Works matching DE "KINASES"

Results: 3072

Overexpression of SIK2 Inhibits FGF2-dependent Müller Glial Reprogramming.

Published in:

Experimed, 2025, v. 15, n. 1, p. 23, doi. 10.26650/experimed.1536826

By:

Bayarslan, Asli Ugurlu;
Bugra, Kuyas

Publication type:

Article

Research progress on the therapeutic effects of effective components of traditional Chinese medicine in the treatment of gastric cancer precursors through modulation of multiple signaling pathways.

Published in:

Frontiers in Oncology, 2025, p. 1, doi. 10.3389/fonc.2025.1555274

By:

Han, Lichao;
Ma, Yijia;
Wu, Weidong;
Ni, Qianyue;
Xie, Jingri;
Huang, Yan;
Jin, Qiuyu;
Wu, Lili;
Zhang, Yang

Publication type:

Article

Rice receptor kinase FLR7 regulates rhizosphere oxygen levels and enriches the dominant Anaeromyxobacter that improves submergence tolerance in rice.

Published in:

ISME Journal: Multidisciplinary Journal of Microbial Ecology, 2024, v. 18, n. 1, p. 1, doi. 10.1093/ismejo/wrae006

By:

Liu, Hong-Bin;
Sun, Hong-Xia;
Du, Li-Qiong;
Jiang, Ling-Li;
Zhang, Lin-An;
Qi, Yin-Yao;
Cai, Jun;
Yu, Feng

Publication type:

Article

JAK-cytokine receptor recognition, unboxed.

Published in:

Nature Structural & Molecular Biology, 2014, v. 21, n. 5, p. 431, doi. 10.1038/nsmb.2824

By:

McNally, Randall;
Eck, Michael J

Publication type:

Article

Plant pathogens: Oomycete kinase blights potatoes.

Published in:

Nature Reviews Microbiology, 2012, v. 10, n. 10, p. 672, doi. 10.1038/nrmicro2884

By:

Jermy, Andrew

Publication type:

Article

Isoform‐Selective Fluorescent Labeling of 14‐3‐3σ by Acrylamide‐Containing Fusicoccins.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 41, p. 1, doi. 10.1002/chem.202301059

By:

Tanaka, Kenta;
Hatano, Yoshiya;
Ohkanda, Junko

Publication type:

Article

Rational Design and Synthesis of D‐galactosyl Lysophospholipids as Selective Substrates and non‐ATP‐competitive Inhibitors of Phosphatidylinositol Phosphate Kinases.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 2, p. 1, doi. 10.1002/chem.202202083

By:

Sun, Mengxia;
Zhang, Chi;
Sui, Dexin;
Yang, Canchai;
Pyeon, Dohun;
Huang, Xuefei;
Hu, Jian

Publication type:

Article

Late‐Stage Modification of Aminoglycoside Antibiotics Overcomes Bacterial Resistance Mediated by APH(3') Kinases.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 36, p. 1, doi. 10.1002/chem.202200883

By:

Bastian, Andreas A.;
Bastian, Maria;
Jäger, Manuel;
Loznik, Mark;
Warszawik, Eliza M.;
Yang, Xintong;
Tahiri, Nabil;
Fodran, Peter;
Witte, Martin D.;
Thoma, Anne;
Köhler, Jens;
Minnaard, Adriaan J.;
Herrmann, Andreas

Publication type:

Article

Modulation of Src Kinase Activity by Selective Substrate Recognition with Pseudopeptidic Cages.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 37, p. 9542, doi. 10.1002/chem.202100990

By:

Tapia, Lucía;
Solozabal, Naiara;
Solà, Jordi;
Pérez, Yolanda;
Miller, W. Todd;
Alfonso, Ignacio

Publication type:

Article

Cover Feature: Modulation of Src Kinase Activity by Selective Substrate Recognition with Pseudopeptidic Cages (Chem. Eur. J. 37/2021).

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 37, p. 9462, doi. 10.1002/chem.202101933

By:

Tapia, Lucía;
Solozabal, Naiara;
Solà, Jordi;
Pérez, Yolanda;
Miller, W. Todd;
Alfonso, Ignacio

Publication type:

Article

Neuritogenic Militarinone-Inspired 4-Hydroxypyridones Target the Stress Pathway Kinase MAP4K4.

