Works matching Ligands (Biochemistry)

Results: 5000

Reversible Ligand Binding Reactions: WHY DO BIOCHEMISTRY STUDENTS HAVE TROUBLE CONNECTING THE DOTS?

Published in:

Biochemistry & Molecular Biology Education, 2007, v. 35, n. 2, p. 105, doi. 10.1002/bmb.29

By:

Sears, Duane W.;
Thompson, Scott E.;
Saxon, S. Robin

Publication type:

Article

Impact of Conformational Substates and Energy Landscapes on Understanding Hemoglobin Kinetics and Function.

Published in:

Journal of Biological Physics, 2021, v. 47, n. 4, p. 337, doi. 10.1007/s10867-021-09588-3

By:

Eaton, William A.

Publication type:

Article

Voltage-Dependent Gating in a "Voltage Sensor-Less" Ion Channel.

Published in:

PLoS Biology, 2010, v. 8, n. 2, p. 1, doi. 10.1371/journal.pbio.1000315

By:

Kurata, Harley T.;
Rapedius, Markus;
Kleinman, Marc J.;
Baukrowitz, Thomas;
Nichols, Colin G.

Publication type:

Article

The Structural Basis of Gas-Responsive Transcription by the Human Nuclear Hormone Receptor REV-ERB.

Published in:

PLoS Biology, 2009, v. 7, n. 2, p. e1000043, doi. 10.1371/journal.pbio.1000043

By:

Pardee, Keith I.;
Xu, Xiaohui;
Reinking, Jeff;
Schuetz, Anja;
Dong, Aiping;
Liu, Suya;
Zhang, Rongguang;
Tiefenbach, Jens;
Lajoie, Gilles;
Plotnikov, Alexander N.;
Botchkarev, Alexey;
Krause, Henry M.;
Edwards, Aled

Publication type:

Article

From ligands to behavioral outcomes: understanding the role of mineralocorticoid receptors in brain function.

Published in:

Stress: The International Journal on the Biology of Stress, 2023, v. 26, n. 1, p. 1, doi. 10.1080/10253890.2023.2204366

By:

Yang, Huanqing;
Narayan, Sowmya;
Schmidt, Mathias V.

Publication type:

Article

Thermodynamics of binding of regulatory ligands to tissue transglutaminase.

Published in:

Amino Acids, 2010, v. 39, n. 1, p. 297, doi. 10.1007/s00726-009-0442-5

By:

Bergamini, Carlo M.;
Dondi, Alessia;
Lanzara, Vincenzo;
Squerzanti, Monica;
Cervellati, Carlo;
Montin, Katy;
Mischiati, Carlo;
Tasco, Gianluca;
Collighan, Russel;
Griffin, Martin;
Casadio, Rita

Publication type:

Article

Control of protein-ligand recognition using a stimuli-responsive polymer.

Published in:

Nature, 1995, v. 378, n. 6556, p. 472, doi. 10.1038/378472a0

By:

Stayton, Patrick S.;
Shimoboji, Tsuyoshi

Publication type:

Article

Analyzing Ligand Depletion in a Saturation Equilibrium Binding Experiment.

Published in:

Biochemistry & Molecular Biology Education, 2006, v. 34, n. 6, p. 428, doi. 10.1002/bmb.2006.494034062677

By:

Enrique Claro

Publication type:

Article

TRPML1 gating modulation by allosteric mutations and lipids.

Published in:

eLife, 2024, p. 1

By:

Ninghai Gan;
Yan Han;
Weizhong Zeng;
Youxing Jiang

Publication type:

Article

LGR4 and LGR5 form distinct homodimers that only LGR4 complexes with RNF43/ZNRF3 to provide high affinity binding of R-spondin ligands.

Published in:

Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-37856-w

By:

Toh, Yukimatsu;
Wu, Ling;
Park, Soohyun;
Wang, Allison;
Tu, Jianghua;
Yu, Wangsheng;
Zuo, Mingxin;
Carmon, Kendra S.;
Liu, Qingyun J.

Publication type:

Article

LIGHT - ABSORPTION SPECTROSCOPY OF MUTAGEN - DNA COMPLEX : BINDING MODEL SELECTION AND BINDING PARAMETERS CALCULATION.

