Works matching Drug metabolism
Results: 5000
Age-related modifications in CYP-dependent drug metabolism: role of stress.
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- Frontiers in Endocrinology, 2023, p. 1, doi. 10.3389/fendo.2023.1143835
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- Article
Cytochrome P450-mediated carbon-carbon bond formation in drug metabolism.
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- Drug Metabolism Reviews, 2025, v. 57, n. 1, p. 51, doi. 10.1080/03602532.2025.2451847
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Drug metabolism and transport mediated the hepatotoxicity of Pleuropterus multiflorus root: a review.
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- Drug Metabolism Reviews, 2024, v. 56, n. 4, p. 349, doi. 10.1080/03602532.2024.2405163
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The alteration of drug metabolism enzymes and pharmacokinetic parameters in nonalcoholic fatty liver disease: current animal models and clinical practice.
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- Drug Metabolism Reviews, 2023, v. 55, n. 3, p. 163, doi. 10.1080/03602532.2023.2202359
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- Article
Aldehyde oxidase mediated drug metabolism: an underpredicted obstacle in drug discovery and development.
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- Drug Metabolism Reviews, 2022, v. 54, n. 4, p. 427, doi. 10.1080/03602532.2022.2144879
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- Article
A transcriptional regulatory network of HNF4α and HNF1α involved in human diseases and drug metabolism.
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- Drug Metabolism Reviews, 2022, v. 54, n. 4, p. 361, doi. 10.1080/03602532.2022.2103146
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- Article
Advances in the study of drug metabolism – symposium report of the 12th Meeting of the International Society for the Study of Xenobiotics (ISSX).
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- Drug Metabolism Reviews, 2020, v. 52, n. 3, p. 395, doi. 10.1080/03602532.2020.1765793
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- Article
Profiles in drug metabolism and toxicology: Richard Tecwyn Williams (1909–1979).
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- Drug Metabolism Reviews, 2015, v. 47, n. 4, p. 401, doi. 10.3109/03602532.2015.1115516
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- Article
Applications of mass spectrometry in drug metabolism: 50 years of progress*.
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- Drug Metabolism Reviews, 2015, v. 47, n. 1, p. 71, doi. 10.3109/03602532.2014.1001029
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- Article
Carbonyl reduction pathways in drug metabolism.
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- Drug Metabolism Reviews, 2014, v. 46, n. 1, p. 96, doi. 10.3109/03602532.2013.853078
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- Article
CYP3A4 and CYP3A5: the crucial roles in clinical drug metabolism and the significant implications of genetic polymorphisms.
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- PeerJ, 2024, p. 1, doi. 10.7717/peerj.18636
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A Biomimetic Human Gut‐on‐a‐Chip for Modeling Drug Metabolism in Intestine.
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- Artificial Organs, 2018, v. 42, n. 12, p. 1196, doi. 10.1111/aor.13163
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- Article
CYP3A-Mediated Carbon–Carbon Bond Cleavages in Drug Metabolism.
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- Biomolecules (2218-273X), 2024, v. 14, n. 9, p. 1125, doi. 10.3390/biom14091125
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Transcriptomic profiling of hepatic tissues for drug metabolism genes in nonalcoholic fatty liver disease: A study of human and animals.
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- Frontiers in Endocrinology, 2023, v. 13, p. 1, doi. 10.3389/fendo.2022.1034494
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- Article
Polymorphisms in drug metabolism genes as a risk factor for first-line anti-tuberculosis drug-induced liver injury.
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- Molecular Biology Reports, 2023, v. 50, n. 3, p. 2893, doi. 10.1007/s11033-022-08158-7
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Impact of individual factors on DNA methylation of drug metabolism genes: A systematic review.
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- Environmental & Molecular Mutagenesis, 2023, v. 64, n. 7, p. 401, doi. 10.1002/em.22567
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- Article
Drug metabolism and drug transport of the 100 most prescribed oral drugs.