Published in:

Angewandte Chemie, 2015, v. 127, n. 42, p. 12575, doi. 10.1002/ange.201501515

By:

Schröder, Peter;
Förster, Tim;
Kleine, Stefan;
Becker, Christian;
Richters, André;
Ziegler, Slava;
Rauh, Daniel;
Kumar, Kamal;
Waldmann, Herbert

Publication type:

Article

Turning Tryptophanase into Odor-Generating Biosensors.

Published in:

Angewandte Chemie, 2014, v. 126, n. 10, p. 2658, doi. 10.1002/ange.201309684

By:

Xu, Yaqin;
Zhang, Zhuyuan;
Ali, M. Monsur;
Sauder, Joanna;
Deng, Xudong;
Giang, Karen;
Aguirre, Sergio D.;
Pelton, Robert;
Li, Yingfu;
Filipe, Carlos D. M.

Publication type:

Article

Ein metallorganischer Inhibitor des humanen Reparaturenzyms 7,8-Dihydro-8-oxoguanosin-Triphosphatase.

Published in:

Angewandte Chemie, 2014, v. 126, n. 1, p. 311, doi. 10.1002/ange.201307849

By:

Streib, Manuel;
Kräling, Katja;
Richter, Kristin;
Xie, Xiulan;
Steuber, Holger;
Meggers, Eric

Publication type:

Article

Top-Beiträge aus unseren Schwesterzeitschriften: Angew. Chem. 45/2013.

Published in:: Angewandte Chemie, 2013, v. 125, n. 45, p. 11904, doi. 10.1002/ange.201384513
Publication type:: Article

UMP kinase activity is involved in proper chloroplast development in rice.

Published in:

Photosynthesis Research, 2018, v. 137, n. 1, p. 53, doi. 10.1007/s11120-017-0477-5

By:

Chen, Fei;
Dong, Guojun;
Ma, Xiaohui;
Wang, Fang;
Zhang, Yanli;
Xiong, Erhui;
Wu, Jiahuan;
Wang, Huizhong;
Qian, Qian;
Wu, Limin;
Yu, Yanchun

Publication type:

Article

Interplay between paclitaxel, gap junctions, and kinases: unraveling mechanisms of action and resistance in cancer therapy.

Published in:

Molecular Biology Reports, 2024, v. 51, n. 1, p. 1, doi. 10.1007/s11033-024-09411-x

By:

Moon, Dong-Oh

Publication type:

Article

The secreted lipase FGL1 is sufficient to restore the initial infection step to the apathogenic Fusarium graminearum MAP kinase disruption mutant Δgpmk1.

Published in:

European Journal of Plant Pathology, 2012, v. 134, n. 1, p. 23, doi. 10.1007/s10658-012-0017-2

By:

Salomon, Siegfried;
Gácser, Attila;
Frerichmann, Sebastian;
Kröger, Cathrin;
Schäfer, Wilhelm;
Voigt, Christian

Publication type:

Article

Zinc regulates the activity of kinase-phosphatase pair (BasPrkC/BasPrpC) in Bacillus anthracis.

Published in:

BioMetals, 2013, v. 26, n. 5, p. 715, doi. 10.1007/s10534-013-9646-y

By:

Arora, Gunjan;
Sajid, Andaleeb;
Arulanandh, Mary;
Misra, Richa;
Singhal, Anshika;
Kumar, Santosh;
Singh, Lalit;
Mattoo, Abid;
Raj, Rishi;
Maiti, Souvik;
Basu-Modak, Sharmila;
Singh, Yogendra

Publication type:

Article

Catalytic and regulatory roles of species involved in metal-nucleotide equilibriums in human pyridoxal kinase.

Published in:

BioMetals, 2013, v. 26, n. 5, p. 805, doi. 10.1007/s10534-013-9660-0

By:

Navarro, Freddy;
Ramírez-Sarmiento, César;
Guixé, Victoria

Publication type:

Article

Advances in reversible covalent kinase inhibitors.

Published in:

Medicinal Research Reviews, 2025, v. 45, n. 2, p. 629, doi. 10.1002/med.22084

By:

Zhao, Zheng;
Bourne, Philip E.

Publication type:

Article

Mechanism of epithelial‐mesenchymal transition in cancer and its regulation by natural compounds.

