Works matching DE "THERAPEUTIC use of RNA interference"

Results: 80

The emerging role of epigenetics in pulmonary arterial hypertension: an important avenue for clinical trials (2015 Grover Conference Series).

Published in:

Pulmonary Circulation, 2016, v. 6, n. 3, p. 274, doi. 10.1086/687765

By:

Huston, Jessica H.;
Ryan, John J.

Publication type:

Article

The antisense 5' end of the V2 gene confers enhanced resistance against the monopartite begomovirus cotton leaf curl Kokhran virus-Burewala strain.

Published in:

Acta Virologica, 2019, v. 63, n. 1, p. 26, doi. 10.4149/av_2019_101

By:

ALI, I.;
KHURSHID, M.;
IQBAL, Z.;
SHAFIQ, M.;
AMIN, I.;
MANSOOR, S.;
BRIDDON, R. W.

Publication type:

Article

Vertically integrated translational studies of PDX1 as a therapeutic target for pancreatic cancer via a novel bifunctional RNAi platform.

Published in:

Cancer Gene Therapy, 2014, v. 21, n. 2, p. 48, doi. 10.1038/cgt.2013.84

By:

Wu, J;
Liu, S;
Yu, J;
Zhou, G;
Rao, D;
Jay, C M;
Kumar, P;
Sanchez, R;
Templeton, N;
Senzer, N;
Maples, P;
Nemunaitis, J;
Brunicardi, F C

Publication type:

Article

ZFX regulates glioma cell proliferation and survival in vitro and in vivo.

Published in:

Journal of Neuro-Oncology, 2013, v. 112, n. 1, p. 17, doi. 10.1007/s11060-012-1032-z

By:

Zhu, Zhichuan;
Li, Kui;
Xu, Dafeng;
Liu, Yongjie;
Tang, Hailiang;
Xie, Qing;
Xie, Liqian;
Liu, Jiwei;
Wang, Hongtao;
Gong, Ye;
Hu, Zelan;
Zheng, Jing

Publication type:

Article

Knockdown of RLIP76 expression by RNA interference inhibits invasion, induces cell cycle arrest, and increases chemosensitivity to the anticancer drug temozolomide in glioma cells.

Published in:

Journal of Neuro-Oncology, 2013, v. 112, n. 1, p. 73, doi. 10.1007/s11060-013-1045-2

By:

Wang, Qi;
Qian, Jun;
Wang, JunYu;
Luo, Chun;
Chen, Juxiang;
Hu, Guohan;
Lu, Yicheng

Publication type:

Article

RNA–Protein Interactions Prevent Long RNA Duplex Formation: Implications for the Design of RNA-Based Therapeutics.

Published in:

Molecules, 2018, v. 23, n. 12, p. 3329, doi. 10.3390/molecules23123329

By:

Bindewald, Eckart;
Dai, Lisheng;
Kasprzak, Wojciech K.;
Kim, Taejin;
Gu, Shuo;
Shapiro, Bruce A.

Publication type:

Article

Construction and Biological Evaluation of a Novel Integrin ανβ3-Specific Carrier for Targeted siRNA Delivery In Vitro.

Published in:

Molecules, 2017, v. 22, n. 2, p. 231, doi. 10.3390/molecules22020231

By:

Xueqi Chen;
Meng Liu;
Rongfu Wang;
Ping Yan;
Chunli Zhang;
Chao Ma;
Lei Yin

Publication type:

Article

Understanding the antiviral effects of RNAi-based therapy in HBeAg-positive chronic hepatitis B infection.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-020-80594-6

By:

Kadelka, Sarah;
Dahari, Harel;
Ciupe, Stanca M.

Publication type:

Article

Silencing human genetic diseases with oligonucleotide-based therapies.

Published in:

Human Genetics, 2013, v. 132, n. 5, p. 481, doi. 10.1007/s00439-013-1288-1

By:

Martínez, Tamara;
Wright, Natalia;
López-Fraga, Marta;
Jiménez, Ana;
Pañeda, Covadonga

Publication type:

Article

Inhibition of Tumor Growth via Systemic siRNA Delivery Using Reducible Bile Acid-Conjugated Polyethylenimine.

