Works matching AU Korolchuk, Viktor I.
Results: 42
Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease models.
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- Cell Death & Disease, 2024, v. 15, n. 5, p. 1, doi. 10.1038/s41419-024-06770-y
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- Publication type:
- Article
Persistent mTORC1 signaling in cell senescence results from defects in amino acid and growth factor sensing.
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- Journal of Cell Biology, 2017, v. 216, n. 7, p. 1949, doi. 10.1083/jcb.201610113
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- Article
Lysosome-mediated processing of chromatin in senescence.
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- Journal of Cell Biology, 2013, v. 202, n. 1, p. 129, doi. 10.1083/jcb.201212110
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- Publication type:
- Article
Short senolytic or senostatic interventions rescue progression of radiation-induced frailty and premature ageing in mice.
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- eLife, 2022, p. 1, doi. 10.7554/eLife.75492
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- Publication type:
- Article
Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease.
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- Human Molecular Genetics, 2010, v. 19, n. 17, p. 3413, doi. 10.1093/hmg/ddq253
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- Article
Laforin, the most common protein mutated in Lafora disease, regulates autophagy.
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- Human Molecular Genetics, 2010, v. 19, n. 14, p. 2867, doi. 10.1093/hmg/ddq190
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- Article
PCV2 replication promoted by oxidative stress is dependent on the regulation of autophagy on apoptosis.
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- Veterinary Research, 2019, v. 50, n. 1, p. N.PAG, doi. 10.1186/s13567-019-0637-z
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- Article
The evolution of selective autophagy as a mechanism of oxidative stress response: The evolutionarily acquired ability of selective autophagy receptors to respond to oxidative stress is beneficial for human longevity.
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- BioEssays, 2023, v. 45, n. 11, p. 1, doi. 10.1002/bies.202300076
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- Article
Severe white matter astrocytopathy in CADASIL.
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- Brain Pathology, 2018, v. 28, n. 6, p. 832, doi. 10.1111/bpa.12621
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- Article
Oxidation of SQSTM1/p62 mediates the link between redox state and protein homeostasis.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-017-02746-z
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- Article
Nutrient sensing, growth and senescence.
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- FEBS Journal, 2018, v. 285, n. 11, p. 1948, doi. 10.1111/febs.14400
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- Article
Dynamic Modelling of Pathways to Cellular Senescence Reveals Strategies for Targeted Interventions.
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- PLoS Computational Biology, 2014, v. 10, n. 8, p. 1, doi. 10.1371/journal.pcbi.1003728
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- Publication type:
- Article
Genomic targets and selective inhibition of DNA methyltransferase isoforms.
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- Clinical Epigenetics, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13148-022-01325-4
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- Publication type:
- Article
Mechanisms of cross-talk between the ubiquitin-proteasome and autophagy-lysosome systems
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- FEBS Letters, 2010, v. 584, n. 7, p. 1393, doi. 10.1016/j.febslet.2009.12.047
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- Article
Mitochondrial sodium/calcium exchanger (NCLX) regulates basal and starvation‐induced autophagy through calcium signaling.
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- FASEB Journal, 2024, v. 38, n. 3, p. 1, doi. 10.1096/fj.202301368RR
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- Article
Redox signalling in physiology, ageing and disease.
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- 2020
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- Publication type:
- Editorial
The crosstalk of NAD, ROS and autophagy in cellular health and ageing.
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- Biogerontology, 2020, v. 21, n. 3, p. 381, doi. 10.1007/s10522-020-09864-0
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- Article
The mTORC1-autophagy pathway is a target for senescent cell elimination.
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- Biogerontology, 2019, v. 20, n. 3, p. 331, doi. 10.1007/s10522-019-09802-9
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- Article
Lipids, lysosomes and mitochondria: insights into Lewy body formation from rare monogenic disorders.
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- Acta Neuropathologica, 2021, v. 141, n. 4, p. 511, doi. 10.1007/s00401-021-02266-7
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- Publication type:
- Article
Rapamycin improves healthspan but not inflammaging in nfκb1<sup>−/−</sup> mice.
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- Aging Cell, 2019, v. 18, n. 1, p. N.PAG, doi. 10.1111/acel.12882
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- Publication type:
- Article
Eps 15 and Dap 160 control synaptic vesicle membrane retrieval and synapse development.
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- Journal of Cell Biology, 2007, v. 178, n. 2, p. 309, doi. 10.1083/jcb.200701030
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- Publication type:
- Article
PEG-lipid micelles enable cholesterol efflux in Niemann-Pick Type C1 disease-based lysosomal storage disorder.
