Works matching DE "PYRIDAZINONES"

Results: 139

Histological assessment of liver and stomach damage caused by pyridazinone derivative antidepressant agents.

Published in:

Biotechnic & Histochemistry, 2022, v. 97, n. 5, p. 355, doi. 10.1080/10520295.2021.1999499

By:

Özdemir, Zeynep;
Karakurt, Arzu;
Taşlidere, Elif;
Vardi, Nigar;
Alagöz, Mehmet Abdullah;
Parlakpinar, Hakan;
Uslu, Harun;
Bağ, Harika Gözükara

Publication type:

Article

Direct Asymmetric α‐Selective Mannich Reaction of β,γ‐Unsaturated Ketones with Cyclic α‐Imino Ester: Divergent Synthesis of Cyclocanaline and Tetrahydro Pyridazinone Derivatives.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 16, p. 5130, doi. 10.1002/chem.202100284

By:

Geng, Yu‐Huan;
Hua, Yuan‐Zhao;
Jia, Shi‐Kun;
Wang, Min‐Can

Publication type:

Article

Efficient Synthesis using One-Pot Method and In Silico Analysis of Pyridazinone Derivatives as Inhibitor for Aldose Reductase Enzymes.

Published in:

Trends in Sciences, 2025, v. 22, n. 4, p. 1, doi. 10.48048/tis.2025.9396

By:

Fatisa, Yuni;
Herfindo, Noval;
Aisyah, Fadila;
Teruna, Hilwan Yuda;
Jasril, Jasril;
Zamri, Adel;
Frimayanti, Neni

Publication type:

Article

Synthesis and Biological Activity of New [1,3]Thiazolo[4,5-d]pyridazin-4(5H)-ones.

Published in:

Scientia Pharmaceutica, 2016, v. 84, n. 2, p. 255, doi. 10.3797/scipharm.1505-16

By:

DEMCHENKO, Anatoly;
BOBKOVA, Ludmila;
YADLOVSKIY, Oleh;
BUCHTIAROVA, Tatiana;
DEMCHENKO, Sergey

Publication type:

Article

A new compound of thiophenylated pyridazinone IMB5043 showing potent antitumor efficacy through ATM-Chk2 pathway.

Published in:

PLoS ONE, 2018, v. 13, n. 2, p. 1, doi. 10.1371/journal.pone.0191984

By:

Gong, Jianhua;
Zheng, Yanbo;
Wang, Ying;
Sheng, Weijin;
Li, Yi;
Liu, Xiujun;
Si, Shuyi;
Shao, Rongguang;
Zhen, Yongsu

Publication type:

Article

Rational Design of a Near-Infrared Fluorescent Probe Based on a Pyridazinone Scaffold.

Published in:

European Journal of Organic Chemistry, 2017, v. 2017, n. 22, p. 3274, doi. 10.1002/ejoc.201700355

By:

Zhou, Tongliang;
Yang, Lingfei;
Liang, Lei;
Liu, Hui;
Zhu, Yuanjun;
Shui, Mengyang;
Yuan, Lan;
Xu, Fengrong;
Niu, Yan;
Wang, Chao;
Xu, Ping

Publication type:

Article

The Generation of a Library of Bromodomain-Containing Protein Modulators Expedited by Continuous Flow Synthesis.

Published in:

European Journal of Organic Chemistry, 2016, v. 2016, n. 11, p. 2000, doi. 10.1002/ejoc.201600222

By:

Filipponi, Paolo;
Baxendale, Ian R.

Publication type:

Article

Ureido-Pyridazinone Derivatives: Insights into the Structural and Conformational Properties for STAT3 Inhibition.

Published in:

European Journal of Organic Chemistry, 2015, v. 2015, n. 22, p. 4907, doi. 10.1002/ejoc.201500599

By:

Meneghetti, Fiorella;
Villa, Stefania;
Masciocchi, Daniela;
Barlocco, Daniela;
Toma, Lucio;
Han, Dong‐Cho;
Kwon, Byoung‐Mog;
Ogo, Naohisa;
Asai, Akira;
Legnani, Laura;
Gelain, Arianna

Publication type:

Article

Ruthenium-Catalyzed Switchable N-H/C-H Alkenylation of 6-Phenyl(dihydro)pyridazinones with Alkynes.

