Works matching IS 2397768X AND DT 2021 AND VI 5 AND IP 1

Results: 104

Emergence of mTOR mutation as an acquired resistance mechanism to AKT inhibition, and subsequent response to mTORC1/2 inhibition.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00240-w
By:
- Coleman, Niamh;
- Subbiah, Vivek;
- Pant, Shubham;
- Patel, Keyur;
- Roy-Chowdhuri, Sinchita;
- Yedururi, Sireesha;
- Johnson, Amber;
- Yap, Timothy A.;
- Rodon, Jordi;
- Shaw, Kenna;
- Meric-Bernstam, Funda
Publication type:
Article
Clinical response to nivolumab in an INI1-deficient pediatric chordoma correlates with immunogenic recognition of brachyury.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00238-4
By:
- Williamson, Laura M.;
- Rive, Craig M.;
- Di Francesco, Daniela;
- Titmuss, Emma;
- Chun, Hye-Jung E.;
- Brown, Scott D.;
- Milne, Katy;
- Pleasance, Erin;
- Lee, Anna F.;
- Yip, Stephen;
- Rosenbaum, Daniel G.;
- Hasselblatt, Martin;
- Johann, Pascal D.;
- Kool, Marcel;
- Harvey, Melissa;
- Dix, David;
- Renouf, Daniel J.;
- Holt, Robert A.;
- Nelson, Brad H.;
- Hirst, Martin
Publication type:
Article
High TGF-β signature predicts immunotherapy resistance in gynecologic cancer patients treated with immune checkpoint inhibition.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00242-8
By:
- Ni, Ying;
- Soliman, Ahmed;
- Joehlin-Price, Amy;
- Rose, Peter G.;
- Vlad, Anda;
- Edwards, Robert P.;
- Mahdi, Haider
Publication type:
Article
Clonal dynamics of BRAF-driven drug resistance in EGFR-mutant lung cancer.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00241-9
By:
- Schaufler, Diana;
- Ast, David F.;
- Tumbrink, Hannah L.;
- Abedpour, Nima;
- Maas, Lukas;
- Schwäbe, Ayla E.;
- Spille, Inga;
- Lennartz, Stefanie;
- Fassunke, Jana;
- Aldea, Mihaela;
- Besse, Benjamin;
- Planchard, David;
- Nogova, Lucia;
- Michels, Sebastian;
- Kobe, Carsten;
- Persigehl, Thorsten;
- Westphal, Theresa;
- Koleczko, Sophia;
- Fischer, Rieke;
- Weber, Jan-Phillip
Publication type:
Article
Early identification of disease progression in ALK-rearranged lung cancer using circulating tumor DNA analysis.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00239-3
By:
- Angeles, Arlou Kristina;
- Christopoulos, Petros;
- Yuan, Zhao;
- Bauer, Simone;
- Janke, Florian;
- Ogrodnik, Simon John;
- Reck, Martin;
- Schlesner, Matthias;
- Meister, Michael;
- Schneider, Marc A.;
- Dietz, Steffen;
- Stenzinger, Albrecht;
- Thomas, Michael;
- Sültmann, Holger
Publication type:
Article
Selective KRAS G12C inhibitors in non-small cell lung cancer: chemistry, concurrent pathway alterations, and clinical outcomes.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00237-5
By:
- Palma, Gabriela;
- Khurshid, Faisal;
- Lu, Kevin;
- Woodward, Brian;
- Husain, Hatim
Publication type:
Article
FOXP3+ T cells in uterine sarcomas are associated with favorable prognosis, low extracellular matrix expression and reduced YAP activation.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00236-6
By:
- Gultekin, Okan;
- Gonzalez-Molina, Jordi;
- Hardell, Elin;
- Moyano-Galceran, Lidia;
- Mitsios, Nicholas;
- Mulder, Jan;
- Kokaraki, Georgia;
- Isaksson, Anders;
- Sarhan, Dhifaf;
- Lehti, Kaisa;
- Carlson, Joseph W.