Published in:

Polymers (20734360), 2018, v. 10, n. 9, p. 953, doi. 10.3390/polym10090953

By:

Yin, Yue;
Lee, Jung Eun;
Kim, Nak Won;
Lee, Jong Han;
Lim, Su Yeon;
Kim, E Seul;
Park, Ji Won;
Lee, Min Sang;
Jeong, Ji Hoon

Publication type:

Article

Update on the clinical utility of an RNA interference-based treatment: focus on Patisiran.

Published in:

Pharmacogenomics & Personalized Medicine, 2017, v. 10, p. 267, doi. 10.2147/PGPM.S87945

By:

Rizk, Malak;
Tüzmen, Şükrü

Publication type:

Article

Significance and applications of nanoparticles in siRNA delivery for cancer therapy.

Published in:

Expert Review of Clinical Pharmacology, 2012, v. 5, n. 4, p. 403, doi. 10.1586/ECP.12.33

By:

Muhammad Ali, Hafiz;
Urbinati, Giorgia;
Massaad-Massade, Mouna Raouane Liliane

Publication type:

Article

Antiviral Stratagems Against HIV-1 Using RNA Interference (RNAi) Technology.

Published in:

Evolutionary Bioinformatics, 2013, n. 9, p. 203, doi. 10.4137/EBO.S11412

By:

Vlachakis, Dimitrios;
Tsiliki, Georgia;
Pavlopoulou, Athanasia;
Roubelakis, Maria G.;
Champeris Tsaniras, Spyridon;
Kossida, Sophia

Publication type:

Article

Biodegradable Inorganic Nanovector: Passive versus Active Tumor Targeting in siRNA Transportation.

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 14, p. 4582, doi. 10.1002/anie.201510844

By:

Park, Dae-Hwan;
Cho, Jaeyong;
Kwon, Oh-Joon;
Yun, Chae-Ok;
Choy, Jin-Ho

Publication type:

Article

A Multi-RNAi Microsponge Platform for Simultaneous Controlled Delivery of Multiple Small Interfering RNAs.

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 10, p. 3347, doi. 10.1002/anie.201508978

By:

Roh, Young Hoon;
Deng, Jason Z.;
Dreaden, Erik C.;
Park, Jae Hyon;
Yun, Dong Soo;
Shopsowitz, Kevin E.;
Hammond, Paula T.

Publication type:

Article

At the hypusine of the crime.

Published in:

2012

By:

Burgess, Darren J.

Publication type:

journal article

Down-regulation of G protein-coupled receptor 137 by RNA interference inhibits cell growth of two hepatoma cell lines.

Published in:

Cell Biology International, 2015, v. 39, n. 4, p. 418, doi. 10.1002/cbin.10412

By:

Shao, Xin;
Liu, Yong;
Huang, Hai;
Zhuang, Linyuan;
Luo, Tianping;
Huang, Huping;
Ge, Xinguo

Publication type:

Article

Silencing of AP-4 inhibits proliferation, induces cell cycle arrest and promotes apoptosis in human lung cancer cells.

Published in:

Oncology Letters, 2016, v. 11, n. 6, p. 3735, doi. 10.3892/ol.2016.4451

By:

XUANYU HU;
WEI GUO;
SHANSHAN CHEN;
YIZHUO XU;
PING LI;
HUAQI WANG;
HEYING CHU;
JUAN LI;
YUWEN DU;
XIAONAN CHEN;
GUOJUN ZHANG;
GUOQIANG ZHAO

Publication type:

Article

Combined RNAi targeting human Stat3 and ADAM9 as gene therapy for non-small cell lung cancer.

Published in:

Oncology Letters, 2016, v. 11, n. 2, p. 1242, doi. 10.3892/ol.2015.4018

By:

LIANG CHANG;
FANGCHAO GONG;
HONGFEI CAI;
ZHIHONG LI;
YOUBIN CUI

Publication type:

Article

Oncolytic adenovirus-expressed RNA interference of O6-methylguanine DNA methyltransferase activity may enhance the antitumor effects of temozolomide.

Published in:

Oncology Letters, 2014, v. 8, n. 5, p. 2201, doi. 10.3892/ol.2014.2442

By:

XIN-JUN CHEN;
KAI ZHANG;
YONG XIN;
GUAN JIANG

Publication type:

Article

Tolerogenic dendritic cells produced by lentiviral-mediated CD40- and interleukin-23p19-specific shRNA can ameliorate experimental autoimmune encephalomyelitis by suppressing T helper type 17 cells.

Published in:

Clinical & Experimental Immunology, 2014, v. 176, n. 2, p. 180, doi. 10.1111/cei.12266

By:

Kalantari, T.;
Karimi, M. H.;
Ciric, B.;
Yan, Y.;
Rostami, A.;
Kamali‐Sarvestani, E.

Publication type:

Article

DNA/ RNA heteroduplex oligonucleotide for highly efficient gene silencing.

Published in:

Clinical & Experimental Neuroimmunology, 2016, v. 7, n. 2, p. 108, doi. 10.1111/cen3.12303

By:

Yokota, Takanori

Publication type:

Article

R049: Airway Injury Model for the Application of RNAi Therapy.

Published in:

2006

By:

Senchak, Andrew J.;
Bothwell, Nici Eddy;
Shvidler, Joseph;
Cable, Benjamin B

Publication type:

Abstract

Big pharma shows signs of renewed interest in RNAi drugs.

Published in:

Nature Medicine, 2014, v. 20, n. 2, p. 109, doi. 10.1038/nm0214-109

By:

Zeliadt, Nicholette

Publication type:

Article

Advances, Nuances, and Potential Pitfalls When Exploiting the Therapeutic Potential of RNA Interference.

Published in:

Clinical Pharmacology & Therapeutics, 2015, v. 97, n. 1, p. 79, doi. 10.1002/cpt.8

By:

Battistella, M;
Marsden, PA

Publication type:

Article

RNA Interference: Molecular mechanism and milestone therapeutic applications.

Published in:

Journal of Cell & Molecular Biology, 2014, v. 12, n. 1/2, p. 11

By:

IRFAN, Muhammad;
MEHMOOD, Sajid

Publication type:

Article

Engineering Multifunctional RNAi Nanomedicine To Concurrently Target Cancer Hallmarks for Combinatorial Therapy.

Published in:

Angewandte Chemie, 2018, v. 130, n. 6, p. 1526, doi. 10.1002/ange.201710144

By:

Liu, Yanlan;
Ji, Xiaoyuan;
Tong, Winnie W. L.;
Askhatova, Diana;
Yang, Tingyuan;
Cheng, Hongwei;
Wang, Yuzhuo;
Shi, Jinjun

Publication type:

Article

Technology: Investment suggests RNAi is on the up.

Published in:

Nature, 2014, v. 510, n. 7503, p. 35, doi. 10.1038/510035b

By:

Maraganore, John

Publication type:

Article

RNA interference rebooted.

Published in:

Nature, 2014, v. 508, n. 7497, p. 443, doi. 10.1038/508443a

By:

Check Hayden, Erika

Publication type:

Article

Nanotechnology: RNAi-based nanoparticles zap glioblastoma.

Published in:

Nature Reviews Drug Discovery, 2014, v. 13, n. 1, p. 20, doi. 10.1038/nrd4214

By:

Harrison, Charlotte

Publication type:

Article

Trial watch: Pioneering RNAi therapy shows antitumour activity in humans.

Published in:

Nature Reviews Drug Discovery, 2013, v. 12, n. 3, p. 178, doi. 10.1038/nrd3962

By:

Crunkhorn, Sarah

Publication type:

Article

miR-101-2, miR-125b-2 and miR-451a act as potential tumor suppressors in gastric cancer through regulation of the PI3K/AKT/mTOR pathway.

