This theory-building case study examined the relational transactional analysis concept of empathic transactions (ETs) developed by Hargaden and Sills. The researchers analyzed the transactions between a 28-year-old woman and her therapist during their 26-session therapy. Client progress was assessed using the Assimilation of Problematic Experiences Sequence (APES) as well as standard symptom intensity inventories. Results were largely consistent with theoretical accounts offered by the concept of ETs in facilitating psychological change. All of the ETs were employed, but five of the ETs—inquiry, confrontation, specification, illustration, and explanation—were particularly useful in this case. Results also pointed to aspects of the theories that need refinement or modification. For example, the sequencing of ETs suggested by Hargaden and Sills was not uniformly confirmed.