Works matching DE "DISCOIDIN domain receptor 1"

Results: 86

Interleukin-1β mediates a tumor-supporting environment prompted by IGF1 in triple-negative breast cancer (TNBC).

Published in:

Journal of Translational Medicine, 2025, v. 23, n. 1, p. 1, doi. 10.1186/s12967-025-06730-w

By:

Scordamaglia, Domenica;
Talia, Marianna;
Cirillo, Francesca;
Zicarelli, Azzurra;
Mondino, Adelina Assunta;
De Rosis, Salvatore;
Di Dio, Marika;
Silvestri, Francesca;
Meliti, Chiara;
Miglietta, Anna Maria;
Capalbo, Carlo;
De Francesco, Ernestina Marianna;
Belfiore, Antonino;
Maggiolini, Marcello;
Lappano, Rosamaria

Publication type:

Article

Loss-of-function of DDR1 is responsible for a chondrodysplasia with multiple dislocations.

Published in:

Journal of Bone & Mineral Research, 2025, v. 40, n. 3, p. 362, doi. 10.1093/jbmr/zjae205

By:

Villegas Villarroel, Miriam;
Huber, Céline;
Baujat, Geneviève;
Bonnard, Adeline;
Collet, Corinne;
Cormier-Daire, Valérie

Publication type:

Article

DDR1 is identified as an immunotherapy target for microsatellite stable colon cancer by CRISPR screening.

Published in:

NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00743-2

By:

Wu, Miaoqing;
Ma, Wenjuan;
Lv, Guangzhao;
Wang, Xin;
Li, Cong;
Chen, Xiang;
Peng, Xiaofei;
Tang, Chaoming;
Pan, Zhizhong;
Liu, Ranyi;
Chen, Gong;
Zhang, Rongxin

Publication type:

Article

The role of discoid domain receptor 1 on renal tubular epithelial pyroptosis in diabetic nephropathy.

Published in:

Korean Journal of Physiology & Pharmacology, 2022, v. 26, n. 6, p. 427, doi. 10.4196/kjpp.2022.26.6.427

By:

Weichen Zhao;
Chunyuan He;
Junjie Jiang;
Zongbiao Zhao;
Hongzhong Yuan;
Facai Wang;
Bingxiang Shen

Publication type:

Article

Prognostic significance of TM4SF1 and DDR1 expression in epithelial ovarian cancer.

Published in:

Oncology Letters, 2023, v. 26, n. 4, p. N.PAG, doi. 10.3892/ol.2023.14035

By:

Huang, Zhijiong;
Yao, Hongyu;
Yang, Zhijun

Publication type:

Article

miR‑199b‑5p inhibits triple negative breast cancer cell proliferation, migration and invasion by targeting DDR1.

Published in:

Oncology Letters, 2018, v. 16, n. 4, p. 4889, doi. 10.3892/ol.2018.9255

By:

Wu, Anhao;
Chen, Yan;
Liu, Yang;
Lai, Yafang;
Liu, Dequan

Publication type:

Article

Discoidin domain receptor 1: New star in cancer-targeted therapy and its complex role in breast carcinoma (Review).

Published in:

Oncology Letters, 2018, v. 15, n. 3, p. 3403, doi. 10.3892/ol.2018.7795

By:

Jing, Hui;
Song, Jingyuan;
ZhENg, Junnian

Publication type:

Article

Antitumor activity of 7RH, a discoidin domain receptor 1 inhibitor, alone or in combination with dasatinib exhibits antitumor effects in nasopharyngeal carcinoma cells.

Published in:

Oncology Letters, 2016, v. 12, n. 5, p. 3598, doi. 10.3892/ol.2016.5088

By:

QIU-PING LU;
WEN-DAN CHEN;
JIE-REN PENG;
YAO-DONG XU;
QIAN-CA;
GONG-KAN FENG;
KE DING;
XIAO-FENG ZHU;
ZHONG GUAN

Publication type:

Article

Promotion of miR-221-5p on the Sensitivity of Gastric Cancer Cells to Cisplatin and Its Effects on Cell Proliferation and Apoptosis by Regulating DDR1 [Retraction].