Published in:

Journal of Applied Electromagnetism, 2011, v. 13, n. 3, p. 15

By:

Iermak, Ie. L.

Publication type:

Article

A Novel Lectin (Morniga M) from Mulberry (Morus nigra) Bark Recognizes Oligomannosyl Residues in N-Glycans.

Published in:

Journal of Biomedical Science, 2004, v. 11, n. 6, p. 874, doi. 10.1159/000081835

By:

Wu, Albert M.;
Wu, June H.;
Singh, Tanuja;
Kang-Chuang Chu;
Peumans, Willy J.;
Rougé, Pierre;
Van Damme, Els J. M.

Publication type:

Article

The tubulin database: Linking mutations, modifications, ligands and local interactions.

Published in:

PLoS ONE, 2023, v. 18, n. 12, p. 1, doi. 10.1371/journal.pone.0295279

By:

Abbaali, Izra;
Truong, Danny;
Day, Shania Deon;
Mushayeed, Faliha;
Ganesh, Bhargavi;
Haro-Ramirez, Nancy;
Isles, Juliet;
Nag, Hindol;
Pham, Catherine;
Shah, Priya;
Tomar, Ishaan;
Manel-Romero, Carolina;
Morrissette, Naomi S.

Publication type:

Article

Quantification of the Cannabinoid Type 1 Receptor Availability in the Mouse Brain.

Published in:

Frontiers in Neuroanatomy, 2020, v. 14, p. N.PAG, doi. 10.3389/fnana.2020.593793

By:

Miederer, Isabelle;
Wiegand, Viktoria;
Bausbacher, Nicole;
Leukel, Petra;
Maus, Stephan;
Hoffmann, Manuela A.;
Lutz, Beat;
Schreckenberger, Mathias

Publication type:

Article

Molecular mechanism of α2β1 integrin interaction with human echovirus 1.

Published in:

EMBO Journal, 2010, v. 29, n. 1, p. 196, doi. 10.1038/emboj.2009.326

By:

Jokinen, Johanna;
White, Daniel J.;
Salmela, Maria;
Huhtala, Mikko;
Käpylä, Jarmo;
Sipilä, Kalle;
Puranen, J. Santeri;
Nissinen, Liisa;
Kankaanpää, Pasi;
Marjomäki, Varpu;
Hyypiä, Timo;
Johnson, Mark S.;
Heino, Jyrki

Publication type:

Article

Structural and functional characterization of a novel type of ligand-independent RXR-USP receptor.

Published in:

EMBO Journal, 2007, v. 26, n. 16, p. 3770, doi. 10.1038/sj.emboj.7601810

By:

Iwema, Thomas;
Billas, Isabelle ML;
Beck, Yannick;
Bonneton, François;
Nierengarten, Hélène;
Chaumot, Arnaud;
Richards, Geoff;
Laudet, Vincent;
Moras, Dino

Publication type:

Article

A danger of low copy numbers for inferring incorrect cooperativity degree.

Published in:

Theoretical Biology & Medical Modelling, 2010, v. 7, p. 40, doi. 10.1186/1742-4682-7-40

By:

Konkoli, Zoran

Publication type:

Article

Synthesis, computational and pharmacological evaluation of novel N-{4-[2-(4-aryl-piperazin-1-yl)ethyl]phenyl}-arylamides.

Published in:

Journal of the Serbian Chemical Society, 2024, v. 89, n. 3, p. 291, doi. 10.2298/JSC230906076A

By:

ANDRIĆ, DEANA B.;
DUKIĆ-STEFANOVIĆ, SLADJANA;
KRUNIĆ, MIHAJLO J.;
JEVTIĆ, IVANA I.;
PENJIŠEVIĆ, JELENA Z.;
ŠUKALOVIĆ, VLADIMIR B.;
KOSTIĆ-RAJAČIĆ, SLAĐANA

Publication type:

Article

Database of ligand-induced domain movements in enzymes.

Published in:

BMC Structural Biology, 2009, v. 9, p. 1, doi. 10.1186/1472-6807-9-13

By:

Guoying Qi;
Hayward, Steven

Publication type:

Article

The ins and outs of vanillyl alcohol oxidase: Identification of ligand migration paths.