Published in:

European Journal of Organic Chemistry, 2014, v. 2014, n. 31, p. 6863, doi. 10.1002/ejoc.201402986

By:

Wang, Wei;
Liang, Lei;
Xu, Fengrong;
Huang, Wenjie;
Niu, Yan;
Sun, Qi;
Xu, Ping

Publication type:

Article

Copper-Catalyzed Aerobic Dehydrogenation of C-C to C=C Bonds in the Synthesis of Pyridazinones.

Published in:

European Journal of Organic Chemistry, 2013, v. 2013, n. 27, p. 6130, doi. 10.1002/ejoc.201300640

By:

Liang, Lei;
Yang, Guanyu;
Xu, Fengrong;
Niu, Yan;
Sun, Qi;
Xu, Ping

Publication type:

Article

Novel Method for Preparing Fluorination Reagent and Its Application to Synthesis of Fluoropyridazinones.

Published in:

Synthetic Communications, 2010, v. 40, n. 4, p. 535, doi. 10.1080/00397910903003466

By:

Pei, Wen;
Yang, Wei

Publication type:

Article

Triton B-Mediated Mild, Convenient, and Efficient Method for the Selective Alkylation of Cyclic Secondary Amines and Thiols.

Published in:

Synthetic Communications, 2009, v. 39, n. 13, p. 2297, doi. 10.1080/00397910802654740

By:

Meshram, H. M.;
Reddy, B. Chennakesava;
Goud, P. Ramesh

Publication type:

Article

Novel Pyridazine Fused Heterocyclic System: A New Route for the Synthesis of 2‐Alkyl/Aryl[1,3,4]Thiadiazole[2′,3′:2,3] Imidazo[4,5‐ d ]Pyridazin‐8(7 H )‐One.

Published in:

Synthetic Communications, 2006, v. 36, n. 13, p. 1837, doi. 10.1080/00397910600602511

By:

Kolavi, Gundurao;
Hegde, Vinayak;
Khazi, ImtiyazAhmed

Publication type:

Article

One-Pot Synthesis of Pyridazino[1,4]oxazin-3-ones.

Published in:

Synthetic Communications, 2004, v. 34, n. 8, p. 1399, doi. 10.1081/SCC-120030689

By:

Ma, Chen;
Cho, Su‐Dong;
Falck, J.R.;
Shin, Dong‐Soo

Publication type:

Article

Zeolite-HY Catalyzed Synthesis of 1,8-Naphthyridinyl-3(2H)-pyridazinones in Dry Media Under Microwave Irradiation.

Published in:

Synthetic Communications, 2003, v. 33, n. 7, p. 1067, doi. 10.1081/SCC-120017127

By:

Mogilaiah, K.;
Vasudeva Reddy, N.

Publication type:

Article

PYRIDAZINE DERIVATIVES. XXIV. EFFICIENT N-METHYLATION OF DIVERSELY SUBSTITUTED 3(2H)-PYRIDAZINONES USING N,N-DIMETHYLFORMAMIDE DIMETHYLACETAL.

Published in:

Synthetic Communications, 2002, v. 32, n. 11, p. 1675, doi. 10.1081/SCC-120004258

By:

Sotelo, Eddy;
Raviña, Enrique

Publication type:

Article

Development of Pyridazinone Chemotypes Targeting the PDEδ Prenyl Binding Site.

Published in:

Chemistry - A European Journal, 2017, v. 23, n. 25, p. 6083, doi. 10.1002/chem.201603222

By:

Murarka, Sandip;
Martín‐Gago, Pablo;
Schultz‐Fademrecht, Carsten;
Al Saabi, Alaa;
Baumann, Matthias;
Fansa, Eyad K.;
Ismail, Shehab;
Nussbaumer, Peter;
Wittinghofer, Alfred;
Waldmann, Herbert

Publication type:

Article

Rational Design of Fluorescent Phthalazinone Derivatives for One- and Two-Photon Imaging.