Published in:

Medicinal Research Reviews, 2023, v. 43, n. 4, p. 1141, doi. 10.1002/med.21948

By:

Ang, Hui Li;
Mohan, Chakrabhavi Dhananjaya;
Shanmugam, Muthu K.;
Leong, Hin Chong;
Makvandi, Pooyan;
Rangappa, Kanchugarakoppal S.;
Bishayee, Anupam;
Kumar, Alan Prem;
Sethi, Gautam

Publication type:

Article

The RISK pathway and beyond.

Published in:

Basic Research in Cardiology, 2018, v. 113, n. 1, p. 1, doi. 10.1007/s00395-017-0662-x

By:

Rossello, Xavier;
Yellon, Derek M.

Publication type:

Article

Selective inhibition of inositol hexakisphosphate kinases (IP6Ks) enhances mesenchymal stem cell engraftment and improves therapeutic efficacy for myocardial infarction.

Published in:

Basic Research in Cardiology, 2014, v. 109, n. 4, p. 1, doi. 10.1007/s00395-014-0417-x

By:

Zhang, Zheng;
Liang, Dong;
Gao, Xue;
Zhao, Chuanxu;
Qin, Xing;
Xu, Yong;
Su, Tao;
Sun, Dongdong;
Li, Weijie;
Wang, Haichang;
Liu, Bing;
Cao, Feng

Publication type:

Article

The effects of curcumin post-treatment against myocardial ischemia and reperfusion by activation of the JAK2/STAT3 signaling pathway.

Published in:

Basic Research in Cardiology, 2012, v. 107, n. 3, p. 1, doi. 10.1007/s00395-012-0263-7

By:

Duan, Weixun;
Yang, Yang;
Yan, Juanjuan;
Yu, Shiqiang;
Liu, Jincheng;
Zhou, Jingjun;
Zhang, Jianying;
Jin, Zhenxiao;
Yi, Dinghua

Publication type:

Article

Angiopoietin-4 expression and potential mechanisms in carcinogenesis: Current achievements and perspectives.

Published in:

Clinical & Experimental Medicine, 2024, v. 24, n. 1, p. 1, doi. 10.1007/s10238-024-01449-2

By:

Zhou, Wenchao;
Zhang, Qunfeng;
Chen, Junling;
Gan, Jinpeng;
Li, Yukun;
Zou, Juan

Publication type:

Article

Molecular insight into the affinity, specificity and cross-reactivity of systematic hepatocellular carcinoma RALT interaction profile with human receptor tyrosine kinases.

Published in:

Amino Acids, 2021, v. 53, n. 11, p. 1715, doi. 10.1007/s00726-021-03083-8

By:

Lu, Guang;
Li, Xiaoping;
Zhang, Jun;
Xu, Qinghua

Publication type:

Article

Study of cross talk between phosphatases and OGA on a ZO-3-derived peptide.

Published in:

Amino Acids, 2019, v. 51, n. 4, p. 739, doi. 10.1007/s00726-019-02699-1

By:

Sharif, Suhela;
Shi, Jie;
Ruijtenbeek, Rob;
Pieters, Roland J.

Publication type:

Article

Ser/Thr kinases and polyamines in the regulation of non-canonical functions of elongation factor 1A.

Published in:

Amino Acids, 2016, v. 48, n. 10, p. 2339, doi. 10.1007/s00726-016-2311-3

By:

Migliaccio, Nunzia;
Martucci, Nicola;
Ruggiero, Immacolata;
Sanges, Carmen;
Ohkubo, Shinji;
Lamberti, Annalisa;
Agostinelli, Enzo;
Arcari, Paolo

Publication type:

Article

Traf2- and Nck-interacting kinase (TNIK) is involved in the anti-cancer mechanism of dovitinib in human multiple myeloma IM-9 cells.

Published in:

Amino Acids, 2016, v. 48, n. 7, p. 1591, doi. 10.1007/s00726-016-2214-3

By:

Chon, Hae;
Lee, Yura;
Bae, Kyoung;
Byun, Byung;
Kim, Soon;
Kim, Jiyeon

Publication type:

Article

Site-directed mutagenesis and feedback-resistant N-acetyl- L-glutamate kinase (NAGK) increase Corynebacterium crenatum L-arginine production.

Published in:

Amino Acids, 2012, v. 43, n. 1, p. 255, doi. 10.1007/s00726-011-1069-x

By:

Xu, Meijuan;
Rao, Zhiming;
Dou, Wenfang;
Yang, Juan;
Jin, Jian;
Xu, Zhenghong

Publication type:

Article

Activating mutations drive human MEK1 kinase using a gear-shifting mechanism.