Published in:

2021

By:

Jiang, Xiaomeng;
Jiang, Menglin;
Guo, Shuhua;
Cai, Pengpeng;
Wang, Wei;
Li, Yi

Publication type:

Correction Notice

Promotion of miR-221-5p on the Sensitivity of Gastric Cancer Cells to Cisplatin and Its Effects on Cell Proliferation and Apoptosis by Regulating DDR1.

Published in:

OncoTargets & Therapy, 2020, v. 13, p. 2333, doi. 10.2147/OTT.S232953

By:

Jiang, Xiaomeng;
Jiang, Menglin;
Guo, Shuhua;
Cai, Pengpeng;
Wang, Wei;
Li, Yi

Publication type:

Article

Deficiency in DDR1 Induces Pulmonary Hypertension and Impaired Alveolar Development.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2022, v. 67, n. 5, p. 562, doi. 10.1165/rcmb.2022-0124OC

By:

Bonafiglia, Quinn A.;
Yu-Qing Zhou;
Guangpei Hou;
Saha, Rhidita;
Hsu, Ying-Han R.;
Burke-Kleinman, Jonah;
Bendeck, Michelle P.

Publication type:

Article

DDR1 Deficiency in Mice: A Spontaneous Model of Bronchopulmonary Dysplasia-associated Pulmonary Hypertension?

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2022, v. 67, n. 5, p. 518, doi. 10.1165/rcmb.2022-0312ed

By:

Çataltepe, Sule;
Cox, Laura A.

Publication type:

Article

Identification of DDR1 Inhibitors from Marine Compound Library Based on Pharmacophore Model and Scaffold Hopping.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 3, p. 1099, doi. 10.3390/ijms26031099

By:

Hu, Honghui;
Tao, Jiahua;
Luo, Lianxiang

Publication type:

Article

Mutational analysis of the tyrosine kinome in serous and clear cell endometrial cancer uncovers rare somatic mutations in TNK2 and DDR1.

Published in:

BMC Cancer, 2014, v. 14, n. 1, p. 1, doi. 10.1186/1471-2407-14-884

By:

Rudd, Meghan L.;
Mohamed, Hassan;
Price, Jessica C.;
O'Hara, Andrea J.;
Le Gallo, Matthieu;
Urick, Mary Ellen;
Cruz, Pedro;
Suiyuan Zhang;
Hansen, Nancy F.;
Godwin, Andrew K.;
Sgroi, Dennis C.;
Wolfsberg, Tyra G.;
Mullikin, James C.;
Merino, Maria J.;
Bell, Daphne W.

Publication type:

Article

Mutational analysis of the tyrosine kinome in serous and clear cell endometrial cancer uncovers rare somatic mutations in TNK2 and DDR1.

Published in:

BMC Cancer, 2014, v. 14, p. 1, doi. 10.1186/1471-2407-14-884

By:

Rudd, Meghan L.;
Mohamed, Hassan;
Price, Jessica C.;
O'Hara, Andrea J.;
Le Gallo, Matthieu;
Urick, Mary Ellen;
Cruz, Pedro;
Zhang, Suiyuan;
Hansen, Nancy F.;
Godwin, Andrew K.;
Sgroi, Dennis C.;
Wolfsberg, Tyra G.;
Mullikin, James C.;
Merino, Maria J.;
Bell, Daphne W.

Publication type:

Article

HNRNPC promotes collagen fiber alignment and immune evasion in breast cancer via activation of the VIRMA-mediated TFAP2A/DDR1 axis.

Published in:

Molecular Medicine, 2023, v. 29, n. 1, p. 1, doi. 10.1186/s10020-023-00696-5

By:

Lian, Bin;
Yan, Shuxun;
Li, Jiayi;
Bai, Zhengyang;
Li, Jinping

Publication type:

Article

Curcumin derivative ST09 modulates the miR-199a-5p/DDR1 axis and regulates proliferation and migration in ovarian cancer cells.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-02454-1

By:

Ravindran, Febina;
Koroth, Jinsha;
Manjunath, Meghana;
Narayan, Suchitra;
Choudhary, Bibha

Publication type:

Article

MRIP Regulates the Myosin IIA Activity and DDR1 Function to Enable Collagen Tractional Remodeling.

