Synthesis, structural studies and bio-activity of Mn(II), Co(II), Ni(II), Cu(II) and Zn(II) complexes with p-amino acetophenone salicyloyl hydrazone.

Katiyar, Anshu; Singh, Vinod P.

Complexes of the type [M(pash)Cl] and [M(Hpash)(H2O)SO4] (M=Mn(II), Co(II), Ni(II), Cu(II) and Zn(II); Hpash = p-amino acetophenone salicyloyl hydrazone) have been synthesized and characterized by elemental analyses, molar electrical conductance, magnetic moments, electronic, ESR and IR spectra, thermal studies and X-ray powder diffraction. All the complexes are insoluble in common organic solvents and are non-electrolytes. The magnetic moment values and electronic spectra indicate a square-planar geometry for Co(II), Ni(II) and Cu(II) chloride complexes and spin-free octahedral geometry for the sulfato complexes. The ligand coordinates through >C=N-,-NH2 and a deprotonated enolate group in all the chloro complexes, and through >C=N-, >C=O and-NH2 in the sulfato complexes. Thermal analyses (TGA and DTA) of [Cu(pash)Cl] show a multi-step exothermic decomposition pattern. ESR spectral parameters of Cu(II) complexes in solid state at room temperature suggest the presence of the unpaired electron in dx2-y2. X-ray powder diffraction parameters for [Cu(pash)Cl] and [Ni(Hpash)(H2O)SO4] correspond to tetragonal and orthorhombic crystal lattices, respectively. The complexes show a fair degree of antifungal activity against Aspergillus sp., Stemphylium sp. and Trichoderma sp. and moderate antibacterial activity against E. coli and Clostridium sp.

MANGANESE; COBALT; NICKEL; COPPER; ZINC; ACETOPHENONE; HYDROZONE

Journal of Coordination Chemistry, 2008, Vol 61, Issue 20, p3200

0095-8972

Academic Journal

10.1080/00958970802017646