Works matching DE "FARNESOID X receptor"

Results: 980

Challenges of UDCA Monotherapy for CHILI: High Recurrence Rate of Bile Duct Injury With Potential Immune Interference.

Published in:

Liver International, 2025, v. 45, n. 6, p. 1, doi. 10.1111/liv.70157

By:

Kou, Liqiu;
Yang, Zongyu;
Liu, Fusong;
Liao, Songjie

Publication type:

Article

The Role of the Gut Microbiota in Female Reproductive and Gynecological Health: Insights into Endometrial Signaling Pathways.

Published in:

Life (2075-1729), 2025, v. 15, n. 5, p. 762, doi. 10.3390/life15050762

By:

Escorcia Mora, Patricia;
Valbuena, Diana;
Diez-Juan, Antonio

Publication type:

Article

Protective Effect of Obeticholic Acid on Sepsis-Induced Liver Dysfunction via Regulating Bile Acid Homeostasis.

Published in:

Pharmaceuticals (14248247), 2025, v. 18, n. 5, p. 763, doi. 10.3390/ph18050763

By:

Wang, Jiahui;
Ma, Li;
An, Yuan;
Ge, Yan;
Xu, Dan;
Mao, Enqiang

Publication type:

Article

FXR agonists for MASH therapy: Lessons and perspectives from obeticholic acid.

Published in:

Medicinal Research Reviews, 2024, v. 44, n. 2, p. 568, doi. 10.1002/med.21991

By:

Wang, Kang;
Zhang, Yuecan;
Wang, Guangji;
Hao, Haiping;
Wang, Hong

Publication type:

Article

Expert insights: The potential role of the gut microbiome‐bile acid‐brain axis in the development and progression of Alzheimer's disease and hepatic encephalopathy.

Published in:

Medicinal Research Reviews, 2020, v. 40, n. 4, p. 1496, doi. 10.1002/med.21653

By:

Jia, Wei;
Rajani, Cynthia;
Kaddurah‐Daouk, Rima;
Li, Houkai

Publication type:

Article

Cholesterol-lowering effects of taurine through the reduction of ileal FXR signaling due to the alteration of ileal bile acid composition.

Published in:

Amino Acids, 2021, v. 53, n. 10, p. 1523, doi. 10.1007/s00726-021-03068-7

By:

Miyata, Masaaki;
Tanaka, Tomoyuki;
Takahashi, Kazuho;
Funaki, Akihiro;
Sugiura, Yoshimasa

Publication type:

Article

What Comes after Ursodeoxycholic Acid in Primary Biliary Cholangitis?

Published in:

Digestive Diseases, 2017, v. 35, n. 4, p. 359, doi. 10.1159/000467547

By:

Wong, Lin Lee;
Hegade, Vinod S.;
Jones, David E.J.

Publication type:

Article

Protective Effect of Dapagliflozin against Non-alcoholic Fatty Liver in Rats AMPK/SIRT1 Pathway Activation.

Published in:

Zagazig University Medical Journal, 2024, v. 30, n. 9, p. 4391, doi. 10.21608/zumj.2024.306374.3487

By:

Muhammed Abdulaziz Alsafty, Shaimaa Ashraf;
Abd El Motteleb, Dalia M.;
Sekinah, Ameen M.;
EL-sayed, Yassmen Mahmoud

Publication type:

Article

Obeticholic Acid Inhibit Mitochondria Dysfunction Via Regulating ERK1/2‐DRP Pathway to Exert Protective Effect on Lipopolysaccharide‐Induced Myocardial Injury.

Published in:

Advanced Biology, 2024, v. 8, n. 7, p. 1, doi. 10.1002/adbi.202300576

By:

Miao, Huijie;
Tang, Xiaomeng;
Cui, Yun;
Shi, Jingyi;
Xiong, Xi;
Wang, Chunxia;
Zhang, Yucai

Publication type:

Article

Assessing the Relationship Between Intrahepatic Cholestasis of Pregnancy and Exogenous Progesterone Intake.

Published in:

Jinekoloji-Obstetrik & Neonatoloji Tip Dergisi, 2024, v. 21, n. 2, p. 57, doi. 10.38136/jgon.1410939

By:

CENDEK, BUSRA DEMİR;
DAGDEVİREN, GULSAH;
CELEN, SEVKİ;
CAGLAR, ALİTURHAN

Publication type:

Article

功效性米粉对高脂诱导小鼠血脂的影响.

