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Systems toxicology study reveals reduced impact of heated tobacco product aerosol extract relative to cigarette smoke on premature aging and exacerbation effects in aged aortic cells in vitro.
- Published in:
- Archives of Toxicology, 2021, v. 95, n. 10, p. 3341, doi. 10.1007/s00204-021-03123-y
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- Publication type:
- Article
Evaluation of toxicity of aerosols from flavored e-liquids in Sprague–Dawley rats in a 90-day OECD inhalation study, complemented by transcriptomics analysis.
- Published in:
- Archives of Toxicology, 2020, v. 94, n. 6, p. 2179, doi. 10.1007/s00204-020-02759-6
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- Publication type:
- Article
Application of a multi-layer systems toxicology framework for in vitro assessment of the biological effects of Classic Tobacco e-liquid and its corresponding aerosol using an e-cigarette device with MESH™ technology.
- Published in:
- Archives of Toxicology, 2019, v. 93, n. 11, p. 3229, doi. 10.1007/s00204-019-02565-9
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- Publication type:
- Article
Genomic Insights into the Evolution of the Nicotine Biosynthesis Pathway in Tobacco.
- Published in:
- Plant Physiology, 2017, v. 174, n. 2, p. 999, doi. 10.1104/pp.17.00070
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- Publication type:
- Article
Anatabine ameliorates intestinal inflammation and reduces the production of pro-inflammatory factors in a dextran sulfate sodium mouse model of colitis.
- Published in:
- Journal of Inflammation, 2020, v. 17, n. 1, p. N.PAG, doi. 10.1186/s12950-020-00260-6
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- Publication type:
- Article
Design of a tobacco exon array with application to investigate the differential cadmium accumulation property in two tobacco varieties.
- Published in:
- BMC Genomics, 2012, v. 13, n. 1, p. 1, doi. 10.1186/1471-2164-13-674
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- Publication type:
- Article
Nicotiana noctiflora Hook. Genome Contains Two Cellular T-DNAs with Functional Genes.
- Published in:
- Plants (2223-7747), 2023, v. 12, n. 22, p. 3787, doi. 10.3390/plants12223787
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- Publication type:
- Article
Systems biology reveals anatabine to be an NRF2 activator.
- Published in:
- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.1011184
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- Publication type:
- Article
Phage T7 DNA mimic protein Ocr is a potent inhibitor of BREX defence.
- Published in:
- Nucleic Acids Research, 2020, v. 48, n. 13, p. 7601, doi. 10.1093/nar/gkaa510
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- Publication type:
- Article
Phage T7 DNA mimic protein Ocr is a potent inhibitor of BREX defence.
- Published in:
- Nucleic Acids Research, 2020, v. 48, n. 10, p. 5397, doi. 10.1093/nar/gkaa290
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- Publication type:
- Article
BREX system of Escherichia coli distinguishes self from non-self by methylation of a specific DNA site.
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- Nucleic Acids Research, 2019, v. 47, n. 1, p. 253, doi. 10.1093/nar/gky1125
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- Publication type:
- Article
Pulmonary Delivery of Aerosolized Chloroquine and Hydroxychloroquine to Treat COVID-19: In Vitro Experimentation to Human Dosing Predictions.
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- AAPS Journal, 2022, v. 24, n. 1, p. 1, doi. 10.1208/s12248-021-00666-x
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- Publication type:
- Article
Fractionation and Extraction Optimization of Potentially Valuable Compounds and Their Profiling in Six Varieties of Two Nicotiana Species.
- Published in:
- Molecules, 2022, v. 27, n. 22, p. 8105, doi. 10.3390/molecules27228105
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- Publication type:
- Article
Impact of whole‐body versus nose‐only inhalation exposure systems on systemic, respiratory, and cardiovascular endpoints in a 2‐month cigarette smoke exposure study in the ApoE<sup>−/−</sup> mouse model.
- Published in:
- Journal of Applied Toxicology, 2021, v. 41, n. 10, p. 1598, doi. 10.1002/jat.4149
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- Publication type:
- Article
PYL1- and PYL8-like ABA Receptors of Nicotiana benthamiana Play a Key Role in ABA Response in Seed and Vegetative Tissue.
- Published in:
- Cells (2073-4409), 2022, v. 11, n. 5, p. 795, doi. 10.3390/cells11050795
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- Publication type:
- Article
Impact of 6-Month Exposure to Aerosols From Potential Modified Risk Tobacco Products Relative to Cigarette Smoke on the Rodent Gastrointestinal Tract.
- Published in:
- Frontiers in Microbiology, 2021, v. 12, p. 1, doi. 10.3389/fmicb.2021.587745
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- Publication type:
- Article
Reference genomes and transcriptomes of Nicotiana sylvestris and Nicotiana tomentosiformis.