Published in:

PLoS Computational Biology, 2017, v. 13, n. 10, p. 1, doi. 10.1371/journal.pcbi.1005787

By:

Gygli, Gudrun;
Lucas, Maria Fátima;
Guallar, Victor;
van Berkel, Willem J. H.

Publication type:

Article

Structural studies of the phosphatidylinositol 3-kinase (PI3K) SH3 domain in complex with a peptide ligand: role of the anchor residue in ligand binding.

Published in:

Biological Chemistry, 2010, v. 391, n. 1, p. 33, doi. 10.1515/BC.2010.003

By:

Batra-Safferling, Renu;
Granzin, Joachim;
Mödder, Susanne;
Hoffmann, Silke;
Willbold, Dieter

Publication type:

Article

Identification of heme as the ligand for the orphan nuclear receptors REV-ERBα and REV-ERBβ.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 12, p. 1207, doi. 10.1038/nsmb1344

By:

Raghuram, Srilatha;
Stayrook, Keith R.;
Huang, Pengxiang;
Rogers, Pamela M.;
Nosie, Amanda K.;
McClure, Don B.;
Burris, Lorri L.;
Khorasanizadeh, Sepideh;
Burris, Thomas P.;
Rastinejad, Fraydoon

Publication type:

Article

Structure-based design of a pathway-specific nuclear import inhibitor.

Published in:

Nature Structural & Molecular Biology, 2007, v. 14, n. 5, p. 452, doi. 10.1038/nsmb1229

By:

Cansizoglu, Ahmet E.;
Lee, Brittany J.;
Zi Chao Zhang;
Fontoura, Beatriz M. A.;
Yuh Min Chook

Publication type:

Article

Multi-scale simulation of L-selectin–PSGL-1-dependent homotypic leukocyte binding and rupture.

Published in:

Biomechanics & Modeling in Mechanobiology, 2010, v. 9, n. 5, p. 613, doi. 10.1007/s10237-010-0201-2

By:

Gupta, V. K.;
Sraj, Ihab;
Konstantopoulos, Konstantinos;
Eggleton, Charles D.

Publication type:

Article

Systematic Modification of the Substitution Pattern of the 7-Hydroxy-5-oxopyrazolo[4,3- b ]pyridine-6-carboxamide Scaffold Enabled the Discovery of New Ligands with High Affinity and Selectivity for the Cannabinoid Type 2 Receptor.

Published in:

Molecules, 2023, v. 28, n. 13, p. 4958, doi. 10.3390/molecules28134958

By:

Mugnaini, Claudia;
Kostrzewa, Magdalena;
Casini, Marta;
Kumar, Poulami;
Catallo, Valeria;
Allarà, Marco;
Guastaferro, Laura;
Brizzi, Antonella;
Paolino, Marco;
Tafi, Andrea;
Kapatais, Christelos;
Giorgi, Gianluca;
Vacondio, Federica;
Mor, Marco;
Corelli, Federico;
Ligresti, Alessia

Publication type:

Article

Novel Xanomeline-Containing Bitopic Ligands of Muscarinic Acetylcholine Receptors: Design, Synthesis and FRET Investigation.

Published in:

Molecules, 2023, v. 28, n. 5, p. 2407, doi. 10.3390/molecules28052407

By:

Matera, Carlo;
Kauk, Michael;
Cirillo, Davide;
Maspero, Marco;
Papotto, Claudio;
Volpato, Daniela;
Holzgrabe, Ulrike;
De Amici, Marco;
Hoffmann, Carsten;
Dallanoce, Clelia

Publication type:

Article

Capturing Peptide–GPCR Interactions and Their Dynamics.

Published in:

Molecules, 2020, v. 25, n. 20, p. 4724, doi. 10.3390/molecules25204724

By:

Kaiser, Anette;
Coin, Irene;
Ruzza, Paolo

Publication type:

Article

Application of 4D-QSAR Studies to a Series of Raloxifene Analogs and Design of Potential Selective Estrogen Receptor Modulators.