Published in:

Food Research & Development, 2025, v. 46, n. 9, p. 7, doi. 10.12161/j.issn.1005‐6521.2025.09.002

By:

熊志伟;
张文君;
陶悦;
韩慧缃;
梁伟

Publication type:

Article

Farnesoid X receptor in chronic liver diseases: an immunohistochemical study.

Published in:

Journal of Immunoassay & Immunochemistry, 2023, v. 44, n. 5/6, p. 381, doi. 10.1080/15321819.2023.2242920

By:

Sweed, Dina;
Holah, Nanis Shawky;
Karman, Esraa;
Asaad, Nancy;
Mahmoud, Shereen

Publication type:

Article

Antitubercular drugs induced liver injury: an updated insight into molecular mechanisms.

Published in:

Drug Metabolism Reviews, 2023, v. 55, n. 3, p. 239, doi. 10.1080/03602532.2023.2215478

By:

Ezhilarasan, Devaraj

Publication type:

Article

Oleanolic acid induces hepatic injury by disrupting hepatocyte tight junction and dysregulation of farnesoid X receptor‐mediated bile acid efflux transporters.

Published in:

Journal of Applied Toxicology, 2024, v. 44, n. 11, p. 1725, doi. 10.1002/jat.4667

By:

Zeng, Li;
Huang, Jianxiang;
Wang, Yi;
Hu, Yan;
Zhou, Shaoyu;
Lu, Yuanfu

Publication type:

Article

Allocholic acid protects against α‐naphthylisothiocyanate‐induced cholestasis in mice by ameliorating disordered bile acid homeostasis.

Published in:

Journal of Applied Toxicology, 2024, v. 44, n. 4, p. 582, doi. 10.1002/jat.4562

By:

Han, Xue;
Lin, Chuyi;
Liu, Huijie;
Li, Shan;
Hu, Bei;
Zhang, Lei

Publication type:

Article

Colchicine disrupts bile acid metabolic homeostasis by affecting the enterohepatic circulation in mice.

Published in:

Journal of Applied Toxicology, 2024, v. 44, n. 6, p. 863, doi. 10.1002/jat.4587

By:

Shi, Yongpeng;
Wei, Li;
Jin, Fang;
Wang, Ji;
Cao, Hanwen;
Yang, Ying;
Gao, Lan

Publication type:

Article

The cardiovascular toxicity of clozapine in embryonic zebrafish and RNA sequencing‐based transcriptome analysis.

Published in:

Journal of Applied Toxicology, 2024, v. 44, n. 2, p. 175, doi. 10.1002/jat.4530

By:

Ding, Zijiao;
Jia, Huiting;
Yang, Ziqian;
Yao, Nan;
Wang, Yunyun

Publication type:

Article

AMP‐activated protein kinase‐farnesoid X receptor pathway contributes to oleanolic acid‐induced liver injury.

Published in:

Journal of Applied Toxicology, 2023, v. 43, n. 8, p. 1201, doi. 10.1002/jat.4456

By:

Huang, Jianxiang;
Liao, Songjie;
Fu, Xiaolong;
Wang, Yi;
Zhou, Shaoyu;
Lu, Yuanfu

Publication type:

Article

The choleretic role of tauroursodeoxycholic acid exacerbates alpha‐naphthylisothiocyanate induced cholestatic liver injury through the FXR/BSEP pathway.

Published in:

Journal of Applied Toxicology, 2023, v. 43, n. 7, p. 1095, doi. 10.1002/jat.4446

By:

Zhao, Jing;
Song, Guochao;
Weng, Fengyi;
Li, Yue;
Zou, Bin;
Jin, Jingyi;
Yan, Dongming;
Sun, Xin;
Liu, Chenghai;
Qiu, Fu‐rong

Publication type:

Article

Obeticholic acid improved triptolide/lipopolysaccharide‐induced hepatotoxicity by inhibiting caspase‐11‐GSDMD pyroptosis pathway.

Published in:

Journal of Applied Toxicology, 2023, v. 43, n. 4, p. 599, doi. 10.1002/jat.4410

By:

Liang, Peishi;
Zhou, Shaoyun;
Yuan, Ziqiao;
Zhang, Luyong;
Jiang, Zhenzhou;
Yu, Qinwei

Publication type:

Article

Farnesoid X receptor contributes to oleanolic acid‐induced cholestatic liver injury in mice.