Publication type:
Article
Pharmacogenomics characterization of the MDM2 inhibitor MI-773 reveals candidate tumours and predictive biomarkers.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00235-7
By:
- Vuaroqueaux, Vincent;
- Hendriks, Hans R.;
- Al-Hasani, Hoor;
- Peille, Anne-Lise;
- Das, Samayita;
- Fiebig, Heinz-Herbert
Publication type:
Article
An analysis of research biopsy core variability from over 5000 prospectively collected core samples.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00234-8
By:
- Bhamidipati, Deepak;
- Verma, Anuj;
- Sui, Dawen;
- Maru, Dipen;
- Mathew, Grace;
- Lang, Wenhua;
- Posadas, Juan;
- Hein, Joshua;
- Kopetz, Scott;
- Futreal, Andrew;
- Wistuba, Ignacio I.;
- Gupta, Sanjay;
- Lee, J. Jack;
- Overman, Michael J.;
- Tam, Alda L.
Publication type:
Article
GD2 CAR T cells against human glioblastoma.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00233-9
By:
- Prapa, Malvina;
- Chiavelli, Chiara;
- Golinelli, Giulia;
- Grisendi, Giulia;
- Bestagno, Marco;
- Di Tinco, Rosanna;
- Dall'Ora, Massimiliano;
- Neri, Giovanni;
- Candini, Olivia;
- Spano, Carlotta;
- Petrachi, Tiziana;
- Bertoni, Laura;
- Carnevale, Gianluca;
- Pugliese, Giuseppe;
- Depenni, Roberta;
- Feletti, Alberto;
- Iaccarino, Corrado;
- Pavesi, Giacomo;
- Dominici, Massimo
Publication type:
Article
Molecular differences between lymph nodes and distant metastases compared with primaries in colorectal cancer patients.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00230-y
By:
- Puccini, Alberto;
- Seeber, Andreas;
- Xiu, Joanne;
- Goldberg, Richard M.;
- Soldato, Davide;
- Grothey, Axel;
- Shields, Anthony F.;
- Salem, Mohamed E.;
- Battaglin, Francesca;
- Berger, Martin D.;
- El-Deiry, Wafik S.;
- Tokunaga, Ryuma;
- Naseem, Madiha;
- Zhang, Wu;
- Arora, Sukeshi Patel;
- Khushman, Moh'd M.;
- Hall, Michael J.;
- Philip, Philip A.;
- Marshall, John L.;
- Korn, W. Michael
Publication type:
Article
Multiomics analysis of serial PARP inhibitor treated metastatic TNBC inform on rational combination therapies.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00232-w
By:
- Labrie, Marilyne;
- Li, Allen;
- Creason, Allison;
- Betts, Courtney;
- Keck, Jamie;
- Johnson, Brett;
- Sivagnanam, Shamilene;
- Boniface, Christopher;
- Ma, Hongli;
- Blucher, Aurora;
- Chang, Young Hwan;
- Chin, Koei;
- Vuky, Jacqueline;
- Guimaraes, Alexander R.;
- Downey, Molly;
- Lim, Jeong Youn;
- Gao, Lina;
- Siex, Kiara;
- Parmar, Swapnil;
- Kolodzie, Annette
Publication type:
Article
Evolution of MET and NRAS gene amplification as acquired resistance mechanisms in EGFR mutant NSCLC.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00231-x
By:
- Peters, T. L.;
- Patil, T.;
- Le, A. T.;
- Davies, K. D.;
- Brzeskiewicz, P. M.;
- Nijmeh, H.;
- Bao, L.;
- Camidge, D. R.;
- Aisner, D. L.;
- Doebele, R. C.
Publication type:
Article
Comprehensive RNA analysis of CSF reveals a role for CEACAM6 in lung cancer leptomeningeal metastases.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00228-6
By:
- Li, Yingmei;
- Polyak, Dina;
- Lamsam, Layton;
- Connolly, Ian David;
- Johnson, Eli;
- Khoeur, Lina Khav;
- Andersen, Stephanie;
- Granucci, Monica;
- Stanley, Geoff;
- Liu, Boxiang;
- Nagpal, Seema;
- Hayden Gephart, Melanie
Publication type:
Article
Genomic context of NTRK1/2/3 fusion-positive tumours from a large real-world population.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00206-y
By:
- Westphalen, C. B.;
- Krebs, M. G.;
- Le Tourneau, C.;
- Sokol, E. S.;
- Maund, S. L.;
- Wilson, T. R.;
- Jin, D. X.;
- Newberg, J. Y.;
- Fabrizio, D.;
- Veronese, L.;
- Thomas, M.;
- de Braud, F.
