CASE REPORT Treatment of refractory hand warts by isolated limb infusion with melphalan and actinomycin D.

Damian, Diona L; Barnetson, Ross StC; Rose, Barbara R; Bonenkamp, Johannes J; Thompson, John F

SUMMARYWe present an immunocompetent man with extensive warts on the hands, refractory to a number of conventional treatment modalities and causing substantial morbidity and impairment of normal function. Isolated limb infusion (regional intra-arterial chemotherapy) with melphalan and actinomycin D was performed, with substantial clearing of the warts within 2 months. Treatment-induced morbidity was limited to mild local erythema and oedema which resolved within 3 weeks. After 9 months’ follow up, the patient had only a few residual warts and was able to resume normal activities.

WARTS treatment; ACTINOMYCIN; SKIN infections

Australasian Journal of Dermatology, 2001, Vol 42, Issue 2, p106

0004-8380

Academic Journal

10.1046/j.1440-0960.2001.00490.x