Works matching THC receptors

Results: 131

CB1 Receptor Antagonist Selonabant (ANEB‐001) Blocks Acute THC Effects in Healthy Volunteers: A Phase II Randomized Controlled Trial.

Published in:

Clinical Pharmacology & Therapeutics, 2025, v. 117, n. 5, p. 1427, doi. 10.1002/cpt.3581

By:

Gorbenko, Andriy A.;
Heuberger, Jules A. A. C.;
Juachon, Maria;
Klaassen, Erica;
Tagen, Michael;
Lawler, Joseph F.;
Schneeberger, Daniel;
Cundy, Kenneth C.;
Klumpers, Linda E.;
Groeneveld, Geert J.

Publication type:

Article

The Cannabinoid Receptor CB1 Interacts with the WAVE1 Complex and Plays a Role in Actin Dynamics and Structural Plasticity in Neurons.

Published in:

PLoS Biology, 2015, v. 13, n. 10, p. 1, doi. 10.1371/journal.pbio.1002286

By:

Njoo, Christian;
Agarwal, Nitin;
Lutz, Beat;
Kuner, Rohini

Publication type:

Article

Selective Reduction of THC’s Unwanted Effects through Serotonin Receptor Inhibition.

Published in:

PLoS Biology, 2015, v. 13, n. 7, p. 1, doi. 10.1371/journal.pbio.1002193

By:

Robinson, Richard

Publication type:

Article

The cannabinoid CB receptor is necessary for nicotine-conditioned place preference, but not other behavioral effects of nicotine in mice.

Published in:

Psychopharmacology, 2013, v. 229, n. 4, p. 591, doi. 10.1007/s00213-013-3117-6

By:

Ignatowska-Jankowska, Bogna;
Muldoon, Pretal;
Lichtman, Aron;
Damaj, M.

Publication type:

Article

The Cannabinoid Receptor Agonist THC Attenuates Weight Loss in a Rodent Model of Activity-Based Anorexia.

Published in:

Neuropsychopharmacology, 2011, v. 36, n. 7, p. 1349, doi. 10.1038/npp.2011.19

By:

Verty, Aaron N. A.;
Evetts, Megan J.;
Crouch, Geraldine J.;
McGregor, Iain S.;
Stefanidis, Aneta;
Oldfield, Brian J.

Publication type:

Article

CB1 and CB2 Cannabinoid Receptors Mediate Different Aspects of Delta-9-Tetrahydrocannabinol (THC)-Induced T Helper Cell Shift Following Immune Activation by Legionella Pneumophila Infection.

Published in:

Journal of NeuroImmune Pharmacology, 2009, v. 4, n. 4, p. 92, doi. 10.1007/s11481-008-9126-2

By:

Newton, Catherine;
Chou, Ping-Jen;
Perkins, Izabella;
Klein, Thomas

Publication type:

Article

CB1 and CB2 Cannabinoid Receptors Mediate Different Aspects of Delta-9-Tetrahydrocannabinol (THC)-Induced T Helper Cell Shift Following Immune Activation by Legionella Pneumophila Infection.

Published in:

Journal of NeuroImmune Pharmacology, 2009, v. 4, n. 1, p. 92, doi. 10.1007/s11481-008-9126-2

By:

Newton, Catherine;
Chou, Ping-Jen;
Perkins, Izabella;
Klein, Thomas

Publication type:

Article

Differential Effects of Presynaptic versus Postsynaptic Adenosine A2A Receptor Blockade on Δ9-Tetrahydrocannabinol (THC) Self-Administration in Squirrel Monkeys.

Published in:

Journal of Neuroscience, 2014, v. 34, n. 19, p. 6480, doi. 10.1523/JNEUROSCI.5073-13.2014

By:

Justinova, Zuzaná;
Redhi, Godfrey H.;
Goldberg, Steven R.;
Ferré, Sergi

Publication type:

Article

Ligands that target cannabinoid receptors in the brain: from THC to anandamide and beyond.

Published in:

Addiction Biology, 2008, v. 13, n. 2, p. 147, doi. 10.1111/j.1369-1600.2008.00108.x

By:

Pertwee, Roger G.

Publication type:

Article

A PCR marker Linked to a THCA synthase Polymorphism is a Reliable Tool to Discriminate Potentially THC-Rich Plants of Cannabis sativa L.

