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Title

Determination of Sample Concentrations by PULCON NMR Spectroscopy.

Authors

Mak, Jeffrey Y. W.

Abstract

PULCON (Pulse Length-Based Concentration Determination) is a powerful, versatile, non-invasive, and accurate technique for measuring solution concentrations via routine NMR spectroscopy. It is particularly useful for preparing accurate solutions of compounds for biological assays, and avoids weight-based errors caused by contaminants (e.g. moisture). This article provides an introductory guide for biological and medicinal chemists, and highlights the diversity of applications.

Subjects

BIOCHEMISTS; BIOLOGICAL assay; NUCLEAR magnetic resonance spectroscopy; ANALYTICAL chemistry; BIOCHEMISTRY; PHARMACEUTICAL chemistry

Publication

Australian Journal of Chemistry, 2022, Vol 75, Issue 2, p160

ISSN

0004-9425

Publication type

Academic Journal

DOI

10.1071/CH21149