Title: Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis.
Authors: Niu, Guilian; Wright, Kenneth L.; Huang, Mei; Song, Lanxi; Haura, Eric; Turkson, James; Shumin Zhang; Wang, Tianhong; Sinibaldi, Dominic; Coppola, Domenico; Heller, Richard; Ellis, Lee M.; Karras, James; Bromberg, Jacqueline; Pardoll, Drew; Jove, Richard; Hua Yu
Abstract: Presents a study that examined the correlation between vascular endothelial growth factor (VEGF) and signal transducer and activator of transcription 3 activity in human diverse cancer cell lines. List of receptor tyrosine kinases; Importance of angiogenesis in tumors; Descriptions on VEGF; Factors affecting the induction of VEGF and tumor angiogenesis.
Subjects: GROWTH factors; VASCULAR endothelium; PROTEIN-tyrosine kinases; NEOVASCULARIZATION
Publication: Oncogene, 2002, Vol 21, Issue 13, p2000
ISSN: 0950-9232
Publication type: Academic Journal
DOI: 10.1038/sj.onc.1205260

Constitutive Stat3 activity up-regulates VEGF expression and tumor angiogenesis.

Niu, Guilian; Wright, Kenneth L.; Huang, Mei; Song, Lanxi; Haura, Eric; Turkson, James; Shumin Zhang; Wang, Tianhong; Sinibaldi, Dominic; Coppola, Domenico; Heller, Richard; Ellis, Lee M.; Karras, James; Bromberg, Jacqueline; Pardoll, Drew; Jove, Richard; Hua Yu