Published in:

Journal of Forensic Sciences, 2014, v. 59, n. 4, p. 919, doi. 10.1111/1556-4029.12448

By:

Staginnus, Christina;
Zörntlein, Siegfried;
Meijer, Etienne

Publication type:

Article

Potential Pro-Inflammatory Effect of Vitamin E Analogs through Mitigation of Tetrahydrocannabinol (THC) Binding to the Cannabinoid 2 Receptor.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 8, p. 4291, doi. 10.3390/ijms23084291

By:

Manandhar, Anjela;
Haron, Mona H.;
Ross, Samir A.;
Klein, Michael L.;
Elokely, Khaled M.

Publication type:

Article

Cannabidiol Exerts Anticonvulsant Effects Alone and in Combination with Δ 9 -THC through the 5-HT1A Receptor in the Neocortex of Mice.

Published in:

Cells (2073-4409), 2024, v. 13, n. 6, p. 466, doi. 10.3390/cells13060466

By:

Javadzadeh, Yasaman;
Santos, Alexandra;
Aquilino, Mark S.;
Mylvaganam, Shanthini;
Urban, Karolina;
Carlen, Peter L.

Publication type:

Article

Neuronal nicotinic acetylcholine receptors mediate ∆9 -THC dependence: Mouse and human studies.

Published in:

2020

By:

Donvito, Giulia;
Muldoon, Pretal P.;
Jackson, Kia J.;
Ahmad, Urslan;
Zaveri, Nur T.;
McIntosh, J. Michael;
Chen, Xiangning;
Lichtman, Aron H.;
Damaj, M. Imad

Publication type:

journal article

Kanabidiol, kanabinoidy a jejich vliv na celkovou anestezii.

Published in:

Remedia, 2024, v. 34, n. 6, p. 480

By:

Hess, Ladislav

Publication type:

Article

Cannabidiol is an allosteric modulator at mu- and delta-opioid receptors.

Published in:

Naunyn-Schmiedeberg's Archives of Pharmacology, 2006, v. 372, n. 5, p. 354, doi. 10.1007/s00210-006-0033-x

By:

Kathmann, Markus;
Flau, Karsten;
Redmer, Agnes;
Tränkle, Christian;
Schlicker, Eberhard

Publication type:

Article

Motivational Effects of Cannabinoids and Opioids on Food Reinforcement Depend on Simultaneous Activation of Cannabinoid and Opioid Systems.

Published in:

Neuropsychopharmacology, 2005, v. 30, n. 11, p. 2035, doi. 10.1038/sj.npp.1300720

By:

Solinas, Marcello;
Goldberg, Steven R

Publication type:

Article

Role of vasopressin V1a receptor in ∆-tetrahydrocannabinol-induced cataleptic immobilization in mice.

Published in:

Psychopharmacology, 2017, v. 234, n. 23/24, p. 3475, doi. 10.1007/s00213-017-4735-1

By:

Egashira, Nobuaki;
Koushi, Emi;
Myose, Takayuki;
Tanoue, Akito;
Mishima, Kenichi;
Tsuchihashi, Ryota;
Kinjo, Junei;
Tanaka, Hiroyuki;
Morimoto, Satoshi;
Iwasaki, Katsunori

Publication type:

Article

The pharmacokinetics of THC in fat and brain: resulting functional responses to marihuana smoking.

Published in:

Human Psychopharmacology: Clinical & Experimental, 2001, v. 16, n. 3, p. 247, doi. 10.1002/hup.258

By:

Nahas, Gabriel G.

Publication type:

Article

Psychoactive cannabinoids and membrane signaling.

Published in:

Human Psychopharmacology: Clinical & Experimental, 2000, v. 15, n. 7, p. 535, doi. 10.1002/1099-1077(200010)15:7<535::AID-HUP229>3.0.CO;2-7

By:

Nahas, Gabriel G.;
Harvey, David J.;
Sutin, Kenneth M.

Publication type:

Article

Medium-throughput zebrafish optogenetic platform identifies deficits in subsequent neural activity following brief early exposure to cannabidiol and Δ9-tetrahydrocannabinol.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-90902-3

By:

Kanyo, Richard;
Amin, Md Ruhul;
Locskai, Laszlo F.;
Bouvier, Danika D.;
Olthuis, Alexandria M.;
Allison, W. Ted;
Ali, Declan W.

Publication type:

Article

FAAH−/− Mice Display Differential Tolerance, Dependence, and Cannabinoid Receptor Adaptation After Δ9-Tetrahydrocannabinol and Anandamide Administration.