Published in:

Cells (2073-4409), 2020, v. 9, n. 7, p. 1672, doi. 10.3390/cells9071672

By:

Coelho, Nuno M.;
Wang, Andrew;
Petrovic, Petar;
Wang, Yongqiang;
Lee, Wilson;
McCulloch, Christopher A.

Publication type:

Article

Breast tissue regeneration is driven by cell-matrix interactions coordinating multi-lineage stem cell differentiation through DDR1.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27401-6

By:

Rauner, Gat;
Jin, Dexter X.;
Miller, Daniel H.;
Gierahn, Todd M.;
Li, Carman M.;
Sokol, Ethan S.;
Feng, Yu-Xiong;
Mathis, Robert A.;
Love, J. Christopher;
Gupta, Piyush B.;
Kuperwasser, Charlotte

Publication type:

Article

A Membrane-Type-1 Matrix Metalloproteinase (MT1-MMP) – Discoidin Domain Receptor 1 Axis Regulates Collagen-Induced Apoptosis in Breast Cancer Cells.

Published in:

PLoS ONE, 2015, v. 10, n. 3, p. 1, doi. 10.1371/journal.pone.0116006

By:

Assent, Delphine;
Bourgot, Isabelle;
Hennuy, Benoît;
Geurts, Pierre;
Noël, Agnès;
Foidart, Jean-Michel;
Maquoi, Erik

Publication type:

Article

Discoidin Domain Receptor 1 Contributes to Tumorigenesis through Modulation of TGFBI Expression.

Published in:

PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0111515

By:

Rudra-Ganguly, Nandini;
Lowe, Christine;
Mattie, Michael;
Chang, Mi Sook;
Satpayev, Daulet;
Verlinsky, Alla;
An, Zili;
Hu, Liping;
Yang, Peng;
Challita-Eid, Pia;
Stover, David R.;
Pereira, Daniel S.

Publication type:

Article

Microarray Data Reveal Relationship between Jag1 and Ddr1 in Mouse Liver.

Published in:

PLoS ONE, 2013, v. 8, n. 12, p. 1, doi. 10.1371/journal.pone.0084383

By:

Underkoffler, Lara A.;
Carr, Erikka;
Nelson, Anthony;
Ryan, Matthew J.;
Schultz, Reiner;
Loomes, Kathleen M.

Publication type:

Article

Synthesis and biological evaluation of novel dasatinib analogues as potent DDR1 and DDR2 kinase inhibitors.

Published in:

Chemical Biology & Drug Design, 2017, v. 89, n. 3, p. 420, doi. 10.1111/cbdd.12863

By:

Liu, Lu;
Hussain, Muzammal;
Luo, Jinfeng;
Duan, Anna;
Chen, Chaonan;
Tu, Zhengchao;
Zhang, Jiancun

Publication type:

Article

3D culture enhances chemoresistance of ALL Jurkat cell line by increasing DDR1 expression.

Published in:

Experimental & Therapeutic Medicine, 2019, v. 17, n. 3, p. 1593

By:

Guo, Jun;
Zhao, Chunting;
Yao, Ruyong;
Sui, Aihua;
Sun, Lingjie;
Liu, Xiaodan;
Wu, Shaoling;
Su, Zhan;
Li, Tianlan;
Liu, Shanshan;
Gao, Yan;
Liu, Jiaxiu;
Feng, Xianqi;
Wang, Wei;
Zhao, Hongguo;
Cui, Zhongguang;
Li, Guanglun;
Meng, Fanjun

Publication type:

Article

Discoidin domain receptor 1 promotes hepatocellular carcinoma progression through modulation of SLC1A5 and the mTORC1 signaling pathway.

Published in:

Cellular Oncology (2211-3428), 2022, v. 45, n. 1, p. 163, doi. 10.1007/s13402-022-00659-8

By:

Pan, Yonglong;
Han, Mengzhen;
Zhang, Xiaochao;
He, Yi;
Yuan, Chaoyi;
Xiong, Yixiao;
Li, Xinxin;
Zeng, Chenglong;
Lu, Kan;
Zhu, He;
Lu, Xun;
Liu, Qiumeng;
Liang, Huifang;
Liao, Zhibin;
Ding, Zeyang;
Zhang, Zhanguo;
Chen, Xiaoping;
Zhang, Wanguang;
Zhang, Bixiang

Publication type:

Article

Effects of DDR1 on migration and adhesion of periodontal ligament cells and the underlying mechanism.

