Works matching DE "TABUN"

Results: 99

Evaluation of the Influence of Three Newly Developed Bispyridinium Anti‐nicotinic Compounds (MB408, MB442, MB444) on the Efficacy of Antidotal Treatment of Nerve Agent Poisoning in Mice.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2018, v. 122, n. 4, p. 429, doi. 10.1111/bcpt.12935

By:

Kassa, Jiri;
Timperley, Christopher M.;
Bird, Mike;
Williams, Rebecca L.;
Green, A. Christopher;
Tattersall, John E. H.

Publication type:

Article

Evaluation of the Potency of Two Novel Bispyridinium Oximes ( K456, K458) in Comparison with Oxime K203 and Trimedoxime to Counteract Tabun-Induced Neurotoxicity in Rats.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2013, v. 113, n. 3, p. 201, doi. 10.1111/bcpt.12083

By:

Kassa, Jiri;
Misik, Jan;
Karasova, Jana Z.

Publication type:

Article

Delayed Neurological Complications of Sulphur Mustard and Tabun Poisoning in 43 Iranian Veterans.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2012, v. 111, n. 6, p. 426, doi. 10.1111/j.1742-7843.2012.00922.x

By:

Darchini-Maragheh, Emadodin;
Nemati-Karimooy, Habibollah;
Hasanabadi, Hosein;
Balali-Mood, Mahdi

Publication type:

Article

Effects of Oxime K203 and Oxidative Stress in Plasma of Tabun Poisoned Rats.

Published in:

Croatica Chemica Acta, 2012, v. 85, n. 2, p. 193, doi. 10.5562/cca1811

By:

Berend, Suzana;
Vrdoljak, Ana Lucić;
Musilek, Kamil;
Kuča, Kamil;
Radić, Božica

Publication type:

Article

Reactivation of Tabun-inhibited Acetylcholinesterase Investigated by Two Oximes and Mutagenesis.

Published in:

Croatica Chemica Acta, 2012, v. 85, n. 2, p. 209, doi. 10.5562/cca1815

By:

Katalinić, Maja;
Kovarik, Zrinka

Publication type:

Article

Regulation of NCOA4-mediated iron recycling ameliorates paraquat-induced lung injury by inhibiting ferroptosis.

Published in:

Cell Communication & Signaling, 2024, v. 22, n. 1, p. 1, doi. 10.1186/s12964-024-01520-1

By:

Du, Jing;
Yu, Lingyan;
Yang, Xinyi;
Shao, Fangchun;
Xia, Jun;
Jin, Weidong;
Zhang, Yinhao;
Lei, Guojie;
Wang, Ying;
Li, Yanchun;
Zhang, Jun

Publication type:

Article

Reversal of Tabun Toxicity Enabled by a Triazole‐Annulated Oxime Library—Reactivators of Acetylcholinesterase.

Published in:

Chemistry - A European Journal, 2019, v. 25, n. 16, p. 4100, doi. 10.1002/chem.201805051

By:

Kovarik, Zrinka;
Kalisiak, Jarosław;
Hrvat, Nikolina Maček;
Katalinić, Maja;
Zorbaz, Tamara;
Žunec, Suzana;
Green, Carol;
Radić, Zoran;
Fokin, Valery V.;
Sharpless, K. Barry;
Taylor, Palmer

Publication type:

Article

Frontispiece: A Rapid and Sensitive Strip-Based Quick Test for Nerve Agents Tabun, Sarin, and Soman Using BODIPY-Modified Silica Materials.

Published in:

Chemistry - A European Journal, 2016, v. 22, n. 32, p. n/a, doi. 10.1002/chem.201683261

By:

ClimENt, Estela;
Biyikal, Mustafa;
Gawlitza, Kornelia;
Dropa, Tomáš;
Urban, Martin;
Costero, Ana M.;
Martínez ‐ Máñez, Ramón;
Rurack, Knut

Publication type:

Article

A tissue-bioengineering strategy for modeling rare human kidney diseases in vivo.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26596-y

By:

Hernandez, J. O. R.;
Wang, X.;
Vazquez-Segoviano, M.;
Lopez-Marfil, M.;
Sobral-Reyes, M. F.;
Moran-Horowich, A.;
Sundberg, M.;
Lopez-Cantu, D. O.;
Probst, C. K.;
Ruiz-Esparza, G. U.;
Giannikou, K.;
Abdi, R.;
Henske, E. P.;
Kwiatkowski, D. J.;
Sahin, M.;
Lemos, D. R.

Publication type:

Article

Does the syn- versus post-rift thickness ratio have an impact on the inversion-related structural style?

Published in:

Solid Earth Discussions, 2023, p. 1, doi. 10.5194/egusphere-2023-280

By:

Tamas, Alexandra;
Tamas, Dan M.;
Tari, Gabor;
Krezsek, Csaba;
Lapadat, Alexandru;
Schleder, Zsolt

Publication type:

Article

Chapter 17: Investigation of the Efficacy of New Reactivators of Cholinesterase in Soman and Tabun Inhibited Rat Brain Acetylcholinesterase.

Published in:

Journal of Medical Chemical, Biological & Radiological Defense, 2010, v. 8, p. 121

By:

Pencheva, Teodora;
Petrova, Iskra;
Samnaliev, Ivan;
Dishovsky, Christophor

Publication type:

Article

Chapter 16: Synthesis of New Reactivators of Cholinesterase.

Published in:

Journal of Medical Chemical, Biological & Radiological Defense, 2010, v. 8, p. 115

By:

Petrova, Iskra;
Samnaliev, Ivan;
Dishovsky, Christophor

Publication type:

Article

Chapter 13: Biological Markers of Intoxication with Nerve Agents - Biochemical investigations in rats poisoned with tabun.

Published in:

Journal of Medical Chemical, Biological & Radiological Defense, 2010, v. 8, p. 94

By:

Dishovsky, Christophor;
Samnaliev, Ivan;
Ivanov, Trifon;
Petrova, Iskra

Publication type:

Article

In Silico Studies in Probing the Role of Kinetic and Structural Effects of Different Drugs for the Reactivation of Tabun-Inhibited AChE.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0079591

By:

Lo, Rabindranath;
Chandar, Nellore Bhanu;
Kesharwani, Manoj K.;
Jain, Aastha;
Ganguly, Bishwajit

Publication type:

Article

Energetics of Ortho-7 (Oxime Drug) Translocation through the Active-Site Gorge of Tabun Conjugated Acetylcholinesterase.

Published in:

PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0040188

By:

Sinha, Vivek;
Ganguly, Bishwajit;
Bandyopadhyay, Tusar

Publication type:

Article

Click-chemistry-derived oxime library reveals efficient reactivators of nerve agent-inhibited butyrylcholinesterase suitable for pseudo-catalytic bioscavenging.

Published in:

Archives of Toxicology, 2025, v. 99, n. 5, p. 2107, doi. 10.1007/s00204-025-03985-6

By:

Čadež, Tena;
Maček Hrvat, Nikolina;
Šinko, Goran;
Kalisiak, Jarosław;
Radić, Zoran;
Fokin, Valery V.;
Sharpless, Karl Barry;
Taylor, Palmer;
Kovarik, Zrinka

Publication type:

Article

"Catch-up" therapy: combining antidotal treatment with dermal application of AHA following percutaneous VX poisoning in the domestic swine.

Published in:

Archives of Toxicology, 2023, v. 97, n. 10, p. 2771, doi. 10.1007/s00204-023-03574-5

By:

Bloch-Shilderman, Eugenia;
Nili, Uri;
Nahum, Victoria;
Smolkin, Boris;
Ashkenazi, Nissan

Publication type:

Article

Oxime K203: a drug candidate for the treatment of tabun intoxication.

Published in:

Archives of Toxicology, 2019, v. 93, n. 3, p. 673, doi. 10.1007/s00204-018-2377-7

By:

Kucera, Tomas;
Gorecki, Lukas;
Soukup, Ondrej;
Jun, Daniel;
Korabecny, Jan;
Malinak, David;
Kuca, Kamil;
Musilek, Kamil

Publication type:

Article

The influence of combinations of oximes on the reactivating and therapeutic efficacy of antidotal treatment of tabun poisoning in rats and mice.

Published in:

Journal of Applied Toxicology, 2010, v. 30, n. 2, p. 120, doi. 10.1002/jat.1477

By:

Kass, Jiri;
Karasov, Jana Zdarova;
Pavlikov, Ruzena;
Misik, Jan;
Caisberger, Filip;
Bajgar, Jiri

Publication type:

Article

Reactivation of organophosphate-inhibited human AChE by combinations of obidoxime and HI 6 in vitro.