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- Basic & Clinical Pharmacology & Toxicology, 2022, v. 131, n. 5, p. 311, doi. 10.1111/bcpt.13780
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- Article
The Combination of Electrochemistry and Microfluidic Technology in Drug Metabolism Studies.
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- ChemistryOpen, 2022, v. 11, n. 12, p. 1, doi. 10.1002/open.202200100
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- Article
Inhibition of drug metabolism by blocking the activation of nuclear receptors by ketoconazole.
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- Oncogene, 2007, v. 26, n. 2, p. 258, doi. 10.1038/sj.onc.1209788
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- Article
Systemy ekspresyjne białek cytochromu P450 w badaniach in vitro metabolizmu leków.
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- Advances in Hygiene & Experimental Medicine / Postepy Higieny i Medycyny Doswiadczalnej, 2011, v. 65, p. 367, doi. 10.5604/17322693.948845
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Sulfotransferase‐mediated phase II drug metabolism prediction of substrates and sites using accessibility and reactivity‐based algorithms.
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- Molecular Informatics, 2024, v. 43, n. 10, p. 1, doi. 10.1002/minf.202400008
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- Article
Changes in the intestinal expression of drug metabolism-related genes in a piglet model of parenteral nutrition.
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- Nutrition & Metabolism, 2022, v. 19, n. 1, p. 1, doi. 10.1186/s12986-022-00654-8
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- Article
Human induced pluripotent stem cell-derived liver-on-a-chip for studying drug metabolism: the challenge of the cytochrome P450 family.
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- Frontiers in Pharmacology, 2023, p. 1, doi. 10.3389/fphar.2023.1223108
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- Article
The Complex Dynamic of Phase I Drug Metabolism in the Early Stages of Doxorubicin Resistance in Breast Cancer Cells.
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- Genes, 2022, v. 13, n. 11, p. 1977, doi. 10.3390/genes13111977
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- Article
Distinct Effects of Inflammation on Cytochrome P450 Regulation and Drug Metabolism: Lessons from Experimental Models and a Potential Role for Pharmacogenetics.
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- Genes, 2020, v. 11, n. 12, p. 1509, doi. 10.3390/genes11121509
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- Article
Utility of Common Marmoset (Callithrix jacchus) Embryonic Stem Cells in Liver Disease Modeling, Tissue Engineering and Drug Metabolism.
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- Genes, 2020, v. 11, n. 7, p. 729, doi. 10.3390/genes11070729
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Utility of spatially-resolved atmospheric pressure surface sampling and ionization techniques as alternatives to mass spectrometric imaging (MSI) in drug metabolism.
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- Xenobiotica, 2011, v. 41, n. 8, p. 720, doi. 10.3109/00498254.2011.587550
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- Article
CYP2C76-mediated species difference in drug metabolism: A comparison of pitavastatin metabolism between monkeys and humans.
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- Xenobiotica, 2007, v. 37, n. 1, p. 30, doi. 10.1080/00498250600968275
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- Article
Compendium of gene expression profiles comprising a baseline model of the human liver drug metabolism transcriptome.
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- Xenobiotica, 2006, v. 36, n. 10/11, p. 938, doi. 10.1080/00498250600861728
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- Article
DNA methylation and histone acetylation changes to cytochrome P450 2E1 regulation in normal aging and impact on rates of drug metabolism in the liver.
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- GeroScience, 2020, v. 42, n. 3, p. 819, doi. 10.1007/s11357-020-00181-5
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Association of drug metabolism gene polymorphisms with toxicities, graft-versus-host disease and survival after HLA-identical sibling hematopoietic stem cell transplantation for patients with leukemia.
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- 2009
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- journal article
Defective Cytochrome P450-Catalysed Drug Metabolism in Niemann-Pick Type C Disease.
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- PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0152007
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Ontogeny and drug metabolism in newborns.
