Works matching Tumor suppressor genes

Results: 5000

Epigenetic silencing of the LDOC1 tumor suppressor gene in ovarian cancer cells.

Published in:

Archives of Gynecology & Obstetrics, 2014, v. 290, n. 1, p. 149, doi. 10.1007/s00404-014-3177-9

By:

Buchholtz, Marie-Luise;
Brüning, Ansgar;
Mylonas, Ioannis;
Jückstock, Julia

Publication type:

Article

Loss of Heterozygosity at the 9p21-24 Region and Identification of BRM as a Candidate Tumor Suppressor Gene in Head and Neck Squamous Cell Carcinoma.

Published in:

Cancer Investigation, 2009, v. 27, n. 6, p. 661, doi. 10.1080/07357900802563010

By:

Gunduz, Esra;
Gunduz, Mehmet;
Ali, Mahmoud Al Sheik;
Beder, Levent;
Tamamura, Ryo;
Katase, Naoki;
Tominaga, Susumu;
Yamanaka, Noboru;
Shimizu, Kenji;
Nagatsuka, Hitoshi

Publication type:

Article

Membranoproliferative glomerulonephritis associated with a mutation in Wilms’ tumour suppressor gene 1.

Published in:

2009

By:

Bockenhauer, Detlef;
van't Hoff, William;
Chernin, Gil;
Heeringa, Saskia F.;
Sebire, Neil J.

Publication type:

Report

The RB1 Story: Characterization and Cloning of the First Tumor Suppressor Gene.

Published in:

Genes, 2019, v. 10, n. 11, p. 879, doi. 10.3390/genes10110879

By:

Berry, Jesse L.;
Polski, Ashley;
Cavenee, Webster K.;
Dryja, Thaddeus P.;
Murphree, A. Linn;
Gallie, Brenda L.

Publication type:

Article

Promoter Methylation of Four Tumor Suppressor Genes in Human Papillary Thyroid Carcinoma.

Published in:

Iranian Journal of Pathology, 2019, v. 14, n. 4, p. 290, doi. 10.30699/ijp.2019.94401.1922

By:

Khatami, Fatemeh;
Larijani, Bagher;
Heshmat, Ramin;
Nasiri, Shirzad;
Saffar, Hiva;
Shafiee, Gita;
Mossafa, Azam;
Tavangar, Seyed Mohammad

Publication type:

Article

Integrated Analysis of Somatic DNA Variants and DNA Methylation of Tumor Suppressor Genes in Colorectal Cancer.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 4, p. 1642, doi. 10.3390/ijms26041642

By:

Nishiki, Hisashi;
Ura, Hiroki;
Togi, Sumihito;
Hatanaka, Hisayo;
Fujita, Hideto;
Takamura, Hiroyuki;
Niida, Yo

Publication type:

Article

Pilot RNAi Screen in Drosophila Neural Stem Cell Lineages to Identify Novel Tumor Suppressor Genes Involved in Asymmetric Cell Division.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 21, p. 11332, doi. 10.3390/ijms222111332

By:

Manzanero-Ortiz, Sandra;
de Torres-Jurado, Ana;
Hernández-Rojas, Rubí;
Carmena, Ana

Publication type:

Article

Genome-Wide Methylation Mapping Using Nanopore Sequencing Technology Identifies Novel Tumor Suppressor Genes in Hepatocellular Carcinoma.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 8, p. 3937, doi. 10.3390/ijms22083937

By:

Davenport, Colin F.;
Scheithauer, Tobias;
Dunst, Alessia;
Bahr, Frauke Sophie;
Dorda, Marie;
Wiehlmann, Lutz;
Tran, Doan Duy Hai

Publication type:

Article

Mapping in silico genetic networks of the KMT2D tumour suppressor gene to uncover novel functional associations and cancer cell vulnerabilities.

Published in:

Genome Medicine, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13073-024-01401-9

By:

Takemon, Yuka;
Pleasance, Erin D.;
Gagliardi, Alessia;
Hughes, Christopher S.;
Csizmok, Veronika;
Wee, Kathleen;
Trinh, Diane L.;
Huff, Ryan D.;
Mungall, Andrew J.;
Moore, Richard A.;
Chuah, Eric;
Mungall, Karen L.;
Lewis, Eleanor;
Nelson, Jessica;
Lim, Howard J.;
Renouf, Daniel J.;
Jones, Steven JM.;
Laskin, Janessa;
Marra, Marco A.

Publication type:

Article

Two single nucleotide polymorphisms in the von Hippel-Lindau tumor suppressor gene in Taiwanese with renal cell carcinoma.

