Sexual science will advance the most in the next decade if it develops synergy with neighboring social and biological sciences, and with the humanities as well. Here I explore recent advances in primatology, behavioral neuroscience, and emotion research; and methodological advances in sex research, including interviewing by talking computers, combining qualitative and quantitative methods, and sexual diaries. Theory from the humanities using the metaphor of geography and borderland encounters is also reviewed. Finally, new technologies such as fMRI present new opportunities for research, and the new reproductive technologies create important new questions to answer.