Published in:

Cellular Oncology (2211-3428), 2016, v. 39, n. 1, p. 23, doi. 10.1007/s13402-015-0247-3

By:

Riquelme, Ismael;
Tapia, Oscar;
Sandoval, Alejandra;
Buchegger, Kurt;
Leal, Pamela;
Varga, Matthew;
Peek, Richard;
Letelier, Pablo;
Bizama, Carolina;
Espinoza, Jaime;
Roa, Juan;
Araya, Juan

Publication type:

Article

The small non-coding RNA response to virus infection in the Leishmania vector Lutzomyia longipalpis.

Published in:

PLoS Neglected Tropical Diseases, 2018, v. 12, n. 6, p. 1, doi. 10.1371/journal.pntd.0006569

By:

Ferreira, Flávia Viana;
Aguiar, Eric Roberto Guimarães Rocha;
Olmo, Roenick Proveti;
de Oliveira, Karla Pollyanna Vieira;
Silva, Emanuele Guimarães;
Sant'Anna, Maurício Roberto Viana;
Gontijo, Nelder de Figueiredo;
Kroon, Erna Geessien;
Imler, Jean Luc;
Marques, João Trindade

Publication type:

Article

Medical applications of RNA interference (RNAi).

Published in:

BMC Proceedings, 2013, v. 7, n. Suppl 2, p. 1, doi. 10.1186/1753-6561-7-S2-K21

By:

Pereira, Tiago Campos;
Lopes-Cendes, Iscia

Publication type:

Article

Evaluation and control of miRNA-like off-target repression for RNA interference.

Published in:

Cellular & Molecular Life Sciences, 2018, v. 75, n. 5, p. 797, doi. 10.1007/s00018-017-2656-0

By:

Seok, Heeyoung;
Lee, Haejeong;
Jang, Eun-Sook;
Chi, Sung Wook

Publication type:

Article

Overview of RNA interference therapeutics.

Published in:

Songklanakarin Journal of Science & Technology, 2012, v. 34, n. 3, p. 293

By:

Panjaworayan, Nattanan T-Thienprasert

Publication type:

Article

RNA interference targeting carbohydrate sulfotransferase 3 diminishes macrophage accumulation, inhibits MMP-9 expression and promotes lung recovery in murine pulmonary emphysema.

Published in:

2015

By:

Yoshiro Kai;
Koichi Tomoda;
Hiroyuki Yoneyama;
Masanori Yoshikawa;
Hiroshi Kimura;
Kai, Yoshiro;
Tomoda, Koichi;
Yoneyama, Hiroyuki;
Yoshikawa, Masanori;
Kimura, Hiroshi

Publication type:

journal article

Gemellus.

Published in:: Colorectal Disease, 2012, v. 14, n. 12, p. 1560, doi. 10.1111/codi.12060
Publication type:: Article

EpCAM-targeted liposomal si-RNA delivery for treatment of epithelial cancer.

Published in:

Drug Delivery, 2016, v. 23, n. 4, p. 1101, doi. 10.3109/10717544.2014.973082

By:

Bhavsar, Dhiraj;
Subramanian, Krishnakumar;
Sethuraman, Swaminathan;
Krishnan, Uma Maheswari

Publication type:

Article

Enzyme kinetics and distinct modulation of the protein kinase N family of kinases by lipid activators and small molecule inhibitors.

Published in:

Bioscience Reports, 2014, v. 34, n. 2, p. 93, doi. 10.1042/BSR20140010

By:

FALK, Matthew D.;
Wei LIU;
BOLAÑOS, Ben;
UNSAL-KACMAZ, Keziban;
KLIPPEL, Anke;
GRANT, Stephan;
BROOUN, Alexei;
TIMOFEEVSKI, Sergei

Publication type:

Article

Correction to: The Race of 10 Synthetic RNAi-Based Drugs to the Pharmaceutical Market.

Published in:

2018

By:

Titze-de-Almeida, Ricardo;
David, Catherine;
Titze-de-Almeida, Simoneide Souza

Publication type:

Correction Notice

Hemocompatibility Assessment of two siRNA Nanocarrier Formulations.

