1028-6020
Publication type: Academic Journal
DOI: 10.1080/10286020.2014.969717

Adlumiceine methyl ester, a new alkaloid from Fumaria vaillantii.

Iranshahy, Milad; Javidi-Shirazi, Hamideh; Pham, Ngoc B.; Quinn, Ronald J.; Sadeghian, Hamid; Iranshahi, Mehrdad