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Title: Biological properties and molecular targets of umbelliprenin – a mini-review.
Authors: Shakeri, Abolfazl; Iranshahy, Milad; Iranshahi, Mehrdad
Abstract: 7-Prenyloxycoumarins are a group of secondary metabolites found mainly in plants belonging to the families Rutaceae and Apiaceae. Auraptene, umbelliprenin (UM), and 7-isopentenyloxycoumarin are some examples of prenylated coumarins. UM occurs in various edible plant species including celery, coriander, angelica, lemon, and particularly, Ferula species. Although UM was isolated more than 50 years ago, its biological activities have been studied since the last two decades. Besides anticancer activities, biological activities including anti-inflammatory, antioxidant, and antileishmanial activities have been reported from this natural compound. The present mini-review deals with the biological activities and mechanism of actions reported for UM.
Subjects: ANTI-inflammatory agents; ANTIBIOTICS; ANTINEOPLASTIC agents; ANTIOXIDANTS; BENZOPYRANS; CHOLINESTERASE inhibitors; MOLECULAR structure; THERAPEUTICS
Publication: Journal of Asian Natural Products Research, 2014, Vol 16, Issue 8, p884
ISSN: 1028-6020
Publication type: Academic Journal
DOI: 10.1080/10286020.2014.917630

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Biological properties and molecular targets of umbelliprenin – a mini-review.