Published in:

Neuropsychopharmacology, 2010, v. 35, n. 8, p. 1775, doi. 10.1038/npp.2010.44

By:

Falenski, Katherine W.;
Thorpe, Andrew J.;
Schlosburg, Joel E.;
Cravatt, Benjamin F.;
Abdullah, Rehab A.;
Smith, Tricia H.;
Selley, Dana E.;
Lichtman, Aron H.;
Sim-Selley, Laura J.

Publication type:

Article

Emergence of Synthetic Cannabinoids as Drugs of Abuse.

Published in:

Indian Journal of Forensic Medicine & Toxicology, 2022, v. 16, n. 1, p. 89, doi. 10.37506/ijfmt.v16i1.17422

By:

Joshi, Nupur;
Sankhla, Mahipal Singh

Publication type:

Article

Effect of tetrahydrocurcumin on insulin receptor status in type 2 diabetic rats: studies on insulin binding to erythrocytes.

Published in:

Journal of Biosciences, 2008, v. 33, n. 1, p. 63, doi. 10.1007/s12038-008-0022-y

By:

Murugan, Pidaran;
Pari, Leelavinothan;
Rao, Chippada Appa

Publication type:

Article

Suppression of STAT3 Signaling by Δ9-Tetrahydrocannabinol (THC) Induces Trophoblast Dysfunction.

Published in:

Cellular Physiology & Biochemistry (Karger AG), 2017, v. 42, n. 2, p. 537, doi. 10.1159/000477603

By:

Chang, Xinwen;
Bian, Yiding;
He, Qizhi;
Yao, Julei;
Zhu, Jingping;
Wu, Jinting;
Wang, Kai;
Duan, Tao

Publication type:

Article

Tetrahydrocannabinol and dopamine D1 receptor.

Published in:

Frontiers in Neuroscience, 2024, p. 1, doi. 10.3389/fnins.2024.1360205

By:

Lee, Jiwon

Publication type:

Article

Anti-inflammatory activity of topical THC in DNFB-mediated mouse allergic contact dermatitis independent of CB1 and CB2 receptors.

Published in:

Allergy, 2013, v. 68, n. 8, p. 994, doi. 10.1111/all.12183

By:

Gaffal, E.;
Cron, M.;
Glodde, N.;
Tüting, T.

Publication type:

Article

The effects of Delta9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide.

Published in:

2005

By:

O'Sullivan, Saoirse E;
Kendall, David A;
Randall, Michael D

Publication type:

journal article

The effects of Δ9-tetrahydrocannabinol in rat mesenteric vasculature, and its interactions with the endocannabinoid anandamide.

Published in:

British Journal of Pharmacology, 2005, v. 145, n. 4, p. 514, doi. 10.1038/sj.bjp.0706218

By:

O'Sullivan, Saoirse E.;
Kendall, David A.;
Randall, Michael D.

Publication type:

Article

THC-induced behavioral stereotypy in zebrafish as a model of psychosis-like behavior.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-95016-4

By:

Dahlén, Amelia;
Zarei, Mahdi;
Melgoza, Adam;
Wagle, Mahendra;
Guo, Su

Publication type:

Article

Administration of Δ9‐Tetrahydrocannabinol (THC) Post‐Staphylococcal Enterotoxin B Exposure Protects Mice From Acute Respiratory Distress Syndrome and Toxicity.

Published in:

Frontiers in Pharmacology, 2020, v. 11, p. 1, doi. 10.3389/fphar.2020.00893

By:

Mohammed, Amira;
Alghetaa, Hasan;
Sultan, Muthanna;
Singh, Narendra P.;
Nagarkatti, Prakash;
Nagarkatti, Mitzi

Publication type:

Article

Involvement of opioid system in cognitive deficits induced by ∆-tetrahydrocannabinol in rats.

Published in:

Psychopharmacology, 2012, v. 219, n. 4, p. 1111, doi. 10.1007/s00213-011-2442-x

By:

Egashira, Nobuaki;
Manome, Naomi;
Mishima, Kenichi;
Iwasaki, Katsunori;
Oishi, Ryozo;
Fujiwara, Michihiro

Publication type:

Article

Cannabidiol potentiates Δ-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats.

Published in:

Psychopharmacology, 2011, v. 218, n. 2, p. 443, doi. 10.1007/s00213-011-2342-0

By:

Klein, Charlotte;
Karanges, Emily;
Spiro, Adena;
Wong, Alexander;
Spencer, Jarrah;
Huynh, Thanh;
Gunasekaran, Nathan;
Karl, Tim;
Long, Leonora;
Huang, Xu-Feng;
Liu, Kelly;
Arnold, Jonathon;
McGregor, Iain

Publication type:

Article

Interactions between Δ9-tetrahydrocannabinol and μ opioid receptor agonists in rhesus monkeys: discrimination and antinociception.