Published in:

Journal of Applied Toxicology, 2007, v. 27, n. 6, p. 582, doi. 10.1002/jat.1241

By:

Worek, F.;
Aurbek, N.;
Thiermann, H.

Publication type:

Article

A comparison of the potency of newly developed oximes (K027, K048) and commonly used oximes (obidoxime, HI-6) to counteract tabun-induced neurotoxicity in rats.

Published in:

Journal of Applied Toxicology, 2006, v. 26, n. 4, p. 309, doi. 10.1002/jat.1137

By:

Kassa, Jiří;
Kunesova, Gabriela

Publication type:

Article

Effective bisquaternary reactivators of tabun‐inhibited AChE.

Published in:

Journal of Applied Toxicology, 2005, v. 25, n. 6, p. 491, doi. 10.1002/jat.1084

By:

Kamil Kuca;
Jiri Cabal;
Kamil Musilek;
Daniel Jun;
Jiri Bajgar

Publication type:

Article

Toxicity of the nerve agent tabun to Daphnia magna , a new experimental species in military toxicology.

Published in:

Chemistry & Ecology, 2006, v. 22, n. 2, p. 175, doi. 10.1080/02757540600579383

By:

Vesela, Sarka;
Kuca, Kamil;
Jun, Daniel

Publication type:

Article

The Large and Diverse Family of Mediterranean Flat Breads: A Database.

Published in:

Foods, 2022, v. 11, n. 15, p. 2326, doi. 10.3390/foods11152326

By:

Pasqualone, Antonella;
Vurro, Francesca;
Summo, Carmine;
Abd-El-Khalek, Mokhtar H.;
Al-Dmoor, Haneen H.;
Grgic, Tomislava;
Ruiz, Maria;
Magro, Christopher;
Deligeorgakis, Christodoulos;
Helou, Cynthia;
Le-Bail, Patricia

Publication type:

Article

Separation and Preconcentration Methods for the Determination of Highly Toxic Organic Compounds (Poisons).

Published in:

Journal of Analytical Chemistry, 2021, v. 76, n. 9, p. 1029, doi. 10.1134/S1061934821090070

By:

Leninskii, M. A.;
Shachneva, M. D.;
Savel'eva, E. I.;
Koryagina, N. L.

Publication type:

Article

How Dough Rises in Gaza: Palestine's Foremothers and Recipes against Genocide.

Published in:

Jerusalem Quarterly, 2024, n. 99, p. 56, doi. 10.70190/jq.i99.p56

By:

Sharif, Lila

Publication type:

Article

A comparison of the reactivating and therapeutic efficacy of newly developed oximes (K347, K628) with commonly used oximes (obidoxime, HI-6) against tabun in rats and mice.

Published in:

Drug & Chemical Toxicology, 2010, v. 33, n. 3, p. 227, doi. 10.3109/01480540903483409

By:

Kassa, Jiri;
Karasova, Jana Zdarova;
Kuca, Kamil;
Musilek, Kamil

Publication type:

Article

A Comparison of neuroprotective efficacy of newly developed oximes (K203, K206) and commonly used oximes (obidoxime, HI-6) in tabun-poisoned rats.

Published in:

Drug & Chemical Toxicology, 2009, v. 32, n. 2, p. 128, doi. 10.1080/01480540802593873

By:

Kassa, Jiri;
Karasova, Jana;
Vasina, Libor;
Bajgar, Jiri;
Kuca, Kamil;
Musilek, Kamil

Publication type:

Article

A Comparison of the Therapeutic and Reactivating Efficacy of Newly Developed Oximes (K117, K127) and Currently Available Oximes (Obidoxime, Trimedoxime, HI-6) in Tabun-Poisoned Rats and Mice.

Published in:

Drug & Chemical Toxicology, 2008, v. 31, n. 3, p. 371, doi. 10.1080/01480540802171258

By:

Kassa, Jiri;
Karasova, Jana;
Musilek, Kamil;
Kuca, Kamil;
Jung, Young-Sik

Publication type:

Article

A Comparison of the Potency of Newly Developed Oximes (K074, K075) and Currently Available Oximes (Obidoxime, Trimedoxime, Hi-6) to Counteract Acute Toxic Effects of Tabun and Cyclosarin in Mice.

