Works matching AU Scammells, Peter
Results: 43
Solution NMR characterization of apical membrane antigen 1 and small molecule interactions as a basis for designing new antimalarials.
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- Journal of Molecular Recognition, 2016, v. 29, n. 6, p. 281, doi. 10.1002/jmr.2529
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- Article
Design, Synthesis, and Biological Evaluation of Tetra-Substituted Thiophenes as Inhibitors of p38α MAPK.
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- ChemistryOpen, 2015, v. 4, n. 1, p. 56, doi. 10.1002/open.201402076
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- Article
Total Synthesis of (−)-Episilvestrol and (−)-Silvestrol.
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- Angewandte Chemie International Edition, 2007, v. 46, n. 41, p. 7835, doi. 10.1002/anie.200702700
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- Article
NMR case study of ropinirole: concentration-dependent effects of nonexchangeable proton resonances.
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- 2014
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- Publication type:
- Other
Genetic and chemical validation of Plasmodium falciparum aminopeptidase PfA-M17 as a drug target in the hemoglobin digestion pathway.
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- eLife, 2022, p. 1, doi. 10.7554/eLife.80813
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- Article
Nitrogen-Containing Ionic Liquids: Biodegradation Studies and Utility in Base-Mediated Reactions.
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- Australian Journal of Chemistry, 2015, v. 68, n. 6, p. 849, doi. 10.1071/CH14499
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- Publication type:
- Article
Effect of a novel partial adenosine A<sub>1</sub> receptor agonist VCP102 in reducing ischemic damage in the mouse heart.
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- Drug Development Research, 2007, v. 68, n. 8, p. 529, doi. 10.1002/ddr.20220
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- Article
Structure and substrate fingerprint of aminopeptidase P from Plasmodium falciparum.
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- Biochemical Journal, 2016, v. 473, n. 19, p. 3189, doi. 10.1042/BCJ20160550
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- Article
The role of kinetic context in apparent biased agonism at GPCRs.
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- Nature Communications, 2016, v. 7, n. 2, p. 10842, doi. 10.1038/ncomms10842
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- Publication type:
- Article
Screening the Medicines for Malaria Venture "Malaria Box" against the Plasmodium falciparum Aminopeptidases, M1, M17 and M18.
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- PLoS ONE, 2015, v. 10, n. 2, p. 1, doi. 10.1371/journal.pone.0115859
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- Publication type:
- Article
Zwitterionic Modification of Ultrasmall Iron Oxide Nanoparticles for Reduced Protein Corona Formation.
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- ChemPlusChem, 2017, v. 82, n. 4, p. 638, doi. 10.1002/cplu.201700052
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- Publication type:
- Article
Chemoproteomics validates selective targeting of Plasmodium M1 alanyl aminopeptidase as an antimalarial strategy.
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- eLife, 2024, p. 1, doi. 10.7554/eLife.92990
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- Publication type:
- Article
1,3‐Benzodioxole‐Modified Noscapine Analogues: Synthesis, Antiproliferative Activity, and Tubulin‐Bound Structure.
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- ChemMedChem, 2021, v. 16, n. 18, p. 2882, doi. 10.1002/cmdc.202100363
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- Publication type:
- Article
Development of Novel 4‐Arylpyridin‐2‐one and 6‐Arylpyrimidin‐4‐one Positive Allosteric Modulators of the M<sub>1</sub> Muscarinic Acetylcholine Receptor.
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- ChemMedChem, 2021, v. 16, n. 1, p. 216, doi. 10.1002/cmdc.202000540
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- Publication type:
- Article
A Structure−Activity Relationship Study of Novel Hydroxamic Acid Inhibitors around the S1 Subsite of Human Aminopeptidase N.
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- ChemMedChem, 2021, v. 16, n. 1, p. 234, doi. 10.1002/cmdc.202000527
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- Publication type:
- Article
Front Cover: A Novel Class of N‐Sulfonyl and N‐Sulfamoyl Noscapine Derivatives that Promote Mitotic Arrest in Cancer Cells (ChemMedChem 23/2019).
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- ChemMedChem, 2019, v. 14, n. 23, p. 1950, doi. 10.1002/cmdc.201900651
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- Publication type:
- Article
A Novel Class of N‐Sulfonyl and N‐Sulfamoyl Noscapine Derivatives that Promote Mitotic Arrest in Cancer Cells.
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- ChemMedChem, 2019, v. 14, n. 23, p. 1968, doi. 10.1002/cmdc.201900477
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- Publication type:
- Article
Identification of the Binding Site of Apical Membrane Antigen 1 (AMA1) Inhibitors Using a Paramagnetic Probe.
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- ChemMedChem, 2019, v. 14, n. 5, p. 603, doi. 10.1002/cmdc.201800802
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- Publication type:
- Article
Guidelines for the Synthesis of Small-Molecule Irreversible Probes Targeting G Protein-Coupled Receptors.
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- ChemMedChem, 2016, v. 11, n. 14, p. 1488, doi. 10.1002/cmdc.201600066
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- Publication type:
- Article
The Synthesis and Biological Evaluation of Multifunctionalised Derivatives of Noscapine as Cytotoxic Agents.
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- ChemMedChem, 2014, v. 9, n. 2, p. 399, doi. 10.1002/cmdc.201300395
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- Publication type:
- Article
Effect of Linker Length and Composition on Heterobivalent Ligand-Mediated Receptor Cross-Talk between the A<sub>1</sub> Adenosine and β<sub>2</sub> Adrenergic Receptors.
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- ChemMedChem, 2013, v. 8, n. 12, p. 2036, doi. 10.1002/cmdc.201300286
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- Publication type:
- Article
Synthesis and Biological Evaluation of N-Substituted Noscapine Analogues.