Published in:

Pharmaceutical Research, 2014, v. 31, n. 11, p. 3127, doi. 10.1007/s11095-014-1405-4

By:

Yousefi, Afrouz;
Lauwers, Marianne;
Nemes, Reka;
Holten, Thijs;
Babae, Negar;
Roest, Mark;
Storm, Gert;
Schiffelers, Raymond;
Mastrobattista, Enrico

Publication type:

Article

Markets, venture investors and big pharma interest in RNAi soars.

Published in:

Nature Biotechnology, 2014, v. 32, n. 3, p. 203, doi. 10.1038/nbt0314-203

By:

Bouchie, Aaron

Publication type:

Article

Image-based analysis of lipid nanoparticle-mediated siRNA delivery, intracellular trafficking and endosomal escape.

Published in:

Nature Biotechnology, 2013, v. 31, n. 7, p. 638, doi. 10.1038/nbt.2612

By:

Gilleron, Jerome;
Querbes, William;
Zeigerer, Anja;
Borodovsky, Anna;
Marsico, Giovanni;
Schubert, Undine;
Manygoats, Kevin;
Seifert, Sarah;
Andree, Cordula;
Stöter, Martin;
Epstein-Barash, Hila;
Zhang, Ligang;
Koteliansky, Victor;
Fitzgerald, Kevin;
Fava, Eugenio;
Bickle, Marc;
Kalaidzidis, Yannis;
Akinc, Akin;
Maier, Martin;
Zerial, Marino

Publication type:

Article

SYNTHESIS AND CHARACTERIZATION OF GRP78 SIRNAS FOR SILENCING GENE EXPRESSION IN HEPG2 LIVER CARCINOMA CELLS.

Published in:

Bulletin: New Jersey Academy of Science, 2014, v. 59, n. 1, p. 1

By:

MAINA, ANTHONY;
MOROZKO, EVA;
BENDER, MARIA E.;
BLACKMAN, BRITTANY;
PARRONCHI, CHRIS;
BLAKE, ALLAN D.;
SABATINO, DAVID

Publication type:

Article

Study of RNA Interference Targeting NET-1 Combination with Sorafenib for Hepatocellular Carcinoma Therapy In Vitro and In Vivo.

Published in:

Gastroenterology Research & Practice, 2013, p. 1, doi. 10.1155/2013/685150

By:

Song He;
Ying-ze Wei;
Gui-lan Wang;
Yu-yin Xu;
Jia-ming Zhou;
Yi-xin Zhang;
Li Chen

Publication type:

Article

CD22ΔE12 as a molecular target for RNAi therapy.

Published in:

British Journal of Haematology, 2015, v. 169, n. 3, p. 401, doi. 10.1111/bjh.13306

By:

Uckun, Fatih M.;
Ma, Hong;
Cheng, Jianjun;
Myers, Dorothea E.;
Qazi, Sanjive

Publication type:

Article

Comparative Transcriptome Analyses Uncover Key Candidate Genes Mediating Flight Capacity in Bactrocera dorsalis (Hendel) and Bactrocera correcta (Bezzi) (Diptera: Tephritidae).

Published in:

International Journal of Molecular Sciences, 2018, v. 19, n. 2, p. 396, doi. 10.3390/ijms19020396

By:

Guo, Shaokun;
Zhao, Zihua;
Liu, Lijun;
Li, Zhihong;
Shen, Jie

Publication type:

Article

Development of Small RNA Delivery Systems for Lung Cancer Therapy.

Published in:

International Journal of Molecular Sciences, 2015, v. 16, n. 3, p. 5254, doi. 10.3390/ijms16035254

By:

Yu Fujita;
Kazuyoshi Kuwano;
Takahiro Ochiya

Publication type:

Article

Zilebesiran Reduces SBP on Background SOC in Uncontrolled HTN: Daily Dose.

Published in:

Patient Care (Online), 2024, p. 1

By:

Jennings, Sydney

Publication type:

Article