Published in:

Journal of Applied Toxicology, 2022, v. 42, n. 8, p. 1323, doi. 10.1002/jat.4298

By:

Feng, Hong;
Hu, Yan;
Zhou, Shaoyu;
Lu, Yuanfu

Publication type:

Article

Implications for Farnesoid X Receptor Signaling on Bile Acid Metabolism as a Potential Therapeutic Strategy for Nonalcoholic Fatty Liver Disease.

Published in:

Korean Journal of Obesity (2383-899X), 2016, v. 25, n. 4, p. 167, doi. 10.7570/kjo.2016.25.4.167

By:

Hyekyung Yang;
Cheol-Young Park

Publication type:

Article

The Role of the Gut Microbiota in Lipid and Lipoprotein Metabolism.

Published in:

Journal of Clinical Medicine, 2019, v. 8, n. 12, p. 2227, doi. 10.3390/jcm8122227

By:

Yu, Yijing;
Raka, Fitore;
Adeli, Khosrow

Publication type:

Article

Pregnane X receptor activation induces liver enlargement and regeneration and simultaneously promotes the metabolic activity of CYP3A1/2 and CYP2C6/11 in rats.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2024, v. 135, n. 2, p. 148, doi. 10.1111/bcpt.14041

By:

Bi, Guofang;
Liang, Fengting;
Wu, Ting;
Wang, Peng;
Jiang, Xiaowen;
Hu, Shuang;
Wu, Chenghua;
Zhou, Wenhong;
Guo, Jiayin;
Yang, Xiao;
Fang, Jian‐hong;
Chen, Wenying;
Bi, Huichang

Publication type:

Article

The role of peroxisome proliferator‐activated receptors in the regulation of bile acid metabolism.

Published in:

Basic & Clinical Pharmacology & Toxicology, 2024, v. 134, n. 3, p. 315, doi. 10.1111/bcpt.13971

By:

Sun, Yuqing;
Zhang, Luyong;
Jiang, Zhenzhou

Publication type:

Article

Bile Acid Sodium Symporter BASS6 Can Transport Glycolate and Is Involved in Photorespiratory Metabolism in Arabidopsis thaliana.

Published in:

Plant Cell, 2017, v. 29, n. 4, p. 808, doi. 10.1105/tpc.16.00775

By:

South, Paul F.;
Walker, Berkley J.;
Cavanagh, Amanda P.;
Rolland, Vivien;
Badger, Murray;
Ort, Donald R.

Publication type:

Article

FXR Mediates Adenylyl Cyclase 8 Expression in Pancreatic β-Cells.

Published in:

Journal of Diabetes Research, 2019, p. 1, doi. 10.1155/2019/8915818

By:

Kong, Xiangchen;
Li, Bingfeng;
Deng, Yushen;
Ma, Xiaosong

Publication type:

Article

Nuclear receptor FXR impairs SK‑Hep‑1 cell migration and invasion by inhibiting the Wnt/β‑catenin signaling pathway.

Published in:

Oncology Letters, 2020, v. 20, n. 5, p. 1, doi. 10.3892/ol.2020.12022

By:

QIANQIAN LI;
NINGBO LI;
YETING ZENG;
XINRUI WANG;
JIE LI;
HONGYING SU;
MEIQIN GAO;
XIONGFEI HUANG

Publication type:

Article

Effects and mechanism of the bile acid (farnesoid X) receptor on the Wnt/β-catenin signaling pathway in colon cancer.

Published in:

Oncology Letters, 2020, v. 20, n. 1, p. 337, doi. 10.3892/ol.2020.11545

By:

Mao, Jiayu;
Chen, Xueqi;
Wang, Chunsaier;
Li, Wenbin;
Li, Jingnan

Publication type:

Article

Activation of FXR promotes intestinal metaplasia of gastric cells via SHP-dependent upregulation of the expression of CDX2.

Published in:

Oncology Letters, 2018, v. 15, n. 5, p. 7617, doi. 10.3892/ol.2018.8342

By:

Zhou, Haining;
Ni, Zhen;
Li, Ting;
Su, Linna;
Zhang, Lianfeng;
Liu, Na;
Shi, Yongquan

Publication type:

Article

Transcriptome changes during peanut oral immunotherapy and omalizumab treatment.