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- Scientific Reports, 2016, p. 31750, doi. 10.1038/srep31750
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- Article
Connexin43 promotes exocytosis of damaged lysosomes through actin remodelling.
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- EMBO Journal, 2024, v. 43, n. 17, p. 3627, doi. 10.1038/s44318-024-00177-3
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- Publication type:
- Article
NDP52 acts as a redox sensor in PINK1/Parkin‐mediated mitophagy.
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- EMBO Journal, 2023, v. 42, n. 5, p. 1, doi. 10.15252/embj.2022111372
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- Publication type:
- Article
Oxidative stress‐induced phosphorylation of JIP4 regulates lysosomal positioning in coordination with TRPML1 and ALG2.
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- EMBO Journal, 2022, v. 41, n. 22, p. 1, doi. 10.15252/embj.2022111476
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- Publication type:
- Article
mTORC1 and Nutrient Homeostasis: The Central Role of the Lysosome.
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- International Journal of Molecular Sciences, 2018, v. 19, n. 3, p. 818, doi. 10.3390/ijms19030818
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- Publication type:
- Article
CK2 and GAK/auxilin2 Are Major Protein Kinases in Clathrin-Coated Vesicles.
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- Traffic, 2002, v. 3, n. 6, p. 428, doi. 10.1034/j.1600-0854.2002.30606.x
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- Article
Lysosomal positioning coordinates cellular nutrient responses.
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- Nature Cell Biology, 2011, v. 13, n. 4, p. 453, doi. 10.1038/ncb2204
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- Publication type:
- Article
Transcriptional block of AMPK-induced autophagy promotes glutamate excitotoxicity in nutrient-deprived SH-SY5Y neuroblastoma cells.
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- Cellular & Molecular Life Sciences, 2020, v. 77, n. 17, p. 3383, doi. 10.1007/s00018-019-03356-2
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- Publication type:
- Article
mTORC1 as the main gateway to autophagy.
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- Essays in Biochemistry, 2017, v. 61, n. 6, p. 565, doi. 10.1042/EBC20170027
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- Publication type:
- Article
Signalling mechanisms in autophagy: an introduction to the issue.
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- Essays in Biochemistry, 2017, v. 61, n. 6, p. 561, doi. 10.1042/EBC20170116
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- Publication type:
- Article
Autophagy and ageing: implications for age-related neurodegenerative diseases.
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- Essays in Biochemistry, 2013, v. 55, p. 119, doi. 10.1042/BSE0550119
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- Publication type:
- Article
Oncogenic PIK3CA corrupts growth factor signaling specificity.
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- Molecular Systems Biology, 2025, v. 21, n. 2, p. 126, doi. 10.1038/s44320-024-00078-x
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- Article
Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity.
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- eLife, 2016, p. 1, doi. 10.7554/eLife.11058
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- Publication type:
- Article
Complement modulation reverses pathology in Y402H‐retinal pigment epithelium cell model of age‐related macular degeneration by restoring lysosomal function.
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- Stem Cells Translational Medicine, 2020, v. 9, n. 12, p. 1585, doi. 10.1002/sctm.20-0211
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- Publication type:
- Article
Variation in the Structure of Bird Nests between Northern Manitoba and Southeastern Ontario.
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- PLoS ONE, 2011, v. 6, n. 4, p. 1, doi. 10.1371/journal.pone.0019087
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- Publication type:
- Article
Mitophagy as a guardian against cellular aging.
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- Autophagy, 2025, v. 21, n. 1, p. 249, doi. 10.1080/15548627.2024.2414461
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- Publication type:
- Article
Metabolic function of autophagy is essential for cell survival.
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- Autophagy, 2023, v. 19, n. 8, p. 2395, doi. 10.1080/15548627.2023.2165753
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- Publication type:
- Article
SQSTM1/p62 mediates crosstalk between autophagy and the UPS in DNA repair.
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- Autophagy, 2016, v. 12, n. 10, p. 1917, doi. 10.1080/15548627.2016.1210368
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- Publication type:
- Article
Restarting stalled autophagy a potential therapeutic approach for the lipid storage disorder, Niemann-Pick type C1 disease.
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- Autophagy, 2014, v. 10, n. 6, p. 1137, doi. 10.4161/auto.28623
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- Publication type:
- Article
Regulation of autophagy by lysosomal positioning.
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- Autophagy, 2011, v. 7, n. 8, p. 927, doi. 10.4161/auto.7.8.15862
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- Publication type:
- Article
Impaired autophagy in Lafora disease.
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- Autophagy, 2010, v. 6, n. 7, p. 991, doi. 10.4161/auto.6.7.13308
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- Publication type:
- Article