Works matching DE "PEPTIDE deformylase"

Results: 16

Synthesis of the intermediate for fumimycin: a natural peptide deformylase inhibitor.

Published in:

Research on Chemical Intermediates, 2013, v. 39, n. 7, p. 3049, doi. 10.1007/s11164-012-0817-1

By:

Zhou, Zhi-Wang;
Li, Wei-Chao;
Hu, Yu;
Wang, Bin;
Ren, Gang;
Feng, Li-Hua

Publication type:

Article

Dynamic enzyme docking to the ribosome coordinates N-terminal processing with polypeptide folding.

Published in:

Nature Structural & Molecular Biology, 2013, v. 20, n. 7, p. 843, doi. 10.1038/nsmb.2615

By:

Sandikci, Arzu;
Gloge, Felix;
Martinez, Michael;
Mayer, Matthias P;
Wade, Rebecca;
Bukau, Bernd;
Kramer, Günter

Publication type:

Article

Structure-Based Drug Design of Small Molecule Peptide Deformylase Inhibitors to Treat Cancer.

Published in:

Molecules, 2016, v. 21, n. 4, p. 396, doi. 10.3390/molecules21040396

By:

Jian Gao;
Tao Wang;
Shengzhi Qiu;
Yasheng Zhu;
Li Liang;
Youguang Zheng

Publication type:

Article

Structure and function of a cyanophage-encoded peptide deformylase.

Published in:

ISME Journal: Multidisciplinary Journal of Microbial Ecology, 2013, v. 7, n. 6, p. 1150, doi. 10.1038/ismej.2013.4

By:

Frank, Jeremy A;
Lorimer, Don;
Youle, Merry;
Witte, Pam;
Craig, Tim;
Abendroth, Jan;
Rohwer, Forest;
Edwards, Robert A;
Segall, Anca M;
Burgin, Alex B

Publication type:

Article

How water molecules affect the catalytic activity of hydrolases - A XANES study of the local structures of peptide deformylase.

Published in:

Scientific Reports, 2014, p. 1, doi. 10.1038/srep07453

By:

Peixin Cui;
Yu Wang;
Wangsheng Chu;
Xiaoyun Guo;
Feifei Yang;
Meijuan Yu;
Haifeng Zhao;
Yuhui Dong;
Yaning Xie;
Weimin Gong;
Ziyu Wu

Publication type:

Article

The Inhibition and Resistance Mechanisms of Actinonin, Isolated from Marine Streptomyces sp. NHF165, against Vibrio anguillarum.

Published in:

Frontiers in Microbiology, 2016, p. 1, doi. 10.3389/fmicb.2016.01467

By:

Na Yang;
Chaomin Sun

Publication type:

Article

A concise synthesis of (±)-methoxyfumimycin ethyl ester.

Published in:

Journal of Chemical Research, 2014, v. 38, n. 6, p. 378, doi. 10.3184/174751914X14011142030158

By:

Zhou, Zhiwang;
Hu, Yu;
Wang, Bin;
He, Xiaoru;
Ren, Gang;
Feng, Lihua

Publication type:

Article

Peptide deformylase inhibitor actinonin reduces celastrol's HSP70 induction while synergizing proliferation inhibition in tumor cells.

Published in:

BMC Cancer, 2014, v. 14, p. 1, doi. 10.1186/1471-2407-14-146

By:

Bin Peng;
Xue Zhang;
Fanfan Cao;
Ying Wang;
Limin Xu;
Lu Cao;
Chunxin Yang;
Maoquan Li;
Uzan, Georges;
Denghai Zhang

Publication type:

Article

Peptide deformylase inhibitor actinonin reduces celastrol's HSP70 induction while synergizing proliferation inhibition in tumor cells.

Published in:

BMC Cancer, 2014, v. 14, n. 1, p. 1, doi. 10.1186/1471-2407-14-146

By:

Bin Peng;
Xue Zhang;
Fanfan Cao;
Ying Wang;
Limin Xu;
Lu Cao;
Chunxin Yang;
Maoquan Li;
Georges Uzan;
Denghai Zhang

Publication type:

Article

Overexpression of peptide deformylase in breast, colon, and lung cancers.

Published in:

BMC Cancer, 2013, v. 13, n. 1, p. 1, doi. 10.1186/1471-2407-13-321

By:

Randhawa, Harsharan;
Chikara, Shireen;
Gehring, Drew;
Yildirim, Tuba;
Menon, Jyotsana;
Reindl, Katie M.

Publication type:

Article

Safety, tolerability and pharmacokinetics of repeat dosing of the antibiotic GSK1322322, a peptide deformylase inhibitor: a randomized placebo-controlled study.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2013, v. 68, n. 8, p. 1901, doi. 10.1093/jac/dkt097

By:

Naderer, Odin J.;
Dumont, Etienne;
Zhu, John;
Kurtinecz, Milena;
Jones, Lori S.

Publication type:

Article

New peptide deformylase inhibitors and cooperative interaction: a combination to improve antibacterial activity.

Published in:

Journal of Antimicrobial Chemotherapy (JAC), 2012, v. 67, n. 6, p. 1392, doi. 10.1093/jac/dks058

By:

Goemaere, Emilie;
Melet, Armelle;
Larue, Valéry;
Lieutaud, Aurélie;
Alves de Sousa, Rodolphe;
Chevalier, Jacqueline;
Yimga-Djapa, Liselotte;
Giglione, Carmela;
Huguet, Florian;
Alimi, Mickael;
Meinnel, Thierry;
Dardel, Frédéric;
Artaud, Isabelle;
Pagès, Jean-Marie

Publication type:

Article

Ligand and Structure-Based Approaches for the Identification of Peptide Deformylase Inhibitors as Antibacterial Drugs.

Published in:

International Journal of Molecular Sciences, 2016, v. 17, n. 7, p. 1141, doi. 10.3390/ijms17071141

By:

Jian Gao;
Li Liang;
Yasheng Zhu;
Shengzhi Qiu;
Tao Wang;
Ling Zhang

Publication type:

Article

Genome-Wide Identification and in Silico Analysis of Poplar Peptide Deformylases.

Published in:

International Journal of Molecular Sciences, 2012, v. 13, n. 4, p. 5112, doi. 10.3390/ijms13045112

By:

Chang-Cai Liu;
Bao-Guang Liu;
Zhi-Wei Yang;
Chun-Ming Li;
Bai-Chen Wang;
Chuan-Ping Yang

Publication type:

Article

The effect of food and formulation on the pharmacokinetics, safety, and tolerability of GSK1322322 in healthy volunteers.

Published in:

Clinical Pharmacology in Drug Development, 2015, v. 4, n. 1, p. 49, doi. 10.1002/cpdd.165

By:

Naderer, Odin;
Jones, Lori S.;
Zhu, John;
Coffin, Mark D.;
Kurtinecz, Milena;
Dumont, Etienne

Publication type:

Article

Design, Synthesis, and Antibacterial Activities of Novel Heterocyclic Arylsulphonamide Derivatives.

Published in:

Interdisciplinary Sciences: Computational Life Sciences, 2018, v. 10, n. 4, p. 748, doi. 10.1007/s12539-016-0207-2

By:

Singh, Anuradha;
Srivastava, Ritika;
Singh, Ramendra K.

Publication type:

Article