Published in:

Journal of Periodontal Research, 2022, v. 57, n. 3, p. 568, doi. 10.1111/jre.12986

By:

Wang, Yuhan;
Han, Bing;
Liu, Kaining;
Wang, Xiaoyan

Publication type:

Article

DDR1 promotes migration and invasion of breast cancer by modulating the Src-FAK signaling.

Published in:

Neoplasma, 2022, v. 69, n. 5, p. 1154, doi. 10.4149/neo_2022_220316N289

By:

Qing HAN;
Fei XIAO;
Lili MA;
Jinmei ZHOU;
Lan WANG;
Huang CHENG;
Jingjing ZHU;
Fuli YAO;
Jianxin LYU;
Linyong DU

Publication type:

Article

Nilotinib, a discoidin domain receptor 1 (DDR1) inhibitor, induces apoptosis and inhibits migration in breast cancer.

Published in:

Neoplasma, 2021, v. 68, n. 5, p. 975, doi. 10.4149/neo_2021_201126N1282

By:

Shuai WANG;
Yanping XIE;
Aina BAO;
Jing LI;
Tingting YE;
Chu YANG;
Shufang YU

Publication type:

Article

Assessment of Serum CXCL10 in the Sera of Patients with Active Vitiligo before and after Treatment with Oral Mini-Pulse Steroid Therapy versus Parenteral Corticosteroids Therapy: An Interventional Prospective Clinical Study.

Published in:

QJM: An International Journal of Medicine, 2024, v. 117, p. ii91, doi. 10.1093/qjmed/hcae175.212

By:

Abdel-Rahim Abdallah, Marwa M.;
Ahmed Soltan, Marwa Yassin;
Fahmy, Mary Wadie

Publication type:

Article

Genetic Analysis of Melanoma Types Using Japanese Genomic Database.

Published in:

Laryngoscope, 2025, v. 135, n. 1, p. 134, doi. 10.1002/lary.31676

By:

Matsumoto, Hayato;
Nagano, Hiromi;
Kyutoku, Takayuki;
Yamashita, Masaru

Publication type:

Article

Inhibition of discoidin domain receptor (DDR)-1 with nilotinib alters CSF miRNAs and is associated with reduced inflammation and vascular fibrosis in Alzheimer's disease.

Published in:

Journal of Neuroinflammation, 2023, v. 20, n. 1, p. 1, doi. 10.1186/s12974-023-02802-0

By:

Stevenson, Max;
Varghese, Rency;
Hebron, Michaeline L.;
Liu, Xiaoguang;
Ratliff, Nick;
Smith, Amelia;
Turner, R. Scott;
Moussa, Charbel

Publication type:

Article

Emerging strategies and translational advancements of DDR1 in oncology.

Published in:

Discover Oncology, 2025, p. 1, doi. 10.1007/s12672-025-02107-z

By:

Luo, Yuxi;
Liu, Tianxin;
Pei, Jinli;
Xu, Shengnan;
Liu, Jie;
Yu, Jinming

Publication type:

Article

Discovery of a broad spectrum antiproliferative agent with selectivity for DDR1 kinase: cell line-based assay, kinase panel, molecular docking, and toxicity studies.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2016, v. 31, n. 1, p. 158, doi. 10.3109/14756366.2015.1004057

By:

Elkamhawy, Ahmed;
Park, Jung-eun;
Cho, Nam-Chul;
Sim, Taebo;
Pae, Ae Nim;
Roh, Eun Joo

Publication type:

Article

Antibody-drug conjugates targeting DDR1 as a novel strategy for treatment of breast cancer.

Published in:

Journal of Drug Targeting, 2024, v. 32, n. 10, p. 1295, doi. 10.1080/1061186X.2024.2386621

By:

Tao, Yiran;
Lu, Ying;
Xue, Ting;
Lai, Qinhuai;
Song, Hengrui;
Chen, Xiaofeng;
Guo, Cuiyu;
Yang, Jinliang;
Wang, Yuxi

Publication type:

Article

Discoidin Domain Receptor 2: A New Target in Cancer.

Published in:

Oncology Research & Treatment, 2022, v. 45, n. 4, p. 205, doi. 10.1159/000519645

By:

Xu, Xiaoxiao;
Yu, Tong;
Wang, Zhenxing

Publication type:

Article

Focusing on discoidin domain receptors in premalignant and malignant liver diseases.

Published in:

Frontiers in Oncology, 2023, v. 13, p. 1, doi. 10.3389/fonc.2023.1123638

By:

Hang Gong;
Hui-Mei Xu;
De-Kui Zhang

Publication type:

Article

Discoid Domain Receptors Signaling in Macrophages-Mediated Diseases.

Published in:

International Journal of General Medicine, 2025, v. 18, p. 907, doi. 10.2147/IJGM.S487093

By:

Ma, Yaohui;
Gong, Hang;
Cheng, Long;
Zhang, Dekui

Publication type:

Article

Discoidin Domain Receptor 1, a Potential Biomarker and Therapeutic Target in Hepatocellular Carcinoma.

Published in:

International Journal of General Medicine, 2022, v. 15, p. 2037, doi. 10.2147/IJGM.S348110

By:

Wu, Linghong;
Zhao, Xinhua;
Ma, Huan;
Zhang, Lili;
Li, Xiaoan

Publication type:

Article

Can molecular dynamics simulations improve predictions of protein-ligand binding affinity with machine learning?

Published in:

Briefings in Bioinformatics, 2023, v. 24, n. 2, p. 1, doi. 10.1093/bib/bbad008

By:

Gu, Shukai;
Shen, Chao;
Yu, Jiahui;
Zhao, Hong;
Liu, Huanxiang;
Liu, Liwei;
Sheng, Rong;
Xu, Lei;
Wang, Zhe;
Hou, Tingjun;
Kang, Yu

Publication type:

Article

Coexpression of the discoidin domain receptor 1 gene with oligodendrocyte‐related and schizophrenia risk genes in the developing and adult human brain.

Published in:

Brain & Behavior, 2021, v. 11, n. 8, p. 1, doi. 10.1002/brb3.2309

By:

Muntané, Gerard;
Chillida, Marc;
Aranda, Selena;
Navarro, Arcadi;
Vilella, Elisabet

Publication type:

Article

Silencing of sinusoidal DDR1 reduces murine liver metastasis by colon carcinoma.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-75395-w

By:

Romayor, Irene;
Badiola, Iker;
Benedicto, Aitor;
Márquez, Joana;
Herrero, Alba;
Arteta, Beatriz;
Olaso, Elvira

Publication type:

Article

DDR1 Affects Metabolic Reprogramming in Breast Cancer Cells by Cross-Talking to the Insulin/IGF System.

Published in:

Biomolecules (2218-273X), 2021, v. 11, n. 7, p. 926, doi. 10.3390/biom11070926

By:

Vella, Veronica;
Giuliano, Marika;
Nicolosi, Maria Luisa;
Majorana, Maria Giovanna;
Marć, Małgorzata Anna;
Muoio, Maria Grazia;
Morrione, Andrea;
Maggiolini, Marcello;
Lappano, Rosamaria;
De Francesco, Ernestina Marianna;
Belfiore, Antonino

Publication type:

Article

Discoidin Domain Receptor-1 (DDR1) is Involved in Angiolymphatic Invasion in Oral Cancer.

Published in:

Cancers, 2020, v. 12, n. 4, p. 841, doi. 10.3390/cancers12040841

By:

Chen, Yu-Lian;
Tsai, Wan-Hua;
Ko, Ying-Chieh;
Lai, Ting-Yu;
Cheng, Ann-Joy;
Shiah, Shine-Gwo;
Hsiao, Jenn-Ren;
Chang, Jang-Yang;
Lin, Su-Fang

Publication type:

Article

Suppressing miR-199a-3p by promoter methylation contributes to tumor aggressiveness and cisplatin resistance of ovarian cancer through promoting DDR1 expression.