Published in:

BMC Research Notes, 2014, v. 7, p. 1, doi. 10.1186/1756-0500-7-638

By:

Wen-Chung Wang;
Mei-Hua Tsou;
Hui-Ju Chen;
Wei-Fang Hsu;
Yen-Chein Lai

Publication type:

Article

Protein tyrosine phosphatases receptor type D is a potential tumour suppressor gene inactivated by deoxyribonucleic acid methylation in paediatric acute myeloid leukaemia.

Published in:

2016

By:

Song, Lei;
Jiang, Wen;
Liu, Wei;
Ji, Ju ‐ Hua;
Shi, Tai ‐ Feng;
Zhang, Jie;
Xia, Chun ‐ Qiu

Publication type:

journal article

Intellectual disability, oncogenes and tumour suppressor genes: the way forward?

Published in:

Journal of Genetics, 2012, v. 91, n. 2, p. 257, doi. 10.1007/s12041-012-0154-6

By:

BIDART, M.;
COUTTON, C.

Publication type:

Article

Tumor suppressor genes and their underlying interactions in paclitaxel resistance in cancer therapy.

Published in:

Cancer Cell International, 2016, v. 16, p. 1, doi. 10.1186/s12935-016-0290-9

By:

Jia-Hui Xu;
Shi-Lian Hu;
Guo-Dong Shen;
Gan Shen

Publication type:

Article

ASSOCIATION OF TUMOR SUPPRESSOR GENE CHEK2 1100DELC MUTATION WITH BREAST CANCER IN IRAQI WOMEN.

Published in:

Biochemical & Cellular Archives, 2019, v. 19, p. 2111, doi. 10.35124/bca.2019.19.S1.2111

By:

Sadeq, AL-Shimaysawee;
Hussein, Ghufran Mohammed;
AL-Shimaysawee, Ola Sadeq

Publication type:

Article

Abnormal promoter methylation of multiple tumor suppressor genes in human bronchial epithelial malignant cells.

Published in:

Biomedical Reports, 2014, v. 2, n. 4, p. 525, doi. 10.3892/br.2014.268

By:

CHAOYANG LIU;
PENG LI;
DEWEI GAO;
PINGKUN ZHOU;
YUN SHAO;
QI ZHANG;
WENBING LI

Publication type:

Article

Identification of homozygous deletions of tumor suppressor gene FAT in oral cancer using CGH-array.

Published in:

Oncogene, 2007, v. 26, n. 36, p. 5300, doi. 10.1038/sj.onc.1210330

By:

Nakaya, K.;
Yamagata, H. D.;
Arita, N.;
Nakashiro, K.-i.;
Nose, M.;
Miki, T.;
Hamakawa, H.

Publication type:

Article

RPS6KA2, a putative tumour suppressor gene at 6q27 in sporadic epithelial ovarian cancer.

Published in:

Oncogene, 2007, v. 26, n. 5, p. 683, doi. 10.1038/sj.onc.1209827

By:

Bignone, P. A.;
Lee, K. Y.;
Liu, Y.;
Emilion, G.;
Finch, J.;
Soosay, A. E. R.;
Charnock, F. M. L.;
Beck, S.;
Dunham, I.;
Mungall, A. J.;
Ganesan, T. S.

Publication type:

Article

E2F–HDAC complexes negatively regulate the tumor suppressor gene ARHI in breast cancer.

Published in:

Oncogene, 2006, v. 25, n. 2, p. 230, doi. 10.1038/sj.onc.1209025

By:

Lu, Z.;
Luo, R. Z.;
Peng, H.;
Huang, M.;
Nishmoto, A.;
Hunt, K. K.;
Helin, K.;
Liao, W. S.-L.;
Yu, Y.

Publication type:

Article

Promoter hypermethylation of tumour suppressor genes ( p14/ARF and p16/INK4a): case-control study in North Indian population.

Published in:

Molecular Biology Reports, 2013, v. 40, n. 8, p. 4921, doi. 10.1007/s11033-013-2592-5

By:

Askari, Marjan;
Sobti, Ranbir;
Nikbakht, Mohsen;
Sharma, Suresh

Publication type:

Article

Epigenetic analysis of FHL1 tumor suppressor gene in human liver cancer.

Published in:

Oncology Letters, 2017, v. 14, n. 5, p. 6109, doi. 10.3892/ol.2017.6950

By:

JUN WANG;
FANG HUANG;
JIAN HUANG;
JINDAN KONG;
SHENGLAN LIU;
JUN JIN

Publication type:

Article

Promoter methylation status of the tumor suppressor genes p16 and cadherin 1 in cervical intraepithelial neoplasia.