Publication type:
Article
BAP1 methylation: a prognostic marker of uveal melanoma metastasis.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00226-8
By:
- Bakhoum, Mathieu F.;
- Curtis, Ellis J.;
- Goldbaum, Michael H.;
- Mischel, Paul S.
Publication type:
Article
Genetic mutation and biological pathway prediction based on whole slide images in breast carcinoma using deep learning.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00225-9
By:
- Qu, Hui;
- Zhou, Mu;
- Yan, Zhennan;
- Wang, He;
- Rustgi, Vinod K.;
- Zhang, Shaoting;
- Gevaert, Olivier;
- Metaxas, Dimitris N.
Publication type:
Article
Systematic tissue collection during clinical breast biopsy is feasible, safe and enables high-content translational analyses.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00224-w
By:
- Koh, Siang-Boon;
- Dontchos, Brian N.;
- Bossuyt, Veerle;
- Edmonds, Christine;
- Cristea, Simona;
- Melkonjan, Nsan;
- Mortensen, Lindsey;
- Ma, Annie;
- Beyerlin, Kassidy;
- Denault, Elyssa;
- Niehoff, Elizabeth;
- Hirz, Taghreed;
- Sykes, David B.;
- Michor, Franziska;
- Specht, Michelle;
- Lehman, Constance;
- Ellisen, Leif W.;
- Spring, Laura M.
Publication type:
Article
Author Correction: Genomic context of NTRK1/2/3 fusion-positive tumours from a large real-world population.
Published in:
2021
By:
- Westphalen, C. B.;
- Krebs, M. G.;
- Le Tourneau, C.;
- Sokol, E. S.;
- Maund, S. L.;
- Wilson, T. R.;
- Jin, D. X.;
- Newberg, J. Y.;
- Fabrizio, D.;
- Veronese, L.;
- Thomas, M.;
- de Braud, F.
Publication type:
Correction Notice
Circulating tumor DNA is readily detectable among Ghanaian breast cancer patients supporting non-invasive cancer genomic studies in Africa.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00219-7
By:
- Ahuno, Samuel Terkper;
- Doebley, Anna-Lisa;
- Ahearn, Thomas U.;
- Yarney, Joel;
- Titiloye, Nicholas;
- Hamel, Nancy;
- Adjei, Ernest;
- Clegg-Lamptey, Joe-Nat;
- Edusei, Lawrence;
- Awuah, Baffour;
- Song, Xiaoyu;
- Vanderpuye, Verna;
- Abubakar, Mustapha;
- Duggan, Maire;
- Stover, Daniel G.;
- Nyarko, Kofi;
- Bartlett, John M. S.;
- Aitpillah, Francis;
- Ansong, Daniel;
- Gardner, Kevin L.
Publication type:
Article
How I faced my prostate cancer: a molecular biologist's perspective.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00229-5
By:
- Zuradelli, Monica;
- Lazzeri, Massimo;
- Lopci, Egesta;
- Zucali, Paolo Andrea;
- Balzarini, Luca;
- Guazzoni, Giorgio;
- Colombo, Piergiuseppe;
- Scorsetti, Marta;
- Franzese, Ciro;
- Asselta, Rosanna;
- Soldà, Giulia;
- Duga, Stefano
Publication type:
Article
Author Correction: Circulating tumor cell heterogeneity in neuroendocrine prostate cancer by single cell copy number analysis.