Published in:

Drug & Chemical Toxicology, 2008, v. 31, n. 1, p. 127, doi. 10.1080/01480540701688816

By:

Kassa, Jiří;
Humlicek, Vojtech

Publication type:

Article

Reactivation of Immobilized Acetylcholinesterase-Tabun Complex by Methoxime and Its Homologues.

Published in:

Drug & Chemical Toxicology, 2007, v. 30, n. 2, p. 97, doi. 10.1080/01480540601186614

By:

Hoskovcová, Monika;
Halámek, Emil;
Kobliha, Zbyněk;
Tušarová, Ivana

Publication type:

Article

In Vitro Evaluation of Acetylcholinesterase Reactivators as Potential Antidotes Against Tabun Nerve Agent Poisonings.

Published in:

Drug & Chemical Toxicology, 2006, v. 29, n. 4, p. 443, doi. 10.1080/01480540600718565

By:

Kuca, Kamil;
Cabal, Jiri;
Jun, Daniel;
Hrabinova, Martina

Publication type:

Article

In vitro Reactivation Potency of Acetylcholinesterase Reactivators -- K074 and K075 -- to Reactivate Tabun-inhibited Human Brain Cholinesterases.

Published in:

Neurotoxicity Research, 2007, v. 11, n. 2, p. 101, doi. 10.1007/BF03033389

By:

Kuca, Kamil;
Cabal, Jiri;
Jun, Daniel;
Musilek, Kamil

Publication type:

Article

Changes of rat plasma total low molecular weight antioxidant level after tabun exposure and consequent treatment by acetylcholinesterase reactivators.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2011, v. 26, n. 1, p. 93, doi. 10.3109/14756361003733613

By:

Pohanka, Miroslav;
Karasova, Jana Zdarova;
Musilek, Kamil;
Kuca, Kamil;
Jung, Young-Sik;
Kassa, Jiri

Publication type:

Article

A comparison of tabun-inhibited rat brain acetylcholinesterase reactivation by three oximes (HI-6, obidoxime, and K048) in vivo detected by biochemical and histochemical techniques.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2010, v. 25, n. 6, p. 790, doi. 10.3109/14756360903433373

By:

Bajgar, Jiri;
Hajek, Petr;
Zdarova, Jana Karasova;
Kassa, Jiri;
Paseka, Antonin;
Slizova, Dasa;
Krs, Otakar;
Kuca, Kamil;
Jun, Daniel;
Fusek, Josef;
Capek, Lukas

Publication type:

Article

In vivo experimental approach to treatment against tabun poisoning.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2010, v. 25, n. 4, p. 531, doi. 10.3109/14756360903357593

By:

Berend, Suzana;
Katalinić, Maja;
Lucić Vrdoljak, Ana;
Kovarik, Zrinka;
Kuča, Kamil;
Radić, Božica

Publication type:

Article

A comparison of reactivating and therapeutic efficacy of the oxime K203 and its fluorinated analog (KR-22836) with currently available oximes (obidoxime, trimedoxime, HI-6) against tabun in rats and mice.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2010, v. 25, n. 4, p. 480, doi. 10.3109/14756360903257918

By:

Kassa, Jiri;
Karasova, Jana Zdarova;
Caisberger, Filip;
Musilek, Kamil;
Kuca, Kamil;
Jung, Young-Sik

Publication type:

Article

Oxime K027: novel low-toxic candidate for the universal reactivator of nerve agent- and pesticide-inhibited acetylcholinesterase.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2010, v. 25, n. 4, p. 509, doi. 10.3109/14756360903357569

By:

Kuca, Kamil;
Musilek, Kamil;
Jun, Daniel;
Pohanka, Miroslav;
Ghosh, Kallol Kumar;
Hrabinova, Martina

Publication type:

Article

A comparison of the reactivating and therapeutic efficacy of newly developed bispyridinium oximes (K250, K251) with commonly used oximes against tabun in rats and mice.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2009, v. 24, n. 4, p. 1040, doi. 10.1080/14756360802608419

By:

Kassa, Jiri;
Karasova, Jana;
Bajgar, Jiri;
Kuca, Kamil;
Musilek, Kamil;
Kopelikova, Irena

Publication type:

Article

Synthesis of a novel series of non-symmetrical bispyridinium compounds bearing a xylene linker and evaluation of their reactivation activity against tabun and paraoxon-inhibited acetylcholinesterase.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2007, v. 22, n. 4, p. 425, doi. 10.1080/14756360601164960

By:

Musilek, Kamil;
Holas, Ondrej;
Kuca, Kamil;
Jun, Daniel;
Dohnal, Vlastimil;
Dolezal, Martin

Publication type:

Article

A comparison of reactivating efficacy of newly developed oximes (K074, K075) and currently available oximes (obidoxime, HI-6) in cyclosarin-and tabun-poisoned rats.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2007, v. 22, n. 3, p. 297, doi. 10.1080/14756360601114361

By:

Kassa, Jiri;
Jun, Daniel;
Kuca, Kamil

Publication type:

Article

New group of xylene linker-containing acetylcholinesterase reactivators as antidotes against the nerve agent cyclosarin.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2006, v. 21, n. 5, p. 515, doi. 10.1080/14756360600741420

By:

Hrabinova, Martina;
Musilek, Kamil;
Jun, Daniel;
Kuca, Kamil

Publication type:

Article

Detoxification of G- and V-series nerve agents by the phosphotriesterase OpdA.

Published in:

Biocatalysis & Biotransformation, 2012, v. 30, n. 2, p. 203, doi. 10.3109/10242422.2012.661724

By:

Wille, Timo;
Scott, Colin;
Thiermann, Horst;
Worek, Franz

Publication type:

Article

Effect of the positron range of F, Ga and I on PET/CT in lung-equivalent materials.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2011, v. 38, n. 5, p. 940, doi. 10.1007/s00259-011-1732-1

By:

Kemerink, Gerrit J.;
Visser, Mariëlle G. W.;
Franssen, Renee;
Beijer, Emiel;
Zamburlini, Mariangela;
Halders, Servé G. E. A.;
Brans, Boudewijn;
Mottaghy, Felix M.;
Teule, Gerrit J. J.

Publication type:

Article

Cellular Pathogenesis of Hepatic Encephalopathy: An Update.

Published in:

Biomolecules (2218-273X), 2023, v. 13, n. 2, p. 396, doi. 10.3390/biom13020396

By:

Lu, Kaihui

Publication type:

Article

Oxaloacetate acid ameliorates paraquat-induced acute lung injury by alleviating oxidative stress and mitochondrial dysfunction.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1029775

By:

Wenwen Li;
Mengxuan Li;
Kaiyuan Chen;
Yahui Tang;
Ran Yin;
Linhua Lan;
Guangliang Hong

Publication type:

Article

Backbone Conformation Shifts in X-ray Structures of Human Acetylcholinesterase upon Covalent Organophosphate Inhibition.

Published in:

Crystals (2073-4352), 2021, v. 11, n. 11, p. 1270, doi. 10.3390/cryst11111270

By:

Luedtke, Stephanie;
Bojo, Celine;
Li, Yunshen;
Luna, Emilio;
Pomar, Bianca;
Radić, Zoran

Publication type:

Article

Structure-activity studies of bispyridinium antinicotinics to select candidates to treat soman intoxication as part of a combined therapy.

Published in:

PLoS ONE, 2025, v. 20, n. 2, p. 1, doi. 10.1371/journal.pone.0318508

By:

Turner, Simon R.;
Timperley, Christopher M.;
Bird, Mike;
Green, A. Christopher;
Price, Matthew E.;
Rice, Helen;
Chad, John E.;
Tattersall, John E. H.

Publication type:

Article

Novel Nerve-Agent Antidote Design Based on Crystallographic and Mass Spectrometric Analyses of Tabun-Conjugated Acetylcholinesterase in Complex with Antidotes.

Published in:

Clinical Pharmacology & Therapeutics, 2007, v. 82, n. 3, p. 282, doi. 10.1038/sj.clpt.6100151

By:

Ekström, F. J.;
Åstot, C.;
Pang, Y.-P.

Publication type:

Article

Efficacious Oxime for Organophosphorus Poisoning: A Minireview.

Published in:

Tropical Journal of Pharmaceutical Research, 2011, v. 10, n. 3, p. 341, doi. 10.4314/tjpr.v10i3.10

By:

Nurulain, Syed M.

Publication type:

Article