Published in:

Oncology Letters, 2017, v. 13, n. 6, p. 4397, doi. 10.3892/ol.2017.5975

By:

RUEI-NIAN LI;
CHIEN-YU LI;
CHIEN-HUNG LEE;
CHIUNG-YU PENG;
MING-TSANG WU

Publication type:

Article

CpG Island Hypermethylation of Tumor-Suppressor Genes in H. pylori-Infected Non-Neoplastic Gastric Mucosa Is Linked with Gastric Cancer Risk.

Published in:

Helicobacter, 2008, v. 13, n. 1, p. 35, doi. 10.1111/j.1523-5378.2008.00572.x

By:

Kaise, Mitsuru;
Yamasaki, Takuji;
Yonezawa, Jin;
Miwa, Jun;
Ohta, Yasuhiko;
Tajiri, Hisao

Publication type:

Article

Therapeutic Strategies Targeting Tumor Suppressor Genes in Pancreatic Cancer.

Published in:

Cancers, 2021, v. 13, n. 15, p. 3920, doi. 10.3390/cancers13153920

By:

Kuo, Kung-Kai;
Hsiao, Pi-Jung;
Chang, Wen-Tsan;
Chuang, Shih-Chang;
Yang, Ya-Han;
Wuputra, Kenly;
Ku, Chia-Chen;
Pan, Jia-Bin;
Li, Chia-Pei;
Kato, Kohsuke;
Liu, Chung-Jung;
Wu, Deng-Chyang;
Yokoyama, Kazunari K.

Publication type:

Article

Tumour suppressor genes in chemotherapeutic drug response.

Published in:

Bioscience Reports, 2012, v. 32, n. 4, p. 361, doi. 10.1042/BSR20110125

By:

LAI, Dulcie;
VISSER-GRIEVE, Stacy;
YANG, Xiaolong

Publication type:

Article

The candidate tumor suppressor gene Ecrg4 as a wound terminating factor in cutaneous injury.

Published in:

Archives of Dermatological Research, 2013, v. 305, n. 2, p. 141, doi. 10.1007/s00403-012-1276-7

By:

Shaterian, Ashkaun;
Kao, Steven;
Chen, Lin;
DiPietro, Luisa;
Coimbra, Raul;
Eliceiri, Brian;
Baird, Andrew

Publication type:

Article

Reclassification of variants of tumor suppressor genes based on Sanger RNA sequencing without NMD inhibition.

Published in:

Frontiers in Genetics, 2023, p. 1, doi. 10.3389/fgene.2023.1283611

By:

Changhee Ha;
Ja-Hyun Jang;
Young-gon Kim;
Jong-Won Kim

Publication type:

Article

Silencing of the tumor suppressor gene FHIT is highly characteristic for MLL gene rearranged infant acute lymphoblastic leukemia.

Published in:

2006

By:

Stam, R. W.;
den Boer, M. L.;
Passier, M. M. C. J.;
Janka-Schaub, G. E.;
Sallan, S. E.;
Armstrong, S. A.;
Pieters, R.

Publication type:

journal article

ING1 and ING2: multifaceted tumor suppressor genes.

Published in:

Cellular & Molecular Life Sciences, 2013, v. 70, n. 20, p. 3753, doi. 10.1007/s00018-013-1270-z

By:

Guérillon, Claire;
Larrieu, Delphine;
Pedeux, Rémy

Publication type:

Article

Electrochemical Determination of the p53 Tumor Suppressor Gene Using a Gold Nanoparticle-Graphene Nanocomposite Modified Glassy Carbon Electrode.

Published in:

Analytical Letters, 2017, v. 50, n. 2, p. 336, doi. 10.1080/00032719.2016.1178273

By:

Feng, Rongrong;
Hu, Xiaoqin;
He, Caimei;
Li, Xiaoxia;
Luo, Xianwen

Publication type:

Article

BTG2 is a tumor suppressor gene upregulated by p53 and PTEN in human bladder carcinoma cells.

Published in:

Cancer Medicine, 2018, v. 7, n. 1, p. 184, doi. 10.1002/cam4.1263

By:

Ke-Hung Tsui;
Kun-Chun Chiang;
Yu-Hsiang Lin;
Kang-Shuo Chang;
Tsui-Hsia Feng;
Horng-Heng Juang

Publication type:

Article

Integrative Genomic and Transcriptomic Analyses of Tumor Suppressor Genes and Their Role on Tumor Microenvironment and Immunity in Lung Squamous Cell Carcinoma.