Published in:

Psychopharmacology, 2008, v. 199, n. 2, p. 199, doi. 10.1007/s00213-008-1157-0

By:

Li, Jun-Xu;
McMahon, Lance;
Gerak, Lisa;
Becker, Ginger;
France, Charles

Publication type:

Article

A marine sponge-derived lectin reveals hidden pathway for thrombopoietin receptor activation.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-34921-2

By:

Watari, Hiromi;
Kageyama, Hiromu;
Masubuchi, Nami;
Nakajima, Hiroya;
Onodera, Kako;
Focia, Pamela J.;
Oshiro, Takumi;
Matsui, Takashi;
Kodera, Yoshio;
Ogawa, Tomohisa;
Yokoyama, Takeshi;
Hirayama, Makoto;
Hori, Kanji;
Freymann, Douglas M.;
Imai, Misa;
Komatsu, Norio;
Araki, Marito;
Tanaka, Yoshikazu;
Sakai, Ryuichi

Publication type:

Article

Down-regulation of the AMPA glutamate receptor subunits GluR1 and GluR2/3 in the rat cerebellum following pre- and perinatal Δ9-tetrahydrocannabinol exposure.

Published in:

Cerebellum, 2004, v. 3, n. 2, p. 66

By:

Suárez, Isabel;
Bodega, Guillermo;
Fermández-Ruitz, Javier;
Ramos, José Antonio;
Rubio, Miguel;
Fernandez, Benjamín

Publication type:

Article

Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors.

Published in:

PLoS Biology, 2015, v. 13, n. 7, p. 1, doi. 10.1371/journal.pbio.1002194

By:

Viñals, Xavier;
Moreno, Estefanía;
Lanfumey, Laurence;
Cordomí, Arnau;
Pastor, Antoni;
de La Torre, Rafael;
Gasperini, Paola;
Navarro, Gemma;
Howell, Lesley A.;
Pardo, Leonardo;
Lluís, Carmen;
Canela, Enric I.;
McCormick, Peter J.;
Maldonado, Rafael;
Robledo, Patricia

Publication type:

Article

Cellular Mechanisms Underlying the Anxiolytic Effect of Low Doses of Peripheral Δ9-Tetrahydrocannabinol in Rats.

Published in:

Neuropsychopharmacology, 2007, v. 32, n. 9, p. 2036, doi. 10.1038/sj.npp.1301330

By:

Rubino, Tiziana;
Sala, Mariaelvina;
Viganò, Daniela;
Braida, Daniela;
Castiglioni, Chiara;
Limonta, Valeria;
Guidali, Cinzia;
Realini, Natalia;
Parolaro, Daniela

Publication type:

Article

Cannabinoid Agonists but not Inhibitors of Endogenous Cannabinoid Transport or Metabolism Enhance the Reinforcing Efficacy of Heroin in Rats.

Published in:

Neuropsychopharmacology, 2005, v. 30, n. 11, p. 2046, doi. 10.1038/sj.npp.1300754

By:

Solinas, Marcello;
Panlilio, Leigh V.;
Tanda, Gianluigi;
Makriyannis, Alexandros;
Matthews, Stephanie A.;
Goldberg, Steven R.

Publication type:

Article

Neuronal and non-neuronal TRPA1 as therapeutic targets for pain and headache relief.

Published in:

Temperature, 2023, v. 10, n. 1, p. 50, doi. 10.1080/23328940.2022.2075218

By:

Iannone, Luigi F.;
Nassini, Romina;
Patacchini, Riccardo;
Geppetti, Pierangelo;
De Logu, Francesco

Publication type:

Article

Acute administration of THC impairs spatial but not associative memory function in zebrafish.

Published in:

Psychopharmacology, 2014, v. 231, n. 19, p. 3829, doi. 10.1007/s00213-014-3522-5

By:

Ruhl, Tim;
Prinz, Nicole;
Oellers, Nadine;
Seidel, Nathan;
Jonas, Annika;
Albayram, Önder;
Bilkei-Gorzo, Andras;
Emde, Gerhard

Publication type:

Article

A comparison of cannabidiolic acid with other treatments for anticipatory nausea using a rat model of contextually elicited conditioned gaping.