Published in:
2021
By:
- Conteduca, Vincenza;
- Ku, Sheng-Yu;
- Fernandez, Luisa;
- Dago-Rodriquez, Angel;
- Lee, Jerry;
- Jendrisak, Adam;
- Slade, Megan;
- Gilbertson, Cole;
- Manohar, Jyothi;
- Sigouros, Michael;
- Wang, Yipeng;
- Dittamore, Ryan;
- Wenstrup, Rick;
- Mosquera, Juan Miguel;
- Schonhoft, Joseph D.;
- Beltran, Himisha
Publication type:
Correction Notice
Real-world data analyses unveiled the immune-related adverse effects of immune checkpoint inhibitors across cancer types.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00223-x
By:
- Wang, Feicheng;
- Yang, Shihao;
- Palmer, Nathan;
- Fox, Kathe;
- Kohane, Isaac S.;
- Liao, Katherine P.;
- Yu, Kun-Hsing;
- Kou, S. C.
Publication type:
Article
Genomic characterization and outcome evaluation of kinome fusions in lung cancer revealed novel druggable fusions.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00221-z
By:
- Li, Binghao;
- Qu, Hao;
- Zhang, Jing;
- Pan, Weibo;
- Liu, Meng;
- Yan, Xiaobo;
- Huang, Xin;
- He, Xuexin;
- Lin, Dong;
- Liu, Sisi;
- Guan, Ruting;
- Wu, Yong;
- Ou, Qiuxiang;
- Bao, Hua;
- Xu, Youbin;
- Wu, Xue;
- Shao, Yang;
- Lin, Nong
Publication type:
Article
Targeting extracellular and juxtamembrane FGFR2 mutations in chemotherapy-refractory cholangiocarcinoma.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00220-0
By:
- Bitzer, Michael;
- Spahn, Stephan;
- Babaei, Sepideh;
- Horger, Marius;
- Singer, Stephan;
- Schulze-Osthoff, Klaus;
- Missios, Pavlos;
- Gatidis, Sergios;
- Nann, Dominik;
- Mattern, Sven;
- Scheble, Veit;
- Nikolaou, Konstantin;
- Armeanu-Ebinger, Sorin;
- Schulze, Martin;
- Schroeder, Christopher;
- Biskup, Saskia;
- Beha, Janina;
- Claassen, Manfred;
- Ruhm, Kristina;
- Poso, Antti
Publication type:
Article
Artificial intelligence for the next generation of precision oncology.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00216-w
By:
- Ballester, Pedro J.;
- Carmona, Javier
Publication type:
Article
Clinical, genetic and pharmacological data support targeting the MEK5/ERK5 module in lung cancer.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00218-8
By:
- Sánchez-Fdez, Adrián;
- Re-Louhau, María Florencia;
- Rodríguez-Núñez, Pablo;
- Ludeña, Dolores;
- Matilla-Almazán, Sofía;
- Pandiella, Atanasio;
- Esparís-Ogando, Azucena
Publication type:
Article
Circulating tumor cell heterogeneity in neuroendocrine prostate cancer by single cell copy number analysis.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00211-1
By:
- Conteduca, Vincenza;
- Ku, Sheng-Yu;
- Fernandez, Luisa;
- Dago-Rodriquez, Angel;
- Lee, Jerry;
- Jendrisak, Adam;
- Slade, Megan;
- Gilbertson, Cole;
- Manohar, Jyothi;
- Sigouros, Michael;
- Wang, Yipeng;
- Dittamore, Ryan;
- Wenstrup, Rick;
- Mosquera, Juan Miguel;
- Schonhoft, Joseph D.;
- Beltran, Himisha
Publication type:
Article
Acquired JAK2 mutations confer resistance to JAK inhibitors in cell models of acute lymphoblastic leukemia.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00215-x
By:
- Downes, Charlotte E. J.;
- McClure, Barbara J.;
- Bruning, John B.;
- Page, Elyse;
- Breen, James;
- Rehn, Jacqueline;
- Yeung, David T.;
- White, Deborah L.
Publication type:
Article
Retraction Note: Birinapant sensitizes platinum-resistant carcinomas with high levels of cIAP to carboplatin therapy.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00217-9
By:
- La, V.;
- Fujikawa, R.;
- Janzen, D. M.;
- Nunez, M.;
- Bainvoll, L.;
- Hwang, L.;
- Faull, K.;
- Lawson, G.;
- Memarzadeh, S.