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- Genome Biology, 2013, v. 14, n. 6, p. 1, doi. 10.1186/gb-2013-14-6-r60
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- Publication type:
- Article
A lower impact of an acute exposure to electronic cigarette aerosols than to cigarette smoke in human organotypic buccal and small airway cultures was demonstrated using systems toxicology assessment.
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- 2019
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- Publication type:
- journal article
GladiaTOX: GLobal Assessment of Dose-IndicAtor in TOXicology.
- Published in:
- Bioinformatics, 2019, v. 35, n. 20, p. 4190, doi. 10.1093/bioinformatics/btz187
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- Publication type:
- Article
Understanding the limits of animal models as predictors of human biology: lessons learned from the sbv IMPROVER Species Translation Challenge.
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- Bioinformatics, 2015, v. 31, n. 4, p. 471, doi. 10.1093/bioinformatics/btu611
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- Publication type:
- Article
SolCyc: a database hub at the Sol Genomics Network (SGN) for the manual curation of metabolic networks in Solanum and Nicotiana specific databases.
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- Database: The Journal of Biological Databases & Curation, 2018, v. 2018, p. 1, doi. 10.1093/database/bay035
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- Publication type:
- Article
3D Human Microvessel-on-a-Chip Model for Studying Monocyte-to-Endothelium Adhesion under Flow - Application in Systems Toxicology.
- Published in:
- Altex, 2020, v. 37, n. 1, p. 47, doi. 10.14573/altex.1811301
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- Publication type:
- Article
How Complex Should an In Vitro Model Be? Evaluation of a Complex 3D Alveolar Model with Transcriptomic Data and Computational Biological Network Models.
- Published in:
- Altex, 2019, v. 36, n. 3, p. 388, doi. 10.14573/altex.1811221
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- Publication type:
- Article
3-D Nasal Cultures: Systems Toxicological Assessment of a Candidate Modified-Risk Tobacco Product.
- Published in:
- Altex, 2017, v. 34, n. 1, p. 23, doi. 10.14573/altex.1605041
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- Publication type:
- Article
Crowdsourced benchmarking of taxonomic metagenome profilers: lessons learned from the sbv IMPROVER Microbiomics challenge.
- Published in:
- BMC Genomics, 2022, v. 23, n. 1, p. 1, doi. 10.1186/s12864-022-08803-2
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- Publication type:
- Article
A Topologist's View of the Dunford-Schwartz Proof of the Brouwer Fixed-Point Theorem.
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- Mathematical Intelligencer, 2000, v. 22, n. 3, p. 55, doi. 10.1007/BF03025284
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- Publication type:
- Article
Chromosome-level genome assemblies of Nicotiana tabacum, Nicotiana sylvestris, and Nicotiana tomentosiformis.
- Published in:
- Scientific Data, 2024, v. 11, n. 1, p. 1, doi. 10.1038/s41597-024-02965-2
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- Publication type:
- Article
Automorphism of complexes of curves and of Teichmüller spaces.
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- IMRN: International Mathematics Research Notices, 1997, v. 1997, n. 14, p. 651, doi. 10.1155/S1073792897000433
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- Publication type:
- Article
Analysis of chemical deposits on tooth enamel exposed to total particulate matter from cigarette smoke and tobacco heating system 2.2 aerosol by novel GC–MS deconvolution procedures.
- Published in:
- Romanian Journal of Stomatology / Revista Romana de Stomatologie, 2020, v. 66, n. 3, p. 207, doi. 10.1016/j.jchromb.2020.122228
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- Publication type:
- Article
Comparative systems toxicology analysis of cigarette smoke and aerosol from a candidate modified risk tobacco product in organotypic human gingival epithelial cultures: A 3-day repeated exposure study.
- Published in:
- Romanian Journal of Stomatology / Revista Romana de Stomatologie, 2019, v. 65, n. 2, p. 15, doi. 10.1016/j.fct.2016.12.027
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- Publication type:
- Article
Respiratory Effects of Exposure to Aerosol From the Candidate Modified-Risk Tobacco Product THS 2.2 in an 18-Month Systems Toxicology Study With A/J Mice.
- Published in:
- Toxicological Sciences, 2020, v. 178, n. 1, p. 138, doi. 10.1093/toxsci/kfaa132
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- Publication type:
- Article
An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe<sup>-/-</sup> Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Product, THS 2.2, Compared With Conventional Cigarettes.
- Published in:
- Toxicological Sciences, 2016, v. 149, n. 2, p. 411, doi. 10.1093/toxsci/kfv243
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- Publication type:
- Article
Impact Assessment of Cigarette Smoke Exposure on Organotypic Bronchial Epithelial Tissue Cultures: A Comparison of Mono-Culture and Coculture Model Containing Fibroblasts.
