We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Synthesis, spectral, thermal analyses, molecular modeling, and antimicrobial activities of Cu(II)-complexes with 1,3,4-oxadiazole Schiff-base derivatives.
- Authors
Khedr, Abdalla M.; El-Wakiel, Nadia A.; Jadon, Sudha; Kumar, Vipin
- Abstract
Seven Cu(II)-complexes with 2-amino-5-substituted aryl-1,3,4-oxadiazole Schiff bases are presented. The donors and possible geometries of the complexes were investigated by elemental and thermal (differential thermal analysis and thermogravimetric analysis) analyses, molar conductance, magnetic moments, IR, 1H-NMR, ESR, UV-Vis, and mass spectra. The ligands are bidentate, coordinating through the nitrogen of azomethine and the nearest nitrogen to it. The results are supported by 3-D molecular modeling of 2 using CS Chem 3-D Ultra Molecular Modeling and Analysis Program. The investigated complexes have been screened for in-vitro antibacterial (Escherichia coli and Staphylococcus aureus) and antifungal (Aspergillus flavus and Candida albicans) activities. The qualitative and quantitative antimicrobial activities prove that the complexes are very active against the tested microorganisms.
- Subjects
COMPLEX compounds synthesis; ANTI-infective agents; COPPER compounds; SCHIFF bases; THERMAL analysis; THERMOGRAVIMETRY; ULTRAVIOLET spectroscopy; METAL complexes; MOLECULAR models
- Publication
Journal of Coordination Chemistry, 2011, Vol 64, Issue 5, p851
- ISSN
0095-8972
- Publication type
Academic Journal
- DOI
10.1080/00958972.2011.557722