Title: Convergent synthesis of 4,5-branched inner-core oligosaccharides of lipopoly- and lipooligosaccharides.
Authors: Yi, Ruiqin; Narimoto, Hirofumi; Nozoe, Miku; Ichiyanagi, Tsuyoshi
Abstract: The convergent synthesis of branched inner-core oligosaccharides of lipopoly- and lipooligosaccharide with a 3-deoxy-d-manno-oct-2-ulosonic acid (Kdo) disaccharide acceptor was achieved. The l-glycero-d-manno-heptopyranose (Hep) units for the branched core oligosaccharide Galβ(1-4)Glcβ(1-4)Hep and Hepα(1-3)Hep were prepared from the corresponding Hep building blocks. To obtain 4,5-branched core oligosaccharide structures, the common acceptor Kdoα(2-4)Kdo was glycosylated with the Hep units.
Subjects: OLIGOSACCHARIDE synthesis; LIPOOLIGOSACCHARIDES; DISACCHARIDES
Publication: Bioscience, Biotechnology & Biochemistry, 2015, Vol 79, Issue 12, p1931
ISSN: 0916-8451
Publication type: Academic Journal
DOI: 10.1080/09168451.2015.1069698

Convergent synthesis of 4,5-branched inner-core oligosaccharides of lipopoly- and lipooligosaccharides.

Yi, Ruiqin; Narimoto, Hirofumi; Nozoe, Miku; Ichiyanagi, Tsuyoshi