Usefulness of dual gradient-echo MR imaging for the prenatal diagnosis of gestational alloimmune disease.

Concejo Iglesias, Paula; Liébana de Rojas, Constanza; Bartolomé Mateos, Alba; Risco Montemayor, Beatriz; Rasero Ponferrada, Miguel; Galindo, Alberto

Gestational alloimmune liver disease (GALD) is a rare and severe illness caused by maternal antibodies against foetal liver. It may cause acute and severe liver failure, or liver disease accompanied by siderosis of extrahepatic tissues. Iron deposits can be confirmed by MRI or by mucosal salivary gland biopsy showing iron staining (Perls stain), although MRI yields a higher sensitivity for such diagnosis (90% versus 60-70%) (Machtei et al. [5]).

MAGNETIC resonance imaging; PRENATAL diagnosis; HYDROPS fetalis; FETAL growth retardation; DIAGNOSIS; IRON ores

Journal of Obstetrics & Gynaecology, 2021, Vol 41, Issue 6, p981

0144-3615

Academic Journal

10.1080/01443615.2020.1798907