Published in:

Pediatric Allergy & Immunology, 2022, v. 33, n. 1, p. 1, doi. 10.1111/pai.13682

By:

Björkander, Sophia;
Merid, Simon Kebede;
Brodin, David;
Brandström, Josef;
Fagerström‐Billai, Fredrik;
van der Heiden, Marieke;
Konradsen, Jon R.;
Kabesch, Michael;
van Drunen, Cornelis M.;
Golebski, Korneliusz;
Maitland‐van der Zee, Anke H.;
Potočnik, Uroš;
Vijverberg, Susanne J. H.;
Nopp, Anna;
Nilsson, Caroline;
Melén, Erik;
Peters, Rachel

Publication type:

Article

The Potential Role of Intestinal Microbiota on the Intestine-Protective and Lipid-Lowering Effects of Berberine in Zebrafish (Danio rerio) Under High-Lipid Stress.

Published in:

Metabolites (2218-1989), 2025, v. 15, n. 2, p. 118, doi. 10.3390/metabo15020118

By:

Gao, Chang;
Wang, Heng;
Xue, Xuan;
Qi, Lishun;
Lin, Yanfeng;
Wang, Lei

Publication type:

Article

Silybin Meglumine Mitigates CCl 4 -Induced Liver Fibrosis and Bile Acid Metabolism Alterations.

Published in:

Metabolites (2218-1989), 2024, v. 14, n. 10, p. 556, doi. 10.3390/metabo14100556

By:

Liu, Xiaoxin;
Xia, Ninglin;
Yu, Qinwei;
Jin, Ming;
Wang, Zifan;
Fan, Xue;
Zhao, Wen;
Li, Anqin;
Jiang, Zhenzhou;
Zhang, Luyong

Publication type:

Article

Fufang Muji Granules Ameliorate Liver Fibrosis by Reducing Oxidative Stress and Inflammation, Inhibiting Apoptosis, and Modulating Overall Metabolism.

Published in:

Metabolites (2218-1989), 2024, v. 14, n. 8, p. 446, doi. 10.3390/metabo14080446

By:

Men, Lei;
Gu, Zhihong;
Wang, Enhua;
Li, Jiwen;
Li, Zhongyu;
Li, Keke;
Li, Chunbin;
Gong, Xiaojie

Publication type:

Article

Metabolomics and Lipidomics Analyses Aid Model Classification of Type 2 Diabetes in Non-Human Primates.

Published in:

Metabolites (2218-1989), 2024, v. 14, n. 3, p. 159, doi. 10.3390/metabo14030159

By:

Tao, Peining;
Conarello, Stacey;
Wyche, Thomas P.;
Zhang, Nanyan Rena;
Chng, Keefe;
Kang, John;
Sana, Theodore R.

Publication type:

Article

Metabolic Clues to Bile Acid Patterns and Prolonged Survival in Patients with Metastatic Soft-Tissue Sarcoma Treated with Trabectedin.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 10, p. 1035, doi. 10.3390/metabo13101035

By:

Miolo, Gianmaria;
Buonadonna, Angela;
Scalone, Simona;
Lombardi, Davide;
Della Puppa, Lara;
Steffan, Agostino;
Corona, Giuseppe

Publication type:

Article

Specnuezhenide Ameliorates Age-Related Hepatic Lipid Accumulation via Modulating Bile Acid Homeostasis and Gut Microbiota in D-Galactose-Induced Mice.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 8, p. 960, doi. 10.3390/metabo13080960

By:

Deng, Xuehui;
Lin, Bingfeng;
Wang, Fang;
Xu, Pingcui;
Wang, Nani

Publication type:

Article

Upregulation of Taurine Biosynthesis and Bile Acid Conjugation with Taurine through FXR in a Mouse Model with Human-like Bile Acid Composition.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 7, p. 824, doi. 10.3390/metabo13070824

By:

Miyazaki, Teruo;
Ueda, Hajime;
Ikegami, Tadashi;
Honda, Akira

Publication type:

Article

Deciphering Gut Microbiome Responses upon Microplastic Exposure via Integrating Metagenomics and Activity-Based Metabolomics.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 4, p. 530, doi. 10.3390/metabo13040530

By:

Tu, Pengcheng;
Xue, Jingchuan;
Niu, Huixia;
Tang, Qiong;
Mo, Zhe;
Zheng, Xiaodong;
Wu, Lizhi;
Chen, Zhijian;
Cai, Yanpeng;
Wang, Xiaofeng

Publication type:

Article

Expression of STING in Women with Morbid Obesity and Nonalcoholic Fatty Liver Disease.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 4, p. 496, doi. 10.3390/metabo13040496

By:

Bertran, Laia;
Adalid, Laia;
Vilaró-Blay, Mercè;
Barrientos-Riosalido, Andrea;
Aguilar, Carmen;
Martínez, Salomé;
Sabench, Fàtima;
del Castillo, Daniel;
Porras, José Antonio;
Alibalic, Ajla;
Richart, Cristóbal;
Auguet, Teresa