Publication type:
Article
A phase I/II study of rovalpituzumab tesirine in delta-like 3—expressing advanced solid tumors.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00214-y
By:
- Mansfield, Aaron S.;
- Hong, David S.;
- Hann, Christine L.;
- Farago, Anna F.;
- Beltran, Himisha;
- Waqar, Saiama N.;
- Hendifar, Andrew E.;
- Anthony, Lowell B.;
- Taylor, Matthew H.;
- Bryce, Alan H.;
- Tagawa, Scott T.;
- Lewis, Karl;
- Niu, Jiaxin;
- Chung, Christine H.;
- Cleary, James M.;
- Rossi, Michael;
- Ludwig, Carrianne;
- Valenzuela, Ricardo;
- Luo, Yan;
- Aggarwal, Rahul
Publication type:
Article
Inter-eye genomic heterogeneity in bilateral retinoblastoma via aqueous humor liquid biopsy.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00212-0
By:
- Wong, Elyssa Y.;
- Xu, Liya;
- Shen, Lishuang;
- Kim, Mary E.;
- Polski, Ashley;
- Prabakar, Rishvanth K.;
- Shah, Rachana;
- Jubran, Rima;
- Kim, Jonathan W.;
- Biegel, Jaclyn A.;
- Gai, Xiaowu;
- Kuhn, Peter;
- Hicks, James;
- Berry, Jesse L.
Publication type:
Article
Quantitative MRI-based radiomics for noninvasively predicting molecular subtypes and survival in glioma patients.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00205-z
By:
- Yan, Jing;
- Zhang, Bin;
- Zhang, Shuaitong;
- Cheng, Jingliang;
- Liu, Xianzhi;
- Wang, Weiwei;
- Dong, Yuhao;
- Zhang, Lu;
- Mo, Xiaokai;
- Chen, Qiuying;
- Fang, Jin;
- Wang, Fei;
- Tian, Jie;
- Zhang, Shuixing;
- Zhang, Zhenyu
Publication type:
Article
Bayesian multi-source regression and monocyte-associated gene expression predict BCL-2 inhibitor resistance in acute myeloid leukemia.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00209-9
By:
- White, Brian S.;
- Khan, Suleiman A.;
- Mason, Mike J.;
- Ammad-ud-din, Muhammad;
- Potdar, Swapnil;
- Malani, Disha;
- Kuusanmäki, Heikki;
- Druker, Brian J.;
- Heckman, Caroline;
- Kallioniemi, Olli;
- Kurtz, Stephen E.;
- Porkka, Kimmo;
- Tognon, Cristina E.;
- Tyner, Jeffrey W.;
- Aittokallio, Tero;
- Wennerberg, Krister;
- Guinney, Justin
Publication type:
Article
TCERG1L allelic variation is associated with cisplatin-induced hearing loss in childhood cancer, a PanCareLIFE study.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00178-z
By:
- Meijer, A. J. M.;
- Diepstraten, F. A.;
- Langer, T.;
- Broer, L.;
- Domingo, I. K.;
- Clemens, E.;
- Uitterlinden, A. G.;
- de Vries, A. C. H.;
- van Grotel, M.;
- Vermeij, W. P.;
- Ozinga, R. A.;
- Binder, H.;
- Byrne, J.;
- van Dulmen-den Broeder, E.;
- Garrè, M. L.;
- Grabow, D.;
- Kaatsch, P.;
- Kaiser, M.;
- Kenborg, L.;
- Winther, J. F.
Publication type:
Article
Preoperative clinical and tumor genomic features associated with pathologic lymph node metastasis in clinical stage I and II lung adenocarcinoma.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00210-2
By:
- Caso, Raul;
- Connolly, James G.;
- Zhou, Jian;
- Tan, Kay See;
- Choi, James J.;
- Jones, Gregory D.;
- Mastrogiacomo, Brooke;
- Sanchez-Vega, Francisco;
- Nguyen, Bastien;
- Rocco, Gaetano;
- Molena, Daniela;
- Sihag, Smita;
- Adusumilli, Prasad S.;
- Bott, Matthew J.;
- Jones, David R.