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- ChemMedChem, 2012, v. 7, n. 12, p. 2122, doi. 10.1002/cmdc.201200365
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- Publication type:
- Article
Synthesis and Biological Evaluation of Adenosines with Heterobicyclic and Polycyclic N<sup>6</sup>-Substituents as Adenosine A<sub>1</sub> Receptor Agonists.
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- ChemMedChem, 2012, v. 7, n. 7, p. 1191, doi. 10.1002/cmdc.201200208
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- Publication type:
- Article
Design Strategies for Bivalent Ligands Targeting GPCRs.
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- ChemMedChem, 2011, v. 6, n. 6, p. 963, doi. 10.1002/cmdc.201100101
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- Publication type:
- Article
Synthesis of Thieno-Fused Heterocycles through Reiterative Iodocyclization.
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- Advanced Synthesis & Catalysis, 2014, v. 356, n. 9, p. 1974, doi. 10.1002/adsc.201400072
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- Publication type:
- Article
Enantioenriched Positive Allosteric Modulators Display Distinct Pharmacology at the Dopamine D 1 Receptor.
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- Molecules, 2021, v. 26, n. 13, p. 3799, doi. 10.3390/molecules26133799
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- Publication type:
- Article
Ionic Liquid Forms of the Antimalarial Lumefantrine in Combination with LFCS Type IIIB Lipid-Based Formulations Preferentially Increase Lipid Solubility, In Vitro Solubilization Behavior and In Vivo Exposure.
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- Pharmaceutics, 2020, v. 12, n. 1, p. 17, doi. 10.3390/pharmaceutics12010017
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- Publication type:
- Article
An Allosteric Modulator of the Adenosine A<sub>1</sub> Receptor Improves Cardiac Function Following Ischaemia in Murine Isolated Hearts.
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- Pharmaceuticals (14248247), 2013, v. 6, n. 4, p. 546, doi. 10.3390/ph6040546
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- Publication type:
- Article
VCP746, a novel A<sub>1</sub> adenosine receptor biased agonist, reduces hypertrophy in a rat neonatal cardiac myocyte model.
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- Clinical & Experimental Pharmacology & Physiology, 2016, v. 43, n. 10, p. 976, doi. 10.1111/1440-1681.12616
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- Publication type:
- Article
The effect of two selective A<sub>1</sub> -receptor agonists and the bitopic ligand VCP746 on heart rate and regional vascular conductance in conscious rats.
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- 2020
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- Publication type:
- journal article
Probe dependence of allosteric enhancers on the binding affinity of adenosine A<sub>1</sub> -receptor agonists at rat and human A<sub>1</sub> -receptors measured using NanoBRET.
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- 2019
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- Publication type:
- journal article
Cryptic pocket formation underlies allosteric modulator selectivity at muscarinic GPCRs.
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- Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11062-7
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- Publication type:
- Article
Development of Inhibitors of Plasmodium falciparum Apical Membrane Antigen 1 Based on Fragment Screening.
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- Australian Journal of Chemistry, 2013, v. 66, n. 12, p. 1530, doi. 10.1071/CH13266
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- Publication type:
- Article
A Multi-Step Continuous Flow Process for the N-Demethylation of Alkaloids.
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- Australian Journal of Chemistry, 2013, v. 66, n. 2, p. 17, doi. 10.1071/CH12463
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- Publication type:
- Article
Efficient Iron-Catalyzed N-Demethylation of Tertiary Amine-N-oxides under Oxidative Conditions.
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- Australian Journal of Chemistry, 2011, v. 64, n. 11, p. 21, doi. 10.1071/CH11320
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- Publication type:
- Article
Driving antimalarial design through understanding of target mechanism.
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- Biochemical Society Transactions, 2020, v. 48, n. 5, p. 2067, doi. 10.1042/BST20200224
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- Publication type:
- Article
Virtual screening using a conformationally flexible target protein: models for ligand binding to p38α MAPK.
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- Journal of Computer-Aided Molecular Design, 2012, v. 26, n. 4, p. 409, doi. 10.1007/s10822-012-9569-7
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- Publication type:
- Article
Biased Agonism at G Protein-Coupled Receptors: The Promise and the Challenges-A Medicinal Chemistry Perspective.
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- Medicinal Research Reviews, 2014, v. 34, n. 6, p. 1286, doi. 10.1002/med.21318
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- Publication type:
- Article
Biocompatible Cationic Lipoamino Acids as Counterions for Oral Administration of API-Ionic Liquids.
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- Pharmaceutical Research, 2022, v. 39, n. 10, p. 2405, doi. 10.1007/s11095-022-03305-y
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- Publication type:
- Article
Lipophilic Salts and Lipid-Based Formulations: Enhancing the Oral Delivery of Octreotide.
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- Pharmaceutical Research, 2021, v. 38, n. 6, p. 1125, doi. 10.1007/s11095-021-03063-3
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- Publication type:
- Article
Synthesis and Utility of 2-Halo- O.
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- European Journal of Organic Chemistry, 2011, v. 2011, n. 6, p. 1092, doi. 10.1002/ejoc.201001395
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- Publication type:
- Article
Grignard Reactions in Pyridinium and Phosphonium Ionic Liquids.
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- European Journal of Organic Chemistry, 2011, v. 2011, n. 5, p. 942, doi. 10.1002/ejoc.201001468
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- Publication type:
- Article
A new mechanism of allostery in a G protein-coupled receptor dimer.
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- Nature Chemical Biology, 2014, v. 10, n. 9, p. 745, doi. 10.1038/nchembio.1593
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- Publication type:
- Article