Published in:

Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.598671

By:

Kim, Ahreum;
Lim, Sun Min;
Kim, Joo-Hang;
Seo, Jeong-Sun

Publication type:

Article

The SFRP family of WNT inhibitors function as novel tumor suppressor genes epigenetically silenced in medulloblastoma.

Published in:

Oncogene, 2010, v. 29, n. 20, p. 3017, doi. 10.1038/onc.2010.32

By:

Kongkham, P. N.;
Northcott, P. A.;
Croul, S. E.;
Smith, C. A.;
Taylor, M. D.;
Rutka, J. T.

Publication type:

Article

Impaired recruitment of the histone methyltransferase DOT1L contributes to the incomplete reactivation of tumor suppressor genes upon DNA demethylation.

Published in:

Oncogene, 2009, v. 28, n. 47, p. 4212, doi. 10.1038/onc.2009.267

By:

Jacinto, F. V.;
Ballestar, E.;
Esteller, M.

Publication type:

Article

Unmasking of epigenetically silenced candidate tumor suppressor genes by removal of methyl-CpG-binding domain proteins.

Published in:

Oncogene, 2008, v. 27, n. 25, p. 3556, doi. 10.1038/sj.onc.1211022

By:

Lopez-Serra, L.;
Ballestar, E.;
Ropero, S.;
Setien, F.;
Billard, L.-M.;
Fraga, M. F.;
Lopez-Nieva, P.;
Alaminos, M.;
Guerrero, D.;
Dante, R.;
Esteller, M.

Publication type:

Article

EZH2-Induced H3K27me3 is Associated with Epigenetic Repression of the ARHI Tumor-Suppressor Gene in Ovarian Cancer.

Published in:

Cell Biochemistry & Biophysics, 2015, v. 71, n. 1, p. 105, doi. 10.1007/s12013-014-0168-1

By:

Fu, Yibing;
Chen, Jing;
Pang, Bo;
Li, Chunyan;
Zhao, Jing;
Shen, Keng

Publication type:

Article

Constitutional Haploinsufficiency of Tumor Suppressor Genes in Mentally Retarded Patients With Microdeletions in 17p13.1.

Published in:

Cytogenetic & Genome Research, 2009, v. 125, n. 1, p. 1, doi. 10.1159/000218743

By:

Krepischi-Santos, A. C. V.;
Rajan, D.;
Temple, I. K.;
Shrubb, V.;
Crolla, J. A.;
Huang, S.;
Beal, S.;
Otto, P. A.;
Carter, N. P.;
Vianna-Morgante, A. M.;
Rosenberg, C.

Publication type:

Article

EGFR-mutant lung adenocarcinoma harboring co-mutational tumor suppressor genes predicts poor prognosis.

Published in:

Journal of Cancer Research & Clinical Oncology, 2020, v. 146, n. 7, p. 1781, doi. 10.1007/s00432-020-03237-3

By:

Zhao, Yue;
Pan, Yunjian;
Cheng, Chao;
Zheng, Difan;
Zhang, Yang;
Gao, Zhendong;
Fu, Fangqiu;
Li, Hang;
Zheng, Shanbo;
Zhuge, Lingdun;
Mao, Hengyu;
Kuang, Muyu;
Tao, Xiaoting;
Peng, Yizhou;
Hu, Hong;
Xiang, Jiaqing;
Li, Yuan;
Sun, Yihua;
Chen, Haiquan

Publication type:

Article

Indications for a tumor suppressor gene at 22q11 involved in the pathogenesis of ependymal tumors and distinct from hSNF5/INI1.

Published in:

Acta Neuropathologica, 2001, v. 102, n. 1, p. 69, doi. 10.1007/s004010000353

By:

Kraus, Jürgen A.;
de Millas, Walter;
Sörensen, Nils;
Herbold, Christian;
Schichor, Christian;
Tonn, Jörg C.;
Wiestler, Otmar D.;
von Deimling, Andreas;
Pietsch, Torsten

Publication type:

Article

The Role of Epstein-Barr Virus in Modulating Key Tumor Suppressor Genes in Associated Malignancies: Epigenetics, Transcriptional, and Post-Translational Modifications.

Published in:

Biomolecules (2218-273X), 2022, v. 12, n. 1, p. 127, doi. 10.3390/biom12010127

By:

Fierti, Adelaide Ohui;
Yakass, Michael Bright;
Okertchiri, Ernest Adjei;
Adadey, Samuel Mawuli;
Quaye, Osbourne

Publication type:

Article

Human medulloblastomas lack point mutations and homozygous deletions of the hSNF5/INI1 tumour suppressor gene.

