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Title: Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists.
Authors: Seow, Vernon; Lim, Junxian; Cotterell, Adam J.; Yau, Mei-Kwan; Xu, Weijun; Lohman, Rink-Jan; Kok, W. Mei; Stoermer, Martin J.; Sweet, Matthew J.; Reid, Robert C.; Suen, Jacky Y.; Fairlie, David P.
Publication: Scientific Reports, 2016, p24575
ISSN: 2045-2322
Publication type: Academic Journal
DOI: 10.1038/srep24575

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Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists.