Angiotensin receptor blockers and endpoint protection.

Kjeldsen, Sverre E.; Hedner, Thomas; Narkiewicz, Krzysztof

Comments that angiotensin receptor blockers (ARBs) are selective and specific antagonists of the type-1 angiotensin receptor. Indication for the treatment of hypertension; Combination of ARBs with any other class of antihypertensive drugs since these drugs block at a different site from the renin-angiotensin system compared with angiotensin-converting enzyme inhibitors; Reduction of peripheral vascular resistance while cardiac output is mainly unchanged; Normalization of the typical pathological vascular structure and function in hypertensive patients including the hemodynamic abnormalities.

ANGIOTENSINS; HYPERTENSION; THERAPEUTICS; BLOOD-vessel physiology; HEMODYNAMICS; PATIENTS

Blood Pressure, 2005, Vol 14, Issue 4, p195

0803-7051

Academic Journal

10.1080/08037050500224006