Published in:

Neuropathology & Applied Neurobiology, 2002, v. 28, n. 2, p. 136, doi. 10.1046/j.1365-2990.2002.00388.x

By:

Kraus, J. A;
Oster, C;
Sörensen, N;
Berthold, F;
Schlegel, U;
Tonn, J. C;
Wiestler, O. D;
Pietsch, T

Publication type:

Article

Refined mapping of the region of loss of heterozygosity on the long arm of chromosome 7 in human breast cancer defines the location of a second tumor suppressor gene at 7q22 in the region of the CUTL1 gene.

Published in:

Oncogene, 1999, v. 18, n. 11, p. 2015, doi. 10.1038/sj.onc.1202519

By:

Zeng, Wendy Rong;
Watson, Peter;
Lin, Jenny;
Jothy, Serge;
Lidereau, Rosette;
Park, Morag;
Nepveu, Alain

Publication type:

Article

Cloning of two candidate tumor suppressor genes within a 10 kb region on chromosome 13q14, frequently deleted in chronic lymphocytic leukemia.

Published in:

Oncogene, 1997, v. 15, n. 20, p. 2463, doi. 10.1038/sj.onc.1201643

By:

Liu, Yie;
Corcoran, Martin;
Rasool, Omid;
Ivanova, Ganka;
Ibbotson, Rachel;
Grandér, Dan;
Iyengar, Arati;
Baranova, Anna;
Kashuba, Vladimir;
Merup, Mats;
Wu, Xiushan;
Gardiner, Anne;
Mullenbach, Roman;
Poltaraus, Andrew;
Hultström, Anna Linda;
Juliusson, Gunnar;
Chapman, Robert;
Tiller, Mary;
Cotter, Finbarr;
Gahrton, Gösta

Publication type:

Article

Loss of Mitochondrial Tumor Suppressor Genes Expression Is Associated with Unfavorable Clinical Outcome in Head and Neck Squamous Cell Carcinoma: Data from Retrospective Study.

Published in:

PLoS ONE, 2016, v. 11, n. 1, p. 1, doi. 10.1371/journal.pone.0146948

By:

Mahjabeen, Ishrat;
Kayani, Mahmood Akhtar

Publication type:

Article

Haploinsufficiency of Tumor Suppressor Genes is Driven by the Cumulative Effect of microRNAs, microRNA Binding Site Polymorphisms and microRNA Polymorphisms: An In silico Approach.

Published in:

Cancer Informatics, 2012, n. 11, p. 157, doi. 10.4137/CIN.S10176

By:

Manikandan, Mayakannan;
Raksha, Ganesh;
Kannan Munirajan, Arasambattu

Publication type:

Article

Redefining tumour suppressor genes: exceptions to the two-hit hypothesis.

Published in:

Cellular & Molecular Life Sciences, 2003, v. 60, n. 10, p. 2147, doi. 10.1007/s00018-003-3027-6

By:

Paige, A. J. W.

Publication type:

Article

Tumor suppressor genes in oral cancer.

Published in:

Clinical Cancer Investigation Journal, 2015, v. 4, n. 6, p. 697, doi. 10.4103/2278-0513.165753

By:

Naik, Vinayak Gourish;
Adhyaru, Prakruti;
Gudigenavar, Ajit

Publication type:

Article

Tumor suppressor genes in ovarian cancer: the relationship with grade and stage.

Published in:

International Journal of Health Science, 2008, v. 1, n. 2, p. 37

By:

D'Andrilli, Giuseppina;
Giordano, Antonio;
Bovicelli, Alessandro

Publication type:

Article

Tumour suppressor gene mutations in humans and mice: parallels and contrasts.

Published in:

EMBO Journal, 1998, v. 17, n. 23, p. 6783, doi. 10.1093/emboj/17.23.6783

By:

Hooper, Martin L.

Publication type:

Article

Oxidation Chemistry of DNA and p53 Tumor Suppressor Gene.

Published in:

ChemistryOpen, 2019, v. 8, n. 3, p. 252, doi. 10.1002/open.201800292

By:

Jiang, Di;
Rusling, James F.

Publication type:

Article

Modulation of Estrogen Receptor Alpha (ERα) and Tumor Suppressor Gene BRCA1 in Breast Cancer Cells by Bazedoxifene Acetate (BZA).

Published in:

Cancers, 2024, v. 16, n. 4, p. 699, doi. 10.3390/cancers16040699

By:

Szmyd, Monica;
Zanib, Aisha;
Behlow, Victoria;
Hallman, Erin;
Pfiffner, Samantha;
Yaldo, Raquel;
Prudhomme, Nina;
Farrar, Katelyn;
Dinda, Sumi

Publication type:

Article