Works matching DE "CATHEPSINS"

Results: 712

D3R Grand Challenge 3: blind prediction of protein-ligand poses and affinity rankings.

Published in:

Journal of Computer-Aided Molecular Design, 2019, v. 33, n. 1, p. 1, doi. 10.1007/s10822-018-0180-4

By:

Gaieb, Zied;
Parks, Conor D.;
Chiu, Michael;
Yang, Huanwang;
Shao, Chenghua;
Walters, W. Patrick;
Lambert, Millard H.;
Nevins, Neysa;
Bembenek, Scott D.;
Ameriks, Michael K.;
Mirzadegan, Tara;
Burley, Stephen K.;
Amaro, Rommie E.;
Gilson, Michael K.

Publication type:

Article

Monte Carlo on the manifold and MD refinement for binding pose prediction of protein-ligand complexes: 2017 D3R Grand Challenge.

Published in:

Journal of Computer-Aided Molecular Design, 2019, v. 33, n. 1, p. 119, doi. 10.1007/s10822-018-0176-0

By:

Ignatov, Mikhail;
Liu, Cong;
Alekseenko, Andrey;
Sun, Zhuyezi;
Padhorny, Dzmitry;
Kotelnikov, Sergei;
Kazennov, Andrey;
Grebenkin, Ivan;
Kholodov, Yaroslav;
Kolosvari, Istvan;
Perez, Alberto;
Dill, Ken;
Kozakov, Dima

Publication type:

Article

Calculate protein-ligand binding affinities with the extended linear interaction energy method: application on the Cathepsin S set in the D3R Grand Challenge 3.

Published in:

Journal of Computer-Aided Molecular Design, 2019, v. 33, n. 1, p. 105, doi. 10.1007/s10822-018-0162-6

By:

He, Xibing;
Man, Viet H.;
Ji, Beihong;
Xie, Xiang-Qun;
Wang, Junmei

Publication type:

Article

Protein-ligand pose and affinity prediction: Lessons from D3R Grand Challenge 3.

Published in:

Journal of Computer-Aided Molecular Design, 2019, v. 33, n. 1, p. 83, doi. 10.1007/s10822-018-0148-4

By:

Koukos, Panagiotis I.;
Xue, Li C.;
Bonvin, Alexandre M. J. J.

Publication type:

Article

Blinded evaluation of cathepsin S inhibitors from the D3RGC3 dataset using molecular docking and free energy calculations.

Published in:

Journal of Computer-Aided Molecular Design, 2019, v. 33, n. 1, p. 93, doi. 10.1007/s10822-018-0161-7

By:

Chaput, Ludovic;
Selwa, Edithe;
Elisée, Eddy;
Iorga, Bogdan I.

Publication type:

Article

Convolutional neural network scoring and minimization in the D3R 2017 community challenge.

Published in:

Journal of Computer-Aided Molecular Design, 2019, v. 33, n. 1, p. 19, doi. 10.1007/s10822-018-0133-y

By:

Sunseri, Jocelyn;
King, Jonathan E.;
Francoeur, Paul G.;
Koes, David Ryan

Publication type:

Article

Molecular dynamics simulation of halogen bonding mimics experimental data for cathepsin L inhibition.

Published in:

Journal of Computer-Aided Molecular Design, 2015, v. 29, n. 1, p. 37, doi. 10.1007/s10822-014-9802-7

By:

Celis-Barros, Cristian;
Saavedra-Rivas, Leslie;
Salgado, J.;
Cassels, Bruce;
Zapata-Torres, Gerald

Publication type:

Article

Proteolytic chemokine cleavage as a regulator of lymphocytic infiltration in solid tumors.

Published in:

Cancer & Metastasis Reviews, 2019, v. 38, n. 3, p. 417, doi. 10.1007/s10555-019-09807-3

By:

Bronger, Holger;
Magdolen, Viktor;
Goettig, Peter;
Dreyer, Tobias

Publication type:

Article

A Proposal for the Evolution of Cathepsin and Silicatein in Sponges.

Published in:

Journal of Molecular Evolution, 2015, v. 80, n. 5/6, p. 278, doi. 10.1007/s00239-015-9682-z

By:

Riesgo, Ana;
Maldonado, Manuel;
López-Legentil, Susanna;
Giribet, Gonzalo

Publication type:

Article

A Mild Inhibition of Cathepsin K Paradoxically Stimulates the Resorptive Activity of Osteoclasts in Culture.

Published in:

2019

By:

Pirapaharan, Dinisha Cyril;
Søe, Kent;
Panwar, Preety;
Madsen, Jonna Skov;
Bergmann, Marianne Lerbæk;
Overgaard, Martin;
Brömme, Dieter;
Delaisse, Jean-Marie

Publication type:

journal article

Development of a New Immunoassay for Human Cathepsin K-Generated Periostin Fragments as a Serum Biomarker for Cortical Bone.

Published in:

2017

By:

Garnero, Patrick;
Bonnet, Nicolas;
Ferrari, Serge;
Ferrari, Serge L

Publication type:

journal article

Cathepsin K Inhibition: A New Mechanism for the Treatment of Osteoporosis.

Published in:

2016

By:

Duong, Le;
Leung, Albert;
Langdahl, Bente;
Duong, Le T;
Leung, Albert T

Publication type:

journal article

A Mutation in CTSK Gene in an Autosomal Recessive Pycnodysostosis Family of Chinese Origin.

Published in:

Calcified Tissue International, 2015, v. 96, n. 5, p. 373, doi. 10.1007/s00223-015-9963-y

By:

Huang, Xianglan;
Qi, Xuan;
Li, Mei;
Wang, Ou;
Jiang, Yan;
Xing, Xiaoping;
Hu, Ying;
Xia, Weibo

Publication type:

Article

The Bone Resorption Inhibitors Odanacatib and Alendronate Affect Post-Osteoclastic Events Differently in Ovariectomized Rabbits.

Published in:

Calcified Tissue International, 2014, v. 94, n. 2, p. 212, doi. 10.1007/s00223-013-9800-0

By:

Jensen, Pia;
Andersen, Thomas;
Pennypacker, Brenda;
Duong, Le;
Delaissé, Jean-Marie

Publication type:

Article

Cathepsin K Preferentially Solubilizes Matured Bone Matrix.

Published in:

Calcified Tissue International, 2012, v. 91, n. 1, p. 32, doi. 10.1007/s00223-012-9604-7

By:

Borel, Olivier;
Gineyts, Evelyne;
Bertholon, Cindy;
Garnero, Patrick

Publication type:

Article

Proteolytic activation of the epithelial sodium channel (ENaC) by the cysteine protease cathepsin-S.

Published in:

Pflügers Archiv: European Journal of Physiology, 2012, v. 464, n. 4, p. 353, doi. 10.1007/s00424-012-1138-3

By:

Haerteis, Silke;
Krappitz, Matteus;
Bertog, Marko;
Krappitz, Annabel;
Baraznenok, Vera;
Henderson, Ian;
Lindström, Erik;
Murphy, Jane;
Bunnett, Nigel;
Korbmacher, Christoph

Publication type:

Article

Cancer: Killing from the inside.

Published in:

Nature, 2013, v. 502, n. 7471, p. 312, doi. 10.1038/nature12692

By:

Saftig, Paul;
Sandhoff, Konrad

Publication type:

Article

Expression, Intracellular Localization, and Maturation of Cysteine Cathepsins in Renal Embryonic and Cancer Cell Lines.

Published in:

Biochemistry (00062979), 2023, v. 88, n. 7, p. 1034, doi. 10.1134/S0006297923070143

By:

Frolova, Anastasia S.;
Tikhomirova, Natalia K.;
Kireev, Igor I.;
Zernii, Evgeni Yu.;
Parodi, Alessandro;
Ivanov, Konstantin I.;
Zamyatnin Jr., Andrey A.

Publication type:

Article

Isofraxidin Inhibits Receptor Activator of Nuclear Factor-κB Ligand–Induced Osteoclastogenesis in Bone Marrow–Derived Macrophages Isolated from Sprague–Dawley Rats by Regulating NF-κB/NFATc1 and Akt/NFATc1 Signaling Pathways.

Published in:

Cell Transplantation, 2021, v. 30, p. 1, doi. 10.1177/0963689721990321

By:

Wang, Wei;
Wang, Bo

Publication type:

Article

Inhibitory effects of specific combination of natural compounds against SARS-CoV-2 and its Alpha, Beta, Gamma, Delta, Kappa, and Mu variants.

Published in:

European Journal of Microbiology & Immunology, 2021, v. 11, n. 4, p. 87, doi. 10.1556/1886.2021.00022

By:

GOC, ANNA;
NIEDZWIECKI, ALEKSANDRA;
IVANOV, VADIM;
IVANOVA, SVETLANA;
RATH, MATTHIAS

Publication type:

Article

BRCA1 loss activates cathepsin L-mediated degradation of 53BP1 in breast cancer cells.