Published in:

Biochemical Journal, 2023, v. 480, n. 21, p. 1733, doi. 10.1042/BCJ20230281

By:

Patil, Keshav;
Yiming Wang;
Zhangtao Chen;
Suresh, Krishna;
Radhakrishnan, Ravi

Publication type:

Article

The choreography of protein kinase PDK1 and its diverse substrate dance partners.

Published in:

Biochemical Journal, 2023, v. 480, n. 19, p. 1503, doi. 10.1042/BCJ20220396

By:

Leroux, Alejandro E.;
Biondi, Ricardo M.

Publication type:

Article

How many kinases are druggable? A review of our current understanding.

Published in:

Biochemical Journal, 2023, v. 480, n. 16, p. 1331, doi. 10.1042/BCJ20220217

By:

Anderson, Brian;
Rosston, Peter;
Han Wee Ong;
Hossain, Mohammad Anwar;
Davis-Gilbert, Zachary W.;
Drewry, David H.

Publication type:

Article

Dimerization and autophosphorylation of the MST family of kinases are controlled by the same set of residues.

Published in:

Biochemical Journal, 2023, v. 480, n. 15, p. 1165, doi. 10.1042/BCJ20230067

By:

Weingartner, Kyler A.;
Tran, Thao;
Tripp, Katherine W.;
Kavran, Jennifer M.

Publication type:

Article

Protein kinase C showcases allosteric control: activation of LRRK1.

Published in:

Biochemical Journal, 2023, v. 480, n. 3, p. 219, doi. 10.1042/BCJ20220507

By:

Tovell, Hannah;
Newton, Alexandra C.

Publication type:

Article

Evolutionary and cellular analysis of the 'dark' pseudokinase PSKH2.

Published in:

Biochemical Journal, 2023, v. 480, n. 2, p. 141, doi. 10.1042/BCJ20220474

By:

Byrne, Dominic P.;
Shrestha, Safal;
Daly, Leonard A.;
Marensi, Vanessa;
Ramakrishnan, Krithika;
Eyers, Claire E.;
Kannan, Natarajan;
Eyers, Patrick A.

Publication type:

Article

AMP-activated protein kinase -- a journey from 1 to 100 downstream targets.

Published in:

Biochemical Journal, 2022, v. 479, n. 22, p. 2327, doi. 10.1042/BCJ20220255

By:

Grahame Hardie, D.

Publication type:

Article

TOR complex 2 is a master regulator of plasma membrane homeostasis.

Published in:

Biochemical Journal, 2022, v. 479, n. 17, p. 1917, doi. 10.1042/BCJ20220388

By:

Thorner, Jeremy

Publication type:

Article

PKC isoforms activate LRRK1 kinase by phosphorylating conserved residues (Ser1064, Ser1074 and Thr1075) within the COR<sub>B</sub> GTPase domain.

Published in:

Biochemical Journal, 2022, v. 479, n. 18, p. 1941, doi. 10.1042/BCJ20220308

By:

Malik, Asad U.;
Karapetsas, Athanasios;
Nirujogi, Raja S.;
Chatterjee, Deep;
Phung, Toan K.;
Wightman, Melanie;
Gourlay, Robert;
Morrice, Nick;
Mathea, Sebastian;
Knapp, Stefan;
Alessi, Dario R.

Publication type:

Article

Mutation of the RelA(p65) Thr505 phosphosite disrupts the DNA replication stress response leading to CHK1 inhibitor resistance.

Published in:

Biochemical Journal, 2022, v. 479, n. 19, p. 2087, doi. 10.1042/BCJ20220089

By:

Hunter, Jill E.;
Campbell, Amy E.;
Butterworth, Jacqueline A.;
Sellier, Helene;
Hannaway, Nicola L.;
Luli, Saimir;
Floudas, Achilleas;
Kenneth, Niall S.;
Moore, Adam J.;
Brownridge, Philip J.;
Thomas, Huw D.;
Coxhead, Jonathan;
Taylor, Leigh;
Leary, Peter;
Hasoon, Megan S. R.;
Knight, Andrew M.;
Garrett, Michelle D.;
Collins, Ian;
Eyers, Claire E.;
Perkins, Neil D.

Publication type:

Article

TOR complex 2 is a master regulator of plasma membrane homeostasis.