Publication type:
Article
PERK mediates resistance to BRAF inhibition in melanoma with impaired PTEN.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00207-x
By:
- Qin, Yifei;
- Zuo, Qiang;
- Huang, Lei;
- Huang, Liping;
- Merlino, Glenn;
- Yu, Yanlin
Publication type:
Article
Comprehensive functional evaluation of variants of fibroblast growth factor receptor genes in cancer.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00204-0
By:
- Nakamura, Ikuko Takeda;
- Kohsaka, Shinji;
- Ikegami, Masachika;
- Ikeuchi, Hiroshi;
- Ueno, Toshihide;
- Li, Kunhua;
- Beyett, Tyler S.;
- Koyama, Takafumi;
- Shimizu, Toshio;
- Yamamoto, Noboru;
- Takahashi, Fumiyuki;
- Takahashi, Kazuhisa;
- Eck, Michael J.;
- Mano, Hiroyuki
Publication type:
Article
Circulating tumor cell copy-number heterogeneity in ALK-rearranged non-small-cell lung cancer resistant to ALK inhibitors.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00203-1
By:
- Oulhen, Marianne;
- Pawlikowska, Patrycja;
- Tayoun, Tala;
- Garonzi, Marianna;
- Buson, Genny;
- Forcato, Claudio;
- Manaresi, Nicolò;
- Aberlenc, Agathe;
- Mezquita, Laura;
- Lecluse, Yann;
- Lavaud, Pernelle;
- Naltet, Charles;
- Planchard, David;
- Besse, Benjamin;
- Farace, Françoise
Publication type:
Article
Combined FGFR and Akt pathway inhibition abrogates growth of FGFR1 overexpressing EGFR-TKI-resistant NSCLC cells.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00208-w
By:
- Terp, Mikkel G.;
- Jacobsen, Kirstine;
- Molina, Miguel Angel;
- Karachaliou, Niki;
- Beck, Hans C.;
- Bertran-Alamillo, Jordi;
- Giménez-Capitán, Ana;
- Cardona, Andrés F.;
- Rosell, Rafael;
- Ditzel, Henrik J.
Publication type:
Article
Genomic context of NTRK1/2/3 fusion-positive tumours from a large real-world population.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00206-y
By:
- Westphalen, C. B.;
- Krebs, M. G.;
- Le Tourneau, C.;
- Sokol, E. S.;
- Maund, S. L.;
- Wilson, T. R.;
- Jin, D. X.;
- Newberg, J. Y.;
- Fabrizio, D.;
- Veronese, L.;
- Thomas, M.;
- de Braud, F.
Publication type:
Article
Validation of a liquid biopsy assay with molecular and clinical profiling of circulating tumor DNA.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00202-2
By:
- Finkle, Justin D.;
- Boulos, Hala;
- Driessen, Terri M.;
- Lo, Christine;
- Blidner, Richard A.;
- Hafez, Ashraf;
- Khan, Aly A.;
- Lozac'hmeur, Ariane;
- McKinnon, Kelly E.;
- Perera, Jason;
- Zhu, Wei;
- Dowlati, Afshin;
- White, Kevin P.;
- Tell, Robert;
- Beaubier, Nike
Publication type:
Article
Bevacizumab improves tumor infiltration of mature dendritic cells and effector T-cells in triple-negative breast cancer patients.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00197-w
By:
- Boucher, Yves;
- Kumar, Ashwin S.;
- Posada, Jessica M.;
- Gjini, Evisa;
- Pfaff, Kathleen;
- Lipschitz, Mikel;
- Lako, Ana;
- Duda, Dan G.;
- Rodig, Scott J.;
- Hodi, F. Stephen;
- Jain, Rakesh K.