- Published in:
- Toxicological Sciences, 2015, v. 147, n. 1, p. 207, doi. 10.1093/toxsci/kfv122
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- Publication type:
- Article
Comparative effects of a candidate modified-risk tobacco product Aerosol and cigarette smoke on human organotypic small airway cultures: a systems toxicology approach.
- Published in:
- Toxicology Research, 2017, v. 6, n. 6, p. 930, doi. 10.1039/c7tx00152e
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- Publication type:
- Article
Results and lessons learned from the sbv IMPROVER metagenomics diagnostics for inflammatory bowel disease challenge.
- Published in:
- Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-33050-0
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- Publication type:
- Article
The tobacco genome sequence and its comparison with those of tomato and potato.
- Published in:
- Nature Communications, 2014, v. 5, n. 5, p. 3833, doi. 10.1038/ncomms4833
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- Publication type:
- Article
A Meta-Analysis of the Performance of a Blood-Based Exposure Response Gene Signature Across Clinical Studies on the Tobacco Heating System 2.2 (THS 2.2).
- Published in:
- Romanian Medical Journal, 2019, v. 66, n. 2, p. 174, doi. 10.3389/fphar.2019.00198
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- Publication type:
- Article
Evaluation of the Tobacco Heating System 2.2. Part 4: 90-day OECD 413 rat inhalation study with systems toxicology endpoints demonstrates reduced exposure effects compared with cigarette smoke.
- Published in:
- Romanian Medical Journal, 2019, v. 66, n. 1, p. 70, doi. 10.1016/j.yrtph.2016.10.015
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- Publication type:
- Article
A Meta-Analysis of the Performance of a Blood-Based Exposure Response Gene Signature Across Clinical Studies on the Tobacco Heating System 2.2 (THS 2.2).
- Published in:
- Frontiers in Pharmacology, 2019, p. N.PAG, doi. 10.3389/fphar.2019.00198
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- Publication type:
- Article
Organization of the TC and TE cellular T‐DNA regions in <italic>Nicotiana otophora</italic> and functional analysis of three diverged TE‐<italic>6b</italic> genes.
- Published in:
- Plant Journal, 2018, v. 94, n. 2, p. 274, doi. 10.1111/tpj.13853
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- Publication type:
- Article
Whole genome profiling physical map and ancestral annotation of tobacco Hicks Broadleaf.
- Published in:
- Plant Journal, 2013, v. 75, n. 5, p. 880, doi. 10.1111/tpj.12247
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- Publication type:
- Article
Polyploid Nicotiana section Suaveolentes originated by hybridization of two ancestral Nicotiana clades.
- Published in:
- Frontiers in Plant Science, 2023, p. 1, doi. 10.3389/fpls.2023.999887
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- Publication type:
- Article
Natural and induced variations in transcriptional regulator genes result in low‐nicotine phenotypes in tobacco.
- Published in:
- Plant Journal, 2022, v. 111, n. 6, p. 1768, doi. 10.1111/tpj.15923
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- Publication type:
- Article
Inhibition of Arabidopsis thaliana CIN‐like TCP transcription factors by Agrobacterium T‐DNA‐encoded 6B proteins.
- Published in:
- Plant Journal, 2020, v. 101, n. 6, p. 1303, doi. 10.1111/tpj.14591
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- Publication type:
- Article
Suppression of pyrrolidine ring biosynthesis and its effects on gene expression and subsequent accumulation of anatabine in leaves of tobacco (N. tabacum L.).
- Published in:
- BMC Genomics, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12864-023-09588-8
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- Publication type:
- Article
Metabolic networks of the Nicotiana genus in the spotlight: content, progress and outlook.
- Published in:
- Briefings in Bioinformatics, 2021, v. 22, n. 3, p. 1, doi. 10.1093/bib/bbaa136
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- Publication type:
- Article
The reduction of DSS-induced colitis severity in mice exposed to cigarette smoke is linked to immune modulation and microbial shifts.
- Published in:
- Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-020-60175-3
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- Publication type:
- Article
Chromosome-scale assemblies of S. malaccense, S. aqueum, S. jambos, and S. syzygioides provide insights into the evolution of Syzygium genomes.
- Published in:
- Frontiers in Plant Science, 2023, p. 1, doi. 10.3389/fpls.2023.1248780
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- Publication type:
- Article
Verification of systems biology research in the age of collaborative competition.
- Published in:
- 2011
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- Publication type:
- Opinion
Proteomics and Lipidomics in Inflammatory Bowel Disease Research: From Mechanistic Insights to Biomarker Identification.
- Published in:
- International Journal of Molecular Sciences, 2018, v. 19, n. 9, p. 2775, doi. 10.3390/ijms19092775
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- Publication type:
- Article