Published in:

Chemistry - A European Journal, 2016, v. 22, n. 35, p. 12363, doi. 10.1002/chem.201601499

By:

Yang, Lingfei;
Zhu, Yuanjun;
Shui, Mengyang;
Zhou, Tongliang;
Cai, Yuanbo;
Wang, Wei;
Xu, Fengrong;
Niu, Yan;
Wang, Chao;
Zhang, Jun‐Long;
Xu, Ping;
Yuan, Lan;
Liang, Lei

Publication type:

Article

Copper(I)-Catalyzed Synthesis of Chlorinated Tetrahydropyridazin-3-ones and 1,2-Diazepan-3-ones from N-Allyl- N′-trichloroacetylhydrazines.

Published in:

Advanced Synthesis & Catalysis, 2016, v. 358, n. 2, p. 276, doi. 10.1002/adsc.201500876

By:

Ram, Ram N.;
Soni, Vineet Kumar

Publication type:

Article

Synthesis and bioevaluation of 4-chloro-2- tert-butyl-5-[2-[[1-[2-[18F]fluroethyl]-1 H-1,2,3-triazol-4-yl]methyl]phenylmethoxy]-3(2 H)-pyridazinone as potential myocardial perfusion imaging agent with PET.

Published in:

Journal of Labelled Compounds & Radiopharmaceuticals, 2015, v. 58, n. 8, p. 349, doi. 10.1002/jlcr.3310

By:

Mou, Tiantian;
Zhao, Zuoquan;
You, Linyi;
Wang, Qian;
Fang, Wei;
Lu, Jie;
Peng, Cheng;
Zhang, Xianzhong

Publication type:

Article

Synthesis and Antibacterial Activity of Some Glucosyl- and Ribosyl-Pyridazin-3-ones.

Published in:

Nucleosides, Nucleotides & Nucleic Acids, 2009, v. 28, n. 3, p. 184, doi. 10.1080/15257770902831011

By:

El-Sayed, H.A.;
Moustafa, A.H.;
Haikal, A.Z.;
El-Ashry, E.S. H.

Publication type:

Article

Synthesis and antimicrobial investigation of some 5H-pyridazino[4,5-b]indoles.

Published in:

Turkish Journal of Chemistry, 2013, v. 37, n. 2, p. 271, doi. 10.3906/kim-1210-22

By:

AVAN, İlker;
GÜVEN, Alaattin;
GÜVEN, Kıymet

Publication type:

Article

Synthesis of antipyrine/pyridazinone hybrids and investigation of their in vivo analgesic and anti-inflammatory activities.

Published in:

Turkish Journal of Chemistry, 2012, v. 36, n. 5, p. 734, doi. 10.3906/kim-1111-29

By:

BAYTAŞ, Sultan;
İNCELER, Nazan;
MAVANEH, Khatereh Fattahpour;
ULUDAĞ, Mecit Örhan;
ABACIOĞLU, Nurettin;
GOKÇE, Mehtap

Publication type:

Article

Synthesis and in vitro antimycobacterial activities of novel 6-substituted-3 (2H)-pyridazinone-2-acetyl-2-(substituted/nonsubstituted acetophenone) hydrazone.

Published in:

Turkish Journal of Chemistry, 2011, v. 35, n. 2, p. 331, doi. 10.3906/kim-1009-63

By:

UTKU, Semra;
GÖKÇE, Mehtap;
ASLAN, Gönül;
BAYRAM, Gül;
ÜLGER, Mahmut;
EMEKDAŞ, Gürol;
ŞAHİN, M. Fethi

Publication type:

Article

Synthesis and Antimicrobial Activity of Some 3(2H)-Pyridazinone and 1(2H)-Phthalazinone Derivatives.

Published in:

Turkish Journal of Chemistry, 2008, v. 32, n. 4, p. 469

By:

Doğruer, Deniz S.;
Önkol, Tijen;
Özkan, Semiha;
Özgen, Selda;
Şahın, M. Fethi

Publication type:

Article

A New Method for the Preparation of Pyridazine Systems: Experimental Data and Semiempirical PM3 Calculations.

Published in:

Turkish Journal of Chemistry, 2006, v. 30, n. 6, p. 691

By:

Ünal, Dilek;
Saripinar, Emin;
Akçamur, Yunus

Publication type:

Article

Synthesis and Some Reactions of 4-Benzoyl-5-Phenyl-1-(2,4,6-Trichloro Phenyl)-1H-Pyrazole-3-Carboxylic Acid.

Published in:

Turkish Journal of Chemistry, 2004, v. 28, n. 2, p. 149

By:

Sener, Ahmet;
Bildirici, Ishak

Publication type:

Article

On the conditions for enhanced transport through molecular junctions based on metal centres ligated by pairs of pyridazino-derived ligands.

Published in:

Molecular Physics, 2010, v. 108, n. 19/20, p. 2591, doi. 10.1080/00268976.2010.514303

By:

Bei Ding;
Washington, Victoria;
Dunietz, Barry D.

Publication type:

Article

Cover Feature: Isomerisation of Vinyl Sulfones for the Stereoselective Synthesis of Vinyl Azides (Eur. J. Org. Chem. 43/2020).

Published in:

European Journal of Organic Chemistry, 2020, v. 2020, n. 43, p. 6674, doi. 10.1002/ejoc.202001290

By:

Collins, Niall;
Connon, Robert;
Sánchez‐Sanz, Goar;
Evans, Paul

Publication type:

Article

NMR structure-based optimization of Staphylococcus aureus sortase A pyridazinone inhibitors.

Published in:

2017

By:

Chan, Albert H.;
Yi, Sung Wook;
Weiner, Ethan M.;
Amer, Brendan R.;
Sue, Christopher K.;
Wereszczynski, Jeff;
Dillen, Carly A.;
Senese, Silvia;
Torres, Jorge Z.;
McCammon, J. Andrew;
Miller, Lloyd S.;
Jung, Michael E.;
Clubb, Robert T.

Publication type:

Editorial

Synthesis of Pyridazinones through the Copper(I)-Catalyzed Multicomponent Reaction of Aldehydes, Hydrazines, and Alkynylesters.

Published in:

Chemistry - A European Journal, 2014, v. 20, n. 39, p. 12663, doi. 10.1002/chem.201403873

By:

Mantovani, Anderson C.;
Goulart, Tales A. C.;
Back, Davi F.;
Zeni, Gilson

Publication type:

Article

Rational Design, Green Synthesis, and Initial Evaluation of a Series of Full-Color Tunable Fluorescent Dyes Enabled by the Copper-Catalyzed N-Arylation of 6-Phenyl Pyridazinones and Their Application in Cell Imaging.

Published in:

Chemistry - A European Journal, 2013, v. 19, n. 41, p. 13774, doi. 10.1002/chem.201302495

By:

Liang, Lei;
Wang, Wei;
Wu, Jun;
Xu, Fengrong;
Niu, Yan;
Xu, Bo;
Xu, Ping

Publication type:

Article

Synthesis and Characterization of Novel Compounds Derived From 6-methyl-2,6 dihydro[1,2,4-triazino[4,3-b] indazol-3(4H)-one.

Published in:

International Journal of Pharmaceutical Research (09752366), 2020, p. 1504, doi. 10.31838/ijpr/2020.SP1.233

By:

AL-SURAIFY, SAJIDA MUNADI TH.

Publication type:

Article

SYNTHESIS AND ANALGESIC ACTIVITY OF 6-(M-NITROPHENYL)-4-SUBSTITUTED BENZYLIDENE-4,5- DIHYDROPYRIDAZIN-3(2H)-ONE DERIVATIVES.

