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- Title
Ovarian steroids and cancer: news on the breast, questions on the reproductive tract.
- Authors
Hidalgo-Mora, Juan J.; Tarín, Juan J.; Cano, Antonio
- Abstract
Interesting challenges ahead include uncovering the potential role of RANK/RANKL in estrogen-dependent proliferation in the endometrium, and determining whether the progestogenic effect, which limits proliferation in the endometrium, is in any way related to the RANK/RANKL system. The association between steroid hormones and cancer has been a primary research focus for many years. Reproductive hormones are of particular interest given the fact that several highly prevalent cancers in women, such as breast or endometrial cancer [[1]], are paradigmatic examples of endocrine-related cancer.
- Subjects
RALOXIFENE; OVARIAN cancer; GENITALIA; OSTEOCLASTS; BREAST cancer; NF-kappa B; TUMOR necrosis factors
- Publication
Gynecological Endocrinology, 2021, Vol 37, Issue 5, p383
- ISSN
0951-3590
- Publication type
Academic Journal
- DOI
10.1080/09513590.2021.1904871