Published in:

Psychopharmacology, 2014, v. 231, n. 16, p. 3207, doi. 10.1007/s00213-014-3498-1

By:

Rock, Erin;
Limebeer, Cheryl;
Navaratnam, Roshan;
Sticht, Martin;
Bonner, Natasha;
Engeland, Kristin;
Downey, Rachel;
Morris, Heather;
Jackson, Meagan;
Parker, Linda

Publication type:

Article

Differentiation between low- and high-efficacy CB receptor agonists using a drug discrimination protocol for rats.

Published in:

Psychopharmacology, 2014, v. 231, n. 3, p. 489, doi. 10.1007/s00213-013-3257-8

By:

Järbe, Torbjörn;
LeMay, Brian;
Halikhedkar, Aneetha;
Wood, JodiAnne;
Vadivel, Subramanian;
Zvonok, Alexander;
Makriyannis, Alexandros

Publication type:

Article

THC Reduces Ki67-Immunoreactive Cells Derived from Human Primary Glioblastoma in a GPR55-Dependent Manner.

Published in:

Cancers, 2021, v. 13, n. 5, p. 1064, doi. 10.3390/cancers13051064

By:

Kolbe, Marc Richard;
Hohmann, Tim;
Hohmann, Urszula;
Ghadban, Chalid;
Mackie, Ken;
Zöller, Christin;
Prell, Julian;
Illert, Jörg;
Strauss, Christian;
Dehghani, Faramarz;
Falasca, Marco;
Maccarrone, Mauro;
McMullin, Mary Frances

Publication type:

Article

THC and sperm: Impact on fertilization capability, pre-implantation in vitro development and epigenetic modifications.

Published in:

PLoS ONE, 2024, v. 19, n. 3, p. 1, doi. 10.1371/journal.pone.0298697

By:

Kuzma-Hunt, Alexander G.;
Sabry, Reem;
Davis, Ola S.;
Truong, Vivien B.;
Khokhar, Jibran Y.;
Favetta, Laura A.

Publication type:

Article

Up in Smoke: The Impacts of Marijuana During Pregnancy.

Published in:

Neonatal Network, 2023, v. 42, n. 4, p. 222, doi. 10.1891/NN-2022-0040

By:

McPherson, Christopher

Publication type:

Article

Cannabidiol and Tetrahydrocannabinol Antinociceptive Activity is Mediated by Distinct Receptors in Caenorhabditis elegans.

Published in:

Neurochemical Research, 2024, v. 49, n. 4, p. 935, doi. 10.1007/s11064-023-04069-6

By:

Boujenoui, Fatma;
Nkambeu, Bruno;
Salem, Jennifer Ben;
Castano Uruena, Jesus David;
Beaudry, Francis

Publication type:

Article

Systemic, but not local, administration of cannabinoid CB1 receptor agonists modulate prefrontal cortical acetylcholine efflux in the rat.

Published in:

Synapse, 2003, v. 48, n. 4, p. 178, doi. 10.1002/syn.10202

By:

Christopher D. Verrico;
J. David Jentsch;
Laura Dazzi

Publication type:

Article

An Individuality of Response to Cannabinoids: Challenges in Safety and Efficacy of Cannabis Products.

Published in:

Molecules, 2023, v. 28, n. 6, p. 2791, doi. 10.3390/molecules28062791

By:

Kitdumrongthum, Sarunya;
Trachootham, Dunyaporn

Publication type:

Article

Cannabis-Derived Compounds Cannabichromene and Δ9-Tetrahydrocannabinol Interact and Exhibit Cytotoxic Activity against Urothelial Cell Carcinoma Correlated with Inhibition of Cell Migration and Cytoskeleton Organization.

Published in:

Molecules, 2021, v. 26, n. 2, p. 465, doi. 10.3390/molecules26020465

By:

Anis, Omer;
Vinayaka, Ajjampura C.;
Shalev, Nurit;
Namdar, Dvora;
Nadarajan, Stalin;
Anil, Seegehalli M.;
Cohen, Ofer;
Belausov, Eduard;
Ramon, Jacob;
Mayzlish Gati, Einav;
Koltai, Hinanit;
Calapai, Gioacchino

Publication type:

Article

CB1 and CB2 Receptor Expression and Promoter Methylation in Patients with Cannabis Dependence.

Published in:

European Addiction Research, 2012, v. 19, n. 1, p. 13, doi. 10.1159/000338642

By:

Rotter, Andrea;
Bayerlein, Kristina;
Hansbauer, Max;
Weiland, Judith;
Sperling, Wolfgang;
Kornhuber, Johannes;
Biermann, Teresa

Publication type:

Article