Publication type:

Article

Hepatic Mitochondria-Gut Microbiota Interactions in Metabolism-Associated Fatty Liver Disease.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 3, p. 322, doi. 10.3390/metabo13030322

By:

Bellanti, Francesco;
Lo Buglio, Aurelio;
Vendemiale, Gianluigi

Publication type:

Article

Regulation of Human Endogenous Metabolites by Drug Transporters and Drug Metabolizing Enzymes: An Analysis of Targeted SNP-Metabolite Associations.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 2, p. 171, doi. 10.3390/metabo13020171

By:

Granados, Jeffry C.;
Watrous, Jeramie D.;
Long, Tao;
Rosenthal, Sara Brin;
Cheng, Susan;
Jain, Mohit;
Nigam, Sanjay K.

Publication type:

Article

Metabolic Role of Autophagy in the Pathogenesis and Development of NAFLD.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 1, p. 101, doi. 10.3390/metabo13010101

By:

An, Lingxuan;
Wirth, Ulrich;
Koch, Dominik;
Schirren, Malte;
Drefs, Moritz;
Koliogiannis, Dionysios;
Niess, Hanno;
Andrassy, Joachim;
Guba, Markus;
Bazhin, Alexandr V.;
Werner, Jens;
Kühn, Florian

Publication type:

Article

Obstructive Sleep Apnea, Circadian Clock Disruption, and Metabolic Consequences.

Published in:

Metabolites (2218-1989), 2023, v. 13, n. 1, p. 60, doi. 10.3390/metabo13010060

By:

Malicki, Mikołaj;
Karuga, Filip Franciszek;
Szmyd, Bartosz;
Sochal, Marcin;
Gabryelska, Agata

Publication type:

Article

Fecal Bile Acids and Neutral Sterols Are Associated with Latent Microbial Subgroups in the Human Gut.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 9, p. 846, doi. 10.3390/metabo12090846

By:

Breuninger, Taylor A.;
Wawro, Nina;
Freuer, Dennis;
Reitmeier, Sandra;
Artati, Anna;
Grallert, Harald;
Adamski, Jerzy;
Meisinger, Christa;
Peters, Annette;
Haller, Dirk;
Linseisen, Jakob

Publication type:

Article

Nuclear Receptor Pathways Mediating the Development of Boar Taint.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 9, p. 785, doi. 10.3390/metabo12090785

By:

Bone, Christine;
Squires, E. James

Publication type:

Article

Farnesoid X Receptor, Bile Acid Metabolism, and Gut Microbiota.

Published in:

Metabolites (2218-1989), 2022, v. 12, n. 7, p. N.PAG, doi. 10.3390/metabo12070647

By:

Mori, Hideki;
Svegliati Baroni, Gianluca;
Marzioni, Marco;
Di Nicola, Francesca;
Santori, Pierangelo;
Maroni, Luca;
Abenavoli, Ludovico;
Scarpellini, Emidio

Publication type:

Article

Disparate Metabolomic Responses to Fructose Consumption between Different Mouse Strains and the Role of Gut Microbiota.

Published in:

Metabolites (2218-1989), 2021, v. 11, n. 6, p. 342, doi. 10.3390/metabo11060342

By:

Ahn, In-Sook;
Yoon, Justin;
Diamante, Graciel;
Cohn, Peter;
Jang, Cholsoon;
Yang, Xia

Publication type:

Article

Regulation of Hepatocyte Nuclear Factor 4α Attenuated Lipotoxicity but Increased Bile Acid Toxicity in Non-Alcoholic Fatty Liver Disease.

Published in:

Life (2075-1729), 2022, v. 12, n. 11, p. 1682, doi. 10.3390/life12111682

By:

Roh, Yoon Jin;
Kim, Yun;
Lee, Jae Sun;
Oh, Ju Hee;
Lee, Seung Min;
Yoon, Eileen Laurel;
Lee, Sung Ryol;
Jun, Dae Won

Publication type:

Article

Editorial: Flavonoids: From Biosynthesis and Metabolism to Health Benefits.

Published in:

Frontiers in Plant Science, 2021, v. 12, p. 1, doi. 10.3389/fpls.2021.727043

By:

González-Mas, M. Carmen;
Blázquez, M. Amparo;
López-Gresa, M. Pilar;
Mena, Pedro;
García-Viguera, Cristina

Publication type:

Article