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- Journal of Maternal-Fetal & Neonatal Medicine, 2012, v. 25, p. 75, doi. 10.3109/14767058.2012.715463
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Hepatic drug metabolism in older people with body composition changes.
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- Geriatrics & Gerontology International, 2022, v. 22, n. 5, p. 449, doi. 10.1111/ggi.14380
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Structure-based Drug Metabolism Predictions for Drug Design.
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- Chemical Biology & Drug Design, 2010, v. 75, n. 1, p. 3, doi. 10.1111/j.1747-0285.2009.00899.x
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Effects of meal composition and meal timing on the expression of genes involved in hepatic drug metabolism in rats.
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- PLoS ONE, 2017, v. 12, n. 10, p. 1, doi. 10.1371/journal.pone.0185520
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- Article
The gene expression profile of a drug metabolism system and signal transduction pathways in the liver of mice treated with tert-butylhydroquinone or 3-(3'-tert-butyl-4'-hydroxyphenyl)propylthiosulfonate of sodium.
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- PLoS ONE, 2017, v. 12, n. 5, p. 1, doi. 10.1371/journal.pone.0176939
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Engineering HepG2 spheroids with injectable fiber fragments as predictable models for drug metabolism and tumor infiltration.
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- Journal of Biomedical Materials Research, Part B: Applied Biomaterials, 2020, v. 108, n. 8, p. 3331, doi. 10.1002/jbm.b.34669
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- Article
Cytochrome P450 Enzymes and Drug Metabolism in Humans.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 23, p. 12808, doi. 10.3390/ijms222312808
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Study of Drug Metabolism by Xanthine Oxidase.
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- International Journal of Molecular Sciences, 2012, v. 13, n. 4, p. 4873, doi. 10.3390/ijms13044873
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- Article
Induction of Liver Size Reduction in Zebrafish Larvae by the Emerging Synthetic Cannabinoid 4F-MDMB-BINACA and Its Impact on Drug Metabolism.
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- Molecules, 2022, v. 27, n. 4, p. 1290, doi. 10.3390/molecules27041290
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- Article
Drug Administration Routes Impact the Metabolism of a Synthetic Cannabinoid in the Zebrafish Larvae Model.
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- Molecules, 2020, v. 25, n. 19, p. 4474, doi. 10.3390/molecules25194474
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- Article
Inflammatory signaling on cytochrome P450-mediated drug metabolism in hepatocytes.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1043836
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- Article
Butyrate Treatment of DSS-Induced Ulcerative Colitis Affects the Hepatic Drug Metabolism in Mice.
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- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.936013
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Artificial Intelligence in Drug Metabolism and Excretion Prediction: Recent Advances, Challenges, and Future Perspectives.
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- Pharmaceutics, 2023, v. 15, n. 4, p. 1260, doi. 10.3390/pharmaceutics15041260
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Analysis for drug metabolism-related prognostic subtypes and gene signature in liver cancer.
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- Genes & Genetic Systems, 2022, v. 97, n. 6, p. 271, doi. 10.1266/ggs.22-00093
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Innovative approaches and recent advances in the study of ontogeny of drug metabolism and transport.
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- British Journal of Clinical Pharmacology, 2022, v. 88, n. 10, p. 4285, doi. 10.1111/bcp.14534
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Drug metabolism in severe chronic obstructive pulmonary disease: A phenotyping cocktail study.
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- British Journal of Clinical Pharmacology, 2021, v. 87, n. 11, p. 4397, doi. 10.1111/bcp.14862
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Drug metabolism.
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- Resonance: Journal of Science Education, 2014, v. 19, n. 3, p. 259, doi. 10.1007/s12045-014-0031-0
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Considerations and recent advances in QSAR models for cytochrome P450-mediated drug metabolism prediction.
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- Journal of Computer-Aided Molecular Design, 2008, v. 22, n. 11, p. 843, doi. 10.1007/s10822-008-9225-4
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