Published in:

Journal of Cell Biology, 2013, v. 200, n. 2, p. 187, doi. 10.1083/jcb.201204053

By:

Grotsky, David A.;
Gonzalez-Suarezy, Ignacio;
Novell, Anna;
Neumann, Martin A.;
Yaddanapudi, Sree C.;
Croke, Monica;
Martinez-Alonso, Montserrat;
Redwood, Abena B.;
Ortega-Martinez, Sylvia;
Feng, Zhihui;
Lerma, Enrique;
Cajal, Teresa Ramon y.;
Zhang, Junran;
Matias-Guiu, Xavier;
Dusso, Adriana;
Gonzalo, Susana

Publication type:

Article

EnABLing Cathepsin-Driven Melanoma Metastasis.

Published in:

Molecular & Cellular Oncology, 2018, v. 5, n. 4, p. 1, doi. 10.1080/23723556.2018.1458016

By:

Tripathi, Rakshamani;
Plattner, Rina

Publication type:

Article

Digestive proteolytic activity in Apodiphus amygdali Germar (Hemiptera: Pentatomidae): effect of endogenous inhibitors.

Published in:

Journal of Entomological & Acarological Research, 2014, v. 46, n. 2, p. 35, doi. 10.4081/jear.2014.1868

By:

Ramzi, S.;
Zibaee, A.

Publication type:

Article

Exploration of effect of Odanacatib on inhibiting orthodontic recurrence in rats and on CatK and IGF-1 mRNA.

Published in:

European Review for Medical & Pharmacological Sciences, 2019, v. 23, n. 8, p. 3151

By:

YE, J.;
ZHANG, P.-Y.;
GUAN, Z.-Q.;
WANG, G.-X.;
KOU, B.

Publication type:

Article

The application value of the detection of the level of tissue polypeptide antigen, ovarian cancer antigen X1, cathepsin L and CA125 on the diagnosis of epithelial ovarian cancer.

Published in:

European Review for Medical & Pharmacological Sciences, 2016, v. 20, n. 24, p. 5113

By:

LV, X-L;
ZHU, Y.;
LIU, J.-W.;
AI, H.

Publication type:

Article

Association between SNPs in the promoter region in cathepsin S and risk of asthma in Chinese Han population.

Published in:

European Review for Medical & Pharmacological Sciences, 2016, v. 20, n. 10, p. 2070

By:

ZHOU, P.-P.;
ZHANG, W.-Y.;
LI, Z.-F.;
CHEN, Y.-R.;
KANG, X.-C.;
JIANG, Y.-X.

Publication type:

Article

The effect of cathepsin K inhibitor surface treatment on delayed tooth replantation in dogs.

Published in:

2018

By:

Youngil Kwon;
Hyunjung Ko;
Soojung Kim;
Miri Kim;
Kwon, Youngil;
Ko, Hyunjung;
Kim, Soojung;
Kim, Miri

Publication type:

journal article

The effect of cathepsin K inhibitor on osteoclastic activity compared to alendronate and enamel matrix protein.

Published in:

Dental Traumatology, 2015, v. 31, n. 3, p. 202, doi. 10.1111/edt.12152

By:

Yang, Wonkyung;
Ko, Hyunjung;
Kim, Heesun;
Kim, Miri

Publication type:

Article

Cathepsins in oral diseases: mechanisms and therapeutic implications.

Published in:

Frontiers in Immunology, 2023, p. 01, doi. 10.3389/fimmu.2023.1203071

By:

Hao Jiang;
Zuoxiang Dong;
Xiaomin Xia;
Xue Li

Publication type:

Article

Spatial localization of cathepsins: Implications in immune activation and resolution during infections.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 01, doi. 10.3389/fimmu.2022.955407

By:

Anes, Elsa;
Pires, David;
Mandal, Manoj;
Azevedo-Pereira, José Miguel

Publication type:

Article

Mycobacterium bovis BCG Interferes with miR-3619-5p Control of Cathepsin S in the Process of Autophagy.