Published in:

Indonesian Journal of Pharmacy / Majalah Farmasi Indonesia, 2012, v. 23, n. 4, p. 254

By:

Asif, Mohammad

Publication type:

Article

Ribosome-mediated biosynthesis of pyridazinone oligomers in vitro.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33701-2

By:

Lee, Joongoo;
Coronado, Jaime N.;
Cho, Namjin;
Lim, Jongdoo;
Hosford, Brandon M.;
Seo, Sangwon;
Kim, Do Soon;
Kofman, Camila;
Moore, Jeffrey S.;
Ellington, Andrew D.;
Anslyn, Eric V.;
Jewett, Michael C.

Publication type:

Article

Vasodilation and Mechanoenergetic Inefficiency Dominates the Effect of the "Ca[sup 2+]-sensitizer" MCI-154 in Intact Pigs.

Published in:

Scandinavian Cardiovascular Journal, 2002, v. 36, n. 3, p. 172, doi. 10.1080/cdv.36.3.172.179

By:

Korvald, Christian;
Nordhaug, Dag Ole;
Steensrud, Tor;
Aghajani, Ebrahim;
Myrmel, Truls

Publication type:

Article

Synthesis of Diphenyl Pyridazinone-based flexible system for conformational studies through weak noncovalent interactions: Application in DNA binding.

Published in:

Journal of Chemical Sciences, 2016, v. 128, n. 4, p. 555, doi. 10.1007/s12039-016-1059-3

By:

KUMAR, RANJEET;
SINGH, PRAVEEN;
GAURAV, ARCHANA;
YADAV, PRATIMA;
KHANNA, RANJANA;
TEWARI, ASHISH

Publication type:

Article

QSAR and pharmacophore analysis on pyridazinone derivatives as acetylcholinesterase inhibitors.

Published in:

Annals of Medical of Research, 2020, v. 27, n. 1, p. 266, doi. 10.5455/annalsmedres.2019.09.510

By:

Alagoz, Mehmet Abdullah;
Ozdemir, Zeynep;
Zenni, Yaren Nur;
Yilmaz, Tuba;
Onkol, Tijen

Publication type:

Article

Synthesis and herbicidal activity of novel α,α,α-trifluoro-m-tolyI pyridazinone derivatives.

Published in:

Pest Management Science, 2006, v. 62, n. 6, p. 522, doi. 10.1002/ps.1195

By:

Han Xu;
Xiao-Mao Zou;
You-Quan Zhu;
Bin Liu;
Han-Lin Tao;
Xu-Hong Hu;
Hai-Bin Song;
Fang-Zhong Hu;
Yong Wang;
Hua-Zheng Yang

Publication type:

Article

Analyzing of some druggable properties of hydrazono-pyridazinones.

Published in:

Bioorganic & Medicinal Chemistry Reports, 2018, v. 1, n. 1, p. 29, doi. 10.25135/bmcr.10.18.12.1104

By:

Kuzu, Burak;
Menges, Nurettin

Publication type:

Article

Green, Practical and Scalable Multicomponent Reaction for the Synthesis of Amides and Pyridazinones from Arenes Using L-Proline Functionalized Silicapropyl Modified Nanomagnetic as a Heterogeneous Bronsted Acid Catalyst.

Published in:

Polycyclic Aromatic Compounds, 2022, v. 42, n. 3, p. 690, doi. 10.1080/10406638.2020.1749091

By:

Fekri, Leila Zare;
Feshalami, Marjan Farjood

Publication type:

Article

SiO2-BiCl3 as Heterogeneous Catalyzed Synthesis of 6-Methyl-2-aryl-4,5-dihydropyridazin-3(2H)-one Derivatives.

Published in:

Polycyclic Aromatic Compounds, 2020, v. 40, n. 5, p. 1501, doi. 10.1080/10406638.2018.1557708

By:

Hote, Baliram S.;
Sawant, Ajay S.;
Sawant, Sanjay S.