Published in:

Molecules, 2012, v. 17, n. 6, p. 7415, doi. 10.3390/molecules17067415

By:

Sodero, Ana Carolina Rennó;
Romeiro, Nelilma Correia;
Da Cunha, Elaine Fontes Ferreira;
De Oliveira Magalhães, Uiaran;
De Alencastro, Ricardo Bicca;
Rodrigues, Carlos Rangel;
Cabral, Lúcio Mendes;
Castro, Helena Carla;
Albuquerque, Magaly Girão

Publication type:

Article

Dimerization of Corticotropin-Releasing Factor Receptor Type 1 Is Not Coupled to Ligand Binding.

Published in:

Journal of Receptors & Signal Transduction, 2005, v. 25, n. 4-6, p. 251, doi. 10.1080/10799890500468838

By:

KRAETKE, OLIVER;
WIESNER, BURKHARD;
EICHHORST, JENNY;
FURKERT, JENS;
BIENERT, MICHAEL;
BEYERMANN, MICHAEL

Publication type:

Article

The Androgen Receptor in Prostate Cancer: Effect of Structure, Ligands and Spliced Variants on Therapy.

Published in:

Biomedicines, 2020, v. 8, n. 10, p. 422, doi. 10.3390/biomedicines8100422

By:

Messner, Elisabeth A.;
Steele, Thomas M.;
Tsamouri, Maria Malvina;
Hejazi, Nazila;
Gao, Allen C.;
Mudryj, Maria;
Ghosh, Paramita M.

Publication type:

Article

Old friends in new guise: repositioning of known drugs with structural bioinformatics.

Published in:

Briefings in Bioinformatics, 2011, v. 12, n. 4, p. 312, doi. 10.1093/bib/bbr011

By:

Haupt, V. Joachim;
Schroeder, Michael

Publication type:

Article

FINDSITE: a combined evolution/structure-based approach to protein function prediction.

Published in:

Briefings in Bioinformatics, 2009, v. 10, n. 4, p. 378, doi. 10.1093/bib/bbp017

By:

Skolnick, Jeffrey;
Brylinski, Michal

Publication type:

Article

Improvement of binding pose prediction of the MR1 covalent ligands by inclusion of simple pharmacophore constraints and structural waters in the docking process.

Published in:

3 Biotech, 2023, v. 13, n. 8, p. 1, doi. 10.1007/s13205-023-03694-w

By:

Shamsara, Jamal;
Schüürmann, Gerrit

Publication type:

Article

In-situ liquid cell transmission electron microscopy investigation on oriented attachment of gold nanoparticles.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-02925-6

By:

Chao Zhu;
Suxia Liang;
Erhong Song;
Yuanjun Zhou;
Wen Wang;
Feng Shan;
Yantao Shi;
Ce Hao;
Kuibo Yin;
Tong Zhang;
Jianjun Liu;
Haimei Zheng;
Litao Sun

Publication type:

Article

Single molecule high-throughput footprinting of small and large DNA ligands.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00379-w

By:

Manosas, Maria;
Camunas-Soler, Joan;
Croquette, Vincent;
Ritort, Felix

Publication type:

Article

Predicting target-ligand interactions using protein ligand-binding site and ligand substructures.

Published in:

BMC Systems Biology, 2015, v. 9, p. 1, doi. 10.1186/1752-0509-9-S1-S2

By:

Caihua Wang;
Juan Liu;
Fei Luo;
Zixing Deng;
Qian-Nan Hu

Publication type:

Article

An ab initio approach to the understanding of cytochrome P450-ligand interactions.

Published in:

Xenobiotica, 1998, v. 28, n. 1, p. 15, doi. 10.1080/004982598239713

By:

Segall, M. D.;
Payne, M. C.;
Ellis, S. W.;
Tucker, G. T.;
Boyes, R. N.

Publication type:

Article

Enhancement of enzyme efficiency and stability by incorporation of unnatural amino acid residues in a targeted functional site.

Published in:

FASEB Journal, 2007, v. 21, n. 6, p. A1012

By:

Hegazy, Usama M.;
Mannervik, Bengt

Publication type:

Article

pMD-Membrane: A Method for Ligand Binding Site Identification in Membrane-Bound Proteins.

Published in:

PLoS Computational Biology, 2015, v. 11, n. 10, p. 1, doi. 10.1371/journal.pcbi.1004469

By:

Prakash, Priyanka;
Sayyed-Ahmad, Abdallah;
Gorfe, Alemayehu A.