Published in:

Journal of Ovarian Research, 2017, v. 10, p. 1, doi. 10.1186/s13048-017-0333-4

By:

Yuao Deng;
Fang Zhao;
Liu Hui;
Xiuyun Li;
Danyu Zhang;
Wang Lin;
Zhiqiang Chen;
Yingxia Ning

Publication type:

Article

Dapagliflozin Inhibits Cell Adhesion to Collagen I and IV and Increases Ectodomain Proteolytic Cleavage of DDR1 by Increasing ADAM10 Activity.

Published in:

Molecules, 2020, v. 25, n. 3, p. 495, doi. 10.3390/molecules25030495

By:

Okada, Junichi;
Yamada, Eijiro;
Saito, Tsugumichi;
Yokoo, Hideaki;
Osaki, Aya;
Shimoda, Yoko;
Ozawa, Atsushi;
Nakajima, Yasuyo;
Pessin, Jeffrey E.;
Okada, Shuichi;
Yamada, Masanobu

Publication type:

Article

Discoidin domain receptor 1 activity drives an aggressive phenotype in gastric carcinoma.

Published in:

2017

By:

Hoon Hur;
In-Hye Ham;
Dakeun Lee;
Hyejin Jin;
Aguilera, Kristina Y.;
Hye Jeong Oh;
Sang-Uk Han;
Ji Eun Kwon;
Young-Bae Kim;
Ke Ding;
Brekken, Rolf A.;
Hur, Hoon;
Ham, In-Hye;
Lee, Dakeun;
Jin, Hyejin;
Oh, Hye Jeong;
Han, Sang-Uk;
Kwon, Ji Eun;
Kim, Young-Bae;
Ding, Ke

Publication type:

journal article

Discoidin domain receptor 1 as a promising biomarker for high-grade gliomas.

Published in:

Journal of Cancer Research & Therapeutics, 2023, v. 19, p. S285, doi. 10.4103/jcrt.jcrt_708_21

By:

Erdem, Dilek;
Gunaldi, Meral;
Karaman, Irem;
Adilay, Utku;
Yılmaz, İlhan Umit;
Eseoglu, Metehan;
Avcıkurt, Ayla;
Isıksacan, Nilgun;
Erdogan, Uzay;
Gunaldi, Omur

Publication type:

Article

Discoidin domain receptor 1 promotes lung adenocarcinoma migration via the AKT/snail signaling axis.

Published in:

Molecular Biology Reports, 2022, v. 49, n. 8, p. 7275, doi. 10.1007/s11033-022-07509-8

By:

Zhu, Jingjing;
Cheng, Huang;
Wang, Lan;
Xu, Weide;
Wang, Junqing;
Han, Qing;
Lee, Jong-ho;
Du, Linyong;
Lyu, Jianxin

Publication type:

Article

Improving drug discovery with a hybrid deep generative model using reinforcement learning trained on a Bayesian docking approximation.

Published in:

Journal of Computer-Aided Molecular Design, 2023, v. 37, n. 11, p. 507, doi. 10.1007/s10822-023-00523-3

By:

Xiong, Youjin;
Wang, Yiqing;
Wang, Yisheng;
Li, Chenmei;
Yusong, Peng;
Wu, Junyu;
Gu, Lingyun;
Butch, Christopher J.

Publication type:

Article

Ablation of Discoidin Domain Receptor 1 Provokes an Osteopenic Phenotype by Regulating Osteoblast/Osteocyte Autophagy and Apoptosis.

Published in:

Biomedicines, 2022, v. 10, n. 9, p. 2173, doi. 10.3390/biomedicines10092173

By:

Chou, Hsin-Chiao;
Lin, Sung-Yen;
Chou, Liang-Yin;
Ho, Mei-Ling;
Chuang, Shu-Chun;
Cheng, Tsung-Lin;
Kang, Lin;
Lin, Yi-Shan;
Wang, Yan-Hsiung;
Wei, Chun-Wang;
Chen, Chung-Hwan;
Wang, Chau-Zen

Publication type:

Article