Publication type:

Article

Identification of new 4-(6-oxopyridazin-1-yl)benzenesulfonamides as multi-target anti-inflammatory agents targeting carbonic anhydrase, COX-2 and 5-LOX enzymes: synthesis, biological evaluations and modelling insights.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2201407

By:

Badawi, Waleed A.;
Rashed, Mahmoud;
Nocentini, Alessio;
Bonardi, Alessandro;
Abd-Alhaseeb, Mohammad M.;
Al-Rashood, Sara T.;
Veerakanellore, Giri Babu;
Majrashi, Taghreed A.;
Elkaeed, Eslam B.;
Elgendy, Bahaa;
Gratteri, Paola;
Supuran, Claudiu T.;
Eldehna, Wagdy M.;
Elagawany, Mohamed

Publication type:

Article

Utility of novel 2-furanones in synthesis of other heterocyclic compounds having anti-inflammatory activity with dual COX2/LOX inhibition.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 977, doi. 10.1080/14756366.2021.1908277

By:

Abd El-Hameed, Rania H.;
Mahgoub, Shahenda;
El-Shanbaky, Hend M.;
Mohamed, Mosaad S.;
Ali, Sahar A.

Publication type:

Article

Design and synthesis of pyridazinone-substituted benzenesulphonylurea derivatives as anti-hyperglycaemic agents and inhibitors of aldose reductase – an enzyme embroiled in diabetic complications.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 6, p. 1415, doi. 10.3109/14756366.2016.1142986

By:

Yaseen, Raed;
Pushpalatha, H.;
Reddy, G. Bhanuprakash;
Ismael, Ameer;
Ahmed, Ayad;
Dheyaa, Alhamza;
Ovais, Syed;
Rathore, Pooja;
Samim, Mohammed;
Akthar, Mymoona;
Sharma, Kalicharan;
Shafi, Syed;
Singh, Surender;
Javed, Kalim

Publication type:

Article

Design, synthesis and antihypertensive screening of novel pyridazine substituted s-triazin-2-imine/one/thione derivatives.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2013, v. 28, n. 3, p. 552, doi. 10.3109/14756366.2012.656623

By:

Mishra, Ravinesh;
Siddiqui, Anees A.;
Husain, Asif;
Rashid, Mohd.;
Goda, Chirag

Publication type:

Article

Synthesis and biological evaluation of some novel sulfamoylphenyl-pyridazinone as anti-inflammatory agents (Part-II**).

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2012, v. 27, n. 1, p. 92, doi. 10.3109/14756366.2011.577036

By:

Bashir, Rafia;
Yaseen, Shafiya;
Ovais, Syed;
Ahmad, Shamim;
Hamid, Hinna;
Alam, M.S.;
Samim, Mohammad;
Javed, Kalim

Publication type:

Article

Synthesis and biological evaluation of some new pyridazinone derivatives.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2011, v. 26, n. 5, p. 742, doi. 10.3109/14756366.2010.548810

By:

Husain, Asif;
Drabu, Sushma;
Kumar, Nitin;
Alam, M. Mumtaz;
Ahmad, Aftab

Publication type:

Article

Synthesis of pyrrolo[2,3-d]pyridazinones as potent, subtype selective PDE4 inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2007, v. 22, n. 3, p. 309, doi. 10.1080/14756360601114700

By:

Giovannoni, Maria P.;
Cesari, Nicoletta;
Graziano, Alessia;
Vergelli, Claudia;
Biancalani, Claudio;
Biagini, Pierfrancesco;
Piaz, Vittorio Dal

Publication type:

Article

Synthesis, Molecular Docking and Potential Antioxidant Activity of Di/Trisubstituted Pyridazinone Derivatives.

Published in:

Journal of the Chinese Chemical Society, 2016, v. 63, n. 9, p. 739, doi. 10.1002/jccs.201600051

By:

Khokra, Sukhbir Lal;
Khan, Shah Alam;
Thakur, Pramila;
Chowdhary, Deepika;
Ahmad, Aftab;
Husain, Asif

Publication type:

Article