Publication type:

Article

Rational Engineering of Enzyme Allosteric Regulation through Sequence Evolution Analysis.

Published in:

PLoS Computational Biology, 2012, v. 8, n. 7, p. 1, doi. 10.1371/journal.pcbi.1002612

By:

Jae-Seong Yang;
Sang Woo Seo;
Sungho Jang;
Gyoo Yeol Jung;
Sanguk Kim

Publication type:

Article

The carbon reactions of photosynthesis: role of lectins and glycoregulation.

Published in:

Photosynthetica, 2020, v. 58, n. 5, p. 1090, doi. 10.32615/ps.2020.064

By:

NONOMURA, A. M.;
SHEVELA, D.;
KOMATH, S. S.;
BIEL, K. Y.;
GOVINDJEE, G.

Publication type:

Article

Quantum simulations of SARS-CoV-2 main protease M<sup>pro</sup> enable high-quality scoring of diverse ligands.

Published in:

Journal of Computer-Aided Molecular Design, 2021, v. 35, n. 9, p. 963, doi. 10.1007/s10822-021-00412-7

By:

Wang, Yuhang;
Murlidaran, Sruthi;
Pearlman, David A.

Publication type:

Article

Structure-based identification of inhibitors disrupting the CD2–CD58 interactions.

Published in:

Journal of Computer-Aided Molecular Design, 2021, v. 35, n. 3, p. 337, doi. 10.1007/s10822-020-00369-z

By:

Tripathi, Neha;
Leherte, Laurence;
Vercauteren, Daniel P.;
Laurent, Adèle D.

Publication type:

Article

Theoretical models to predict the inhibitory effect of ligands of sphingosine kinase 1 using QTAIM calculations and hydrogen bond dynamic propensity analysis.

Published in:

Journal of Computer-Aided Molecular Design, 2018, v. 32, n. 7, p. 781, doi. 10.1007/s10822-018-0129-7

By:

Vettorazzi, Marcela;
Menéndez, Cintia;
Gutiérrez, Lucas;
Andujar, Sebastián;
Appignanesi, Gustavo;
Enriz, Ricardo D.

Publication type:

Article

Influence of gauche effect on uncharged oxime reactivators for the reactivation of tabun-inhibited AChE: quantum chemical and steered molecular dynamics studies.

Published in:

Journal of Computer-Aided Molecular Design, 2018, v. 32, n. 7, p. 793, doi. 10.1007/s10822-018-0130-1

By:

Ghosh, Shibaji;
Jana, Kalyanashis;
Ganguly, Bishwajit

Publication type:

Article

Exploring ensembles of bioactive or virtual analogs of X-ray ligands for shape similarity searching.

Published in:

Journal of Computer-Aided Molecular Design, 2018, v. 32, n. 7, p. 759, doi. 10.1007/s10822-018-0128-8

By:

Miyao, Tomoyuki;
Bajorath, Jürgen

Publication type:

Article

Quantitative surface field analysis: learning causal models to predict ligand binding affinity and pose.

Published in:

Journal of Computer-Aided Molecular Design, 2018, v. 32, n. 7, p. 731, doi. 10.1007/s10822-018-0126-x

By:

Cleves, Ann E.;
Jain, Ajay N.

Publication type:

Article

A pose prediction approach based on ligand 3D shape similarity.

Published in:

Journal of Computer-Aided Molecular Design, 2016, v. 30, n. 6, p. 457, doi. 10.1007/s10822-016-9923-2

By:

Kumar, Ashutosh;
Zhang, Kam

Publication type:

Article

The DINGO dataset: a comprehensive set of data for the SAMPL challenge.

Published in:

Journal of Computer-Aided Molecular Design, 2012, v. 26, n. 5, p. 497, doi. 10.1007/s10822-011-9521-2

By:

Newman, Janet;
Dolezal, Olan;
Fazio, Vincent;
Caradoc-Davies, Tom;
Peat, Thomas

Publication type:

Article

Alchemical prediction of hydration free energies for SAMPL.

Published in:

Journal of Computer-Aided Molecular Design, 2012, v. 26, n. 5, p. 551, doi. 10.1007/s10822-011-9528-8

By:

Mobley, David;
Liu, Shaui;
Cerutti, David;
Swope, William;
Rice, Julia

Publication type:

Article