Publication type:
Article
Pentraxin 3 is a stromally-derived biomarker for detection of pancreatic ductal adenocarcinoma.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00192-1
By:
- Goulart, Michelle R.;
- Watt, Jennifer;
- Siddiqui, Imran;
- Lawlor, Rita T.;
- Imrali, Ahmet;
- Hughes, Christine;
- Saad, Amina;
- ChinAleong, Joanne;
- Hurt, Chris;
- Cox, Catrin;
- Salvia, Roberto;
- Mantovani, Alberto;
- Crnogorac-Jurcevic, Tatjana;
- Mukherjee, Somnath;
- Scarpa, Aldo;
- Allavena, Paola;
- Kocher, Hemant M.
Publication type:
Article
Genetic program activity delineates risk, relapse, and therapy responsiveness in multiple myeloma.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00185-0
By:
- Wall, Matthew A.;
- Turkarslan, Serdar;
- Wu, Wei-Ju;
- Danziger, Samuel A.;
- Reiss, David J.;
- Mason, Mike J.;
- Dervan, Andrew P.;
- Trotter, Matthew W. B.;
- Bassett, Douglas;
- Hershberg, Robert M.;
- Lomana, Adrián López García de;
- Ratushny, Alexander V.;
- Baliga, Nitin S.
Publication type:
Article
Criteria-based curation of a therapy-focused compendium to support treatment recommendations in precision oncology.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00194-z
By:
- Lin, Frank P.;
- Thavaneswaran, Subotheni;
- Grady, John P.;
- Ballinger, Mandy;
- Kansara, Maya;
- Oakes, Samantha R.;
- Desai, Jayesh;
- Lee, Chee Khoon;
- Simes, John;
- Thomas, David M.
Publication type:
Article
A computational method for prioritizing targeted therapies in precision oncology: performance analysis in the SHIVA01 trial.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00191-2
By:
- Petak, Istvan;
- Kamal, Maud;
- Dirner, Anna;
- Bieche, Ivan;
- Doczi, Robert;
- Mariani, Odette;
- Filotas, Peter;
- Salomon, Anne;
- Vodicska, Barbara;
- Servois, Vincent;
- Varkondi, Edit;
- Gentien, David;
- Tihanyi, Dora;
- Tresca, Patricia;
- Lakatos, Dora;
- Servant, Nicolas;
- Deri, Julia;
- du Rusquec, Pauline;
- Hegedus, Csilla;
- Bello Roufai, Diana
Publication type:
Article
Comprehensive molecular profiling of pulmonary pleomorphic carcinoma.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00201-3
By:
- Nagano, Masaaki;
- Kohsaka, Shinji;
- Hayashi, Takuo;
- Ueno, Toshihide;
- Kojima, Shinya;
- Shinozaki-Ushiku, Aya;
- Morita, Shigeki;
- Tsuda, Masumi;
- Tanaka, Shinya;
- Shinohara, Toshiya;
- Omori, Yuko;
- Sugaya, Fumiko;
- Kato, Hiroaki;
- Narita, Yoshiaki;
- Nakajima, Jun;
- Suzuki, Kenji;
- Takamochi, Kazuya;
- Mano, Hiroyuki
Publication type:
Article
The pan-cancer landscape of crosstalk between epithelial-mesenchymal transition and immune evasion relevant to prognosis and immunotherapy response.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00200-4
By:
- Wang, Guangyu;
- Xu, Dandan;
- Zhang, Zicheng;
- Li, Xinhui;
- Shi, Jiaqi;
- Sun, Jie;
- Liu, Huan-Zhong;
- Li, Xiaobo;
- Zhou, Meng;
- Zheng, Tongsen
Publication type:
Article
A subset of lung cancer cases shows robust signs of homologous recombination deficiency associated genomic mutational signatures.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00199-8
By:
- Diossy, Miklos;
- Sztupinszki, Zsofia;
- Borcsok, Judit;
- Krzystanek, Marcin;
- Tisza, Viktoria;
- Spisak, Sandor;
- Rusz, Orsolya;
- Timar, Jozsef;
- Csabai, István;
- Fillinger, Janos;
- Moldvay, Judit;
- Pedersen, Anders Gorm;
- Szuts, David;
- Szallasi, Zoltan
Publication type:
Article