Published in:

Biochemical Journal, 2022, v. 479, n. 18, p. 1917, doi. 10.1042/BCJ20220388

By:

Thorner, Jeremy

Publication type:

Article

PKC isoforms activate LRRK1 kinase by phosphorylating conserved residues (Ser1064, Ser1074 and Thr1075) within the COR<sub>B</sub> GTPase domain.

Published in:

Biochemical Journal, 2022, v. 479, n. 17, p. 1941, doi. 10.1042/BCJ20220308

By:

Malik, Asad U.;
Karapetsas, Athanasios;
Nirujogi, Raja S.;
Chatterjee, Deep;
Phung, Toan K.;
Wightman, Melanie;
Gourlay, Robert;
Morrice, Nick;
Mathea, Sebastian;
Knapp, Stefan;
Alessi, Dario R.

Publication type:

Article

Structure-function analysis of the AMPK activator SC4 and identification of a potent pan AMPK activator.

Published in:

Biochemical Journal, 2022, v. 479, n. 11, p. 1181, doi. 10.1042/BCJ20220067

By:

Ovens, Ashley J.;
Yi Sing Gee;
Ling, Naomi X. Y.;
Dingyi Yu;
Hardee, Justin P.;
Chung, Jin D.;
Ngoei, Kevin R. W.;
Waters, Nicholas J.;
Hoffman, Nolan J.;
Scott, John W.;
Kim Loh;
Spengler, Katrin;
Heller, Regine;
Parker, Michael W.;
Lynch, Gordon S.;
Fei Huang;
Galic, Sandra;
Kemp, Bruce E.;
Baell, Jonathan B.;
Oakhill, Jonathan S.

Publication type:

Article

Alphabetti kinase Spaghetti: the complex roles of IKKα and β in the canonical NF-κB pathway.

Published in:

Biochemical Journal, 2022, v. 479, n. 11, p. 1121, doi. 10.1042/BCJ20220023

By:

Perkins, Neil D.

Publication type:

Article

RIP1 post-translational modifications.

Published in:

Biochemical Journal, 2022, v. 479, n. 9, p. 929, doi. 10.1042/BCJ20210725

By:

Varfolomeev, Eugene;
Vucic, Domagoj

Publication type:

Article

Sequence and structural variations determining the recruitment of WNK kinases to the KLHL3 E3 ligase.

Published in:

Biochemical Journal, 2022, v. 479, n. 5, p. 661, doi. 10.1042/BCJ20220019

By:

Zhuoyao Chen;
Jinwei Zhang;
Murillo-de-Ozores, Adrián R.;
Castañeda-Bueno, María;
D'Amico, Francesca;
Heilig, Raphael;
Manning, Charlotte E.;
Sorrell, Fiona J.;
D'Angiolella, Vincenzo;
Fischer, Roman;
Mulder, Monique P. C.;
Gamba, Gerardo;
Alessi, Dario R.;
Bullock, Alex N.

Publication type:

Article

Kinases leave their mark on caspase substrates.

Published in:

Biochemical Journal, 2021, v. 478, n. 17, p. 3179, doi. 10.1042/BCJ20210399

By:

Weeks, Amy M.

Publication type:

Article

Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965.

Published in:

Biochemical Journal, 2021, v. 478, n. 15, p. 2977, doi. 10.1042/BCJ20210284

By:

Ahwazi, Danial;
Neopane, Katyayanee;
Markby, Greg R.;
Kopietz, Franziska;
Ovens, Ashley J.;
Dall, Morten;
Hassing, Anna S.;
Gräsle, Pamina;
Alshuweishi, Yazeed;
Treebak, Jonas T.;
Salt, Ian P.;
Göransson, Olga;
Zeqiraj, Elton;
Scott, John W.;
Sakamoto, Kei

Publication type:

Article

Conformational plasticity of the ULK3 kinase domain.

Published in:

Biochemical Journal, 2021, v. 478, n. 14, p. 2811, doi. 10.1042/BCJ20210257

By:

Mathea, Sebastian;
Salah, Eidarus;
Tallant, Cynthia;
Chatterjee, Deep;
Berger, Benedict-Tilman;
Konietzny, Rebecca;
Müller, Susanne;
Kessler, Benedikt M.;
Knapp, Stefan

Publication type:

Article

Nuts and bolts of the salt-inducible kinases (SIKs).

Published in:

Biochemical Journal, 2021, v. 478, n. 7, p. 1377, doi. 10.1042/BCJ20200502

By:

Darling, Nicola J.;
Cohen, Philip

Publication type:

Article