Published in:

Frontiers in Cellular & Infection Microbiology, 2016, v. 6, p. 1, doi. 10.3389/fcimb.2016.00027

By:

Pawar, Kamlesh;
Sharbati, Jutta;
Einspanier, Ralf;
Sharbati, Soroush

Publication type:

Article

Fluorescent image-guided surgery in breast cancer by intravenous application of a quenched fluorescence activity-based probe for cysteine cathepsins in a syngeneic mouse model.

Published in:

EJNMMI Research, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13550-020-00688-0

By:

Suurs, Frans V.;
Qiu, Si-Qi;
Yim, Joshua J.;
Schröder, Carolien P.;
Timmer-Bosscha, Hetty;
Bensen, Eric S.;
Santini, John T.;
de Vries, Elisabeth G. E.;
Bogyo, Matthew;
van Dam, Gooitzen M.

Publication type:

Article

The beneficial effects of L-cysteine on brain antioxidants of rats affected by sodium valproate.

Published in:

Human & Experimental Toxicology, 2017, v. 36, n. 11, p. 1212, doi. 10.1177/0960327117695634

By:

Hamza, R. Z.;
El-Shenawy, N. S.

Publication type:

Article

PAPILLON-LEFEVRE SYNDROME: A CASE REPORT.

Published in:

2012

By:

Kundu, Sanchita;
Zahir, Shabnam

Publication type:

Case Study

Cathepsin C Regulates Cytokine-Induced Apoptosis in β-Cell Model Systems.

Published in:

Genes, 2021, v. 12, n. 11, p. 1694, doi. 10.3390/genes12111694

By:

Fløyel, Tina;
Frørup, Caroline;
Størling, Joachim;
Pociot, Flemming

Publication type:

Article

Correction of a Splicing Mutation Affecting an Unverricht-Lundborg Disease Patient by Antisense Therapy.

Published in:

Genes, 2018, v. 9, n. 9, p. 455, doi. 10.3390/genes9090455

By:

Matos, Liliana;
Duarte, Ana Joana;
Ribeiro, Diogo;
Amaral, Olga;
Alves, Sandra;
Chaves, João

Publication type:

Article

P2X7 Receptor Function in Bone-Related Cancer.

Published in:

Journal of Osteoporosis, 2012, p. 1, doi. 10.1155/2012/637863

By:

Adinolfi, Elena;
Amoroso, Francesca;
Giuliani, Anna Lisa

Publication type:

Article

Abl and Arg mediate cysteine cathepsin secretion to facilitate melanoma invasion and metastasis.

Published in:

Science Signaling, 2018, v. 11, n. 518, p. 1, doi. 10.1126/scisignal.aao0422

By:

Tripathi, Rakshamani;
Fiore, Leann S.;
Richards, Dana L.;
Yang, Yuchen;
Liu, Jinpeng;
Wang, Chi;
Plattner, Rina

Publication type:

Article

Sargassum serratifolium attenuates RANKL-induced osteoclast differentiation and oxidative stress through inhibition of NF-κB and activation of the Nrf2/HO-1 signaling pathway.

Published in:

BioScience Trends, 2018, v. 12, n. 3, p. 257, doi. 10.5582/bst.2018.01107

By:

Hong Jae Kim;
Yung Hyun Choi;
Cheol Park;
Gi-Young Kim;
You-Jin Jeon;
Eui Kyun Park;
Suhkmann Kim;
Hye Jin Hwang

Publication type:

Article

A secreted schistosome cathepsin B1 cysteine protease and acute schistosome infection induce a transient T helper 17 response.

Published in:

PLoS Neglected Tropical Diseases, 2019, v. 13, n. 1, p. 1, doi. 10.1371/journal.pntd.0007070

By:

Soloviova, Kateryna;
Fox, Ellen C.;
Dalton, John P.;
Caffrey, Conor R.;
Davies, Stephen J.

Publication type:

Article

Update on drug development targeting parasite cysteine proteases.

Published in:

PLoS Neglected Tropical Diseases, 2018, p. 1, doi. 10.1371/journal.pntd.0005850

By:

McKerrow, James H.

Publication type:

Article

Cysteine proteases as digestive enzymes in parasitic helminths.

Published in:

PLoS Neglected Tropical Diseases, 2018, p. 1, doi. 10.1371/journal.pntd.0005840

By:

Caffrey, Conor R.;
Goupil, Louise;
Rebello, Karina M.;
Dalton, John P.;
Smith, David

Publication type:

Article

A novel nonsense mutation in cathepsin C gene in an Egyptian patient presenting with Papillon–Lefèvre syndrome.

Published in:

2015

By:

Soliman, Hala;
Gamal Eldeen, Heba;
Ibrahim Mustafa, Mustafa

Publication type:

Case Study

Critical COPD respiratory illness is linked to increased transcriptomic activity of neutrophil proteases genes.

Published in:

BMC Research Notes, 2012, v. 5, n. 1, p. 401, doi. 10.1186/1756-0500-5-401

By:

Almansa, Raquel;
Socias, Lorenzo;
Sanchez-Garcia, Monica;
Mart�n-Loeches, Ignacio;
del Olmo, Milagros;
Andaluz-Ojeda, David;
Bobillo, Felipe;
Rico, Lucia;
Herrero, Agueda;
Roig, Vicente;
San-Jose, C. Alicia;
Rosich, Sara;
Barbado, Julia;
Disdier, Carlos;
Ortiz de Lejarazu, Ra�l;
Gallegos, Maria C.;
Fernandez, Victoria;
Bermejo-Martin, Jesus F.

Publication type:

Article

Association between various cathepsins and uterine leiomyoma: A Mendelian randomization analysis.

Published in:

PLoS ONE, 2024, v. 19, n. 9, p. 1, doi. 10.1371/journal.pone.0310292

By:

Liu, Tingxiu;
Ren, Yuehan;
Zhang, Junning;
Yin, Hechun;
Zheng, Zheng;
Zhang, Mingyue;
Liao, Yan;
Yang, Liangliang;
Liu, Chang;
Liu, Xinmin;
Yan, Peiyu

Publication type:

Article

A selective genotyping approach identifies single nucleotide polymorphisms in porcine chromosome 2 genes associated with production and carcass traits in Italian heavy pigs.

Published in:

Italian Journal of Animal Science, 2011, v. 10, n. 2, p. 72, doi. 10.4081/ijas.2011.e15

By:

Fontanesi, Luca;
Scotti, Emilio;
Speroni, Camilla;
Buttazzoni, Luca;
Russo, Vincenzo

Publication type:

Article

Genetic diversity among Trypanosoma (Duttonella) vivax strains from Zambia and Ghana, based on cathepsin L-like gene.

Published in:

Parasite (1252607X), 2013, v. 20, p. 1, doi. 10.1051/parasite/2013024

By:

Nakayima, Jesca;
Ryo Nakao;
Alhassan, Andy;
Kyoko Hayashida;
Namangala, Boniface;
Kofi Afakye;
Chihiro Sugimoto

Publication type:

Article

Neutrophil proteinase 3 and dipeptidyl peptidase I (cathepsin C) as pharmacological targets in granulomatosis with polyangiitis (Wegener granulomatosis).

Published in:

Seminars in Immunopathology, 2013, v. 35, n. 4, p. 411, doi. 10.1007/s00281-013-0362-z

By:

Korkmaz, Brice;
Lesner, Adam;
Letast, Stephanie;
Mahdi, Yassir;
Jourdan, Marie-Lise;
Dallet-Choisy, Sandrine;
Marchand-Adam, Sylvain;
Kellenberger, Christine;
Viaud-Massuard, Marie-Claude;
Jenne, Dieter;
Gauthier, Francis

Publication type:

Article

A Broad Survey of Cathepsin K Immunoreactivity in Human Neoplasms.

Published in:

American Journal of Clinical Pathology, 2013, v. 139, n. 2, p. 151, doi. 10.1309/AJCPDTRTO2Z4UEXD

By:

Gang Zheng;
Martignoni, Guido;
Antonescu, Cristina;
Montgomery, Elizabeth;
Eberhart, Charles;
Netto, George;
Taube, Janis;
Westra, William;
Epstein, Jonathan I.;
Lotan, Tamara;
Maitra, Anirban;
Gabrielson, Edward;
Torbenson, Michael;
Iacobuzio-Donahue, Christine;
Demarzo, Angelo;
Ie Ming Shih;
Illei, Peter;
T. C. Wu;
Argani, Pedram

Publication type:

Article

Odanacatib increases mineralized callus during fracture healing in a rabbit ulnar osteotomy model.

Published in:

Journal of Orthopaedic Research, 2016, v. 34, n. 1, p. 72, doi. 10.1002/jor.22982

By:

Pennypacker, Brenda L.;
Gilberto, David;
Gatto, Nicholas T.;
Samadfam, Rana;
Smith, Susan Y.;
Kimmel, Donald B.;
Duong, Le Thi

Publication type:

Article